Halb009459.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Hirtodrosophila alboralis
Gene Symbol
-
Assembly
GCA_035043045.1
Location
JAWNNH010000375.1:83988-88651[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 26 0.0011 0.079 13.6 0.8 1 23 215 237 215 237 0.96
2 26 0.00099 0.068 13.8 1.0 1 23 243 265 243 265 0.98
3 26 0.11 7.9 7.3 0.7 2 23 297 318 296 318 0.96
4 26 0.064 4.4 8.1 2.4 1 23 395 418 395 418 0.93
5 26 8.6 5.9e+02 1.4 3.8 2 23 429 452 428 452 0.92
6 26 0.42 29 5.5 1.7 1 23 458 480 458 480 0.97
7 26 0.67 46 4.9 3.0 1 23 500 522 500 522 0.98
8 26 0.016 1.1 10.0 0.1 1 23 602 625 602 625 0.97
9 26 0.013 0.93 10.2 0.2 1 21 634 654 634 655 0.95
10 26 0.033 2.3 9.0 6.7 1 23 664 687 664 687 0.96
11 26 0.00031 0.021 15.4 0.2 2 23 715 736 714 736 0.97
12 26 1.3e-05 0.00092 19.7 3.4 1 23 744 766 744 766 0.99
13 26 0.014 0.93 10.2 0.6 1 23 917 940 917 940 0.95
14 26 0.0087 0.6 10.8 2.8 2 22 948 968 947 968 0.95
15 26 0.094 6.5 7.5 0.2 1 22 977 998 977 1000 0.87
16 26 1.3e-05 0.00088 19.7 1.8 1 23 1025 1047 1025 1047 0.97
17 26 0.00015 0.01 16.3 0.9 1 23 1054 1076 1054 1076 0.98
18 26 0.23 16 6.3 0.0 3 21 1104 1122 1103 1123 0.94
19 26 0.012 0.83 10.4 4.7 1 23 1168 1191 1168 1191 0.96
20 26 0.026 1.8 9.3 0.2 1 23 1228 1251 1228 1251 0.94
21 26 0.00029 0.02 15.4 1.8 1 23 1276 1299 1276 1299 0.97
22 26 1.5e-05 0.001 19.5 0.1 2 23 1327 1348 1326 1348 0.95
23 26 0.0001 0.0071 16.9 3.4 1 23 1354 1376 1354 1376 0.99
24 26 3.1e-06 0.00021 21.7 2.8 1 23 1382 1404 1382 1404 0.98
25 26 1.8e-07 1.3e-05 25.5 1.7 1 23 1410 1432 1410 1432 0.99
26 26 0.00026 0.018 15.6 0.4 1 23 1438 1460 1438 1460 0.97

Sequence Information

Coding Sequence
ATGTTGCCTGCAGATATTTGTCGCACGTGTGGTCAGCAGGATGACAACTTGCGGGCGCTTTCGACGAGCTCCGAAATGTACGCAAACAAAAGTTTCTGTGACATGTTGCACGAATTAACGCAAATCGatTCCTTGTTAGAACCGGTTGATGATAATCTACCGCAGTGTTTGTGCGGCGACTGCCTGCGCAAACTGGAAGATGCCTACGTTTTTGTGCTGCGGGTGCGACAAGTGCAAGATCAACTGTTTTTCAAGCTGCGCAAAGGATTGCATATACAGTGCCTTGATGAAACGCCCATAGACATAAAGACAGAGACAGACATTGCCTTGGATCCCGATCCAAATTGGGAAATCATAAATGCAGCTGCATTGAATGACGACGATCACGATATTGCAATTGTATATACTCCTGCCCTAAAATGGCATACAGACAGTGACAGCGACAGTGGCCGGGCGGACATCGATGAACATGATGTGGAGTTCAAGCCGGCGCAGCTGCGGCGCAGTGCACGAAAGGCCAAACTTGCCTCAGACAGCGAAAATGAAGCAACATCTGCCGAAGTAAAACCAGTGCCGACCAAACGTCGTCGTGGTCGTCCAGCGCGTGAGACCAAAAATGCATCCATTAACAACAAAGGTCGTCATGCATGCGAAGTGTGCGGCAAAACATTCTCATGGTATCGCGACATGCAACGCCACGCCCGCATACACTTTGAAGAAGCTGCCTATGTGTGTGATAGCTGCGGCAAGGGTTTCCTTCGCAAGGATAAATACATGTCTCATTTGCGATCGCATGAAAAGCGCGACGCCAAATACCAGGCACTGCAGATGAGCAATGAATGGCGCTTTGCAGGGCGCCTCTATAGCTCGGGTCGCATTAAGCGGATCGAGTGCAAATTGTGCGGCGTAAAGTGTCAACGCATACAGCAGTTGCGTGAGCATGTAGCAAGCCACATCACCTGTGAGACCTTATCCACCCTAAGCATTGATAGCGAAATTATAAAGGAGGAATTTGCAAGTCGGCAGCCGCAGTTAGACTTGGCAGAAATTAAGCAACAGGTGTGCGAAGACATTGCAAAAGGAGGTGAGCATCTAAACAAATACTGTGCTGTGGTTAATGCGAATGGCTATGAGCTATGTCTCAGCGATTCGGACGAGGAGCAAGTCGGCATGACGCCTCCATATCAATGCCTGccttgcaatatattttttacgcGCAAACATCGACTGATGCGTCACACGCTTGAGGAGCATACACAAACAGCAACTGCGACGCCTTTACAACGATGTGATGTTTGTCAAATTGGCTTTGTATGCGAAAAGTTTTTGGAGCAACATCAGCGCACGCAATGTCACAGCCAATTGAAGCGCTATAGCTGCACCAAATGTCCGGGAAAGTTTATTTGGTTACAGAATCTCAAGCAGCATGCTTGCTCCCATCGTATATTGCTACAGGAAGAgaaacagaagcagcagctaGACAATCAAAGTCGCCAGTTCCAGTGCTGCCTATGCGATGCCCAATTGCATAGCATGACAACATTACGGGCCCATTTACTAACTCATCGCGATGGACGAAGCGGCATCGATCCTGATCAGCAGGCTGCTTTCTTTCGTATCTATTATCCAGATGGTCTTGCTTGCAGCATAACGGAGCTGAGCACTCGCATTGCCTGCGACTTTGAGGCTCAGGATTATGGACGCTACTTTAATGCCTATAATACCTACACAGGCCAGGAGATGGACTTCTTTGACTCGGACACCGACTGCAGCGATGCAGAACAGCCGGCGACCTCAGCTTTGTATACGTGTGCTTTGTGCGGTGAGGTTATATTTAAGCTTGCCAATCTTCTTCAACATCAACAAAGTCAACACAATGATGTGGAGATCACACTGCCTCATGTCTGCCTCGATTGTGGCTTGGGTTTTGTAGCTGAATCGCTGCTCCAACAGCATCGCCGACATGTGTGTGCCAAGCAACATGTTAAATACCACTGCAAGCATTGCAATCTTCACTTTATCTGGCAGTCCAACTACGAACGGCATATGCAGCAAGAGCATGAGACGGAGACATTAGATGCCAATGATCAGATGCCCAGTATTTCGCTAAGAAGCAAACGCCAAGTAACATCCGTCAAACTGCAGTGCGACGAGTGCGAAAAGgTCTTCATCTGGCCAAAGGATTTGACGCGCCACAAGCGCATTCATCAGCCTCAGACATCTGCACAGTACGAGTGCACCCAATGCGAACGCAAGTTCCATCGCAAGGATGGTCTCAAATCACATATGCGGGTGCACGGCGAACAGCAAAAAGACGAGGCAACGGCCTTAGCCATCAGTGATCCACAAGCGGTGGTGCTGCAACGCATGCCAATGGTGTTGACGCAATTGTGCAGGCCCAATGGCTGCAAGCAGATCCAGTGCATGATTTGCCTCTCTCAGCATACAAAGATCTCTGATTTGCGAACTCATTTGCTGACGCATCAATTTGTGGTTAAGTTTGAAGAGGAGCGTGCCACGTCTGAGAGCATTGCCAGCATTAGTCGTGCACTATACCCGGAGCTAGGACCACCACTGGAGAAACAAGAATTGATCGAGCGTATTCAGAGCGATGTGGCCAAAGGTATTGAACTGGAACGATTCATTTCAATAACCAATGAGGCAGGCATTGAGCTAAGTCTGGACAGCAGCGAAACTGAAACAGATTCGGACTCAACAGATACAGAAAGAAGCAACATAAGACGACTGTATAGCTGTCAGCTATGTAAGGTGAAGGTGCCGCGCAAGTATCAACTTTATGCCCATCAGCTGGAGCAGCACGCCTGTCAAAAGGCCACATGTGTGTGTTCCCACTGCCAGGCTACATTTGTCAATGAGCAACTGCTGGAGCATCATTATCGCACACTTTGCCGCAATACACAGAAGCGTTTTCTCTGTCGCAAATGTCCATTGCGTTTTCGCTGGCGTGATAATTTGAAGATGCACATAGGCGCTGCACATCAAGAAGCAACTGGAGATCAGTCGCACTTGGGCATTCAATTCAATGGGACACGTTTGTTGCCCGTTGTCAGTTATGATTGCAGCGAATGCAATCGTagctttaaaatgcaaaaggaTCTAACACGCCATACGCTGATGCATGCCCAGGAGTCGAGCATTTATCGGTGTCGCTGGTGTGCGCGTCGCTTCTATCGTCAGGCCAATCTGCTGCAGCATATTGAGCGTCATGGCATTAGCGCCGATCAGCTGCCTTATGCCGAGGCGCTGCTCAATGCAAGTCGGCATCCGCATGGCCAGAAGAGCATCCTATGCAAGGTGTGTGATGTCCGTTATCCCACCATAGCCGCATTACGCTCCCATTTGCTGTCCACGCCGGAGGGCTCGCATCATGACATAGACTCAATGCTCAATTACTCGATTACCAATCAGCTAGGCTACGAGCTGCACCTGGATGACTCTGAAACAGATGAGGAAACTAAGCCTCCGGGCATGGCCACGCACTACACATGCAGCATGTGTCAACTACGTTGTGTGCGTAAATATGAACtccatcagcatcagcaggcCATGCATCGGCTGGAACGCATTAGTGAAGGTTGTACTCAGTGCATCTATAAGAGTGTCTCACCGGATCTCATTGCCTATCATCGGCGCGTGTTGTGTGACAACACAGAAAAGCAGTTTAAGTGCGTCAAGTGTGGTTACATGTTCATGTGGGAATCAAATCTTTTGCTGCACATAGAGCTGCAGCATCCAAGCAACGAGGGACAAAAAGAAATGGCCTCTATGCCAGCACTAGATATGCCCAGTGTTGAATGCCAGATCTTCCAGTGTGGCCAGTGTCCCCGTAAATATAATCGGAAGGATCGATTGACTGCGCATGTAAAGAAATTTCATACACCAGGCGCAACTGGCTCGGCTGGGTCTccaacaaaagcagcaaagaCATCCGCCGCTGCCAAGCAACAGAAAAGTTTTCTCTGCGCCTTTTGTGGAAAGGCGGTGAGCTCCTCCTCGAAtctaattatacatatacgaCGCCATACAGGCGAGAAGCCATTCAAGTGCGATTATTGCAACATGGCTTTTCCGCGCTCCTCCGATCTGCAATGCCATCGTCGCACCCATACAGGCGAGCGGCCACATACCTGCACCGTTTGCCAGAAGGGATTCGCCCGTTCCTATAAGTTGCAACAGCATATGCGCATCCACAATGGCGAACGTCCCTATAAGTGTACATATTGTGATAAGGGCTTCACCCAATCAAATGATCTGACGCTCCACATACGTCGACATACGGGCGAGCGTCCCTATCAATGCGATACCTGCGGTGAGCGCTTTATTCAGGGCACAGCACTCAAGAATCATCGTCTACAGCATGGCCACTACGAGACGGAGCAGGGCCAAGAAGGTAAACTTAActaa
Protein Sequence
MLPADICRTCGQQDDNLRALSTSSEMYANKSFCDMLHELTQIDSLLEPVDDNLPQCLCGDCLRKLEDAYVFVLRVRQVQDQLFFKLRKGLHIQCLDETPIDIKTETDIALDPDPNWEIINAAALNDDDHDIAIVYTPALKWHTDSDSDSGRADIDEHDVEFKPAQLRRSARKAKLASDSENEATSAEVKPVPTKRRRGRPARETKNASINNKGRHACEVCGKTFSWYRDMQRHARIHFEEAAYVCDSCGKGFLRKDKYMSHLRSHEKRDAKYQALQMSNEWRFAGRLYSSGRIKRIECKLCGVKCQRIQQLREHVASHITCETLSTLSIDSEIIKEEFASRQPQLDLAEIKQQVCEDIAKGGEHLNKYCAVVNANGYELCLSDSDEEQVGMTPPYQCLPCNIFFTRKHRLMRHTLEEHTQTATATPLQRCDVCQIGFVCEKFLEQHQRTQCHSQLKRYSCTKCPGKFIWLQNLKQHACSHRILLQEEKQKQQLDNQSRQFQCCLCDAQLHSMTTLRAHLLTHRDGRSGIDPDQQAAFFRIYYPDGLACSITELSTRIACDFEAQDYGRYFNAYNTYTGQEMDFFDSDTDCSDAEQPATSALYTCALCGEVIFKLANLLQHQQSQHNDVEITLPHVCLDCGLGFVAESLLQQHRRHVCAKQHVKYHCKHCNLHFIWQSNYERHMQQEHETETLDANDQMPSISLRSKRQVTSVKLQCDECEKVFIWPKDLTRHKRIHQPQTSAQYECTQCERKFHRKDGLKSHMRVHGEQQKDEATALAISDPQAVVLQRMPMVLTQLCRPNGCKQIQCMICLSQHTKISDLRTHLLTHQFVVKFEEERATSESIASISRALYPELGPPLEKQELIERIQSDVAKGIELERFISITNEAGIELSLDSSETETDSDSTDTERSNIRRLYSCQLCKVKVPRKYQLYAHQLEQHACQKATCVCSHCQATFVNEQLLEHHYRTLCRNTQKRFLCRKCPLRFRWRDNLKMHIGAAHQEATGDQSHLGIQFNGTRLLPVVSYDCSECNRSFKMQKDLTRHTLMHAQESSIYRCRWCARRFYRQANLLQHIERHGISADQLPYAEALLNASRHPHGQKSILCKVCDVRYPTIAALRSHLLSTPEGSHHDIDSMLNYSITNQLGYELHLDDSETDEETKPPGMATHYTCSMCQLRCVRKYELHQHQQAMHRLERISEGCTQCIYKSVSPDLIAYHRRVLCDNTEKQFKCVKCGYMFMWESNLLLHIELQHPSNEGQKEMASMPALDMPSVECQIFQCGQCPRKYNRKDRLTAHVKKFHTPGATGSAGSPTKAAKTSAAAKQQKSFLCAFCGKAVSSSSNLIIHIRRHTGEKPFKCDYCNMAFPRSSDLQCHRRTHTGERPHTCTVCQKGFARSYKLQQHMRIHNGERPYKCTYCDKGFTQSNDLTLHIRRHTGERPYQCDTCGERFIQGTALKNHRLQHGHYETEQGQEGKLN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00803744;
90% Identity
-
80% Identity
-