Basic Information

Gene Symbol
-
Assembly
GCA_016906905.1
Location
JAFDUZ010000012.1:8849330-8857568[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 23 0.0032 0.29 12.2 1.0 3 23 207 228 206 228 0.96
2 23 0.13 12 7.1 0.5 1 22 607 628 607 628 0.95
3 23 1 92 4.3 0.5 1 22 669 690 669 692 0.83
4 23 2.2 2e+02 3.2 0.5 3 14 703 714 702 722 0.78
5 23 7.2 6.5e+02 1.6 0.1 2 19 730 747 729 752 0.83
6 23 0.004 0.36 11.9 0.1 3 23 772 793 770 793 0.96
7 23 0.021 1.9 9.6 4.9 1 23 799 822 799 822 0.95
8 23 0.083 7.5 7.7 0.0 1 23 848 871 848 871 0.90
9 23 0.012 1.1 10.3 3.4 1 23 876 898 876 898 0.97
10 23 0.016 1.4 10.0 0.1 1 23 904 927 904 927 0.96
11 23 0.0015 0.14 13.2 1.3 1 23 940 962 940 962 0.97
12 23 0.00096 0.087 13.8 4.0 1 23 1007 1030 1007 1030 0.96
13 23 0.0018 0.16 13.0 1.7 1 23 1090 1113 1090 1113 0.96
14 23 0.00073 0.066 14.2 2.1 2 23 1136 1158 1135 1158 0.95
15 23 0.00059 0.053 14.5 0.1 2 23 1164 1186 1163 1186 0.94
16 23 0.0066 0.59 11.2 0.2 1 21 1228 1248 1228 1249 0.95
17 23 0.1 9.2 7.5 0.5 1 23 1259 1281 1259 1281 0.91
18 23 0.00018 0.016 16.2 0.4 2 23 1371 1393 1371 1393 0.93
19 23 1.2e-07 1.1e-05 26.1 1.1 3 23 1400 1420 1399 1420 0.98
20 23 0.05 4.5 8.4 0.1 1 23 1436 1459 1436 1459 0.94
21 23 0.08 7.2 7.8 0.0 1 23 1480 1502 1480 1502 0.97
22 23 0.018 1.7 9.8 0.6 1 23 1508 1531 1508 1531 0.95
23 23 0.00017 0.015 16.2 0.4 1 23 1539 1562 1539 1562 0.96

Sequence Information

Coding Sequence
ATGAATGTGAATTATGATCGTGTTTGTAGACTGTGCTTGTCATCTCAATGCGAATTACTACCGATATTTCCTACCACCAGTTCGGATGACTCGGAACCTCCTGTCCTCGCCTCGAAAATTAAAGATTGCGTGTCAGTGCAGATAAACGAAAATGACGACCTGCCAACAAATGTCTGCAGGAAATGCATTGACAATGTTAATAACTGGCACATATTTAAGTCAGTTTGTGAAAGGGCTCAAAACAAGTTACAGTCTCTGATTAATAAGGAAAGCAACCAACTAGAAGAGGTAAAAATTAAAAATGAGCCTTTATCTGATGGAGCTTATGATGATGGAGTGGTTATTGATGGATCATATCCTGACAGTGAGAATGCAGACTTATCAAGTAAAGTGCAGCCTGAAGGGCCACCTATTTTGGCTTCGTTGGGGCTCACTCCAAGAAGTGATAAGGGAATGGAGAGCGAGAAAGATGAAGACTACGAAGATGAGGAAGACATGATGGAGCAGAAAACTTTTGCAAATGTTCCTAACATGCCAGAAGTTTCTATAACAGTCATGCGACCATCAGGTGAAACTCTTCATGCACGTCAAGGTATCCAGCAGCTCGCTTCTAAGGATTGCTTAGTATGTGGCAGATCATACAGATATTCTCATAATGCAAGGCGGCATGAACTCACTGCCCATAATTTCGATAGATATACCAACAAAATTAATTCTAAAAGATCTCACACACACATGCAACCAAAACTTAGGCCCAATCCATTTAATCCAAAGGCTCGCTTAATGCCAAATCCTATAAGCCACAAAATGCAGTTTATGCCTAAATCAATGCCACCCAAAATGATGCCTCAGAAAATGATTGCACCACCGAAACCGATACCAATAAGAACAGCTAAACCTGCACAAAATAGCTTGCCTTATCCTCTTCGAATCAAAGCATTGAAAGATTTACAAATTAAGAAAAAAGAGCCCCAAATTTTGAAAACATTATTAACTGCTAAACCAGAACTCTTAGTTTCTGAACCAGAAATAATTAATTCGGGACCAGAAAGTCCAGAAACACTAATTTCGGAGCCAGAGATCGCTTCATTTCAAGTGGAAACAATTTTGTCAGAGCCTGATGGTTTTGTGCACCATCAACATGATGATGAAGAAATGGATGATGAAAACAACCAAGGGCAAAATTATGATACTGTGGACATGGACTCAGAAAATGAAATTGAAATTGCGCGGCAGCAAGAGAATGATGTCCAGGCTGATGAAAATCATGATATTAATGATGCTGAAGAGAACTCGCAAGACGATAACAATATGGAGGAGACAAACCATAACAATGAAAAAGAAAACGGTGATGACAATGGCGAAAGTCAAGATGTGGATATGGTACCTAACGTTGAAGGTGAAGGTGATGAAGATAATGCCAAAGAGAATGAAGAGAATGGAGAAAAAGAGAATGATGAACAAATCATAAACCATGATGCAAACGAAGACGACGACGACCTGCCTCCTATGAGCATAGCACCCGTCGTTGAGATTAATGAAGACATGCAAACAAACTCGTATAATAGTGATAGAAATGAGGAAGAAGAACTTGATGAAACTGTTGATCCTAATGATGCAGTTGATGGTGATGAAGCTGAAAAAGAGCTTGATCCAGATAAAGTTTATGTTACGAAAACTCAAAGAGATTTTATTCTCAAATACCGAGATATTATTGAGCAAATTAACACTAAGCGTTGCCTTTGCTGTAACAAAGAACATCCGCGTAGAAAAGCTGTTATACAACATTTACAAAAAAATGGACATAAAGTTCCTAAACATACATGTTATAATTGTGTGGTAACTTATACTCATATAGGAGCTTTACTAAGCCATATGAGATCAAACACATGTACTGATCTATGGAAAATAATTTATAATGAAAATGGCATCACGGATGACATAGTTTTAAAAGAACCCAAGGAGCTAAAGATTCAATACAAAGATATTCTTAATGCTAGATCATACCAATGTAAATTATGCCCAGCAAAATTTCAATTGAAGCAATTTATTATGAAGCATGTTCTTGATGTGCATGAAGATGGCCAATCTCGCTTCCCTAATTCTTGCGTACATTGTGGCCTGCGATTTAAAGAAAAAAGCATTGGAAAGAGACACATACGTAATGGGGATTGTACTGTCGAAATTACTTGTGAATTATGTCCTGAAAAATTCTTAAGTTTGCAAGATTTTAATGACCATGCTGTAGCTATACACGCTGGCAGCTTCGATCCTGATAATCAGAGTAAGTGTGTCGACGGTCGTCCCACGGATTGTCCTATATGCGGCAAGAAGAACAGTAGTTATCCGAATTTGGTGAAACATTTAAAAATAATACATAATGAAGAAAAGCCCCATCACTGTCAACATTGCGAACTCAAATTCGAACAAACTGCTGATCTTAACAAACATATTTACATGGAACATTCTGATAGATCCTTAGGGATGCAGACTATCGAGCCTGACATGTCTCTTGTTAAAGAAGAAGCTGAAGAGTACCATTATTCGTGTACGGAATGTAATGCGATATTCGAGACCGTCGACGCTTGGACTGATCATCAGGTAGCCGAACACAATCAAGTCGCTCACCACTGCGACCAATGCGAAAAGAAATTCTTGCGTCCATCTGAACTTGCTGAACATAAGAATACTCATTTGCGGGTGAAGTTCTATCCTTGCAGTGTTTGTTCAAACTCTTATAGTACGCCGCAAAAATTAGGCGAACATATTCAACAAGCTCATCCTGGAGCTCCCATCAGGACGCCTGGCGAATCTGAATTTTTCTGCGACATATGTATACGGTCTTTCAAAAGCCGCCAGGCCTATTCGAATCATATGCGTATACACTCCAAAGTGCCGACAACTAATAGAAAACCTGGGGAAAGTAAGAGCTTCGGACCTCAGATTATTGGTAAACCTATCCGTCACTTCCAACATGCAATGCAACCTGGATTTAGCCCTTACGTTCCGAATGCTCCTTATTGTTGCGATATTTGCGGCAAAGGATTTATGCACAAGAAAAATATATGGAAACACAAGAAGGTGCTGCACGCGGATCTCCTCAATGACAGGAATGACAGTGAAGAGAACACTATGCAAGCTTCTACAGAAGAGGATGAATATAATGTGGACGAAAATGGTGCCATTCTGTCGACTCCGCAATTTAATAGTTTTAATTTTGCAGCCTTAACAAACAATATGCATCAGGCTCCACAAGATCCCCTGCCATATTCATGTGAATTATGTTACAAAAGATTCCCTCTTAAAACGAGTCTATGGAAGCATAAACGCGCTAAGCACGGAATTATTAATGCTAGTGCAACTGGTGCTTCTGAAACTCAGACGCACGCCGGAGAAGGCAGATCTAGCTGCACCATTTGTAAAATAACTTTTTCAGACAAGAAATCTTATTATCGCCATAGGAAGAATGTCCACAAATCTACAGTTCAAATGTGCAAAATATGCGGGAAACCCCTGAATTCACCATCAGAACTTTACGAACATCTTAAAGCGGCACACGCTCGAGAATTACTGGGCTATAATCCCGGGCCGAGTAAAACCCAAGAATTAAGCCAAGAAATGGAAGCTGAGTATGATGGAGATCAAGATTCTGTTGATCCAAGTGTCGATTATCAAGCCCGTTATCCTTGTGACACATGTGGCAAACAATTTGTAGGGCTATTAGCTCTACAAAACCATCAATGTATCAATCAGATACAAAGCCAGCCGCAAACGTTCGATTGTGAAATATGTCACAAGAGCTATCTAACTATCGCTGCTCTGAAAAGCCACAGAGGGTGGCATTTACGTTCCCCCGACGGTAAAGCCGCCGCAAATAATACTGGACTTTGGATGCCACAAAATAAAGTAACCAGCAAAGTCAGCAAACACGAAGTCATAGATGCGCCTCCAGTAACACGAGTGCAAACCTCGACTCCAGCCAGCGTAGCCAAAAGAAGACTACCGCCGGAGGTTGAAGTTACCGTTGTTAATCCAAATAAAAAATTGCGATCGGACGATTCCATTGAATTAGATCACCAGAACAACTTATCTGGTGGTCCTGAAGACAGATATTGTAATCTCTGCGATAAAGAGTTCACGAAGCGTGCGGCATATCAGCGTCATATGGACGAAGTTCACCAACCGAATTCCGTTTTCTGCCCTGTCTGCGATAAGAGCTTTACTAGAAAGTCCACTTTGATCGTGCATATGAAGAAACACTACGAAGGTGGGGAAGGAAGTTCCACGCAAATGGACGATGAAGGCCACGCGTGTGAGGTCTGCGGTGCTCAATTCGAAAGTGAAAAAGCACTGGACTCGCATCGAGCTATGCAACACGGAGAAGAATCCGCTGAATCTGAAGACGATGGAAACGTCCCCATCGCTCAGCCCGGCGAGTTTACATGTGGACAATGTGGAGATGGTGTTGCCACTCCTAGGGACTTGATAGCTCATCGTACGATGCACGCCACTCCTACAAAATTCTTTTGTAATATCTGCAAGGTTTATTTCGCCCGTGCTCTAGACTTATCTTCACACACGCGAGCAAGGCACGCTGACAACGAAAAGGTATTCTTCCCTTGTGCTATGTGCGATCGTTTTTATATGAATAAGAAGAGCTTGCAACGGCACATCGAGATGGCCCACTGA
Protein Sequence
MNVNYDRVCRLCLSSQCELLPIFPTTSSDDSEPPVLASKIKDCVSVQINENDDLPTNVCRKCIDNVNNWHIFKSVCERAQNKLQSLINKESNQLEEVKIKNEPLSDGAYDDGVVIDGSYPDSENADLSSKVQPEGPPILASLGLTPRSDKGMESEKDEDYEDEEDMMEQKTFANVPNMPEVSITVMRPSGETLHARQGIQQLASKDCLVCGRSYRYSHNARRHELTAHNFDRYTNKINSKRSHTHMQPKLRPNPFNPKARLMPNPISHKMQFMPKSMPPKMMPQKMIAPPKPIPIRTAKPAQNSLPYPLRIKALKDLQIKKKEPQILKTLLTAKPELLVSEPEIINSGPESPETLISEPEIASFQVETILSEPDGFVHHQHDDEEMDDENNQGQNYDTVDMDSENEIEIARQQENDVQADENHDINDAEENSQDDNNMEETNHNNEKENGDDNGESQDVDMVPNVEGEGDEDNAKENEENGEKENDEQIINHDANEDDDDLPPMSIAPVVEINEDMQTNSYNSDRNEEEELDETVDPNDAVDGDEAEKELDPDKVYVTKTQRDFILKYRDIIEQINTKRCLCCNKEHPRRKAVIQHLQKNGHKVPKHTCYNCVVTYTHIGALLSHMRSNTCTDLWKIIYNENGITDDIVLKEPKELKIQYKDILNARSYQCKLCPAKFQLKQFIMKHVLDVHEDGQSRFPNSCVHCGLRFKEKSIGKRHIRNGDCTVEITCELCPEKFLSLQDFNDHAVAIHAGSFDPDNQSKCVDGRPTDCPICGKKNSSYPNLVKHLKIIHNEEKPHHCQHCELKFEQTADLNKHIYMEHSDRSLGMQTIEPDMSLVKEEAEEYHYSCTECNAIFETVDAWTDHQVAEHNQVAHHCDQCEKKFLRPSELAEHKNTHLRVKFYPCSVCSNSYSTPQKLGEHIQQAHPGAPIRTPGESEFFCDICIRSFKSRQAYSNHMRIHSKVPTTNRKPGESKSFGPQIIGKPIRHFQHAMQPGFSPYVPNAPYCCDICGKGFMHKKNIWKHKKVLHADLLNDRNDSEENTMQASTEEDEYNVDENGAILSTPQFNSFNFAALTNNMHQAPQDPLPYSCELCYKRFPLKTSLWKHKRAKHGIINASATGASETQTHAGEGRSSCTICKITFSDKKSYYRHRKNVHKSTVQMCKICGKPLNSPSELYEHLKAAHARELLGYNPGPSKTQELSQEMEAEYDGDQDSVDPSVDYQARYPCDTCGKQFVGLLALQNHQCINQIQSQPQTFDCEICHKSYLTIAALKSHRGWHLRSPDGKAAANNTGLWMPQNKVTSKVSKHEVIDAPPVTRVQTSTPASVAKRRLPPEVEVTVVNPNKKLRSDDSIELDHQNNLSGGPEDRYCNLCDKEFTKRAAYQRHMDEVHQPNSVFCPVCDKSFTRKSTLIVHMKKHYEGGEGSSTQMDDEGHACEVCGAQFESEKALDSHRAMQHGEESAESEDDGNVPIAQPGEFTCGQCGDGVATPRDLIAHRTMHATPTKFFCNICKVYFARALDLSSHTRARHADNEKVFFPCAMCDRFYMNKKSLQRHIEMAH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00897124;
90% Identity
-
80% Identity
-