Basic Information

Gene Symbol
Znf574
Assembly
GCA_037043425.1
Location
JBAMBM010000770.1:1219227-1219616[+]

Transcription Factor Domain

TF Family
zf-GAGA
Domain
zf-GAGA domain
PFAM
PF09237
TF Group
Zinc-Coordinating Group
Description
Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 3 0.00032 1.6 9.1 0.2 27 48 12 33 5 38 0.87
2 3 0.00011 0.52 10.6 0.7 18 52 59 94 52 94 0.78
3 3 1.3e-06 0.0063 16.8 0.2 20 48 90 118 86 123 0.88

Sequence Information

Coding Sequence
ATGACCAtaaacacaacacagcacgATCTCATGTGTGATAGATGTGGTCTTAAGTTTAAGCAGAGCCGTCAATTGCGGGAGCACATAACTATTGCACATAAGGGCCTGCGTCCACATCAGTGCAGCAAGTGTTCAAAAAATTATGCACGCAAAAGCCATCTCAATGATCACATGCGCtcacatacgcaacagcgtgATTACATATGCAAAATCTGCCTGAAGGCCTTCAAACGGAGCCAGGAACTCACTCGCCATAAACGGCTGCACCAGGAGGAGAAACCATACGGCTGCCCGATGTGTCTGGCCACATTTCGTCAACATTCCGGCCTGTATAATCACAAGAGAAGCAAACATGACAAGGTTCCAGTTCAAAGAGAAGGTGTTGCTTAG
Protein Sequence
MTINTTQHDLMCDRCGLKFKQSRQLREHITIAHKGLRPHQCSKCSKNYARKSHLNDHMRSHTQQRDYICKICLKAFKRSQELTRHKRLHQEEKPYGCPMCLATFRQHSGLYNHKRSKHDKVPVQREGVA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00804689;
90% Identity
iTF_00804689;
80% Identity
iTF_00804689;