Hano004941.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Himalopsyche anomala
Gene Symbol
egg
Assembly
GCA_031772345.1
Location
CM062825.1:2581048-2613359[-]

Transcription Factor Domain

TF Family
MBD
Domain
MBD domain
PFAM
PF01429
TF Group
Unclassified Structure
Description
The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 2 0.57 2.5e+03 -1.6 0.0 28 38 1490 1509 1458 1512 0.69
2 2 9.4e-13 4.1e-09 36.2 0.0 3 71 1540 1601 1538 1606 0.87

Sequence Information

Coding Sequence
atggcTGACGTCCCTGCCGAAATTAGCAAAAAAGAAGTTGTTGTTGATTCGCTAAGTCAAAATACAACAGCGGATAAGGGTTCCGATGTTCAGGAAAAACCTACAGGTTCAGTTGAAACTGCCGCAATGGAAATAGACTCTAAAACAGATCCAGATGTTGCTAAAACAACTGTTAATGATAAAAAACCGAAAGAGGGCTGTGATGATGAAAGTATTGAAtcaattatgaattttataatgaacCCCGATGACGTGGCACCTGAAAATTCTCAAGTCCCATGTATCCCAAAGGAAAAAGAGATTGAtatggcaatactacaaatttCTGCAGCTGAAGCACCAGATATCATTCCTGAAGAAACAATGCATACTGACATTACTAGTCCGACTAAAGTCAACGAAGAAAATATTGTGGAAAAGGTCATAAATCCTGAAATTACTAGCAGTGAGATTGCAGttaatgctgaaaaaaatacaacaaacagcGATGATACCGTTGTGGAAAAAGAAACAATATCTGAttctgtaaaagaaaaaaatgacgtAAGTGAAAGTGGTTTTGGTGATGCATCGAATAGTGCAAAAATTCTGGATCCAGTCATTCCAGAAGCTCGAAACATCGCTGATGCAGATGATACATCAATGGatggTATTCATGATTCAGAATTAGATGGCCTTTTGGTGGAGGGCAGTGCCCGCTACAGGGGAGACAGTGATCAATATGATGATGAGGATAACTCTGATGATCATTCTGCTGAAGGCGGTGAAGCATTGAGCTACACAGGGGGTCTGGGTGATGATTCTAACCAAGGATACGGTGATCACGCCTCCGACATAGATGATGAAGATTTTGTTCCGACACAAGATGAAGACGAAGACGACGACGACGATGAAGATGACGACGATGACGAAGATGATTTAGGAACCGGTCGCCGccgatacaataaaaaaacagtaaggCGGCCGTCTTACCAAGGGCCCCTTGTAAAAACTGATGAAGATTTTGTTGACGATGAAAACGATGATGCTATTTCCAATCTGTCTATCGACAATGCGACCGATACTTTTGGAAATATCCAATTGGAGGTAGTGCCCGTAACCTTCGACACCGAGGAAACCATCGAAGGCATAAGTTTATCGACGGTTGAAAACGATGAATGTTCAACTGCAATGGATGTGGATTTGGATAGCCATCAGAATGGTGACTGCTCATTAGACATTCAGATAGTTTCTGTAGATGGAAATATCCGAGTTGACGCAGAAGTTGAACCGAGCGTGAAAACTGATGAAGTATTAAAATTGGATGTCAATTTAGAATATGAGGAAATTGAATCCCTCACCTCTACAGAGGTTGTGACCCTGCAAACACCTATTGATGAAGccattgaaaaaattgaagaaagTCGAGTGATAGCGGAACTCGATAAAGATGTGgcattattgaataaaacttCAGCAGATGATGTTCATTCATCAACCTGTGACACTTTACTCGAAGAGAAAGCTTCAATTGAAAATGAAGATTTACCGTTGAAATCTCCAGAAGTTACTTTAATCAGCCCTGAAACTCTAGATACAGATGTTCTGATGGGCGATGAAAAAACACCGGAATACTCCAACATCATCgtagaaaaattacaaatacataGTTCTGTTAAAGAACTCGATGAAATTATCAGTATAGCTGAAATGCCTGAAAATGTCGATGCATCATTACTTGTACAAATGCCACGTGAAGTATTGGaagtagaaaaggaaaaaattCCTGATTGCATGGAAGTCGATTCTGGAGATAAAAAAGttcaAGACTTGGAAAGTCAGGCATCgtctttgaaaattatttctgaaattaataaaaccacTAAGGCTTTTGAAGATTGCCTTCTTTCGTCTAAAACGTCTTTTCTAGCCACTGCTGATGTTCAAAAACATTTGGGCGAGGAAATGATTGTAGACAAAGTGACTCCAGAAAAAACTCATGAAAAAGCTTCCACATATGAAATTTCAAAGGATCATCTACCTCCGAAAACTAAAATAGAAGACAATAAAGATAGTGTGATAGCCAAAACTAGCAGATTAAGCATCGCTAAAGAAGTAACTAAAGTTATTGAAGATATTGTTTGTCTGGAGGAGAGTTCTTCTGATTCTGACGCCGGTACGAAAGCGAAGGAGGctgagaaaaaaattgttaaaactgaagaaaataataaatcggaaccgataaaagaaatattgccCGACCCACTTACTCCAGCAAAATCAACACCTGTAGCAGGCCTCACAGTTCCTAAAACAACTGCGACTGCATCGTCACCTCCAAAAGTGACAGAGATATTCTCATTGGATTCCGACGATGACGACGTCGTCATTCCTAAAGTCAAAAAACCTGAGAAAAAAACTCATCCGAGGTCTACGCCCGTCGCAAAAAAGCTTACTGCCCCGAGAAGGTCCTCTTCCAAGAAGCATTCATCCACTAAGTCTACTATTAAAGGAGGAGACAAAAGTGacTCTTCAATGACACCTGCATCAGTTTCAGCAGACAATGCCGACAAATTACTGATAGAACTTTGTGCCAATCCTCGTTGTCAATCAGGCCCTAAGGGAAGTATCAAACTGGAGCAGAGTCCTTCTGTGGCACTATCCCTCCATAGAGCAACGCAAAGTGGAAAACTCTGTGTTGCCTGTTTACAGGAAGCTGTTGGATGTGCTGAGCGTTTGGTATGCGGATTGCGCGAAGGCGCCAGTCTGTACAAGATTGCTCTGCCTAACACTGAAGACCTTGTTGAGATATCGTCGTCGGATTCGGAAACGACAGAAGACCAACCAAAATTCTTAAAACAGGCCGCCAGgagaaaaaagaataaaaagtcATCGAAAGTAGACAGCAAAAACCAGTATAGTTTAACGGACGATGAAATGTTACTCATAACCTGTAACATTGAAAAGGTCATGGAAGAAGTTTGCTCCAAATTTAGTATCAGCAGACACATCGCCACTTATGAAGAGTCCATCCGACAAGACTTAATATTGCTTCAGAATGATGCCATGGAGTTTGAATTAGAGCTGTCAGAATTGCAGAAGAAGACCGATTATACGAGAAATCACTTCTACGACACATTCAAACCGCCCACTTCCAGCATGCCAGAGTTGATAATCAATTCGCTAATCGATGAACGAACTGGACAGGACTTTCATAAACAGACTATCGAACTGGCTGACGATGAATGGACTCCTGACAGGCTAGGATATAGTGCAAAGAAAAAGTTGACGACTGCTCCTGAAGTTCAGgatgTCGCTGAAAGGAGGTCAACGAGAGTTCGGAAACCCGTCAATTACAATGTTGATACTGAAGAAGCTCTTCAGGATGCTTTACCACCTGAGGGTCCAGAAGAACGTGTGCTTGTCCCCTTGAAAGTTGGTGACGTTATGTATGCAGTTCGTCACTCCATCTTCAGTGCCTGGGTTCTGGCCACAATCATGGAAATATGGCCAAAAGGCACCATGCTGTCCAACGGAACACTGGCGCTGTTTACTCTAATGACGGTTAAATTTGAAGCTGCAACTAGGGGTGAAGGTTTCGTCTTGAAGCAAGTTACCGGTCGTCAGGTGGCGTGTCTGAAACCTTCTGCATTCAGATATACCATTGGCACCCGAGTAATAGCTCTCTTCAAAGATCAAACGCAACAGAAGAAAAAGGACGCTTATTATTCGGGCGTCATTGCCGAAACACCTTCACCTTCCAACATTTTCAGATATCTCGTATTCTTTGATGACGGTTATGCTCAGTACGTCAAACACACTGACGCCATAAGGGTGTGCGAGATGTCGCTGCGCGTTTATGAAGATGTCCATGCCGATTCGAgggatttcataaaaaaatatctgtccaCCTACCCCGACAGAGCCATGGTCAGAATGCAACCCGGCCAAGAAGTTAAAGTTGAATGGAGCGGAAAATGGTGGGCATCACGAGTGTTAGCCGTCGACAGTTCATTGGCATTGATGCGATTTGAAGAAGGCGAAAATACAGTTGTCCGGGAAGAATGGATATACAGAGGTAGTACCAGGCTGCTGCCACTATTCTTGGAGTTACAAGCGGCCGATAGACGAGCACAGGGCAGACACAGAGCTCCAGGGGCCACGTCCAATACCAACAAGATGGCCAACTACCCTTACGTGGAGTATACGCGTCTCGACGAAGTTACAACAGCGCCCCCGATGCGAACGGAAGATGTTACACCAATAATACCTGTAGCTGTACCGGTACCAATAGCAGCTCCGGTTCCTGCTCCAGTTACTATTCCAGTGGCAGTGCCAGCACCACCGCCGATTTCTCAAGGAGTCCAATCGACTGAGCCAAGAGCCGTCGCCAAGAAAAGCACGACCCACCGAAAGAAAGAATCTAAGGCCGAACAGCCCGTTACCCCTGCGCTTCCTCAGTCTCAGATTCCGCGGAGAGCCACTCCCGCCGGAGCTATGGAACCTCACTCTGATCAAGTTCGCAGTAAAGTTGTGTACTATACTCCGAAAGTGAAAGTTAAACCTAAAAAACTTGCACCGCATGCCTGCTCTCCCAATTGCCTCAACAAAGACGCCCTCCCTCTCAGAATTCTCAAGACTCACAATCCCCTGGCCAGGCCATTGTTATCAGGATGGGAAAGACTGATAATGAAATCCCGAGGCAAGCGTACTATTATGTACCGTGCTCCGTGTGGCAGGAGACTGAGGTCCCCTCAAGAACTTCATTTGTACTTGAGACTCACGGCCTCCGAAATGAGCGTGGATCTTTTTGACTTTGACCATTGGGTGCACTGCCTGGCTGAATACGTTCTCACCAAATGTTTTGTGACAAAACGgGATATTTCTCATGGGGTTGAAGCCGTTCCGATACAATGTGTGAATGACTGTGATCACACCCTACCTCAGTTCTGTGCGTACAGTACACGAAGGATACCAACGCAAGGTGTGGATTTGAATCTTGATCAAGAGTTTCTCTGCGGATGCGATTGCACAGATGACTGTCAGAACAAGGAGACATGTCAATGCTGGCAACTGACTTACGAAGGTGCCAGGGTTGTCGGATACGACCCCAACAGAGTGGGCTATCAGTACAAGAGACTTTTAGAGCCTGTCCCCACTGGAATTTATGAATGTAACTCTAGGTGTAAATGCGCTATGACTTGTCTGAATAGAGTAGTGCAGCATCCCTTGCAGCTCAAACTTCAGGTATTCAAGACTGTCAACCGCGGTTGGGGTATTAAAGCTCTCAATGATATCCCCCGGGGATGTTTCCTCTGTATATATGCTGGCAATTTGCTCACAGATGCTGTCGCTAATGTGGACGGCGTCAACGAGGGCGATGAATTTTTGGCTGAATTGGACTACATTGAGGTTGTTGAAAAGTTAAAGGAAAGTTATGAATCTGATGTACCAGATGAGGATAAAATACTGGACAAAAAGCATGAATCGAACACttctgatgatgatgatgatgatgacgaTGATGAAGAAAATGAAGCTGACAACAAAAGAACTAAAAAAGATGGGCCAGCCGGAGAGTCAGATGAAGAATTCACTCCTTCGTGCTTTGTTCCGCTAGATGAAGCAGGAACCAGAAGGAGTACtcgacaaaaaaagaaaaaaaacaaatccaagGACAAAAAGATGGATATTCCTGTGACAGCTGCAGGAATCAATAAAGTCATTGGAATAGAAGACCCCATGGAAACGGACGAACCAGTCAAAGACGAAGTCGAATCTGAGACAgacaaatgtattgaaaaaatcggCGTTTTGAATGTGACCAACAAAGAGGATGCTGCTGATAATGTAGAGAGCGATCAAGTCAAAGATGATAAAAAACTACCTGGCGGTACTGAAGTATCGAAAGAGAAAGCTACAGGTGAAAAAGAGAAAGACAAAATTTTCGATGTCGATGCTGAAGATGAAAAGAAACAAAAGGAAGCTGACGAAAAAACAGAAAAAGATAAACCAATCAAGAATCCAGGAGATGATGACATGATAACAATCAGTGATGATGAAGAAGCTATGAGAGAACCTTCGCGATTTACAGCACCTGAGGGACTCAATGAAGATGAATATGTTCCTAAGTATAGgTCTGTGAGAAGCCTCTTTGGGCCCGATGAGGCTTGCTTCATAATGGATGCAAAAGTTCAAGGAAATCTTGGAAGATATCTTAACcacTCCTGCACACCTAATGTGTTTGTACAAAATGTATTTGTGGACACGCACGATCCTCGCTTCCCGTGGGTCGCTTTCTTTGCCCTGAATCATGTTCGAGCGGGAACAGAACTCACCTGGAACTACAATTACGACGTGGGCAGTGTTCCAGGAAAAGTGTTATACTGCTACTGCGGCGCAGTCACTTGTCGTGGTCGACTCCTTTAA
Protein Sequence
MADVPAEISKKEVVVDSLSQNTTADKGSDVQEKPTGSVETAAMEIDSKTDPDVAKTTVNDKKPKEGCDDESIESIMNFIMNPDDVAPENSQVPCIPKEKEIDMAILQISAAEAPDIIPEETMHTDITSPTKVNEENIVEKVINPEITSSEIAVNAEKNTTNSDDTVVEKETISDSVKEKNDVSESGFGDASNSAKILDPVIPEARNIADADDTSMDGIHDSELDGLLVEGSARYRGDSDQYDDEDNSDDHSAEGGEALSYTGGLGDDSNQGYGDHASDIDDEDFVPTQDEDEDDDDDEDDDDDEDDLGTGRRRYNKKTVRRPSYQGPLVKTDEDFVDDENDDAISNLSIDNATDTFGNIQLEVVPVTFDTEETIEGISLSTVENDECSTAMDVDLDSHQNGDCSLDIQIVSVDGNIRVDAEVEPSVKTDEVLKLDVNLEYEEIESLTSTEVVTLQTPIDEAIEKIEESRVIAELDKDVALLNKTSADDVHSSTCDTLLEEKASIENEDLPLKSPEVTLISPETLDTDVLMGDEKTPEYSNIIVEKLQIHSSVKELDEIISIAEMPENVDASLLVQMPREVLEVEKEKIPDCMEVDSGDKKVQDLESQASSLKIISEINKTTKAFEDCLLSSKTSFLATADVQKHLGEEMIVDKVTPEKTHEKASTYEISKDHLPPKTKIEDNKDSVIAKTSRLSIAKEVTKVIEDIVCLEESSSDSDAGTKAKEAEKKIVKTEENNKSEPIKEILPDPLTPAKSTPVAGLTVPKTTATASSPPKVTEIFSLDSDDDDVVIPKVKKPEKKTHPRSTPVAKKLTAPRRSSSKKHSSTKSTIKGGDKSDSSMTPASVSADNADKLLIELCANPRCQSGPKGSIKLEQSPSVALSLHRATQSGKLCVACLQEAVGCAERLVCGLREGASLYKIALPNTEDLVEISSSDSETTEDQPKFLKQAARRKKNKKSSKVDSKNQYSLTDDEMLLITCNIEKVMEEVCSKFSISRHIATYEESIRQDLILLQNDAMEFELELSELQKKTDYTRNHFYDTFKPPTSSMPELIINSLIDERTGQDFHKQTIELADDEWTPDRLGYSAKKKLTTAPEVQDVAERRSTRVRKPVNYNVDTEEALQDALPPEGPEERVLVPLKVGDVMYAVRHSIFSAWVLATIMEIWPKGTMLSNGTLALFTLMTVKFEAATRGEGFVLKQVTGRQVACLKPSAFRYTIGTRVIALFKDQTQQKKKDAYYSGVIAETPSPSNIFRYLVFFDDGYAQYVKHTDAIRVCEMSLRVYEDVHADSRDFIKKYLSTYPDRAMVRMQPGQEVKVEWSGKWWASRVLAVDSSLALMRFEEGENTVVREEWIYRGSTRLLPLFLELQAADRRAQGRHRAPGATSNTNKMANYPYVEYTRLDEVTTAPPMRTEDVTPIIPVAVPVPIAAPVPAPVTIPVAVPAPPPISQGVQSTEPRAVAKKSTTHRKKESKAEQPVTPALPQSQIPRRATPAGAMEPHSDQVRSKVVYYTPKVKVKPKKLAPHACSPNCLNKDALPLRILKTHNPLARPLLSGWERLIMKSRGKRTIMYRAPCGRRLRSPQELHLYLRLTASEMSVDLFDFDHWVHCLAEYVLTKCFVTKRDISHGVEAVPIQCVNDCDHTLPQFCAYSTRRIPTQGVDLNLDQEFLCGCDCTDDCQNKETCQCWQLTYEGARVVGYDPNRVGYQYKRLLEPVPTGIYECNSRCKCAMTCLNRVVQHPLQLKLQVFKTVNRGWGIKALNDIPRGCFLCIYAGNLLTDAVANVDGVNEGDEFLAELDYIEVVEKLKESYESDVPDEDKILDKKHESNTSDDDDDDDDDEENEADNKRTKKDGPAGESDEEFTPSCFVPLDEAGTRRSTRQKKKKNKSKDKKMDIPVTAAGINKVIGIEDPMETDEPVKDEVESETDKCIEKIGVLNVTNKEDAADNVESDQVKDDKKLPGGTEVSKEKATGEKEKDKIFDVDAEDEKKQKEADEKTEKDKPIKNPGDDDMITISDDEEAMREPSRFTAPEGLNEDEYVPKYRSVRSLFGPDEACFIMDAKVQGNLGRYLNHSCTPNVFVQNVFVDTHDPRFPWVAFFALNHVRAGTELTWNYNYDVGSVPGKVLYCYCGAVTCRGRLL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-