Basic Information

Insect: Hirtodrosophila confusa
Gene Symbol: Hr39
Assembly: GCA_035043065.1
Location: JAWNNI010000148.1:6187367-6190695[-]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 0.075 9.4e+02 -0.6 5.0 52 207 54 213 26 218 0.51

2 3 1.3 1.7e+04 -4.7 12.4 40 155 196 322 188 347 0.41

3 3 6.8e-99 8.4e-95 319.0 11.8 1 408 486 874 486 874 0.84

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	0.075	9.4e+02	-0.6	5.0	52	207	54	213	26	218	0.51
2	3	1.3	1.7e+04	-4.7	12.4	40	155	196	322	188	347	0.41
3	3	6.8e-99	8.4e-95	319.0	11.8	1	408	486	874	486	874	0.84

Sequence Information

Coding Sequence: ATGCCGAACATGTCCAGCATTAAGACGGAGCAGAGTGTCTCCCCGGGCGTCAGTGGGAGCTACCAGCTGCCGGTGAACATGTCCACAACGACGGTAGGGGGCGCCACAGTGCGTCACAATGTGTCCGTGACGAACATCAAATGCGAGCTGGACGAGCTGGCAACGCCGAACGGCAACCTGGTTCCGGTGATAGCCAactataataatcataatcataatcacaATCAGAATCACAGCAGTGgaaacggcagcagcagcctgtgCATACCGCTGAGCGGCAAGCTGCACAATGAGGATGACTCCGAATCGGAGGCGGAGCTGGCTAATATTGAGAATCTGAAGGTGCGACGACGCGCCGCGGACAAGAACGGGCCGCGTCCCATGTCCTGGGAGGGTGAGCTCagcgagaacgagaacgaggcGCCCGATGAGGAGCTGATGGAAACGGAGACGGTCATCAAGAGCGaggcaagcagcagcagcagcagcgtgggCGGAGgcacaacagccacaacaatgGCCAGCAGCCAGGTGGCAGCCATGCTGCAGCCCATCAAGCGGGAGCTGGAGCACATAGCCGGCGAATTGCAGCTGcaaaatcaacagcaacagttgcaacagcagcagcagcagcacttgcaacagcaacagttgcaactgCAGCCAGTCAAGCAAAACTTTGCGCCCAACAACAAGCTGAAGCTGGCGCCCACACAAAGCGATCCCATCAATCTGAAATATGAGCCCGCCTGCTCGGTGCTCTGCGATCGCAGCAAGTCCAACAGCGGCGGCcatttgccgctgctgcccgCCAATCCCAGTCCAGACTCTGCCATACATTCCGTCTACACGCACAGCAGCCCCTCGCAGTCGCCGCTGACGTCGCGGCATGCCCCCTACACGCCCTCGCTGAGCCGCAACAACAGCGACGCCTCGCACAGCAGctgctacagctacagctccGAGTTCAGTCCCACCCACTCGCCCATCCAGGCGCGCCATGCGCCGCCCGCCGGCTCAGCGCTGTTTACGACGGCCAATGCCAATGGCGTCGGTCCAACCGCTGCACTGCATCATCATAGCGTGCTGTATAGGCCGCTAAACGTGGATGCTGCCGCCGTGGCGGCTGGAGCGGCTGGTGGCCAGGAGGCGCAAAATCTCAGCATGGATGGCACACAGCTGGATGCCACGGCCACGCTGCCAGCCTCACCGGCGGGCATTTCTCGACAGCAGCTTATTAACTCGCCGTGTCCGATTTGTGGCGATAAGATCAGCGGCTTTCATTATGGCATCTTCTCCTGCGAATCCTGCAAGGGCTTCTTCAAGCGCACCGTGCAGAATCGCAAGAATTATGTTTGTGTGCGCGGCGGACCCTGCCAGGTGAGCATCTCCACGCGAAAGAAGTGCCCGGCCTGCCGCTTTGAGAAGTGCCTGCAGAAGGGCATGAAATTGGAGGCCATACGGGAGGATCGCACACGCGGCGGCCGCTCCACCTATCAATGCTCCTACACGCTGCCGAATTCAATGCTCAGTCCGCTGCTCAGTCCCGATCAGGCggcagccgctgcagcagctgccgccgttgtcaatcaacagcagcagcatcagcaccaacagcaacaacagcaacatcagcgcTTGCaacatcaccatcatcatcatcagcaacagcagcagcagcaacatggccCCCTCAATGGCTTTGGCGGTGGTGGCTCCAATTCCCTGCCCGCCAGTCCCAGTCTCGGCGCATCCATCAAGACGGAGCAGTTGGAGCCGCTCAATCATCACACGTCGCGCGCCTCAAGCATTCCAGCCCTGTTGCAGGAAATCATGGATGTTGAACATCTCTGGCAATATACCGACGCCGAACTGGCACGCATCAATCAACCGCTGTCCTCATTTGCAACTGGCGGCTCTGGATCGGGCACCGCGGGCGGCTCGGGGTCAGCTGGACAGCACACTGCCAATGCACAACAGATGACCAATCCACTGCTGGCCAGTGCTGGTCTATCGTCCAACGGGGAGAATGCCAATCCCGATCTGATCGCACACCTCTGCAATGTGGCCGATCATCGCCTCTACAAGATTGTCAAGTGGTGCAAGAGTTTGCCGCTCTTCAAGAACATCTCGATTGACGATCAGATCTGCCTGCTCATCAACTCGTGGTGTGAACTGTTGCTATTCTCCTGCTGTTTTCGTTCCATTGATACGCCTGGCGAGATTAAGATGTCACAGGGCAGAAAGATAACGCTGGCACAGGCAAAAACCAATGGCCTACAGGCCTGCATTGAACGCATGTTGAATCTGACCGATCATTTGCGGCGTTTACGCGTTGATCGCTATGAATATGTTGCCATGAAGGTAATCGTGCTGCTGCAGTCCGACACCACGGAGCTGCATGAGGCGGTCAAGGTGCGCGAGTGCCAGGAAAAGGCGCTGCAGGGTCTGCAGGCATACACGCTGGCCCATTATCCCGATACGCCGTCCAAATTTGGGGAGCTATTGCTGCGCATACCCGATCTGCAGCGCACGTGTCAGCTGGGCAAGGAAATGCTGACGATCAAGACACGCGATGGTGCCGATTTCAATTTGCTAATGGAACTGCTACGCGGAGAGCATTGA
Protein Sequence: MPNMSSIKTEQSVSPGVSGSYQLPVNMSTTTVGGATVRHNVSVTNIKCELDELATPNGNLVPVIANYNNHNHNHNQNHSSGNGSSSLCIPLSGKLHNEDDSESEAELANIENLKVRRRAADKNGPRPMSWEGELSENENEAPDEELMETETVIKSEASSSSSSVGGGTTATTMASSQVAAMLQPIKRELEHIAGELQLQNQQQQLQQQQQQHLQQQQLQLQPVKQNFAPNNKLKLAPTQSDPINLKYEPACSVLCDRSKSNSGGHLPLLPANPSPDSAIHSVYTHSSPSQSPLTSRHAPYTPSLSRNNSDASHSSCYSYSSEFSPTHSPIQARHAPPAGSALFTTANANGVGPTAALHHHSVLYRPLNVDAAAVAAGAAGGQEAQNLSMDGTQLDATATLPASPAGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCVRGGPCQVSISTRKKCPACRFEKCLQKGMKLEAIREDRTRGGRSTYQCSYTLPNSMLSPLLSPDQAAAAAAAAAVVNQQQQHQHQQQQQQHQRLQHHHHHHQQQQQQQHGPLNGFGGGGSNSLPASPSLGASIKTEQLEPLNHHTSRASSIPALLQEIMDVEHLWQYTDAELARINQPLSSFATGGSGSGTAGGSGSAGQHTANAQQMTNPLLASAGLSSNGENANPDLIAHLCNVADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSIDTPGEIKMSQGRKITLAQAKTNGLQACIERMLNLTDHLRRLRVDRYEYVAMKVIVLLQSDTTELHEAVKVRECQEKALQGLQAYTLAHYPDTPSKFGELLLRIPDLQRTCQLGKEMLTIKTRDGADFNLLMELLRGEH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00575636;
90% Identity: iTF_00805215;
80% Identity: iTF_00803649;