Hcon002043.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Hirtodrosophila confusa
Gene Symbol
-
Assembly
GCA_035043065.1
Location
JAWNNI010000028.1:161486-166116[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 26 0.0012 0.1 13.6 0.8 1 23 212 234 212 234 0.96
2 26 0.054 4.4 8.4 1.4 1 23 240 262 240 262 0.98
3 26 0.033 2.7 9.1 0.4 2 23 294 315 293 315 0.95
4 26 0.067 5.5 8.1 3.1 1 23 392 415 392 415 0.93
5 26 0.56 46 5.2 1.8 2 23 426 449 425 449 0.93
6 26 2.3 1.9e+02 3.3 0.9 1 20 455 474 455 476 0.91
7 26 1.1 89 4.3 1.1 1 23 496 518 496 518 0.97
8 26 0.0056 0.46 11.5 0.2 1 23 597 620 597 620 0.97
9 26 0.056 4.6 8.4 0.1 3 22 631 650 629 650 0.93
10 26 0.027 2.2 9.4 2.0 1 23 659 682 659 682 0.96
11 26 0.0016 0.13 13.2 0.4 2 23 710 731 709 731 0.97
12 26 0.00043 0.035 15.0 8.1 1 23 739 761 739 761 0.99
13 26 0.15 13 7.0 0.9 3 23 914 935 912 935 0.93
14 26 0.0024 0.2 12.6 0.6 2 22 943 963 942 963 0.95
15 26 0.16 13 6.9 0.4 1 23 972 995 972 995 0.89
16 26 1.2e-05 0.001 19.8 1.9 1 23 1020 1042 1020 1042 0.97
17 26 0.00016 0.013 16.4 0.9 1 23 1049 1071 1049 1071 0.98
18 26 0.054 4.5 8.4 0.0 2 21 1098 1117 1097 1118 0.93
19 26 0.013 1.1 10.4 4.7 1 23 1163 1186 1163 1186 0.96
20 26 0.0061 0.5 11.4 0.4 1 23 1223 1246 1223 1246 0.96
21 26 0.0011 0.092 13.7 3.5 1 23 1269 1292 1269 1292 0.97
22 26 1.6e-05 0.0013 19.5 0.1 2 23 1319 1340 1318 1340 0.95
23 26 5.4e-05 0.0044 17.9 2.9 1 23 1346 1368 1346 1368 0.99
24 26 4.4e-06 0.00036 21.3 2.0 1 23 1374 1396 1374 1396 0.97
25 26 6.7e-08 5.5e-06 27.0 2.4 1 23 1402 1424 1402 1424 0.99
26 26 0.0024 0.2 12.7 1.8 1 21 1430 1450 1430 1454 0.91

Sequence Information

Coding Sequence
ATGCTGCCGACTGATCTTTGTCGCACGTGTGCGCAACAGGATGACAACATGTTGGCGCTCTCAACGCGTTCCGAAATCTACGCAAACAAAAGTTTCTGCGACATATTGCACGAATTAACGCGAATTGATTCACTGCTGGAACCCCCAGATGATAAACTACCGCAGTATTTGTGCGGCGACTGCCTGGGCAAGCTGGAAGATGCCTACGTTTTTGTGTTACAGGCGCGCCAGGTGCAAGAGCAATTGTGCAGGCTAAGCAAAGGTTTACAATGCTTGGACGAGACGCCCATAGAcataaaaacagaaacagacatCGTCTTGGACGCTGATCCAAATGGGACATCTCAAAATGCGGCGCCATTGGATGACGACGGTACTGAGGTTACTACTGTGTATGCAGCTGCCTTAAAGTGGCAGCCAGCGAGCGGCAGCGAAAGCGGCCAGGTGGATGACGATGAcgaTGATGTGGATTTCAAGCCCACGCAGCTGCGGCGTAGTGCACGTCAGGCCAAACTTGCCTCAGACAGCGAAGATGAAGCCACTTCTGGCAAAGTGAAGCCAGTGCCGGTCAAGCGACGTCGCGGTCGTCCAGCGCGATTGGCCAAAAAAGCATCTATAAACGAGGACGGACGTCATGCGTGTGAGGTGTGCGGCAAAACGTTTTCATGGTATCGTGACATGCAGCGTCATGCTCGCATACACTTCGAGCAGGCGGCGTACGTGTGTGACAGCTGCGGCAAAGGATTCCTCCGCAAGGATAAGTACATGTTCCATCTGCGCACACACGAGAAGCGGGATGCCAAATCGCAGGCACTGCAAATGAGCAACGAATGGCGATTTGCCGAACGCCTCTATAGCTCCGGTCGTCTTAAGCGCCTCGAGTGTAAGCTTTGCGGCTTGAAGTGTCCACGCATACAGGAGCTGCGTGAGCATGTTGCGAGCCATGTCACCATTGAATCATTATCCACGCTCCGCATGGACAGCGATGTTATCAGTGAGCAGTTTGGCAGTCGGCAAGTGCAACTGGACTTGGCGCAAATTAAGCAACAGGTGTGCGTAGAGATAGCCAAGGGACGGGAGTATCTGGACAAATACTGTGCTGTGGTCAATGCAAATGGCTATGAGCTGTGTCTCAGCGACTCGGACGAAGACCTAGCTGGCTTGACGCCTCCATATCAATGCCTGCCCTGCAATACTTTCTTTACACGCAAACATCGACTGATGCGGCACACGCTTGAGGAGCACACACAAACGGCAAAAGAGACTCCTTGGCAACGCTGTAACGTTTGTCAGATTGGATTTCTGAACGTGAAGCTTCTGGAGCAGCATCAGCGCACCCAGTGCCACAGCCAACTGAAGCGCTATAGCTGCACCAAATGCCCAGGAAAGTTTATTTGGCTACAGAATCTCAAGCAGCATGCTTGCTCCCAGAGCACGATGAAGCAGGAGgatgaggagcagcagcaggtcaATGAAAGCCGTCAGTTCCAGTGCTGCCTGTGCGATGCTCAGCTGCAGAGCATGACAACCCTGCGTGACCATTTACTGATTCATCGCGATGGACGCAGCGGCATCGATCCAGATCACCGGGCTGCCTTCTTCCGTTGCCATTACCCAGATGGTCTTGATTGCAGCCTTACAGAGCTGGGCACGCGCATTGCCTGCGACTTTGTGGCGCAGGATTATGGACGCTATTTTAATGCCTGCAAAAGCAACGGCCAAGAGCTAGATTTCTTCGACTCGGACACAGATTTGAGCGATGTGGAGCAGTCGGCGTCGTCAGCTCTGTATACGTGTGATTTGTGTGGTGAGATCATCATGCGGCTTACCAACCTTCTTCAGCATCAACAGAGTCAACATAATGAGCTGGATGACACATTGCCTCATTTGTGCAATGATTGTGGACTCGGTTTTGTGGCTGAGCCACTGCTCCGACAGCATCGCCGACGCGTGTGTGCCAAGCAGCATGCCAAATATCATTGCCAGCGTTGCAAGCTTCCCTTTATCTGGCAGTCCAACTACGAGCGGCATATGCAGCAGGAGCACGAGGTGGAGCCTGAAGATGATCATGATCAGGTGTCCAGCATCAATCTGAGAAGCAAACGACAGCCAACATCTGTCAAGCTGCAGTGCGACGAGTGCGAAAAGGTCTTTATCTGGACAAAGGATTTGACGCGCCACAAGCGCATCCATCAGCCGCAGACGTCGGCGCAGTACGAGTGTTGTCACTGCGAACGCAAGTTTCATCGCAAGGATGGCCTTAAGTCGCATATGCGAGTGCACGGCGAGCAGCAGCTGGACGAGTTGGCGGCTGCAGCCATCAGTGATCAACCAGCGACGGTGCTACAGCGCACGCCCTTGGTGTTGACGCAACTGTGCAGGCCCAATGGCTGCAAGCAAATCCAGTGCATGATCTGTCTCTCCCAACACACAAAGATCTCTGATCTGCGAACGCATTTGCTGACACATCAGTTTGTGGTGAGGTTTGCCGAGGAGCGTGCCAAGCCGGAAAGCATTGCCAGCATTAGCCGTGCATTATATCCGGAGCTGGGTACACCTCTGAATAAGCAACCATTGATCGAGCGCATCCAGAGCGATGTGGCCAAGGGCGTTGAGTTGGAAAGATTCATTTCCATTACCAACGAGGCGGGTATTGAGCTGAGTCTAGACAGCAGCGAAACTGATACGGATTCAGACTCAGCCGATACGGAAAGAAGCAGCAATGGACGACTGTACGGCTGTGTTCTGTGTCAGCTGAAGGTGTCGCGCAAGCATCAGCTCTATGCCCATCAGCTGGAGCAGCATGCGTGGCAACGGGCCACCTGGGTTTGTTCCCACTGCCAGGCTACATTCGTCAATGAACAGCTGCTGGAGCATCATTATCGTACGCTCTGCCGCAATGGCCAGAAGCGTTTTCTCTGCCGCAAATGTCCATTGCGCTTTCGTTGGCGCGACAATCTGAAGCTGCACACAGGCGTCGCACATCAGGAAGCAACTGTAGAACAGACGAATGCAGGCATTCCAATGAATGGGGCTCGATTGCTGCCCGTTGTCAGTTACGACTGCACCGAATGCAATCGCAGcttcaaaatgcaaaaggaTCTCACGCGACATACGCTGATGCACTCACAGGAGGCAAACATTTATCGGTGTCGTTGGTGTGCGCGACGCTTCTACCGCCAGGCCAATCTGCTGCAGCACATTGAGCGTCATGGCATCAGCGCCGCCCAGCTGCCGTATGCTGAGGCTCTGCTTAATGCCAGCCGACATCCGCATGGCCAGAAGTGCATCCAGTGTAAGGTGTGCGATGTGCGTTATCCCACCATTGCCGCATTGCGTTCCCATCTTCTGTCCACGTCGGCGGGCACGCATCATGACATTGGCTCCATGCTCAACTACTCGATTACCAATCAGCTAGGTTACGAGCTGCACCTGGATGACTCTGAAACAGATGAGGAGATCAAACCACCGGGCATACCCCCGCACTATACCTGCAGCATGTGCCAGCTGCGTTGTGTGCGTAAATATGAGCtacatcagcatcagcaggcCATGCACCGACTGGAACGCATTGGCGAAGGCTGTGATCAGTGCATCTTTAAGAGTGTCTCGTCGGATCTCATTGCGTATCACCAGCGCGTGCTGTGTGGCAACACAGAGAAACAGTTCAAGTGCGTCAAGTGTGGTTACATGTTCATGTGGGAGTCAAATCTGTTACTGCACATGCAGCTGCAACATCCGAGCAATGACGGGCAGGACGAGCCGGCCTCTATGCCGAATGTGCCTAGTGTTGACTGCCAGATCTTTCAATGTGGTCAGTGCCCGCGTAAATACAATCGAAAGGATCGACTGACGGCGCATGTGAAGAAGTGTCATACACCAGGCGCAACGGGATCAACTGTGACCCCAACAAAAACCACAACGTCATCCGCTGCCAAGCAGCAAAAGAGTTTTCTCTGCGCCTTCTGCGGCAAGGCGGTGAGCTCGTCCTCAAATCTCATTATACATATACGCCGCCATACCGGCGAGAAGCCATTCAAGTGCGACTATTGCGATATGGCTTTTCCACGCTCCTCCGATCTCCAGTGCCATCGTCGCACTCACACGGGTGAGCGGCCACATATCTGCACCGTTTGCCAGAAGGGGTTCGCGCGCTCCTacaagctgcagcagcataTGCGCATCCACAATGGTGAACGGCCCTACAAGTGCACCTATTGCGACAAGAGCTTCACTCAGTCAAATGACCTGACCCTCCACATTCGCCGGCACACGGGGGAGCGACCCTATCAATGCAACACCTGCGGTGAGCGTTTCATTCAGGGCACAGCACTCAAAAACCATCGCCTGCAGAACTGTCACTTCGAGACGGAGGAAGGCCAAGCTTAA
Protein Sequence
MLPTDLCRTCAQQDDNMLALSTRSEIYANKSFCDILHELTRIDSLLEPPDDKLPQYLCGDCLGKLEDAYVFVLQARQVQEQLCRLSKGLQCLDETPIDIKTETDIVLDADPNGTSQNAAPLDDDGTEVTTVYAAALKWQPASGSESGQVDDDDDDVDFKPTQLRRSARQAKLASDSEDEATSGKVKPVPVKRRRGRPARLAKKASINEDGRHACEVCGKTFSWYRDMQRHARIHFEQAAYVCDSCGKGFLRKDKYMFHLRTHEKRDAKSQALQMSNEWRFAERLYSSGRLKRLECKLCGLKCPRIQELREHVASHVTIESLSTLRMDSDVISEQFGSRQVQLDLAQIKQQVCVEIAKGREYLDKYCAVVNANGYELCLSDSDEDLAGLTPPYQCLPCNTFFTRKHRLMRHTLEEHTQTAKETPWQRCNVCQIGFLNVKLLEQHQRTQCHSQLKRYSCTKCPGKFIWLQNLKQHACSQSTMKQEDEEQQQVNESRQFQCCLCDAQLQSMTTLRDHLLIHRDGRSGIDPDHRAAFFRCHYPDGLDCSLTELGTRIACDFVAQDYGRYFNACKSNGQELDFFDSDTDLSDVEQSASSALYTCDLCGEIIMRLTNLLQHQQSQHNELDDTLPHLCNDCGLGFVAEPLLRQHRRRVCAKQHAKYHCQRCKLPFIWQSNYERHMQQEHEVEPEDDHDQVSSINLRSKRQPTSVKLQCDECEKVFIWTKDLTRHKRIHQPQTSAQYECCHCERKFHRKDGLKSHMRVHGEQQLDELAAAAISDQPATVLQRTPLVLTQLCRPNGCKQIQCMICLSQHTKISDLRTHLLTHQFVVRFAEERAKPESIASISRALYPELGTPLNKQPLIERIQSDVAKGVELERFISITNEAGIELSLDSSETDTDSDSADTERSSNGRLYGCVLCQLKVSRKHQLYAHQLEQHAWQRATWVCSHCQATFVNEQLLEHHYRTLCRNGQKRFLCRKCPLRFRWRDNLKLHTGVAHQEATVEQTNAGIPMNGARLLPVVSYDCTECNRSFKMQKDLTRHTLMHSQEANIYRCRWCARRFYRQANLLQHIERHGISAAQLPYAEALLNASRHPHGQKCIQCKVCDVRYPTIAALRSHLLSTSAGTHHDIGSMLNYSITNQLGYELHLDDSETDEEIKPPGIPPHYTCSMCQLRCVRKYELHQHQQAMHRLERIGEGCDQCIFKSVSSDLIAYHQRVLCGNTEKQFKCVKCGYMFMWESNLLLHMQLQHPSNDGQDEPASMPNVPSVDCQIFQCGQCPRKYNRKDRLTAHVKKCHTPGATGSTVTPTKTTTSSAAKQQKSFLCAFCGKAVSSSSNLIIHIRRHTGEKPFKCDYCDMAFPRSSDLQCHRRTHTGERPHICTVCQKGFARSYKLQQHMRIHNGERPYKCTYCDKSFTQSNDLTLHIRRHTGERPYQCNTCGERFIQGTALKNHRLQNCHFETEEGQA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00802986;
90% Identity
-
80% Identity
-