Hdun009614.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Hirtodrosophila duncani
Gene Symbol
RREB1
Assembly
GCA_037043425.1
Location
JBAMBM010000704.1:975879-982233[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.042 2.6 8.8 0.8 1 21 254 274 254 276 0.93
2 12 0.0011 0.07 13.8 0.2 1 23 286 308 286 308 0.98
3 12 9.5e-05 0.0059 17.1 7.3 1 23 314 336 314 336 0.98
4 12 4.5 2.8e+02 2.4 4.6 2 19 556 573 556 575 0.97
5 12 0.048 3 8.6 0.0 1 23 723 745 723 745 0.97
6 12 2.3e-05 0.0014 19.1 1.2 1 23 755 777 755 777 0.99
7 12 0.00097 0.061 14.0 2.0 1 23 783 806 783 806 0.97
8 12 0.0087 0.54 11.0 1.7 1 23 1054 1077 1054 1077 0.95
9 12 0.0001 0.0063 17.1 0.3 2 23 1421 1442 1420 1442 0.97
10 12 0.17 11 6.9 6.3 1 23 1448 1471 1448 1471 0.97
11 12 0.0099 0.62 10.8 0.5 3 23 1674 1694 1672 1694 0.96
12 12 0.0016 0.098 13.3 4.8 1 23 1700 1722 1700 1722 0.99

Sequence Information

Coding Sequence
ATGCTGgccacacagcagcagcaacaacagaagcagccaAATAGCACAGCACATGGCGATAGCGAAATGGAGCGCCAGCGACGGGAATCCACCACCTCGGAATCGTCGCTGGAGCATCTGGACCTGGGACGCACACCAAAGAAactaagcagcagcagcggtgcACCGCAGCCGACGTCAACGCCGCACgaagccaccgccaccgctaCATCCACATCGGCATCGGCGTCGGCGTCGTCATCCACAACGCGCAAACGCAAgctgcggcagcaacagcagcagctgcacttGCTCTCCGATGAGGACGAATCAGCAACAGAGTTGCAGCagtcacagcaacaacaacaccagcagcagcagctggaggcCACATCGACAGCGCAGCGACTGCGCCACAAGCAGCGACGCAACGCCGCTGCCAATGCCAGCATCGTGGTCGACTATGGCGCCAACGATGCCAGTTCATTGCGTAAAAAATTTCGCCTGAACCTGAATCGCAGCAATGCCAGTAGTGGCAGTGCCATAGCTGAGCTTTCCGAGTCAGGCTTTGTGGATGGCAGCGCTCACAGTGGCTACCTGCTTggcaacagtagcagcagcaacgccaACAGTACCGCCTCCGCCAATGCACCAACGTCGACAAAGACTCTGGCCtccggcagcagcagttctGCTTCGGGTTCGGGTGGCTCCTCGCCGCAAGGCTTGTGCCTGTCCAGCGCCGAGTCTGGAATTGGTGCCGGCGACGAGCATATGAAGTATCTGTGCCCCATCTGTGAGGTTGTCTCGGCCACGCCCCACGAGTTCACCAACCACATACGTTGCCACAATTATGCCAACGGCGATACTGAGAACTTCACCTGCCGCATCTGCTCCAAGATACTTTCCTCAGCCTCCTCACTGGACAGACACGTCCTGGTGCATACTGGCGAGCGTCCTTTCAACTGTCGCTACTGTCACCTGACCTTCACCACCAATGGCAACATGCATCGTCATATGCGCACCCAcaagcagcaccaacagtCCTCCTCGTCCACGACGGCTCAAGGCCAACAGAcgcattcccattcccaacaacaacaccagcgaCGCCAGCAGCAGAatggtggcagtggcagtaaCGGCAATGGCGGCGGCCCACTGGCTGCACCCAATCGCGCCGAGAGCTATGAGAGTGATGCCAGCTGCTCCACGGATGCGTCCAGTGCCAATAGCCATAGCAGTTGCTCCCAgaccaacaataacagccacaaaacgaacaacaataacaacaccagTCAGAAGAACAATGATTCATTGAGCAAGCAGCGACGCCCCAAGACCACCATCAATAACAATATCATAGACGATGTTGACGAGGAGgatgatgaggaggaggaggaaGAGCATGCCGAAGACgctgatgtggatgatgatgtcGATTccgatgcagatgcagatggcGTTGCTGACTCGCATGCcgatgtggctgtggccaaGCCTCTGTCCATAACCAGCACTCCAGATGTGGCCACTCTGCTGGCGGGTGCCGGCTTCCCCTCGGAAGCTACCTCGCCGGTTCCCAGCAACCAACTAATCAGCTGCCCGGCCTGCGTTGCCTCCGACTTTGATACGCTGGCCGCCTTGTGCCGTCACCTGGATGCCCAGCATTCGGATATACCCGCCAAGTGTCGCGACTGCGAGGTGATCTTTGCCACACATCGTCAGCTCCAGTCGCACTGCTGTCGCGGTGCCATGGGTCACCTGCCGCCCATGCCGCCCCTGGGTGCCAGCAGCTCGCCACTGCATCATGAGGAGGATCACGATCAGGATCAGCAGGATCGCAAGCACAGCATCGAATTGGACGCAGAGACGGAGGTGGAGAAGCAGCGTGAGGACTTCTTCTATCAGCTGTCTCTGAAGGGAAAAACGgggtccgtgtccgtgtcggCGTCACCATCGCCCTCGCCCATCAAGCATGAGCCGGCGGACAGCAAGGATCTGGCTGATATACAGAGCATACTCAATATGACTAGCTCCAGCTGCACGTCCAGCTTTCTGCGCAACTTCGAGCAGTCCGTGAATACGCCGTGCTCTAGCCAATACAGCCTAGATGGGCGAGATGGCGAAGAGGAGGCCCAGGATGCCTTCACCTCCGAGTTCCGTCGCATGAAACTGCGCGGCGAGTTCCCCTGCAAGCTGTGTGCCGCCGTCTTTCCCAATCTGCGCGCCCTGAAGGGCCACAACCGGGTGCACCTGGCCGCCGTCGGTCCATCGGGTCCGTTCCGCTGCAACATGTGTCCCTACTCCATTTGCGACAAGGCCGCCCTGGTGCGGCACATGCGCACCCACAACGGCGATCGACCTTATGAGTGTGCTGTCTGCAATTATGCGTTCACCACGAAGGCCAACTGTGAGCGACACCTGCGCAACCGTCACGGCAAGACGTCTCGCGAGGAGGTGAAGCGTGCCATTGTCTACCATCCGGCGGAGGATGCCAGCTGCGACGATGGCAAGTCGTCGCGTCTCGGCGATCCCTCCGATCTGGCCGATATCAGCTTCCGATCGAATtcgccgcagccgcagcctctGCTGGAGAGCTCATGCTCCTCCTCGTCACAACTGAAGCACATGCTCATGACTGAGCccatcaagcagcagcaggcgccaCAGCAGCAACCCCCACTCAAGATTCAGGTAAAGAGCCTGGATCAGTTGGTGGACAAGCCGTTGTCCGGGGCCGCCGCCACTGCCATGGATCTCAGCATGGATGCCTTGGACCTGAGCAAGAAGCCCACTGCGCCAGCCACAGCACAAGCAGCCGTTGGTTCACCAACGGCGGCAGCCACCCCAGTGCCAGAGCTGGCCGCCGctttggagcagcagcagttcctactcgcccagcagcagctggccgGCGACGCCGCCTCCCAGTACATGCAGCAGCTGTTCCGCAATCTGATGTTCCAGCTGCCGCCGAGTGTTCCATTCTTCAACTTTATGGCGCCGCCAGCGGGCCCAGACAAGCCGCCCCAGCTCAGTCCCCAGCCACCGCGCTTGCCGCCAATGCCAGTGGGCATGGGCGTACCCATGCCGGCCGGTGGACCCGTAAAGATGGTCATCAAGAATGGCGTCCTAATGCCTAAGCAGAAGCAGCGTCGCTATCGCACCGAACGTCCCTTTGCCTGTGCCCACTGCTCGGCGCGGTTCACCCTGCGCTCCAACATGGAACGCCACGTGAAGCAACAGCATCCTCAGTTCTATGCCCAGCGCCAGCGTGGTGGCCATCATGTGATGcgcggacgtggtgcctccagcgctgcggcagcagctgcggccgcagcagcagcagccgccgccatGGGTAACCATCATCATGCGGGCGGACATCATCATGGCGGCATGGGCAATGCGCCCATCTCCGAGCAGGTGAAGTACGCCATTCTGGCCCAGCAGCTGACGCGCAAGGATACGGATCTTTTGCACCAGGCTCTGGCCCATGGCTCCAGCAGCGTGGCCAGCAATCCGCTGCTGCATTTCGGTTACGCCGCGGCGGGCAATGGTCATGTGCCAGGCGCAGTCCCAGTGCAGAGCCAGGCACAGAGCAGTGTcatggatgatgatgagcccAAGCTGGTGATTGACGAGGATGAGGCCGAAGAGATAGAGGATTTTGATGAAGTCGATGAGGAAGACgaagatgacgatgacgaaCTGGAGACAATGGAGGCTGAGCGAGAGCGGGAACGCGTCCAGGCTAAGCCCGCTGTGGAACAGCTACCGCAGAGCACTGAGGTGGCTAGAAAGGTGGCCGACACCATCTTAGAGCAGGCCATCAAAGCCGGCAAGTCGAGTCCCCATCCCAGTCCCACTCCAGTGCAAGCGCCGCCCAGCCGCAATGCCACTCCCAAGCCACCAGAAGCGACTCCTCCGCCGCCGCACACCATGAAAACCATGATAGCCCAGGTGGAATCGGTGGCCAAGTCGCTCAAGGATGTAGCCAGCTCTCCGTTCAAGGATGAGTCGGTTGATCTGGTGCCGGTGGCCAAGCTGGTCGACAATGCCACCAGCAGCCAGATGAGCCTCAGCTTCAACAGCTATTTCCGTCCCAGCGACGTGGCCAATCACATGGAGCAGAGTGACGAGGAGGGCCTCGTCGCCTCCGGGAGTGCCAGCGAGAGCAACAACTCCGGCACCGAGGATgtgaccagcagcagcagcggcggcagcggcaacgaGCCCAAGAAGAAGTCCGCCTACAGTCTGGCCCCCAATCGCGTCTCCTGCCCCTACTGCCAGCGTATGTTCCCCTGGAGCAGCTCGCTGCGTCGCCACATACTCACCCACACGGGCCAGAAGCCCTTCAAGTGCTCCCACTGTCCGCTGCTCTTCACCACAAAGAGCAACTGCGATCGCCATCTGCTGCGCAAGCATGGCAACGTGGAGTCCGCAATGTCAGTCTATGTGCCGGCCGAGGATGTCAACGAGCCCATACCAGTGCCCAAGTCCGTGGAAGAGATCGAGCTGGAAGAGCAGCGCCGTCGCCGCAAGGAGCAGGCCGAGCAAGAGGAACGCCTGGAGCGTGAACGTCGCGCCCAGCAGGAACGCGAACGCGAACGGGAACGTGAGCGAGAACGTGAGAGGGAACGTGAAAGGGAACGCGAACGTGAGCGAGAGCGGGATCAGCTCCTGCAGCAGTTGGCCGCCGCCGCTCAGCTGACGCAGCAGATGAATGCcgccgcagctgcagctgcctcGTCcggcaacaccaacaatgcCGCTGAGACCAACGGCGGCGATCTGCCGTACAAATGCCATCTATGCGAATGCTCTTTTGCCGAGCGCCTGCAATGCCTGGAGCACATCAAGCAGGGGCATGCCCATgagtttgctttgctgctggccaaaggCGCCATCGAAACGGAAGCTATGGAAACGCCATTGAGTGCGGGCACCGGCAATGGCGGCGGCACTGCCTCCGATGACGAGGCTGGTGCGGCACGCGGCAAATATCCTGATTACAGCAATCGCAAGGTTATCTGCGCCTTCTGCGTGCGCCGCTTCTGGTCCACCGAGGATCTGCGTCGTCACATGCGTACACATTCCGGCGAACGGCCATTCCAGTGCGAGATTTGTCTGCGCAAATTCACGCTGAAGCACAGCATGCTGCGACACATGAAGAAGCACAGCGGACGCACGCACAATGGTGAGCCGATGGGCGGCTCCGATTGTTCCGATGATGAGCTGGCTGCCACACCACCAGCCAcacccatgcccatgcccacaAGTGCGgccgccagcaacaacaacaataacacttgccatacaaacaacaacaacaataacaacaacaacagcagcagtaaatTGGGTCTCCGTCTGCCCAAGCTGCACGAGCTGCTGGACAAGGCCAACGAATGGCGCGCCAGCCGGTTGGGTGAACACAAGGAGAACATAGGCGAGTCACCAGCGACACCCtcggcagccgcagcagcggcTGTAGCCAGTGGCGATCTGATTAGTAATCTGCTGGGCATCAGCGATCAGGGTATACTCAACAAGCTGCTCTCCTCGGCCGATGAGGCGGCCAAGCTACTCGGTGTGGACAAGTAa
Protein Sequence
MLATQQQQQQKQPNSTAHGDSEMERQRRESTTSESSLEHLDLGRTPKKLSSSSGAPQPTSTPHEATATATSTSASASASSSTTRKRKLRQQQQQLHLLSDEDESATELQQSQQQQHQQQQLEATSTAQRLRHKQRRNAAANASIVVDYGANDASSLRKKFRLNLNRSNASSGSAIAELSESGFVDGSAHSGYLLGNSSSSNANSTASANAPTSTKTLASGSSSSASGSGGSSPQGLCLSSAESGIGAGDEHMKYLCPICEVVSATPHEFTNHIRCHNYANGDTENFTCRICSKILSSASSLDRHVLVHTGERPFNCRYCHLTFTTNGNMHRHMRTHKQHQQSSSSTTAQGQQTHSHSQQQHQRRQQQNGGSGSNGNGGGPLAAPNRAESYESDASCSTDASSANSHSSCSQTNNNSHKTNNNNNTSQKNNDSLSKQRRPKTTINNNIIDDVDEEDDEEEEEEHAEDADVDDDVDSDADADGVADSHADVAVAKPLSITSTPDVATLLAGAGFPSEATSPVPSNQLISCPACVASDFDTLAALCRHLDAQHSDIPAKCRDCEVIFATHRQLQSHCCRGAMGHLPPMPPLGASSSPLHHEEDHDQDQQDRKHSIELDAETEVEKQREDFFYQLSLKGKTGSVSVSASPSPSPIKHEPADSKDLADIQSILNMTSSSCTSSFLRNFEQSVNTPCSSQYSLDGRDGEEEAQDAFTSEFRRMKLRGEFPCKLCAAVFPNLRALKGHNRVHLAAVGPSGPFRCNMCPYSICDKAALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHGKTSREEVKRAIVYHPAEDASCDDGKSSRLGDPSDLADISFRSNSPQPQPLLESSCSSSSQLKHMLMTEPIKQQQAPQQQPPLKIQVKSLDQLVDKPLSGAAATAMDLSMDALDLSKKPTAPATAQAAVGSPTAAATPVPELAAALEQQQFLLAQQQLAGDAASQYMQQLFRNLMFQLPPSVPFFNFMAPPAGPDKPPQLSPQPPRLPPMPVGMGVPMPAGGPVKMVIKNGVLMPKQKQRRYRTERPFACAHCSARFTLRSNMERHVKQQHPQFYAQRQRGGHHVMRGRGASSAAAAAAAAAAAAAAMGNHHHAGGHHHGGMGNAPISEQVKYAILAQQLTRKDTDLLHQALAHGSSSVASNPLLHFGYAAAGNGHVPGAVPVQSQAQSSVMDDDEPKLVIDEDEAEEIEDFDEVDEEDEDDDDELETMEAERERERVQAKPAVEQLPQSTEVARKVADTILEQAIKAGKSSPHPSPTPVQAPPSRNATPKPPEATPPPPHTMKTMIAQVESVAKSLKDVASSPFKDESVDLVPVAKLVDNATSSQMSLSFNSYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTSSSSGGSGNEPKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPAEDVNEPIPVPKSVEEIELEEQRRRRKEQAEQEERLERERRAQQERERERERERERERERERERERERERDQLLQQLAAAAQLTQQMNAAAAAAASSGNTNNAAETNGGDLPYKCHLCECSFAERLQCLEHIKQGHAHEFALLLAKGAIETEAMETPLSAGTGNGGGTASDDEAGAARGKYPDYSNRKVICAFCVRRFWSTEDLRRHMRTHSGERPFQCEICLRKFTLKHSMLRHMKKHSGRTHNGEPMGGSDCSDDELAATPPATPMPMPTSAAASNNNNNTCHTNNNNNNNNNSSSKLGLRLPKLHELLDKANEWRASRLGEHKENIGESPATPSAAAAAAVASGDLISNLLGISDQGILNKLLSSADEAAKLLGVDK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00359670;
90% Identity
-
80% Identity
-