Basic Information

Insect: Hirtodrosophila confusa
Gene Symbol: erm
Assembly: GCA_035043065.1
Location: JAWNNI010000038.1:2140731-2142596[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 1.9e-05 0.0015 19.3 0.8 1 20 323 342 323 345 0.93

2 6 9.6e-07 7.9e-05 23.4 1.6 1 23 351 373 351 373 0.97

3 6 7.5e-07 6.2e-05 23.7 2.5 1 23 379 401 379 401 0.98

4 6 8.9e-06 0.00073 20.3 3.2 1 23 407 429 407 429 0.98

5 6 0.0011 0.088 13.8 6.0 1 23 435 457 435 457 0.99

6 6 1.7e-05 0.0014 19.4 4.3 1 23 463 486 463 486 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	1.9e-05	0.0015	19.3	0.8	1	20	323	342	323	345	0.93
2	6	9.6e-07	7.9e-05	23.4	1.6	1	23	351	373	351	373	0.97
3	6	7.5e-07	6.2e-05	23.7	2.5	1	23	379	401	379	401	0.98
4	6	8.9e-06	0.00073	20.3	3.2	1	23	407	429	407	429	0.98
5	6	0.0011	0.088	13.8	6.0	1	23	435	457	435	457	0.99
6	6	1.7e-05	0.0014	19.4	4.3	1	23	463	486	463	486	0.98

Sequence Information

Coding Sequence: ATGCAACCGTGTAGTCCATCGGGTGTTATTGCAATGATGCCGCCATCGAAGAGTCCCATCATGGAAACAGCCGCCAGCGAGAGCAATCAGCCATCGAGCACCACAGCCAGCAGCGACGCCAAGCGCTCCTGCCCGTTGAAGTTCTCCATTGCCAAGATCATGGAGCCAGATCACAAGCAGGCGGCGCCATCCACCATATCCAGCCCGCAGGAGCAGCCGCTGCAGGAGGAGGAGCACTTGCATTCAGACATCTATGCCGACTCGGAGCGCTCCTGCAGTCCCATCGAGGTCACTGGCGATGAGGAGCCGGCGGTCAACTACGACTCGGCCTTTAAGAAGTATGTGCCCGGTTCCTCGGGTTCCTCcgcggcagcaacagctgctgccacagctgcCGCCGCAGCTTCCGCTTCTGCCTCGGCCTCGGCCAGCGCGGTGCAACAGTTTGTGAGCACGCGGCATCAGGAGCTGCTCTCGCAGTATCCTTTGCTCTACTATGCGCCCAATCAGCTGATGTgcgccgctgctgcggctCAGTACGCAGCGCTGACCGCGCAGCAGCAGACGCTGGCCAACGCTGCGCATCTGAGCAGCTTCACGGCCTCGTTGAATGCCACGCTGCATCACTCGCAGTCGCTGCGCCGCAATTTGGGGCATCCGTTGGCGGCAGCGGCCGCCGCTGCGGCCGCAGTGGCGCAACAGCAGACGCCGacgctgcagcagcaccagcagcagagTCTGGAGAAGTCGCCCATACGGACGCCACATGCCGCACAGCACGCGAGCTTGAAGCGCAAGCGTTCGCCGCAGTTGGAGCTGACGACGCCGCCATTGGcaatgccgctgctgccaccgGCGGTGGCAACATCTGCGCACTTAAGTGTGGCACGTTCGCGCTCACCGTCGCCGCATGGCTCAATGGAGGACAGCAGCCCCGGCTCGGCCAATGGGGGCAAGCCGAAGACGTTCTCCTGCCTGGAGTGTGGCAAGGTCTTCAATGCGCACTACAATCTGACGCGCCACATGCCGGTGCACACCGGCGCCCGTCCGTTTGTGTGCAAGGTGTGCGGCAAGGGGTTCAGGCAGGCCTCCACCCTGTGTCGCCACAAGATCATACACACCTCGGAGAAGCCGCACAAGTGCCAGACCTGTGGCAAGGCCTTCAATCGCAGCTCGACGCTGAACACCCACGCCAGGATACACGCCGGCTACAAGCCCTTTGTGTGTGAGTACTGCGGCAAGGGCTTTCACCAGAAGGGCAACTACAAGAACCATAAACTGACCCACAGCGGCGAGAAGGCCTACAAGTGCAACATCTGCAACAAGGCCTTCCATCAGATCTATAATCTGACCTTCCACATGCACACGCACAATGATAAAAAGCCCTACACTTGCCGCGTGTGCGCCAAGGGATTCTGCCGCAACTTTGATCTGAAGAAGCATATGCGCAAGCTGCATGAGCTGGGCGGCGAGGGGCTGGACGATGATCTGCCCCCGGCCTATGAGCGGCGACGTGAGTACACCAGAAGGGAGCCGTTGTCCAACTACGGCCAGGTCAGCCCCAGCCAGCTGACGCCAGACTCCTCCTCCGGCAGCCTGTCGCCGCCTATTAATGTGACCACGCCCCCGCTGTCCAGCGGCGAGGCAAGCAACTCGGCCTGGACGCGTACGCCCTATCCGGAGACAGCAGCTGTTGCACCGCCAGGACACTTTCATCACTTGCAGGCGCCGCCGGCGGGCTTGCATGGCGATTATGCAGGCAACTCGTCCTTTTTGCATcccgcacagcagcagcagcatccgcAGCACCGTCtgtccgctgctgctgccctgGAGAATGTGCCCTTCATAGCCAAGGTCTTTTGA
Protein Sequence: MQPCSPSGVIAMMPPSKSPIMETAASESNQPSSTTASSDAKRSCPLKFSIAKIMEPDHKQAAPSTISSPQEQPLQEEEHLHSDIYADSERSCSPIEVTGDEEPAVNYDSAFKKYVPGSSGSSAAATAAATAAAAASASASASASAVQQFVSTRHQELLSQYPLLYYAPNQLMCAAAAAQYAALTAQQQTLANAAHLSSFTASLNATLHHSQSLRRNLGHPLAAAAAAAAAVAQQQTPTLQQHQQQSLEKSPIRTPHAAQHASLKRKRSPQLELTTPPLAMPLLPPAVATSAHLSVARSRSPSPHGSMEDSSPGSANGGKPKTFSCLECGKVFNAHYNLTRHMPVHTGARPFVCKVCGKGFRQASTLCRHKIIHTSEKPHKCQTCGKAFNRSSTLNTHARIHAGYKPFVCEYCGKGFHQKGNYKNHKLTHSGEKAYKCNICNKAFHQIYNLTFHMHTHNDKKPYTCRVCAKGFCRNFDLKKHMRKLHELGGEGLDDDLPPAYERRREYTRREPLSNYGQVSPSQLTPDSSSGSLSPPINVTTPPLSSGEASNSAWTRTPYPETAAVAPPGHFHHLQAPPAGLHGDYAGNSSFLHPAQQQQHPQHRLSAAAALENVPFIAKVF

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00579469;
90% Identity: iTF_00803059;
80% Identity: -