Basic Information

Insect: Heteromyza rotundicornis
Gene Symbol: Hr39_1
Assembly: GCA_951394025.1
Location: OX596013.1:52354063-52357223[-]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 0.34 3e+03 -2.2 3.0 139 170 34 65 13 77 0.64

2 5 3 2.7e+04 -11.5 23.9 43 170 208 341 193 377 0.52

3 5 3 2.7e+04 -9.4 10.9 53 153 363 456 343 497 0.38

4 5 4.6e-16 4.1e-12 46.8 1.7 1 154 569 731 569 739 0.71

5 5 3.9e-82 3.5e-78 264.4 0.4 183 408 727 943 725 943 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	0.34	3e+03	-2.2	3.0	139	170	34	65	13	77	0.64
2	5	3	2.7e+04	-11.5	23.9	43	170	208	341	193	377	0.52
3	5	3	2.7e+04	-9.4	10.9	53	153	363	456	343	497	0.38
4	5	4.6e-16	4.1e-12	46.8	1.7	1	154	569	731	569	739	0.71
5	5	3.9e-82	3.5e-78	264.4	0.4	183	408	727	943	725	943	0.96

Sequence Information

Coding Sequence: atgtcgGCAATTAAAACGGAAAGCTCCGGTAACATAACGACAACCACAAGTGCAACGGTCACACCCTACGGAGGCGGTGTCTACCAGTTGCCTGTGAATATGAGCAGTCATGCCACGAAtgcgtcatcatcatcatcatcggccacaacaacaacaagtacgACGACCACAACCCGAAATAATATTTCGGTgacgaacataaaatgtgaagTGGACGATGTGGCAACGCCAAATGGCAACATTGTTCCAGTCATTGCCTCAACAGGATCTGGAATGGGCTACTATAATGGTGTTTTGGGAGCGACGATGAGCGGTATGGGAATGGGCGTTGGAATACGCATTCCAGTGACCAAAGCGGAAGATTCCGATTCCGAAGCGGAACTAACAAacattgaaaatttgaaagtgACGCGACGCGCTACTTCCAGTTCGGGTCCCAGTGGAAATTCCAGCAGCTACAATCATAGTAAGACCGGCCCGCGTCCCATGTCGTGGGAGGGTGAACTCTCGGAAACAGAAACGACTGAAACGGAACTGATGGAAACGGAAAACTCGCTAAGCAATGCCGATGTCGGCGTGGTGACTGTTATCAAAAGTGAAGCGACCACAACGACTCCTTCGACAGCGAGCCAAAACCAACACCAGCACCAGCCTCACCAACACcaacatcaacatcatcaccagcagcaacaacatcttcatcatcatcaacatcatctgcaacagcaacaacaacagccacacatacaacaacaaactcaACAGAACATTCAGTCAGCCTCTTCGACACTTCATCGTGATCGCGTTAAACCGGAATTGGAGCAAATCTCGGTTGAAATTCATCACAACTCTGGCGGAGCCGTAACTATGGGGGGCAACAGCATCTATGCACCGCATCAGCACCAtacgaaattgaaattggcgCCCACGCAAAGTGACCCCATTAATCTGAAGTATGAACCTTCTGATGCGACGGCCGTCAATTCGCCGCTACTCGCGCGTAATAAATCGACGACTTTGCCCCTGCCCGCCAATCCCAGTCCTGATTCTGCCATACATTCCGTTTACACACACAGCTCGCCGTCGCAATCGCCGCTCACGTCACGACACGCCCCCTATACACCGTCACTGAGTCGCAACAACAGCGACGCCTCGCACAGTTCGTGCTACTCCTACAGTTCGGAGTTCAGTCCGACACACTCGCCCATCCAAGGACGACATGCGGCACCGCCCGGTTCGGGGCCGCTTTATGGCAGCTTTAACGGTTCGCTGCATCATCCGCATTCCGTTTTGTATCGACCCATTTCGTCGGCAGAGAGTGGCACTAATATGGCGCACTCTACTCCCACCAAGGCAGAATCCGCCCAAAATCTCTCTATGGACTCGCAAACGCCGTCTCAACAACAACCATCATCTGGGTCGCTCAATATCAGCGGTGCGGATGGTTTGCCCGCCTCTGCAGCGGGCATTTCAAGGCAGCAACTCATCAACTCGCCATGCCCCATTTGTGGCGACAAAATCTCCGGCTTCCATTATGGCATCTTTTCGTGCGAGTCGTGCAAGGGCTTCTTCAAGCGCACAGTCCAGAATCGAAAGAATTACGTGTGCGTACGAGGCGGGCCCTGTCCGGTGAGCATTTCGACTCGCAAGAAGTGTCCCGCCTGTCGCTTTGAGAAATGCCTGCAGAAGGGCATGAAACTGGAGGCAATACGCGAGGATCGCACACGTGGTGGCCGCTCAACCTATCAGTGTTCGTACACGCTGCCCAACTCGATGCTGAGTCCACTGCTGAGTCCAGACCAACAGCAGAGTCCGAGTCAGCAgctgcaacagcagcagcgttTGGGGGCGGCGCACAATCACGTTGGGTCGATAGGcggtcatcatcatcatcatcagggCATGAACGGTTTCCATGCTGGTGGTGGCGGGGTGCACGTGATCAAAACCGAACAGTGTGGCGAGGCGTCTGCGAGCAATGGTAGTGGCAGCCCACTGAATGGTGGCAGCTTGGCAACGCGTGCGGGAAATATTCCAGTGCTTTTGCAGGAAATCATGGATGTTGAACACCTCTGGCAGTATAACGAAGCCGAATTGACGCGTCTCAATCAGCCGCTCTCAGCATCATCGTCCTCCTCCTCGTCCAGTACTTCAGCGTCGACCACTTCGGGCAGCACGGCCAATCAAATGACAAATCCACTGCTGGCCAGTGCGGGTCTATCGTCCAACGGCGAAAATGCAAATCCCGATTTGATTGCACACCTCTGCAATGTGGCCGATCATCGCCTCTATAAGATTGTTAAATGGTGCAAGAGTCTGCCGCTTTTTAAGAACATTTCGATCGACGATCAAATTTGCCTGCTCATCAATTCGTGGTGTGAGCTTTTACTCTTCTCCTGTTGCTATCGCTCGATCGATACACCGGGCGAGATTAAAATGTCGCAAGGCAAAAAGATTAACTTGGCGCAGGCGAAATCAAGCGGTCTTCAGGCCTGCATTGAACGAATGCTCAACCTGACCGATCACTTGAGGCGTTTGCGTATCGATCGCTATGAATATGTTGCCATGAAAGTAATTGTGCTGCTGCAATCTGACACTTCCGAGCTGCAGGAGCCGGTCAAAGTGCGCGAGTGTCAGGAGAAAGCTTTACAAAGTTTGCAAGCCTATACACTGGCCCATTATCCCGATGCGCCGTCTAAATTTGGAGAGCTACTCCTGCGTATACCAGATCTGCAAAGGACGTGCCAGcTGGGGAAGGAAATGCTCACCATAAAGTCACGTGATGGCGGTGATTTCAATTTACTCATGGAACTGCTGCGCGGAGAACATTGA
Protein Sequence: MSAIKTESSGNITTTTSATVTPYGGGVYQLPVNMSSHATNASSSSSSATTTTSTTTTTRNNISVTNIKCEVDDVATPNGNIVPVIASTGSGMGYYNGVLGATMSGMGMGVGIRIPVTKAEDSDSEAELTNIENLKVTRRATSSSGPSGNSSSYNHSKTGPRPMSWEGELSETETTETELMETENSLSNADVGVVTVIKSEATTTTPSTASQNQHQHQPHQHQHQHHHQQQQHLHHHQHHLQQQQQQPHIQQQTQQNIQSASSTLHRDRVKPELEQISVEIHHNSGGAVTMGGNSIYAPHQHHTKLKLAPTQSDPINLKYEPSDATAVNSPLLARNKSTTLPLPANPSPDSAIHSVYTHSSPSQSPLTSRHAPYTPSLSRNNSDASHSSCYSYSSEFSPTHSPIQGRHAAPPGSGPLYGSFNGSLHHPHSVLYRPISSAESGTNMAHSTPTKAESAQNLSMDSQTPSQQQPSSGSLNISGADGLPASAAGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCVRGGPCPVSISTRKKCPACRFEKCLQKGMKLEAIREDRTRGGRSTYQCSYTLPNSMLSPLLSPDQQQSPSQQLQQQQRLGAAHNHVGSIGGHHHHHQGMNGFHAGGGGVHVIKTEQCGEASASNGSGSPLNGGSLATRAGNIPVLLQEIMDVEHLWQYNEAELTRLNQPLSASSSSSSSSTSASTTSGSTANQMTNPLLASAGLSSNGENANPDLIAHLCNVADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCYRSIDTPGEIKMSQGKKINLAQAKSSGLQACIERMLNLTDHLRRLRIDRYEYVAMKVIVLLQSDTSELQEPVKVRECQEKALQSLQAYTLAHYPDAPSKFGELLLRIPDLQRTCQLGKEMLTIKSRDGGDFNLLMELLRGEH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00797808;
90% Identity: iTF_00797808;
80% Identity: iTF_00797808;