Basic Information

Insect: Himalopsyche kuldschensis
Gene Symbol: Hr39
Assembly: GCA_028554975.1
Location: JAHFWI010000022.1:3356517-3368397[-]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 3 2.8e+04 -10.2 12.5 19 84 207 279 58 315 0.67

2 5 3 2.8e+04 -11.0 15.0 20 98 208 336 204 449 0.52

3 5 1 9.7e+03 -3.8 4.9 54 113 379 436 332 495 0.52

4 5 6.7e-12 6.3e-08 33.1 0.3 1 146 589 728 589 742 0.69

5 5 6.3e-69 5.9e-65 220.9 0.0 204 408 741 943 732 943 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	3	2.8e+04	-10.2	12.5	19	84	207	279	58	315	0.67
2	5	3	2.8e+04	-11.0	15.0	20	98	208	336	204	449	0.52
3	5	1	9.7e+03	-3.8	4.9	54	113	379	436	332	495	0.52
4	5	6.7e-12	6.3e-08	33.1	0.3	1	146	589	728	589	742	0.69
5	5	6.3e-69	5.9e-65	220.9	0.0	204	408	741	943	732	943	0.95

Sequence Information

Coding Sequence: ATGGCCAGTACCGCAGCGGGAAATTCGCTGCCTGAAGTTGGTGCCAAGATCGAAGGCGGGAGAAATGTTTCTGTTACTCCAATCAATATGTCAGATTCCCAAATGACGAATGGACAATTCTCATACAGCTCTAATGGCGTGCGCATCAATGTGCCGTCAGAAGAGCAGCGGAGGCCTCTCATCGCCATGGACGATGAGGATTCCAATGATGCTGAAGTCTCCAAGATCGACTTCATGCAGCATCAATATCAGGTCAATATGCGGACAAAGAAAAAGCGCCCGTCTTCCAGCTCGCATGCATCTGCCCCGAGTGAGATAAGCATTCATTCCGACCAGATGCCTGAAGCACTATCCCTCGAACGCGAACGTCCCATGTCATGGGAAGGTGAACTCTCCGACTCGGAAATGCCCGTGGAACCGATACAACAAAGCCAAGTGTCAAACCAACAGCAATTGCAACAGCTACATCTGCAGCAGATGTGCAATGAACAGATACACGGTATCCCCAGGGCGTCTGAAGACTTTCGGTTGAAAGAAGAATTTAGACCAAAGGAAGAGCCTTTGGATGTCACACACAACTTTTTGAATCATCATCATCATAATCAGTTGACGATAGGGAGACAGGACAATGCGATGCGACATCATCATCTACAGCATCATCAGAGGAGTCATAGTATGAATCGGGTATCTGTTTTATCAGGAGACATCCCTGACATCCGCTGCCCTTCTTCCCCTCAATCGCTACACAAACTTTCATCAGTCTGCCCGCCGTCTCTGCCCTCCGAACAACCGCCGCAATCCACACAACCGCTATCAACAGTCTCACCCGCTTCCACGTTAGAACAGACAATCAAGAATATCCCCGTCAACATCATTCCCACATCGCTTAGCAATAAGATGGCATCAGAGGCACACGCGTATGCTTGCAAAAGAGAACAGATAAACAACCTGCAGCAAGTGCCAAATCAACTGGGACAAACTATCTTGCCAGACATCAAACCTGAAGTTCCTCTTCTTGTAGACAAACTGTTGGGCGGTTACTCTATTCACAGCACTCCGAGCAACTCGCCTCTCCTCAACAGGCATCATAAAATCATGTCGAACCCGAGTACCGACTCAGCCATACATTCCGTTTACACACACAGCGTGTATAGTAGTCCATCAGCAAGCCCCGGAGCCACCCGCCATGCACCCTACACTCCATCTCTCTCTCGAAACAACAGCGATGCATCTCATTCTTCATGTTACTCCTACAGTTCAGAATTCAGCCCCACTCATTCCCCCGTTCAGGGTCGGCATCCGATCCCCGCGCATGCAGCTGCACTATTCCGTACAGAGCATGGTGCATTTCCCACATCTCGGCCTCATCATTTATCATCCGTATCATCAGTGTGTATGCAAGAAGGGGGGATCACATCTGGTAGTAGTTGTGCTGGTCTCGGTGCGATGGATTCTGGCGGGGGTGGAACAGAAGCCGGAAGTCCAGATCCCGAAGGCCCAGAAGACAGAGTGCATCACCATCAAGGAGTCAGCAGGCAACAACTAATCAACAGCCCATGTCCGATATGTGGAGACAAAATATCTGGCTTTCATTATGGAATATTCTCCTGTGAATCCTGTAAAGGATTCTTTAAAAGAACAGTGCAGAACCGAAAGAATTACGTGTGCTTAAGAGGTGCCAACTGTCTCGTCACTGTTGCTACCAGAAAAAAATGCCCTGCGTGCCGATTCGACAAATGTTTACATTGTGGAATGAAGTTGGAAGCAATAAGAGAAGACAGAACACGTGGCGGTCGATCTACATATCAGTGTTCATACAGCCTGAGTGGAGCAGCTTCCACCAGTTCACTTCTTGGTGCAGGATTAAGTTCTGGTCCCCTCAGACATGCCTCCAGCCTCACATCTGTGAACGGACCTTCATCACATCACTCATATCATTCACAACATGATCTTCATACGTCGTCTCTGGGAGGCAGCTCCCATGGTATGTCAATGGGAGTGAAAAGTGAACCTGGACATCATAGTGTGCATTCCAATAACATGGCTGTACCTCCACTGCTGCAGGAAATAATGGACGTAGAACACCTCTGGCAGTACAACGAATCGGAACTGAACAAATTAAATAAGGGTCAAGCATTGGGCAGCGGAAGTCAAAGCTCATCATCATCAGCCGCATCTATGATGAACAATCCTCTTTTGAAAGCTGCAGGTGTTTCGGCTGATTCCAGTCCTGACTTCCTCGCCAACCTGTGCAATATCGCTGATCATCGATTATATAAGATTGTCAAATGGTGCAAGAGCTTACCTCTCTTTAAAAACATATCTATTGATGATCAAATTTGTCTGCTTATAAACAGTTGGTGTGAACTTTTAGTGCTATCGTGTTGCTATCGAGGAGTTGGCACTCCTGGAGAAGTGAGAGTGGGAGGGGGCAGCCGGGGTATTACATTAGAACAGAGTAGCAAGATGGGCTTGACACCTTGCATAGAGAGAATGCTTCATTTCACCGATCATTTGAGAAGATTGCGGGTGGATCGATACGAGTATGTCGCTATGAAAGTCATCGTTCTTCTCACTTCAGATATATCTGAGTTGAAACAGCCTGAAAAGGTGCGAGAGTCTCAAGAGAAAGCACTTCAAGCTCTGCAAGCGTACACGCTGGCACATTATCCAGAAACACCCGCCAAGTTCGGAGAGCTTCTACTCAGGTTACCTGAATTGCAGCGTACTTGCCAGGTTGGCAAGGAGCTGTTAAATCCAACAAACAAATCTAAAGATGGTGAGACTCCGAGCTTCAATCTGCTCATGGAGCTACTCCGGGGAGATCACTGA
Protein Sequence: MASTAAGNSLPEVGAKIEGGRNVSVTPINMSDSQMTNGQFSYSSNGVRINVPSEEQRRPLIAMDDEDSNDAEVSKIDFMQHQYQVNMRTKKKRPSSSSHASAPSEISIHSDQMPEALSLERERPMSWEGELSDSEMPVEPIQQSQVSNQQQLQQLHLQQMCNEQIHGIPRASEDFRLKEEFRPKEEPLDVTHNFLNHHHHNQLTIGRQDNAMRHHHLQHHQRSHSMNRVSVLSGDIPDIRCPSSPQSLHKLSSVCPPSLPSEQPPQSTQPLSTVSPASTLEQTIKNIPVNIIPTSLSNKMASEAHAYACKREQINNLQQVPNQLGQTILPDIKPEVPLLVDKLLGGYSIHSTPSNSPLLNRHHKIMSNPSTDSAIHSVYTHSVYSSPSASPGATRHAPYTPSLSRNNSDASHSSCYSYSSEFSPTHSPVQGRHPIPAHAAALFRTEHGAFPTSRPHHLSSVSSVCMQEGGITSGSSCAGLGAMDSGGGGTEAGSPDPEGPEDRVHHHQGVSRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCLRGANCLVTVATRKKCPACRFDKCLHCGMKLEAIREDRTRGGRSTYQCSYSLSGAASTSSLLGAGLSSGPLRHASSLTSVNGPSSHHSYHSQHDLHTSSLGGSSHGMSMGVKSEPGHHSVHSNNMAVPPLLQEIMDVEHLWQYNESELNKLNKGQALGSGSQSSSSSAASMMNNPLLKAAGVSADSSPDFLANLCNIADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLVLSCCYRGVGTPGEVRVGGGSRGITLEQSSKMGLTPCIERMLHFTDHLRRLRVDRYEYVAMKVIVLLTSDISELKQPEKVRESQEKALQALQAYTLAHYPETPAKFGELLLRLPELQRTCQVGKELLNPTNKSKDGETPSFNLLMELLRGDH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00800257;
90% Identity: iTF_00800257;
80% Identity: iTF_00801043;