Hdun005981.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Hirtodrosophila duncani
Gene Symbol
ftz-f1
Assembly
GCA_037043425.1
Location
JBAMBM010000194.1:6423922-6438784[+]

Transcription Factor Domain

TF Family
SF-like
Domain
zf-C4|SF-like
PFAM
AnimalTFDB
TF Group
Zinc-Coordinating Group
Description
The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 3 0.015 1.5e+02 1.7 9.7 55 132 69 145 19 169 0.60
2 3 1.8e-19 1.8e-15 57.4 0.4 1 79 315 392 315 412 0.74
3 3 8.5e-71 8.5e-67 226.5 2.3 155 408 525 771 511 773 0.93

Sequence Information

Coding Sequence
ATGTTATTAGAAATGGATCCACAACAGGCGACAGTGCAATTTATTTCATCGCTGAATATGTCGCCTTTTAGTatgcagctggagcagcagcccTCAAGTCCTGCCTTGGCAGGTAgcaatcaacagcagcagggtggcagcaacagcaacaacaacaataataacagcagcaatgaGAATGACAATTTGAGCAATGCCGATAATGATTATAGCGGCTATACGCTGCAATTGACGgcacaccagcaacagcagcagcagcaacagcatcaccatcagcaacatcaacaacagcaacagcagcagcattaccaacagcaacagaataTTGCCAATGTGAATGcgaatcaacagcaatttaATGCCGCCTCCTATtcgtatatatacaatttcgattcccaatatatatttcctaCAGGCTATCAGGACACAACCTCCTCACATTCCCAGCAGAGTGGTGGTggaggcggtggcggtggcaactCGGCCTCAAATCTGCTTAATGGCAGCAGCTCCGGGGGCAGTTCtgctggtggcggcggtggctaTATGCTGCTCCAAGCCTCAGCCAGATCTAGTGTGGGCAGCGGCAATGTCAACCACATGGGTGGCACTGCTAGTGCTGTTGGCTCTGGCACTGGTGCAGTTGGCGGCAATGCGCATGGACATGGCGGAACTAGTGCTTCGTCGGGCATGACTGGCGAAGGCATTGACTTTAAGCATCTCTTCGAAGAATTGTGCCCTGTGTGCGGTGATAAAGTCTCAGGCTATCATTATGGTCTGCTGACCTGCGAATCCTGCAAGGGCTTCTTCAAGCGCACGGTACAAAATAAGAAGGTCTACACCTGCGTGGCTGAACGATCCTGTCACATTGATAAGACGCAAAGGAAAAGATGTCCCTACTGTCGTTTCCAGAAATGTCTTGAGGTTGGCATGAAATTGGAGGctGTACGGGCGGACCGCATGCGTGGTGGACGCAATAAGTTTGGACCCATGTACAAACGAGATCGGGCGCGAAAGCTGCAAGTAATGCGCCAGCGTCAGTTGGCGTTGCAGGCGCTGAGTAATTCCATCGGCCCGGATATAAAGCCCACGCCGCTCTCACCGGGCTATCAACAAGCATATccaaatatgaatattaagCAAGAAATTCAAATACCTCAGGTATCCTCACTTACGCAATCGCCGGACTCATCACCCAGCCCGATAGCCATTGCTTTGGGTCAGGTGAATGCCAGTGCGGGCGGCGGTGTGATAGCCACGCCTATGAACGCTGGCAATGGTGGTGGAGGCGGCTCTGGGGGcggcagtggcaatggcaacctCAACTCCTTGGGCAGTGGCAATacccacaacagcagcaacaacagcaatatggCTGGCAACAGTGGTGGTGGATCAGGCTCAGGAGGTggcggaggaggaggtggtggtggcaccaatgcaggcggcggcggaggCAGTAGCTCAGATGGCCTGCAACGTAATAATGGAGGCGGCAATGGTGGCCATGAAACAGGCTCTGGATCTCTTCAACATACAGCCGATTCGAAATTGTGCTTTGATTCTGGCACACATCCATCGAGTACAGCCGATTCGGTTATTGAGCCATTAAGAGTCTCGCCAATGATACGTGAATTTGTACAATCGATAGATGATCGGGAATGGCAAACGCaattatttgctttgctgcaaaagcaaacctacaatcaagtggaagtggatcTCTTTGAGCTAATGTGCAAAGTGCTCGATCAGAATTTATTCTCGCAAGTCGATTGGGCAAGAAACACCGTCTTTTTTAAGGATTTGAAGGTGGATGATCAAATGAAGCTATTGCAACACTCCTGGTCGGATATGTTAGTGCTGGATCATCTCCATCATCGTATACATAATGGTCTGCCCGATGAAACGCAACTGAATAATGGTCAAGTCTTCAACTTGTTGAGCCTTGGTCTACTGGGTGTGCCTCTACTTGCGGATTATTTCAATGAGCTGCAAAATAAGTTGCAGGATCTGAAGTTCGATATGGGCGATTATGTGTGCATGAAATTCCTAATATTGTTAAATCCAAATGTCCGTGGGATTGTGAACAGGAAGACGGTTTCGGAGGGACACGATAATGTACAGGCCGCCTTGTTGGACTACACATTGACATGTTATCCCTCAGTTAATGAAAAATTCAGCCGACTTGTGAACATACTGCCCGAAATCCATGCAATGGCCGCTCGCGGAGAGGAGCACTTGTATTCCAAACACTGCGCTGGCAGTGCGCCCACACAGACGCTGCTGATGGAAATGTTGCATGCCAAACGAAAGGTGTAA
Protein Sequence
MLLEMDPQQATVQFISSLNMSPFSMQLEQQPSSPALAGSNQQQQGGSNSNNNNNNSSNENDNLSNADNDYSGYTLQLTAHQQQQQQQQHHHQQHQQQQQQQHYQQQQNIANVNANQQQFNAASYSYIYNFDSQYIFPTGYQDTTSSHSQQSGGGGGGGGNSASNLLNGSSSGGSSAGGGGGYMLLQASARSSVGSGNVNHMGGTASAVGSGTGAVGGNAHGHGGTSASSGMTGEGIDFKHLFEELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNKKVYTCVAERSCHIDKTQRKRCPYCRFQKCLEVGMKLEAVRADRMRGGRNKFGPMYKRDRARKLQVMRQRQLALQALSNSIGPDIKPTPLSPGYQQAYPNMNIKQEIQIPQVSSLTQSPDSSPSPIAIALGQVNASAGGGVIATPMNAGNGGGGGSGGGSGNGNLNSLGSGNTHNSSNNSNMAGNSGGGSGSGGGGGGGGGGTNAGGGGGSSSDGLQRNNGGGNGGHETGSGSLQHTADSKLCFDSGTHPSSTADSVIEPLRVSPMIREFVQSIDDREWQTQLFALLQKQTYNQVEVDLFELMCKVLDQNLFSQVDWARNTVFFKDLKVDDQMKLLQHSWSDMLVLDHLHHRIHNGLPDETQLNNGQVFNLLSLGLLGVPLLADYFNELQNKLQDLKFDMGDYVCMKFLILLNPNVRGIVNRKTVSEGHDNVQAALLDYTLTCYPSVNEKFSRLVNILPEIHAMAARGEEHLYSKHCAGSAPTQTLLMEMLHAKRKV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00804449;
90% Identity
iTF_00804449;
80% Identity
iTF_00804449;