Basic Information

Insect: Hirtodrosophila confusa
Gene Symbol: zfh1
Assembly: GCA_035043065.1
Location: JAWNNI010000066.1:8901427-8905756[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 3.3e-05 0.0027 18.5 1.0 1 23 145 167 145 167 0.97

2 15 0.001 0.082 13.9 1.2 3 23 175 195 173 195 0.94

3 15 0.00011 0.0089 16.9 0.1 1 23 363 385 363 385 0.98

4 15 0.013 1.1 10.4 2.5 1 23 391 413 391 413 0.98

5 15 0.00049 0.04 14.8 5.2 1 23 444 466 444 467 0.94

6 15 0.0029 0.24 12.4 1.8 1 23 511 533 511 533 0.95

7 15 0.021 1.7 9.7 1.3 1 23 539 562 539 562 0.97

8 15 0.032 2.6 9.1 0.4 3 19 571 587 570 588 0.95

9 15 0.00019 0.016 16.1 5.6 1 23 597 619 597 619 0.97

10 15 0.049 4 8.5 1.2 2 23 625 646 624 646 0.96

11 15 1.1e-05 0.00091 20.0 1.0 1 23 655 677 655 677 0.98

12 15 0.0013 0.1 13.5 0.1 3 23 685 705 683 705 0.97

13 15 6.7e-05 0.0055 17.5 0.5 1 23 711 733 711 734 0.95

14 15 0.092 7.5 7.7 0.5 1 23 744 766 744 766 0.97

15 15 0.00017 0.014 16.3 0.6 1 23 1281 1303 1281 1303 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	3.3e-05	0.0027	18.5	1.0	1	23	145	167	145	167	0.97
2	15	0.001	0.082	13.9	1.2	3	23	175	195	173	195	0.94
3	15	0.00011	0.0089	16.9	0.1	1	23	363	385	363	385	0.98
4	15	0.013	1.1	10.4	2.5	1	23	391	413	391	413	0.98
5	15	0.00049	0.04	14.8	5.2	1	23	444	466	444	467	0.94
6	15	0.0029	0.24	12.4	1.8	1	23	511	533	511	533	0.95
7	15	0.021	1.7	9.7	1.3	1	23	539	562	539	562	0.97
8	15	0.032	2.6	9.1	0.4	3	19	571	587	570	588	0.95
9	15	0.00019	0.016	16.1	5.6	1	23	597	619	597	619	0.97
10	15	0.049	4	8.5	1.2	2	23	625	646	624	646	0.96
11	15	1.1e-05	0.00091	20.0	1.0	1	23	655	677	655	677	0.98
12	15	0.0013	0.1	13.5	0.1	3	23	685	705	683	705	0.97
13	15	6.7e-05	0.0055	17.5	0.5	1	23	711	733	711	734	0.95
14	15	0.092	7.5	7.7	0.5	1	23	744	766	744	766	0.97
15	15	0.00017	0.014	16.3	0.6	1	23	1281	1303	1281	1303	0.98

Sequence Information

Coding Sequence: ATGAACAATCAGGACTATGGCGGCATCCAATGGATACAGCAGCACGCAACCGACGATATGCTGCAGGGCGCCTCCGCCGACGGTGAGGTGACGTCCGCTTATCTGGTCAGTGGCAATGCAACCGACGAGGATCTCGATCAAATGGCTGCcgagaatctcatcttcaTGGCCCGCGATGGCCAGCTGACCGAGATTATAGCCGCCAACGAGACCGGCGGCGGCACCGTGCTGATCACGGACAGCGGCACCGTCACCTATGCCGAGTCATTCGACGATGATGCCCAGGTGGTCACCGAGGAGATCATCACTGATGATTGGGTGCAGCATCAGGGCGCCGAGCGCGTGGAAATCGCTGCCGAGCAAATAGCTGGAAACAGCAGCTCACTGGAACTGCTGGATATGGAGCAGGATGAGTACACGGCGCTGCGTCCTTATCCCTGTGACTTCTGTAGCCGGCGCTTTCGCAAGAAGGCCAGCCTCAATAATCATATGCTGGCGCATCAAAACGATCGTCCGCATCTGTGTAAACTTTGTGGTGCGCGCTTTTCGCGTCGCGCCGAGCTCATCAGTCACTTTAAGGCGCATGCCGAGGCACAGGACGCTGCGGACGCGGAAGCCGCCGCGGCGTCGGTGTCAGCAGCTGCTATAAAATTTgaaccgcagcagcagcagcagcatcaaacACAAATCGATGATCACTTCTACGAACAGGAATGGCCTTCATATcaggagcaggaacaggaTCAGGATCAGGAGCAACAACTGGAGCAGGAGCACGAGCAGTTGCCTATTGACAGCCAAGTTGCGCAGTCGGCCTGCTATGCAGCGGTTAGCGCTGTGGCAGCGCCAACAGCAGCCCGCGGCCGCATTAGTCGCCTCAAGCCCAAGGAGGAGAGCACGCAGTACATTGTGATTGCCGAAAAGCAAACCCCCGACGATTTGCCACAGTACATGGATTCCGAAGAGCTACCGCCGCCGTTAACTGCCAACACAACGTCCCACGATGCGACTCACACGACAGACAGTGGCCCAGCCGCTGTTGCGGCACATCCGCCACGTTTCCCCGTGCTCGACGACAGCAAACCCTTTGTCTGCCAGCAGTGCGGCTTGGCATTTGCGCGCGAAAAAGCGCTGGTTTCTCATATCAAGAATCATCGCGTGGACTCTCCCTTTGAGTGTAACCAGTGTCAGGAGATGTTTTGGGACACTTATAGCCTGCATGAGCATCAGAAGACGCATCAGTTCGAGGAGAGCAACTCAGAGTACGATCCAGCGTCGGCGGGGGAGGATAGTGCCAGCGAATCGGAGTCGGAACAGCTTTATGGTGAATTTTTCTGCAGCGAATGTGGCATATCCTTTCACAGGCAGGACCTGCTGCGGCGCCATAGCAAGCAGCACCACAAACTGGCCGCGGTTAACGCTACGGCTACGTTCAACTCAACGGATGTCGAGGGCAgcgccgatgccgatgccgatgctgatgccgatgccgatgctgatgctgatgctgaaaATGCCAAAGATGCCCCACACTGCTGTCATACCTGCGGCAAGTCCTATCCCAGCGCATTGGAGCTGCTCGCCCATGCCGAGATTCATGCACGGTTTCCACCTTTCAAATGCGTGTTGTGCGGTGTTAGTTTTTATGAGGAGCAAGCCATTAAGCGGCATCTGCACACCCGTCATCCACATGAACTCAAGCCGAACTCTTGCGTGCTGTGCGGCAAGGAGTGCCGCGATCGCAAGGCGCTGATCAAGCACGCCTGGGATCACTCGCGCGAGAAGTGCCACTCGTGCTCCAAATGCGGCAAGAACTTTCACAACAAGGCGCGCTTGAAGCGGCATATGGCTTCGCATCGCGACAAGTCGGTGGTGTGCGAGGTGTGCCACGAGGAGTTTCCCGATGGCCGCACGCTATCCAATCACCGCCATTCGCACAGCACAACCTCGCCGGGTAAACTGTTCCCCTGCCATGAGTGCGGCAAGACCTTTGGCTCTCGCAGCTCGCAGCAGATTCATGTGCGCATTCACACCGGTGAGCGGCCATATGGATGTCGCTATTGCTGGAAAGCCTTTGCCGATGGAGGTACGCTCCGCAAGCACGAGCGCATACATACTGGGGAGAAGCCTTATGCCTGCTCCGTTTGTCCACGTGCCTTTAATCAGCGTGTAGTGTTGCGTGAGCATATACGCTCGCATCACTCGGGGCTGGATGCGGAGCGTGGCACCTATCACTGCACCGTCTGCAGGGCAGACTTGTCCTCATCCAATGAGCTTATACAGCATCTCATTCAACACAGCGACACCAACACCGCCAAACAGCGACAGCCTATTACCGGACCCCGCAAGTACAAGCGTCGTAGGAAACTGCAGCCTCATGAGATAGCGCACCTGCGTGCCGAACACAAAGATGGCGATGAATATGCCAGCGACATTGATCTCTGCGACTTGGATGTGGAGAATGTGGACGATCTCTTTGATGGGGAAGAGCCATCCCCACCCAAAAAGGAGAAGCGCAAGCGTAACGCAGCAGGTCAAGCTAAGAACGTGGCAAATGGTGATGCAGCGCCCGCCCAAAACAACTCTATTGCAGTCAAATCCGCGAATGGCAATTCAGATCGTCTGTGGGAGGATAAATTCATGCAGGcaaatggcaacagcaacgtTGGCAATCAGCTAAATGATGATGCCTACAAGAGCCTCTATCAGATCGATTCGCTAGTGGTGGTTAATGATACCACGCTGCAGCCAGTTAGCTCATCAATTGGTATTGCCAAAACGCGACGCAGTGGCAAGCAGCCTCAAACGCAGCGGCAGACGCAAGCCGACAACAGCGACAAGTCAGAAGCAATGGCTACTGATGAGTATGTCAAACTTAGCATCTCCTCTACCTCCAGCAGTCGCAGCAACAGAAAGAAGACTGGCAAGGCGTCCAAGAATGCAACCACAACAGCGTCCACTTCCAGCAGCTCGCGTCCACGTATGATACATACGGAAAAGTCACGCCTGCCACAGGAGCATACGTCGAAGAAGACGCGAAACCGGACTTACATCACGCGCACCAGCGAGAGCAGCCAGCTGGGTCTGGTCAAGTCGCGCATTGTGGATGACTACGAAATTATTTCACCTGCCACTCAGCCACCTAATCAGATAAGCTCCAGTCCGCTGCACATtaagcaggagcaggagcatcAGCGCGTGCAGCTAATGTATGATGATACGCATCTTCTTATCGATACGGCTCTGTTGCGGGAGAAGACCTATGAGAAGTTCAATCCCAGCATTGTCAATGATCTTGAGGAGATACTGCGTAGCCCTCTCAAACATGATCGCAATGCGCGACTCCGTTTCACCAGCGAATCGTCGACAACGCCACAGTTTTTGCCCGAGGAGGAGCAGAACCTTATTAAAATAGAACCGACGTCGCCGGATCTCCGTGAAATGGTTGAGAGCCAGCAGCGCGTCACTGCCACAGGCCACACAGCCACAACCAGGACATCGTCGTCGACGGTGCGCACCTCGCGCCATCTGCGACAGCTTACCGCCAACTCAAGCTCACGAGCAGCAAcaaagcgcagcagcagcagcaaattaGTTTCTGCATCCGGTTCCAAGAAATCAAACGTCAATTCATCCCCTTCCGTTGCAGAGAGCAAAGCCTCCAGTTCTTACCTGAGCTATGCCGTCGACTCGTACACTGTGAACGTAGCTGCCAGCGCAAACTCTTCAGATGTCAGTTCCGGTTTCTTTTCCATTTCTGAGGTGGTATCCGCAGCAGATGCCGCCGATGCAGCGGCCAAGGCAGCAGCGGCCAACAAAACGGAGCGCAGGACGCGTTGCTTTGAGTGTGAAATGTGCTCGACCAAATTTCCTGATCGTGCCCAGCTTTTAGAtcatatgcatatacacatctaa
Protein Sequence: MNNQDYGGIQWIQQHATDDMLQGASADGEVTSAYLVSGNATDEDLDQMAAENLIFMARDGQLTEIIAANETGGGTVLITDSGTVTYAESFDDDAQVVTEEIITDDWVQHQGAERVEIAAEQIAGNSSSLELLDMEQDEYTALRPYPCDFCSRRFRKKASLNNHMLAHQNDRPHLCKLCGARFSRRAELISHFKAHAEAQDAADAEAAAASVSAAAIKFEPQQQQQHQTQIDDHFYEQEWPSYQEQEQDQDQEQQLEQEHEQLPIDSQVAQSACYAAVSAVAAPTAARGRISRLKPKEESTQYIVIAEKQTPDDLPQYMDSEELPPPLTANTTSHDATHTTDSGPAAVAAHPPRFPVLDDSKPFVCQQCGLAFAREKALVSHIKNHRVDSPFECNQCQEMFWDTYSLHEHQKTHQFEESNSEYDPASAGEDSASESESEQLYGEFFCSECGISFHRQDLLRRHSKQHHKLAAVNATATFNSTDVEGSADADADADADADADADAENAKDAPHCCHTCGKSYPSALELLAHAEIHARFPPFKCVLCGVSFYEEQAIKRHLHTRHPHELKPNSCVLCGKECRDRKALIKHAWDHSREKCHSCSKCGKNFHNKARLKRHMASHRDKSVVCEVCHEEFPDGRTLSNHRHSHSTTSPGKLFPCHECGKTFGSRSSQQIHVRIHTGERPYGCRYCWKAFADGGTLRKHERIHTGEKPYACSVCPRAFNQRVVLREHIRSHHSGLDAERGTYHCTVCRADLSSSNELIQHLIQHSDTNTAKQRQPITGPRKYKRRRKLQPHEIAHLRAEHKDGDEYASDIDLCDLDVENVDDLFDGEEPSPPKKEKRKRNAAGQAKNVANGDAAPAQNNSIAVKSANGNSDRLWEDKFMQANGNSNVGNQLNDDAYKSLYQIDSLVVVNDTTLQPVSSSIGIAKTRRSGKQPQTQRQTQADNSDKSEAMATDEYVKLSISSTSSSRSNRKKTGKASKNATTTASTSSSSRPRMIHTEKSRLPQEHTSKKTRNRTYITRTSESSQLGLVKSRIVDDYEIISPATQPPNQISSSPLHIKQEQEHQRVQLMYDDTHLLIDTALLREKTYEKFNPSIVNDLEEILRSPLKHDRNARLRFTSESSTTPQFLPEEEQNLIKIEPTSPDLREMVESQQRVTATGHTATTRTSSSTVRTSRHLRQLTANSSSRAATKRSSSSKLVSASGSKKSNVNSSPSVAESKASSSYLSYAVDSYTVNVAASANSSDVSSGFFSISEVVSAADAADAAAKAAAANKTERRTRCFECEMCSTKFPDRAQLLDHMHIHI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00579414;
90% Identity: iTF_00805345;
80% Identity: -