Hkul023876.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Himalopsyche kuldschensis
Gene Symbol
egg
Assembly
GCA_028554975.1
Location
JAHFWI010000092.1:1953632-1975619[+]

Transcription Factor Domain

TF Family
MBD
Domain
MBD domain
PFAM
PF01429
TF Group
Unclassified Structure
Description
The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 2 1.1 6.1e+03 -2.5 0.0 29 38 1563 1572 1545 1574 0.78
2 2 9.4e-13 5.3e-09 36.2 0.0 3 71 1603 1664 1601 1669 0.87

Sequence Information

Coding Sequence
ATGGCTGACGCTCCTGCTGAAATTAGCAAAAAAGAAGATGAGCTTGATTCACCAAGCGAAAATACAATAGCAGACAAGGATTCTGATCCTCCGGAAAAACCTACAAGTTCGGTTGACCCGGTCCCAATGGAAACAGACTCTACAACAGACCCAGATGTCGCTAAAACAACAGGCGATGTAAATACTGTAAAACCAGAAGTCGGCCGGGATGTTGAAAGTATTGAATCAATTATGCAATTTTTGATGAATTCTGATGATGCGGCAGCTGGTGATCCCCAAGAACCGTGCATCCCAAAAGAAAAAGAAATTGATACCGTTGCTCTAAATATTCCTGTCTCCGAAGTACCGGATATCTTCCCCGAAGAAACAATGGATACTGATGTAACTAGTCCCACTGGAACTAGTCCCACTGCAATTAGTCCCACTAAACCAAGTCCCACTGAAACAATTCCCACTGACGCAAGTCGCGCTGCGACAGCTAGTGAAGAAAATGTTGTGGAGAAGATTGTAAATGCTGAAAGTACTGCCAGCGTGATTGCAGATAGTACTGAAAAAAATACGTCATCCATCAATGATGCCACTGTGGAAAAAGAAACAATATCTGATTCAAAAAAGGAAAAAAACAATGAAAGTGAGAGTGGTTTTGGTGATGCATCCAACAGTACAAACACCGTTGATCCGGTCACTCGAGAATCTCAAAACGCCACTGAAGCAGATGATGCGTCAATGGATGGCATTCATGATTCGGAATTGGATGGCCTTTTGGTGGAGGGCAATGCCCGCTACAGGGGAGACAGTGATCAATATGATGACGAGGATATCTCCGATGATCATTCTGCTGAAGGCGTTGAAGGATTGGGCTACAGAGGGGGTCTaggtgatgattctaaccaaggatacggtgatcgtacctctgacatagacgatgaagattttgttcctacacaagatgaagacgaagatgacgatgatgacggcgacgatgatgaagacgaagatgatttaggaaacagtcgacgccgtTATAATAAAAAAATAGTAAGGCGGCCATCTTACCAAGGCCAGAGGCCACCCCCTGTAAAAACTGATGAAGATTTTGCTGATGATGAAAATGATGATGGCATTTCCAATCAATCCGTTGACAATGCGACTGATTCTTTTGGAAATGTCCAATTGCAGGTAGAGTCTGCAGTCTTCGACACCGATGAATCCATCGGAGGCGTGAGATCACCAACTGTTGAAAACAATGAATCTTCAATCGCAATGGAGGACGTTTTGATGGACGTGGATTCGGATAGCCGTCAAAACGGTGAATGTTCATTAGACATTCAAATTGTTTCCGTAGATGGAAATATCGGAATTATGATTGATAAAACCATTCAAGAAAATGACCCACCTGTTGAACCATGCGTGGAAACTGCTGAAGCGTTAAATTCAAGTGTAAATTTAGATTGTGAGCAATCTGAATCTCTAACCTCTACGGAGGTTGTGACCTTGCAAACACCTGTTGTTGAAGCCATTGTAGATATCAAAGAGAGTCAATTGACAACGAAACTTGATGAAGGTATGGAAAAGTTTAGTAAAAATTCAGTAGTCAATGTTCATATGTCAGCTGAAGACACTTTACTTGAAGAGAAAGCTTCAAATGAAAATGCAGAGTTGCTGCTAAAATCTCCAGATGTTACTTTAACCGGCCCTCAAACTATGGATGCACATGTTCCAATGAACCATGAAAAAACCGCAGAGGACTCCAATGCTACCCTAGAAGAATTGAATATTAACAGTTCCGTTAAAGAAACAGTTGAAATAGTCATTGAGGCCGCAATACCTGAAAATGTTGATGCATCGATACCTGTGGAAATCCACAAGCCACAAGATGAAACAATGGAAGTAGAACAGGAAAAGATATCTGAATCCATGGAAGTCGATTCTGGAGATAAAGAAGTTCAAGACTCCAAAAGTCAAGCATCACCTTCGAAAATTATTTCTGAAATTAATAGAGCAGCAAAGGCATTTGAGGATTGCATTATTTCATCTAAAACGTCTACTTTAGCCACTGTTGATGTTCAGAAACATGAAGACATGGAAACTGTTGCAGAAAATGAAGCACTTGATAAAAATATTGAAAAAGCTCCCGCAGATGAAATTCCAAAGGATCTACCTTTGAAAAGTAAAATAGAAGACAAGAAAGATACTGTACTAGCAAAAACCAGCAGATTGAGCATAGCTAATGAAGCAACCAAGGTCACTGAAGATATTGTCTGCCTGGAAGAGACTTCTTCTGATTCAGACGCCGGTACGAAAGCGAAGGAACTTGAGAAAAAAATAATTAAAACTGAAGCAGATACGAAACCAGAGCTGATATCGGAAGAATCAATAGCCAAGCCACTCACTACAGCAAAATCCACACCTGCTGTCGTGAAACCTGCAGCAGGTATCGCAGTCCCGAAGACCCCAGCAACTACCGTGTCTCCTACTAAAGTGACGGAGATATTCTCATTGGATTCGGACGACGACGACGTCATTCCGGAAGTCAAGAAGCCTGAAAAAAAATCTCATCCGAGGTCTACGCCGGTCGCAAAGAAGCTCACAGCCCCGAGAAGGTCTTCTTCCAAGAAACAATCCTCCGGAAAGTCCACAACTAAAGAAGGAGACAAGAGTGTTTCAGGTGACAGTGCAGACAAATTACTGGTAGAACTTTGCGCGAATCCTCGGTGTCAGTCAGGTCCTAAAGGAAGTATCAAGCTGGAGGAGAGTCCTTCCGTCGCCCTCTCTCTCCATAGAGCCACCCAAAGTGGAAAACTCTGTGTCGCTTGTTTACAGGAGGCCATTGGATGTGCAGAGCGTTTGGTGTCTGGACTGCGTGCAGGCGCCAATCTGTACAAAATTATCCTGCCGCACACCGAAGACCTGGTGGAGATATCCTCGTCAGATTCAGAAACCACAGAAGACCAACCTAAGTTCCTAAAGCAAGCCGCAAAGAGAAATAAGACTAAGAAGTCCCCGAAAGTGGACGGCGACAATCAGTATAGCTTAACGGACGATGAAATGTTACTCATAACTGGAAAAATTGAAAAGGCCGTGGAAGACATTTGCTCCAAATTCAATATCAACAAACACATCACCTCTTATGAAGAATCTATCAGACAAGATTTAATATTACTCGAGAAAGATGCCATGGAGTTTGAATTAGAGCTGTCCGAATTGCAGAAGAAGACCGACGGTACAAGGAATTACTTCTACGACACCTTCAAACCGCCCACCTGCGCCGTGCTGGAATTGTCAATCAATTCATTGATCGATGAACGGACTGGACAGGACTTTCATAGACAGACAATCGATCTGGCCGACGATGAATGGACTCCCGACAGGCTAGGATATAGTGCAAAGAAAAAGTTGTCGACTACTCCTGAAGTTCAGGATGTCACTGAAAGGAGGTCAACAAGGCTGCGAAAACCCGTCAATTACAATGTAGATACCGAAGAAGCCCTCCAGCAAGCGGCGTTAGTCGCAGGCCTCCGTATACCTAATGCTGCAGAGTGTGAGGCTGCTCTACCCCCTGAGGGTCCAGAAGAACGTGTGCTAGTCCCCTTAAAAGTTGGCGATGTTATGTATGCAGTTCGGCACTCCATCTTTAGTGCCTGGGTTCTGGCCACAATTATGGAAATATGGCCAAAAGGGACCATGCTATCCAATGGAACACTGGCGCTGTTCACTCTGATGACGGTGAAATTCGAAGCTGCGGCCAGGGGTGAAGGCTTTGTCATAAAGCAAGTGACCGGTCGTCAAGTGGCATGTTTGAAACCTTCTGCATTCAGATATACCATCGGTACAAGAGTGATAGCTCTCTTCAAGGATCAGACGCAACAGAAGAAAAAGGACGCTTATTATTCAGGTGTAATTGCAGAAACACCTTCGACTTCCAACATTTTCAGATATCTCGTATTCTTCGACGACGGTTACGCTCAGTATGTCAAACACACTGACGCCATAAGGGTGTGCGAGATGTCGCTCCGAGTTTATGAAGATGTCCATGCCGATTCGAGGGATTTCATCAAAAAATATCTGTCCATGTATCCCGACAGAGCCATGGTTCGAATGCAACCCGGTCAGGAAGTTAAAGTCGAATGGAGCGGAAAGTGGTGGGCATCGCGAGTGTTAGCCGTGGACAGTTCATTGGCATTGATGCGTTTTGAGGAAGGTGAAAATACAGTCGTTCGGGAAGAATGGATCTACAGAGGTAATGCGAGACTGTTGCCACTGTTCTTGGAGTTGCAAGCTGCCGATAGACGAGCGCAGGGAAGACACAGAGCTCCCGGGGCCACATCCAATACCAACAAGATGGCGAACTACCCTTACGTGGAGTATACACGCTTGGATGAAGTAACAACAATACCCCCCATGCCAGCAGATAATGTTGCACCAATTATACCTGTAGCAGTACCGGTTCCGATCTCAAGTGCGATTCCAGCATTTACTCCTCTTCCAACTGCCCCGACGCCATTGCCAGCACCACCGCCAACTTCTCAAGTGGTCCCATCTGAACCAAGAGCCGTCGCCAAGAAAAGCACAACCCACCGAAAGAAAGATTCTAAGCTGGAACATGCCGTTACCCCTGCGCTTCCTCAGCCTCAGATCCCGCGGAGAGCTACTCCGGCCGGGGCTATGGAACCTCATTCTGATCAAGTTCGCAGTAAAGTTGTGTACTACACTCCAAAAGTGAAAGTTAAACCGAAGAAACTCGCACCGCATGCATGCTCTCCCAATTGCCTCAACAAAGATGCCCTCCCTCTTAGGATTCTCAAGACTCACAATCCACTGGCCAGACCCTTGTTATCGGGATGGGAGAGACTGATAATGAAATCTCGAGCCAAGCGTACTATTATGTACAAGGCTCCTTGCGGCAGGAGGCTGAGGTCCCCCCAAGAACTTCATCTGTACTTGAGACTCACTGCCTCCGAAATGAGCGTAGATCTTTTTGACTTCGACCACTGGGTACACTGCCTGGCTGAATACGTTCTCACCAAGTGTTTTGTGACCAAACATGATATTTCTCACGGGGTTGAAGCTGTTCCGATACAGTGCGTAAACGACTGCGATCACACCTTACCTCAGTTCTGTGCGTACAGTACACGCAGGATACCAACGCAAGGTGTGGATTTGAATCTTGATCAAGAGTTTCTCTGTGGGTGCGATTGCACTGATGACTGTCAGAACAAGGAGACGTGTCAATGCTGGCAACTGACTTACGAAGGTGCTAGGGTTGTCGGATATGACCCCAACCGTGTAGGGTATCAGTACAAGAGACTTTTGGAACCTGTCCCCACTGGAATTTATGAATGCAATTCTAGGTGTAAATGCGCTATGACTTGCTTGAATAGAGTAGTACAGCATCCCTTGCAGCTCAAGCTTCAGGTATTCAAAACCGCCAACCGGGGTTGGGGAATTAAAGCTCTCAATGACATACCTCGAGGATGTTTCCTTTGTATATATGCTGGAAGTTTGCTCACAGATGCTGTTGCTAATGTGGACGGTGTCAACGAGGGCGATGAATTTTTGGCTGAGTTGGATTATATTGAGGTTGTTGAAAAGTTGAAAGAAAGTTATGAATCTGATGTCCCAGAAGAAGATAAAATACTCGACAAAAAGCATGATTCGAACACTTCTGATGATGACGATGATGAAGAAGATGATATTGAAAATGATAAAGCTAAAAGAGATGGACCGGCCGGAGAGTCTGATGAAGAATTTACTCCTTCGTGCTTTGTTCCGACAGATGAAGCAGGTACAAGAAGGAGTACTCGACAAAAAAAGAAGAAAACTAAATCCAAGGATAAGAAAATGGATATTCCGGTGACGGCTGCAGGAATCAATAAAGTCATCGGAGTAGAAGAAGCCATGGAGACAGACGAGCCAGTCAAAGAAAAGGTCACATCTGAGACGGAAAAATGCATTGAAGAACTCAAAGAAAAAGTTGACATTTTAAAAGTGACAAACAATGAGGACGATAAGAAAGATGATAATGTAGAGAGCGATCAAGTCAAAGATGATAAGAAACTACCGGATGATGACGCTGAAGCAAAAGAGAAAACTGCAGATGAAAAAGACAAAGACAAAATTTTCGACGTTGATGCTGAAGATGAAAAGAAACAAAAAAAAGCCGATGAAAAGGAAGCTGATGAAAAATCAGAAAAAGACAAGGCAAAAAAGAAGCCAGGAGATGACGACATGATTACAATCAGTGATGATGAAGAAGTGCGAGAACCTTCACGATTTACAGCCCCAGAAGGACTTAATGAAGATGAATATGTTCCTAAGTATAGgtcggtaagaagtctctttggacccgatgaagcttgcttcataatggacgccaaggttcaaggaaatcttggaaggtaccttaaccactcttgcaccccgaacgtgtttgtccaaaatgtattcgtagacacgcacgatcctcgcttcccttgggtcgctttcttcgccctaaatcatgtccgagctggaacggaactcacctggaactacaattacgatgtgggcagtgttccaggcaaagtgttatactgttattgcggtgcagtcacttgccgtggccgacttctCTAA
Protein Sequence
MADAPAEISKKEDELDSPSENTIADKDSDPPEKPTSSVDPVPMETDSTTDPDVAKTTGDVNTVKPEVGRDVESIESIMQFLMNSDDAAAGDPQEPCIPKEKEIDTVALNIPVSEVPDIFPEETMDTDVTSPTGTSPTAISPTKPSPTETIPTDASRAATASEENVVEKIVNAESTASVIADSTEKNTSSINDATVEKETISDSKKEKNNESESGFGDASNSTNTVDPVTRESQNATEADDASMDGIHDSELDGLLVEGNARYRGDSDQYDDEDISDDHSAEGVEGLGYRGGLGDDSNQGYGDRTSDIDDEDFVPTQDEDEDDDDDGDDDEDEDDLGNSRRRYNKKIVRRPSYQGQRPPPVKTDEDFADDENDDGISNQSVDNATDSFGNVQLQVESAVFDTDESIGGVRSPTVENNESSIAMEDVLMDVDSDSRQNGECSLDIQIVSVDGNIGIMIDKTIQENDPPVEPCVETAEALNSSVNLDCEQSESLTSTEVVTLQTPVVEAIVDIKESQLTTKLDEGMEKFSKNSVVNVHMSAEDTLLEEKASNENAELLLKSPDVTLTGPQTMDAHVPMNHEKTAEDSNATLEELNINSSVKETVEIVIEAAIPENVDASIPVEIHKPQDETMEVEQEKISESMEVDSGDKEVQDSKSQASPSKIISEINRAAKAFEDCIISSKTSTLATVDVQKHEDMETVAENEALDKNIEKAPADEIPKDLPLKSKIEDKKDTVLAKTSRLSIANEATKVTEDIVCLEETSSDSDAGTKAKELEKKIIKTEADTKPELISEESIAKPLTTAKSTPAVVKPAAGIAVPKTPATTVSPTKVTEIFSLDSDDDDVIPEVKKPEKKSHPRSTPVAKKLTAPRRSSSKKQSSGKSTTKEGDKSVSGDSADKLLVELCANPRCQSGPKGSIKLEESPSVALSLHRATQSGKLCVACLQEAIGCAERLVSGLRAGANLYKIILPHTEDLVEISSSDSETTEDQPKFLKQAAKRNKTKKSPKVDGDNQYSLTDDEMLLITGKIEKAVEDICSKFNINKHITSYEESIRQDLILLEKDAMEFELELSELQKKTDGTRNYFYDTFKPPTCAVLELSINSLIDERTGQDFHRQTIDLADDEWTPDRLGYSAKKKLSTTPEVQDVTERRSTRLRKPVNYNVDTEEALQQAALVAGLRIPNAAECEAALPPEGPEERVLVPLKVGDVMYAVRHSIFSAWVLATIMEIWPKGTMLSNGTLALFTLMTVKFEAAARGEGFVIKQVTGRQVACLKPSAFRYTIGTRVIALFKDQTQQKKKDAYYSGVIAETPSTSNIFRYLVFFDDGYAQYVKHTDAIRVCEMSLRVYEDVHADSRDFIKKYLSMYPDRAMVRMQPGQEVKVEWSGKWWASRVLAVDSSLALMRFEEGENTVVREEWIYRGNARLLPLFLELQAADRRAQGRHRAPGATSNTNKMANYPYVEYTRLDEVTTIPPMPADNVAPIIPVAVPVPISSAIPAFTPLPTAPTPLPAPPPTSQVVPSEPRAVAKKSTTHRKKDSKLEHAVTPALPQPQIPRRATPAGAMEPHSDQVRSKVVYYTPKVKVKPKKLAPHACSPNCLNKDALPLRILKTHNPLARPLLSGWERLIMKSRAKRTIMYKAPCGRRLRSPQELHLYLRLTASEMSVDLFDFDHWVHCLAEYVLTKCFVTKHDISHGVEAVPIQCVNDCDHTLPQFCAYSTRRIPTQGVDLNLDQEFLCGCDCTDDCQNKETCQCWQLTYEGARVVGYDPNRVGYQYKRLLEPVPTGIYECNSRCKCAMTCLNRVVQHPLQLKLQVFKTANRGWGIKALNDIPRGCFLCIYAGSLLTDAVANVDGVNEGDEFLAELDYIEVVEKLKESYESDVPEEDKILDKKHDSNTSDDDDDEEDDIENDKAKRDGPAGESDEEFTPSCFVPTDEAGTRRSTRQKKKKTKSKDKKMDIPVTAAGINKVIGVEEAMETDEPVKEKVTSETEKCIEELKEKVDILKVTNNEDDKKDDNVESDQVKDDKKLPDDDAEAKEKTADEKDKDKIFDVDAEDEKKQKKADEKEADEKSEKDKAKKKPGDDDMITISDDEEVREPSRFTAPEGLNEDEYVPKYRSVRSLFGPDEACFIMDAKVQGNLGRYLNHSCTPNVFVQNVFVDTHDPRFPWVAFFALNHVRAGTELTWNYNYDVGSVPGKVLYCYCGAVTCRGRLL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-