Hhis003564.1
Basic Information
- Insect
- Hirtodrosophila histrioides
- Gene Symbol
- ftz-f1
- Assembly
- GCA_037075165.1
- Location
- JBAMCL010000189.1:3130532-3149784[-]
Transcription Factor Domain
- TF Family
- SF-like
- Domain
- zf-C4|SF-like
- PFAM
- AnimalTFDB
- TF Group
- Zinc-Coordinating Group
- Description
- The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 3 0.13 1.4e+03 -1.4 21.3 45 158 24 144 4 161 0.60 2 3 1.6e-19 1.7e-15 57.6 0.4 1 79 335 412 335 446 0.75 3 3 4.9e-72 5.2e-68 230.6 1.4 157 408 546 790 517 792 0.91
Sequence Information
- Coding Sequence
- ATGTTATTAGAAATGGATCAACAACAGGCGACTGTACAGTTTATATCGTCGCTGAATCTGTCGCCATTTAGCatgcagctggagcagcagcagccagcgagtCCAGCGCACAGCAACaccaatgccaacaacaacaacagcagcaacaacaacaacgcggccaacaccaacaacagcagcagcagcaacaacaacaacgataccGATACAAATGTCTTAAGCAATTCCGATAACGATTACAGCGCCTACACGCTGCAATTGAGcaatcatcagcagcagcagcaacatcacacgcatcaccagcagcagcagcagcaacaacaacaacattaccAACAACCGAATattgccaacaacaataacaacaacaacacaaatgcTGCCAATCAATTCAATGCCTCCTCCTATtcgtatatatacaatttcgATTCACAGTATATATTCCCGACAGGCTATCAGGAAACAAACTCATCCCATTCGCAGCAGAGCGGTCATGGTGGCGGTGGCAACGCTGCCGCAGCGacatctggcaacgctggtCAACTTTTAAATGGCAttgctggcagcgctgctggcAATGGTTATATGTTGCTGCCACCAGCCGCTGGTGGCGCTGCTGGCGCCGCTGCTCACTTGTCCGGCGGCAATGTGGGCGCCAATGGGGGCGCGCCCGGTGCGGGCAATGCTgcgggcggcggcggcggcggtgtcGGTGGCGGCCATCATGGCGGCACCAGCGCCAGCTCAGGCGGCGGCGGTGAGGCCATCGATTTTAAGCATCTGTTTGAGGAGCTCTGCCCCGTTTGCGGGGACAAGGTGAGCGGGTATCATTACGGCCTGCTCACCTGCGAGTCCTGCAAGGGTTTCTTCAAGCGCACCGTTCAGAACAAAAAGGTCTACACTTGCGTCGCGGAGCGCTCCTGTCATATCGATAAGACCCAGCGCAAACGTTGTCCATACTGTCGATTCCAAAAGTGCCTGGAGGTGGGCATGAAACTAGAGGCGGTTCGAGCGGATCGCATGCGCGGCGGCCGCAACAAGTTTGGACCCATGTACAAGCGGGATCGGGCGCGGAAGCTGCAGGTgatgcggcagcggcaactggCGCTGCAGGCGCTGCGCAGTTCGATGGGGACGGACATTAAGCCGACGCCGCTGTCGCCGGGCTATCAGCAAGCATATCCAAATATGAACATTAAGCAGGAAATACAAATACCTCAGGTATCCTCACTCACACAGTCGCCGGACTCCTCGCCCAGCCCCATTGCGATTGCCCTGGGTCAGGTGAATGCGAGCGGGGGCGGTGTGATAGCCACGCCCATGAATGCCGGCAATGTGAGTggcggcaatggcaatggcagctCCTCCTTGGGCAgtggcaacaacggcaacagcagcaacaacaacaacaacagcagcagcagcacaggcaGCGGAAGCGGCGGCGTCGGCGGCGGAGGTGGCAACAAtgctggcggcggcggtggcaacaacaataacaatggaGCCGACGGCCTGCAACGCAACGGAAACGGgggcaatggcaacagcaacagcagctgccacgAAACCGGCACAGGATCTCTCCAAAACTCCGCCGAATCGAAATTGTGCTTCGACTCTGGCACACATCCATCTAGCACAGCCGATGCGCTCATCGAGCCACTGAGGGTCTCACCGATGATACGGGAGTTTGTGCAATCGATCGATGATCGGGAATGGCAGACGCAGCTTTTTGCGCTGCTGCAGAAGCAGACGTACAATCAAGTTGAAGTGGATCTCTTTGAGTTAATGTGCAAAGTGCTCGATCAGAATCTGTTCTCGCAGGTGGATTGGGCAAGAAACACCGTCTTCTTTAAGGATTTGAAGGTGGACGACCAAATGAAGCTGCTGCAGCACTCGTGGTCCGATATGCTCGTCCTGGACCATCTGCACCACCGCATCCACAACGGCCTGCCCGACGAGACCCAGCTGAACAACGGCCAGGTCTTCAACCTGATGAGCCTCGGCCTCCTGGGCGTGCCCCAGCTGGGCGACTACTTCAACGAGCTGCAGAACAAGCTGCAGGATCTGAAGTTCGACATGGGCGACTATGTGTGCATGAAATTcctaatattattaaatcCAGATGTGCGCGGCATTGTCAACAAGAAGTTCGTCCTCGAGGGACATGAGAATGTCCAGGCGGCGCTGCTGGACTACACGCTGACGTGTTATCCCTCAGTTAATGACAAATTCAGGAGGCTATTGAACATACTACCGGAAATCCACGCCATGGCCGCGAGGGGCGAGGAGCATCTGTATTCAAAGCACTGTGCAGGCAGTGCGCCCACGCAGACGCTGCTCATGGAGATGCTGCACGCCAAGCGGAAGGTGTAA
- Protein Sequence
- MLLEMDQQQATVQFISSLNLSPFSMQLEQQQPASPAHSNTNANNNNSSNNNNAANTNNSSSSNNNNDTDTNVLSNSDNDYSAYTLQLSNHQQQQQHHTHHQQQQQQQQQHYQQPNIANNNNNNNTNAANQFNASSYSYIYNFDSQYIFPTGYQETNSSHSQQSGHGGGGNAAAATSGNAGQLLNGIAGSAAGNGYMLLPPAAGGAAGAAAHLSGGNVGANGGAPGAGNAAGGGGGGVGGGHHGGTSASSGGGGEAIDFKHLFEELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNKKVYTCVAERSCHIDKTQRKRCPYCRFQKCLEVGMKLEAVRADRMRGGRNKFGPMYKRDRARKLQVMRQRQLALQALRSSMGTDIKPTPLSPGYQQAYPNMNIKQEIQIPQVSSLTQSPDSSPSPIAIALGQVNASGGGVIATPMNAGNVSGGNGNGSSSLGSGNNGNSSNNNNNSSSSTGSGSGGVGGGGGNNAGGGGGNNNNNGADGLQRNGNGGNGNSNSSCHETGTGSLQNSAESKLCFDSGTHPSSTADALIEPLRVSPMIREFVQSIDDREWQTQLFALLQKQTYNQVEVDLFELMCKVLDQNLFSQVDWARNTVFFKDLKVDDQMKLLQHSWSDMLVLDHLHHRIHNGLPDETQLNNGQVFNLMSLGLLGVPQLGDYFNELQNKLQDLKFDMGDYVCMKFLILLNPDVRGIVNKKFVLEGHENVQAALLDYTLTCYPSVNDKFRRLLNILPEIHAMAARGEEHLYSKHCAGSAPTQTLLMEMLHAKRKV
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00485910;
- 90% Identity
- iTF_00805241;
- 80% Identity
- iTF_00805241;