Basic Information

Insect: Drosophila pruinosa
Gene Symbol: erm
Assembly: GCA_018150935.1
Location: JAECWR010000023.1:2675763-2679146[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 1.4e-05 0.0011 19.3 0.8 1 20 314 333 314 336 0.93

2 6 7e-07 5.7e-05 23.4 1.6 1 23 342 364 342 364 0.97

3 6 5.5e-07 4.5e-05 23.7 2.5 1 23 370 392 370 392 0.98

4 6 6.5e-06 0.00053 20.3 3.2 1 23 398 420 398 420 0.98

5 6 0.00078 0.064 13.8 6.0 1 23 426 448 426 448 0.99

6 6 8.8e-06 0.00072 19.9 7.5 1 23 454 477 454 477 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	1.4e-05	0.0011	19.3	0.8	1	20	314	333	314	336	0.93
2	6	7e-07	5.7e-05	23.4	1.6	1	23	342	364	342	364	0.97
3	6	5.5e-07	4.5e-05	23.7	2.5	1	23	370	392	370	392	0.98
4	6	6.5e-06	0.00053	20.3	3.2	1	23	398	420	398	420	0.98
5	6	0.00078	0.064	13.8	6.0	1	23	426	448	426	448	0.99
6	6	8.8e-06	0.00072	19.9	7.5	1	23	454	477	454	477	0.98

Sequence Information

Coding Sequence: ATGGTTTACTTTAGTCCGCGTGGCATGCAACCGTGTAGTCCATCGGGTGTAATTGCAATGATGCCGCCATCGAAGAGTCCCATCATGGAAACCGCCGCCAGCGACAGCAATCAGACCAACAGCACTGCCAGCAGTGACACCAAGCGTTCCTGCCCTTTGAAGTTCTCCATTGCCAAGATCATGGAGCCGGATCACAAGCAGCCGACGCCGCATACACTTCCTCAGCTCCCGCAGCAGCCGGAGCCAGAGGAGGAGCAGCCATATGCCGACTCGGAGCGCTCTTGTAGCCCCATTGAGGTGACTGGCGACGACGAGGAGCCCGCTGCCGTCAACTACGATTCGGCATTTAAGAAATATGTGCCAGGCTCTAGTCTGGCTGCCACCGCTGCAGTTTCAGCTACAGCTTCGGCCGCCTCCTCTTCCGCCTCCGCCTCCGTTGTGCAGCAATTTGTGAGCACGCGTCACCAGGAGCTGCTCTCGCAGTATCCTCTGCTCTACTATGCGCCCAATCAGCTGATGTGCGCCGCTGCTGCTGCCCAGTATGCGGCACTCACAGCTCAACAGCAGACACTGGCCAGTGCTGCACATCTGAGCAGCTTCACTGCCTCCTTGAATGCCACGTTGCATCACTCGCAGTCGCTGCGCCGCAACTTGGGGCATCCGTTGGCTGCCGCGGCCGCTGCTGCCGCCGTCGCACAATCCCAGCAAGCGCCGCCGCTGCAGCAGTCGCTGGAGAAGTCGCCGGCACGCGCCGCACAGCAGACGCCAGCCAGTCTCAATCTCAATCTTAATCTGAAGCGCAAGCGTTCGCCACAAACGGAGCAAAGGACGCCGCCCTTGGCCCAGGCATTGCCACGTTCTCGCTCCCGCTCCCCTTCGCCGCATGGCTCGCTGGAGGACAGCAGTCCCGGCTCCGCCAATGGCGGCAAGCCCAAGACTTTCTCCTGCCTGGAGTGCGGCAAGGTGTTCAATGCACACTACAATCTGACCAGGCACATGCCCGTGCACACGGGTGCTCGTCCCTTTGTGTGCAAGGTGTGCGGCAAGGGCTTTCGCCAGGCATCGACGCTCTGCCGGCACAAGATCATACACACCTCGGAGAAGCCGCACAAGTGCCAGACCTGTGGCAAGGCCTTCAATCGCAGCTCCACGCTCAATACGCATGCCAGGATTCATGCCGGCTACAAGCCGTTTGTGTGCGAGTATTGTGGCAAGGGTTTCCATCAGAAGGGCAACTACAAGAACCATAAGCTCACCCATAGCGGGGAGAAGGCGTACAAGTGCAACATCTGCAACAAGGCCTTCCATCAGATCTACAATCTCACCTTTCACATGCACACACACAACGACAAAAAGCCGTATACGTGTCGTGTGTGCCACAAGGGCTTTTGCCGCAATTTTGACCTGAAGAAGCACATGCGAAAGCTGCACGAGATTGGCGGCGATTGTCTGGACGATGATCTGCCGCCGGCCTATGAGCGTCGTAGAGAGTATACCAGACGGGAACCGCTCTCCAGCTACAGCCAGGCGAGTCAGCTGACGCCGGACAGCTCCTCGGGCAGTCTGTCGCCACCGATAAATGTGACCACGCCGCCTTTGTCCAGCGGCGAGGCCAGCAATCCCGCCTGGTCCCGCACACCCTACCAGGAGTCGACTCCGGCTGCGCCTGGCTCACATTTCCATCATCATTTGCCGGTGCCGCCGACTGGACTGCATGGCGATTACCCGGGCAGCTCTCCCTTCCTGCAGCTGCCACATCCCGCTCAGTCGCATCCCCAGCAACAACAGCGACTCTCGGCTGCTGCGCTGGAGAATGTGCCGTTCATAGCCAAAGTGTTTTGA
Protein Sequence: MVYFSPRGMQPCSPSGVIAMMPPSKSPIMETAASDSNQTNSTASSDTKRSCPLKFSIAKIMEPDHKQPTPHTLPQLPQQPEPEEEQPYADSERSCSPIEVTGDDEEPAAVNYDSAFKKYVPGSSLAATAAVSATASAASSSASASVVQQFVSTRHQELLSQYPLLYYAPNQLMCAAAAAQYAALTAQQQTLASAAHLSSFTASLNATLHHSQSLRRNLGHPLAAAAAAAAVAQSQQAPPLQQSLEKSPARAAQQTPASLNLNLNLKRKRSPQTEQRTPPLAQALPRSRSRSPSPHGSLEDSSPGSANGGKPKTFSCLECGKVFNAHYNLTRHMPVHTGARPFVCKVCGKGFRQASTLCRHKIIHTSEKPHKCQTCGKAFNRSSTLNTHARIHAGYKPFVCEYCGKGFHQKGNYKNHKLTHSGEKAYKCNICNKAFHQIYNLTFHMHTHNDKKPYTCRVCHKGFCRNFDLKKHMRKLHEIGGDCLDDDLPPAYERRREYTRREPLSSYSQASQLTPDSSSGSLSPPINVTTPPLSSGEASNPAWSRTPYQESTPAAPGSHFHHHLPVPPTGLHGDYPGSSPFLQLPHPAQSHPQQQQRLSAAALENVPFIAKVF

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00519384; iTF_00471073; iTF_00553896; iTF_00803059; iTF_00805403; iTF_00803821; iTF_00472543;
90% Identity: -
80% Identity: -