Hcon009005.1
Basic Information
- Insect
- Hirtodrosophila confusa
- Gene Symbol
- -
- Assembly
- GCA_035043065.1
- Location
- JAWNNI010000148.1:4537176-4538544[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 11 4.3e-06 0.00035 21.3 0.9 2 23 12 33 12 33 0.95 2 11 8.2e-06 0.00067 20.4 1.7 1 23 39 62 39 62 0.98 3 11 6.1e-06 0.0005 20.8 1.3 1 23 134 156 134 156 0.98 4 11 6.2e-06 0.00051 20.8 1.5 1 23 162 185 162 185 0.98 5 11 0.012 0.99 10.4 2.6 1 23 191 214 191 215 0.93 6 11 0.00015 0.012 16.5 0.5 1 21 219 239 219 240 0.95 7 11 0.033 2.7 9.1 5.0 1 23 263 285 263 285 0.97 8 11 6.9e-06 0.00056 20.7 1.3 1 23 298 320 298 320 0.97 9 11 1.3e-05 0.0011 19.8 3.3 1 23 326 348 322 348 0.97 10 11 2.9e-06 0.00024 21.8 0.5 2 23 356 377 355 377 0.96 11 11 0.0011 0.091 13.7 0.7 1 22 383 404 383 407 0.92
Sequence Information
- Coding Sequence
- ATGACAGATAATGCgttaattaaaaaagcaaATGTTTGTGAAAGATGCGGCAAGTGTTTTTCAAAACCTGCTCTACTGCGTCGCCATCTGGTTGTGCATGGCACTGAAAAACCGTACTCATGTGACAGGTGCTCCAGTCAGTTCTCCCAGCAAAGCTCACTACAACGTCACATACGCATAAAGCACACTGTGCCCGTGGAGAGCGACGACTCCGAGGTGGCACAACATGCGCTAGCAGCCTTAAAGCAGCTACAAGCCAGCCACAGGCACACCACAGTTACTAGTATACCCGGACAGGCCACACTTGAGGAGCAGCCTCCTTGCCAAATGGTTAAGATAGTGGACAAACTGCATCCAAATAGGAAGCTGCTGCAGCGACAGAAACAAAATAGATGCTACTTTGTGTGTGAATACTGCGCCAAGGAGTTTAGCAAGACCTACGATCTCATAAGGCATCGTCGCTCTCACACCAAGGAGACACCTTATCCATGCAATCGTTGTCTCAAGCGTTTTGCCACACAGTCCAAGTTAAATGAGCATCAAAGGCGCCTGCATACCAAGCTGAAGAATCACACTTGCAGCGTTTGCAGCGCCCGATACAGCTACAAAGGCGAGCTGGACAAGCATCTGTCTGAGCAGCACCACGATTTAACTTACAATTGCGCGCACTGTAGCCGTAGTTTCATTTCGAAAGCTGCCTGGCAGAAACATCAGAAGGTTGAAGCCGATCCGCAGTTGTTCAAGCTAATACAACTGTTGCCACAGCCGGTTATGTCACAGCGTACCTACAAGTGTATATACTGTGCGAAGAAGTTTAATCGCAAATACAACTGTCGCATTCATATGGTGACACATTTAAGGCGATTGCTAAGTGAGCAGCCTGCCCAGCGCCACAGCTGCCTGCAATGTGGCAAGAACTTTCAAAAACCCAGCGATCTGGCGCGTCATCTATTAACGCATTCCCAGCTCAAGCAACACATTTGTCAGGTGTGCCAAAAGCGCTTCACCCTGAAGTCAACGTTGTCCAGACACTTGCAGACGCATCAACCGGAACGTAAGCCAATCAGTTGCCAGGTTTGCGGCAAGTCCTATGCCTCCAAAACATCGCTGAAACTTCATCTTCGTTTGCACACTGGCGAACGACCATTTAGTTGCGAAGTTTGCGCTGAAACTTTCCGCACCTCCGGGCACAGGCTAGAGCATATGCGCGCTGAACGGCACAGGAATGACGCCTCCAATGCACTCATCTTATGA
- Protein Sequence
- MTDNALIKKANVCERCGKCFSKPALLRRHLVVHGTEKPYSCDRCSSQFSQQSSLQRHIRIKHTVPVESDDSEVAQHALAALKQLQASHRHTTVTSIPGQATLEEQPPCQMVKIVDKLHPNRKLLQRQKQNRCYFVCEYCAKEFSKTYDLIRHRRSHTKETPYPCNRCLKRFATQSKLNEHQRRLHTKLKNHTCSVCSARYSYKGELDKHLSEQHHDLTYNCAHCSRSFISKAAWQKHQKVEADPQLFKLIQLLPQPVMSQRTYKCIYCAKKFNRKYNCRIHMVTHLRRLLSEQPAQRHSCLQCGKNFQKPSDLARHLLTHSQLKQHICQVCQKRFTLKSTLSRHLQTHQPERKPISCQVCGKSYASKTSLKLHLRLHTGERPFSCEVCAETFRTSGHRLEHMRAERHRNDASNALIL
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00805343;
- 90% Identity
- iTF_00805343;
- 80% Identity
- -