Hano001025.1
Basic Information
- Insect
- Himalopsyche anomala
- Gene Symbol
- -
- Assembly
- GCA_031772345.1
- Location
- CM062821.1:31377013-31390957[+]
Transcription Factor Domain
- TF Family
- HMG
- Domain
- HMG_box domain
- PFAM
- PF00505
- TF Group
- Other Alpha-Helix Group
- Description
- High mobility group (HMG) box domains are involved in binding DNA, and may be involved in protein-protein interactions as well. The structure of the HMG-box domain consists of three helices in an irregular array. HMG-box domains are found in one or more copies in HMG-box proteins, which form a large, diverse family involved in the regulation of DNA-dependent processes such as transcription, replication, and strand repair, all of which require the bending and unwinding of chromatin. Many of these proteins are regulators of gene expression. HMG-box proteins are found in a variety of eukaryotic organisms, and can be broadly divided into two groups, based on sequence-dependent and sequence-independent DNA recognition; the former usually contain one HMG-box motif, while the latter can contain multiple HMG-box motifs. HMG-box domains can be found in single or multiple copies in the following protein classes: HMG1 and HMG2 non-histone components of chromatin; SRY (sex determining region Y protein) involved in differential gonadogenesis; the SOX family of transcription factors [1]; sequence-specific LEF1 (lymphoid enhancer binding factor 1) and TCF-1 (T-cell factor 1) involved in regulation of organogenesis and thymocyte differentiation [2]; structure-specific recognition protein SSRP involved in transcription and replication; MTF1 mitochondrial transcription factor; nucleolar transcription factors UBF 1/2 (upstream binding factor) involved in transcription by RNA polymerase I; Abf2 yeast ARS-binding factor [3]; yeast transcription factors lxr1, Rox1, Nhp6b and Spp41; mating type proteins (MAT) involved in the sexual reproduction of fungi [4]; and the YABBY plant-specific transcription factors.
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 5 4.4e-18 3.4e-15 56.5 1.8 1 65 117 181 117 184 0.96 2 5 0.026 20 6.0 2.0 36 64 239 267 205 270 0.68 3 5 1.5e-05 0.012 16.3 0.5 32 68 328 364 300 365 0.88 4 5 9.9 7.6e+03 -2.3 0.1 42 56 368 382 367 390 0.76 5 5 9.8e-05 0.075 13.7 4.3 32 64 456 488 439 492 0.86
Sequence Information
- Coding Sequence
- ATGTCTCCTGGAAAGAAGAAAGCTTTGGAGTTAAATAATGTCACTGGCAAAGATGATTCTCTTGCATGGCCGACTGAAGACATTAAACGACTTATAGAACGGATGCAAGATCAGATTCCTCAAAATGATCATTTCCGCCATCAAACTACCGCTGAGAATCTGGCATGGgaagagatttGCTTTGATAAATACACCAGTGATGAGTGTTATCACATGTGGAAATTGGTTCTGCAAAGAATCAGAGGTTTTCGTTTACTTCATGAAGTCCTCGTGGATGCACGCAATTGGTTAGATCGGCCATGGACAAATTATTATGGGAGCGAATCTAAGaaCCGTCATCCTGGTAAACCTAAACTACCCAGTAATGCATTTATAATTTTCTCCAAAGAAAATGGAAAAATCTTCAGGGAAGAAAATCCTAATATAAAACAGTCAGATCTCCAGAAACTTATATCTGAGGCATACCATAATTTATCTCCaaagaaaaaaggaaaatatgttaaaaaggcAGATTTAAGCAAACATGAATATgaaagaaaacttaaaatatttttAGAGGAAAACCCATTAGAAGATACATCAACGAAGACAAAAAAGAAGTCGAAAATCAACCCTACGAAAAAAGTAACagctttcaatttatattttgaaaatgaagtCAAAATCAACCCAAATTTGGTTggaaaaaaatttaaagaacaACTTTCATTTTTTCGAGGTCAATGGGAATCGTTTCCGAATTCAGAAAAGATGGTTTGGATGGAGCTTGCTGAAcgaaaacaaaaatcgatacagGAGGCATTGGAAACTGACGAGATTGAGGCTGAAGAAGTTACAAAACCAGTGTATTCAAAGAAAGAACTACTAGACTTTGATAAAGTTCACGGTAAGCCGAATAAACCGCCAGCCACAGTTTACAACCTTTTTACCAAATTGACTCTTCTATCAGGAGAATTGCAAGACTTTGAAAGCAAGGATCGTATGAAACAAGTTTCCGATAAATGGAAGTGTATAAGTTCTGAGGAAAAGCAAGAACTGACTGAGAGACTCCATTCAGAGCAGGAAGAATACAAAGCCAAATATGCAGAATTTCTTGATTCCCTTGAACCAGATGTCAGAGAACACTATGAACAACTTTCgattaccaaaaaaaaaccttcagcTAGCAAaGAACCTCAAGAAGAGGAAATCACATTGATAGAGAAGATTCAACCTGAATTAGAACGTGAAAATAATACAGATGATACTCCTCgatcCAAGAAAAAGAAACGTGCTGCAGATATTCCCGAAGAACCCAAAGAACCTCCAAGAAATGTGATGGAACATTttgctgaaatatttaaaaaaacaaacaagagTGCCACTAAAGATGAACTGACAGAAGCTTGGGATAATCTGTCAAGCAAagaacaaaagaaatataataaagagttagaaaaaactaaaaaggcgtatttgacaaattttgaaGTCTTTCTAACCTCGTTAACTCCACGTAAACTGCagaaatatttagataaataa
- Protein Sequence
- MSPGKKKALELNNVTGKDDSLAWPTEDIKRLIERMQDQIPQNDHFRHQTTAENLAWEEICFDKYTSDECYHMWKLVLQRIRGFRLLHEVLVDARNWLDRPWTNYYGSESKNRHPGKPKLPSNAFIIFSKENGKIFREENPNIKQSDLQKLISEAYHNLSPKKKGKYVKKADLSKHEYERKLKIFLEENPLEDTSTKTKKKSKINPTKKVTAFNLYFENEVKINPNLVGKKFKEQLSFFRGQWESFPNSEKMVWMELAERKQKSIQEALETDEIEAEEVTKPVYSKKELLDFDKVHGKPNKPPATVYNLFTKLTLLSGELQDFESKDRMKQVSDKWKCISSEEKQELTERLHSEQEEYKAKYAEFLDSLEPDVREHYEQLSITKKKPSASKEPQEEEITLIEKIQPELERENNTDDTPRSKKKKRAADIPEEPKEPPRNVMEHFAEIFKKTNKSATKDELTEAWDNLSSKEQKKYNKELEKTKKAYLTNFEVFLTSLTPRKLQKYLDK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -