Basic Information

Gene Symbol
-
Assembly
GCA_016906905.1
Location
JAFDUZ010000016.1:8176649-8192387[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 20 6.8e-05 0.0062 17.5 2.2 1 23 417 439 417 439 0.97
2 20 0.005 0.45 11.6 0.7 1 20 445 464 445 467 0.94
3 20 1.9e-05 0.0017 19.2 5.4 1 23 486 508 486 508 0.98
4 20 0.00016 0.014 16.3 4.7 1 23 514 536 514 536 0.99
5 20 3e-05 0.0027 18.6 5.3 1 23 542 564 542 564 0.97
6 20 2.7e-05 0.0025 18.7 7.9 1 23 570 592 570 592 0.97
7 20 6.4e-07 5.8e-05 23.8 2.9 1 23 598 620 598 620 0.97
8 20 8.7e-05 0.0078 17.1 6.7 1 23 626 648 626 648 0.97
9 20 6.2e-05 0.0056 17.6 5.6 1 23 654 676 654 676 0.98
10 20 4.2e-07 3.8e-05 24.4 1.9 1 23 682 704 682 704 0.98
11 20 4.2e-05 0.0038 18.1 7.9 1 23 710 732 710 732 0.98
12 20 6.8e-06 0.00061 20.6 6.6 1 23 738 760 738 760 0.98
13 20 9.4e-06 0.00085 20.2 5.1 1 23 766 788 766 788 0.99
14 20 3e-05 0.0027 18.6 6.4 1 23 794 816 794 816 0.97
15 20 4.3e-05 0.0039 18.1 6.1 1 23 822 844 822 844 0.97
16 20 2.8e-06 0.00025 21.8 6.2 1 23 850 872 850 872 0.98
17 20 0.00013 0.012 16.6 8.3 1 23 878 900 878 900 0.97
18 20 5.7e-07 5.1e-05 24.0 0.6 2 23 907 928 907 928 0.97
19 20 0.00062 0.056 14.4 0.3 1 23 935 957 935 957 0.96
20 20 0.022 2 9.6 5.5 1 23 966 988 966 988 0.99

Sequence Information

Coding Sequence
ATGAACCCTGAACATCATAATATTAATACGGGTGGTGGCCAGCCTCCTGGCAATTCTGAGACTCAGAACCAAAGAGTTCAACCTACACAACAACAGCAACAAGGACAAACCAATAATTTGACTCCGACAACATCTGCTACCGACTTACGAGTTAACTCAGCGGCGGTAAACGTTGCTTTGTCAAGCGTGGCTAAATACTGGGTGTTTACAAATTTATTTCCCGGTCCGCTGCCACAGGTTTCCGTATATGGATTGCCCACTGGTGCGAGAATTGAAAATGGGAAGCCTGTTCAGGATCTTGGCCAAGCCCATGCAGGCATATTGAACGGTGATCCCAACATTATATTAGGACACGCTGGACAACCCCAAGTGACTGTATCAGCAGCAGGTCAACAGATACCTGTGTCTCAAATTATTGCAAATCAAGCAACACAGGGACATGAATCGCTGGTTTCTCACGCGACAGCGGGGGAGGCAGGCGGCGGTACGACGCTGGCAGTGGCCGGCGCGGCCTCCCAGCAGGTACCCAATAATCGGGTCGAGTTTGTACAACATAACATTGATATGGTAAATCACGTGGGTCATCATTCCCAACAACATATAATGCAGCAACAGCTGATGGCAGCTACCCGTCCGGAACATTCTAATCAGCAGATTCAGCTGACGGTGAGCGAGGACGGTATCGTGACGGTGGTGGAGCCGGGCGGCGGCAAGCTGGTGGACAAGGACGAGCTGCACGACGCCATCAAGATGCCCACCGACCACACGCTCACCGTGCACCAGCTGCAGCAGATCGTCGGCCACCACCAGGTGATAGATAGTGTGGTCCGCATCGAGCAGGCGACAGGCGAGCCCGCCAACATCCTCGTAACGCAGAACCCCGACGGAACCACATCCATCGAAACAAGCGCGGCCGACCCGCTCATTGTTAAAGATGAGAAAAATGTGGCCAAAATCGAGTCCACACAGTTCGCGATACCAGCTGAGATTAAAGACATCAAAGGGATTGACTTGAAGAGTGCAATGGGCATGGAGGGAGCGGTAGTCAAAATATCAACGGGTACTGAGCATGATCTCCACGCCATGTACAAAGTCAATGTTGAGGACCTATCACAGTTATTGGCATATCATGAAGTATTTGGAAAACTTAATGCTGAAGGACAGCCACAAGCTAAGGTGATAAGCGAGGTGGAGGTGGAGGCGGGCACGAGCGCGGCGCTGGCGGAGGCGGAGTCCTCGCCCGGCCACCACTCCTGCGACATCTGCGGGAAGATCTTCCAGTTCCGATACCAGCTCATCGTACATCGACGATATCATGGTGAAAGCAAGCCATTTACGTGTCAAGTATGTGGTTCAGCCTTCGCCAATCCTGTAGAACTCTCAAAACATGGAAAATGTCACCTCGCTGGTGACCCTACGGAGCGTCAAGCGAAACGGTTAGCCCAGGACAAGCCGTACGCGTGCTCCACTTGCCATAAAACTTTTTCACGTAAAGAGCACCTTGACAACCACGTTAGGAGTCACACTGGAGAAACACCATATAGATGTCAATTCTGCGCGAAGACGTTCACTCGAAAGGAGCACATGGTGAACCACGTGCGCAAGCACACCGGCGAGACGCCGCACCGCTGCGAGATCTGCAAGAAGAGCTTCACGCGCAAGGAGCACTTCATGAACCACGTCATGTGGCACACCGGTGAAACGCCACACCATTGTCAAATGTGCGGCAAGAAGTATACTAGGAAGGAGCATTTAGTGAACCATATGAGATCACATACAAATGACACTCCGTTCAGATGCGATTTGTGCGGCAAGTCCTTCACCAGGAAGGAACACTTCACCAATCACATATTATGGCACACGGGTGAAACACCACATAGATGCGACTTCTGCTCGAAGACCTTCACTCGTAAAGAACATCTACTTAACCACGTCCGCCAGCACACGGGCGAGTCTCCCCACCGGTGCAACTTCTGCGCCAAATCGTTCACACGACGGGAGCACCTCGTCAATCATATCAGACAGCACACTGGCGAAACTCCGTTCCAATGTGGATATTGCCCTAAAGCTTTCACACGGAAAGACCACCTTGTAAATCATGTCCGTCAACACACGGGAGAGTCCCCACACAAGTGTTCCTTCTGCACGAAGTCATTCACCCGCAAGGAGCACCTCACGAACCACGTGCGCCAGCACACGGGCGAGTCGCCGCATCGCTGCACATACTGCGCGAAATCCTTCACCAGAAAAGAACACCTCACTAACCATATCAGACAGCATACGGGAGAGACTCCTTACAAGTGCACGTTTTGCACTCGCGGCTTCACGCGGAAAGAACACCTCAACCAACACATCAGACAACATACCGGCTTGTCCCCGCACACTTGTTCCTTCTGTAACAAGAGTTTCACCAGGAAAGAACATCTCGTGAACCATGTCCGGCAACACACCGGCGAGACCCCTTTCAAGTGTACATACTGCGCGAAGTCGTTCTCGCGCAAGGAGCACCTCACGAACCACGTACACCTTCACACGGGCGAGACTCCGCACAAGTGTCCCTTCTGCACCAAGACCTTCACGAGGAAAGAACATTTAACTAACCATGTTAGGGTACACACGGGCGAGTCTCCGCACCGGTGTAAAACCTGTCAAAAGACATTCACACGCAAGGAACACCTCACGAACCACGAAAAACAGCATGGTGGCGACTCGCCGAACTCTTGCAAGGTCTGCTCGAAACCGTTCACGAGGAAGGAAGACCTTATTGCACATATGAGGTCGCACAGTTGTGGGGAGCGGCCATTTAGTTGTGGAGAATGCGGCAAGTCATTCCCCTTGAAAGGAAATCTTCTATTCCATGAAAGATCACACAATAAAGGTTCAGCAAATAAATCTTTCCGGTGCGAAGTGTGCTCGAAAGAATTTATGTGTAAAGGTCATTTAGTAACACATCGACGGACGCATACTGAGGCAATTGAAAATGCAGCAAATACGGAACCAGCAGTGGAGGGAGAAGACTGTGGGGACTACGCCAAGTGTGAAAAAGATGCGCCTGAAATAGTCGAAAGGAAACATGATACGAGGTCATCAACAGAGAATATGTCAACTGAAGTTAATGTGACCCAAAATCAGGCATCTAACACGGTCATGCAAATAACAAGCCAGCAGGTTCGAGCGGGAACAACAACGAGTACAGCGAGCGTAGCTGCTGGAACGTTTACACATACCGCCAGTACTCAACACCACGCCGGTACGACTATAGCCCATCATCCGGTCACTGTGAACTACTAG
Protein Sequence
MNPEHHNINTGGGQPPGNSETQNQRVQPTQQQQQGQTNNLTPTTSATDLRVNSAAVNVALSSVAKYWVFTNLFPGPLPQVSVYGLPTGARIENGKPVQDLGQAHAGILNGDPNIILGHAGQPQVTVSAAGQQIPVSQIIANQATQGHESLVSHATAGEAGGGTTLAVAGAASQQVPNNRVEFVQHNIDMVNHVGHHSQQHIMQQQLMAATRPEHSNQQIQLTVSEDGIVTVVEPGGGKLVDKDELHDAIKMPTDHTLTVHQLQQIVGHHQVIDSVVRIEQATGEPANILVTQNPDGTTSIETSAADPLIVKDEKNVAKIESTQFAIPAEIKDIKGIDLKSAMGMEGAVVKISTGTEHDLHAMYKVNVEDLSQLLAYHEVFGKLNAEGQPQAKVISEVEVEAGTSAALAEAESSPGHHSCDICGKIFQFRYQLIVHRRYHGESKPFTCQVCGSAFANPVELSKHGKCHLAGDPTERQAKRLAQDKPYACSTCHKTFSRKEHLDNHVRSHTGETPYRCQFCAKTFTRKEHMVNHVRKHTGETPHRCEICKKSFTRKEHFMNHVMWHTGETPHHCQMCGKKYTRKEHLVNHMRSHTNDTPFRCDLCGKSFTRKEHFTNHILWHTGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCNFCAKSFTRREHLVNHIRQHTGETPFQCGYCPKAFTRKDHLVNHVRQHTGESPHKCSFCTKSFTRKEHLTNHVRQHTGESPHRCTYCAKSFTRKEHLTNHIRQHTGETPYKCTFCTRGFTRKEHLNQHIRQHTGLSPHTCSFCNKSFTRKEHLVNHVRQHTGETPFKCTYCAKSFSRKEHLTNHVHLHTGETPHKCPFCTKTFTRKEHLTNHVRVHTGESPHRCKTCQKTFTRKEHLTNHEKQHGGDSPNSCKVCSKPFTRKEDLIAHMRSHSCGERPFSCGECGKSFPLKGNLLFHERSHNKGSANKSFRCEVCSKEFMCKGHLVTHRRTHTEAIENAANTEPAVEGEDCGDYAKCEKDAPEIVERKHDTRSSTENMSTEVNVTQNQASNTVMQITSQQVRAGTTTSTASVAAGTFTHTASTQHHAGTTIAHHPVTVNY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00247403;
90% Identity
iTF_01078391;
80% Identity
-