Hcom018658.1
Basic Information
- Insect
- Hesperia comma
- Gene Symbol
- -
- Assembly
- GCA_905404135.1
- Location
- FR990012.1:34831589-34839313[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 0.00045 0.051 14.8 4.7 1 23 282 304 282 304 0.98 2 12 0.12 14 7.1 2.5 1 23 312 335 312 335 0.91 3 12 0.033 3.9 8.9 0.4 1 23 339 362 339 362 0.93 4 12 0.0078 0.9 10.9 3.5 1 23 439 461 439 461 0.99 5 12 0.06 6.9 8.1 6.1 2 23 470 492 469 492 0.96 6 12 0.53 61 5.1 4.2 1 23 496 518 496 518 0.97 7 12 0.0027 0.31 12.3 5.5 1 23 523 546 523 546 0.98 8 12 0.0072 0.83 11.0 0.9 1 23 550 573 550 573 0.95 9 12 1.1 1.2e+02 4.1 0.1 2 19 593 610 592 613 0.92 10 12 0.23 27 6.2 0.0 2 23 655 677 655 677 0.88 11 12 0.76 87 4.6 0.2 1 12 686 697 686 700 0.87 12 12 2.2 2.5e+02 3.2 0.1 1 10 711 720 711 725 0.87
Sequence Information
- Coding Sequence
- ATGAGGGATTTAAAAGCATGTGCAATATGTTTGCGAACGAGGGTTAAATTGCATAGCATGTCTGTCGGGACTTTACGAAATGATTACAACTTGATTTCAGGCCTCAAGACATCCAAAGGGAATGGATTACCTGAGTACTTATGTGTGGAATGTTCAAGCTATATAAAGAAATTCAAACGGTTTAGACAAAAATGTCATGAAGCCCATTTTGCAATGGTTGAATTGCTAAATAAAAATAAAGAGATTGATGTATCTCTATTAGAATCATTTGATTGGAAGCAAATAGGTATTACGTCTAGTCTATCATTTTTGAAATTAGATAATGTTCATTATGAAATGGTGAAATTCAAATGGGTGCAACACAATAGGCCTTTAGTTGATAAAGGAGAAAAGATACCCATACATCACTGTACTACTATTGATACTGATGTCATTTACGAAGTGCCTTTAGAGCCTGCAACAAATGTAGAAACTGAATTACTAACTACAAAAGAGGAAATAAATGAACAGAGTACACTCAATGAGTCTTCTCACATAAATGATAACAATGATTTTGATATGACAGAGCCATGTGAAGCAATAACGGATACAGTTGAAGGAGGTGACGTAGAAAAAGATGACAATATAGAAATGTTGTTTGATAGCATTTTTGGTGTGAATAGTGAAAAGGAATATGATAACTTAGGTAATGCTATTAGTAAATCTGATGAATCCAAAATCCCAGATGAAGATGAGAATGTAGATGGATCACAATTGCACGAGGAATATGCCACAATGATTCCCTTGTCTGTGCAAGAGATTAAGGCTGTTGTTGAAGTTTATAAAATGTTTGGCCAAGGAAAACATAAGTGCAGCATATGCCAGAAGGCATACCATAACGAGAACCGTTTAAAAGTTCATATGCGTATGCATGATACGCATACAAGTGGGGTATTCTACTGTTCATTATGCACTTACTACTACAAGAGTGAGTTCCTGTTGAAAACACATGTATCGGATAAGCATATGTACAAATATGTTTGCAAAAAGTGTCCAGAAGTTTCTTATGATAAGACCTCTGCAAAACAACATTATATATGGACGCATTTACAAAAAGGGAAAAAGAAGAATTCAAACTGGTATGATGCTAGTTCGAGACCAAGCTGGCTCAGTAACCGTGGTGGAAAGAGACGGAAAGGTGTCCTCGCCTTGCGTCCTGTTCGCAAGCCCAGTAGAGTGCCTAAGGACTTCCCCAAACAAAGTGCAGTGCCTCAGGAAGAACAATACCGACTAGTGCAGGAGAGAAAGCTCTCAAGGAATTATCAGGAATCAAACTTCAAGTGCCAGTTGTGCTATAGAGGGTTTAGAGAGATAACAACGTACAGCAAGCATATGAAGAAACATGATCCTGCCCATTCCGGAGAACTTCAATGTGACATGTGTAAGATGCACTTTGAGAACACGAGGAAGATGTACAAACATATGCGAATCTGTCACACTTTTAAATATACTTGTCAGATCTGCAACTTTGAAACATACAATAGGAGCTCCGCCCATATGCACTACAAATATCACAAGAATATAACGTTTAAATGTCATCATTGCGACATGGTATTCAACAAGATGTCGACCCGCCTGACGCACATCCGCGTGAAGCACCCGTCGACGTTCGTGTGCGAGCTGTGCGGCCACAGCTTCGTGAGCGACACCGGCCTCTACTACCACAAGCAGATCTCGCACACTAAGGCGGAGGTGGAGGCGAGCGCGGCGGCGGGCACGGACCCGGCGGGCGCGCTGTACTGCGCCGACTGCCGGCTGCAGTTCCGCTCGGCCCCCGCCTTCGCCACGCACTTCGGCAGCTCCGCCAACCACGCCGAGGTCAACGTGTCATCAAAACCGGTGCGAACGCCGCGCTCGGTGCGGAAGCGCGGGCGCGGCGAGGCCGCCACGGACATCGTCAACAACGGCGTGCCCACGTCCAACGTCTGCGAGATCTGCGGCGAGTCGCTGCGCAACGACGTGGCGGCGCGCAAGCACTACGAGGCCGCGCACCCCGGCGCCGACTACCTCAAGCGGTACATGTGCGACATCTGCGGACACGTCACCAAGCACTACGAGGCCGCGCACCCCGGCGCCGACTACCTCAAGCGGTACATGTGCGACATCTGCGGACACGTCACCAAGGTAACGATCACATACTGCTATATGTATGTCCGTGTGTGTGTCCGCACAACGACGTGGCGGCGCGCAAGCACTACGAGGCCGCGCACCCCGGCGCCGACTACCTCAAGCGGTACATGTGCGACATCTGCGGACACGTCACCAAGGTAA
- Protein Sequence
- MRDLKACAICLRTRVKLHSMSVGTLRNDYNLISGLKTSKGNGLPEYLCVECSSYIKKFKRFRQKCHEAHFAMVELLNKNKEIDVSLLESFDWKQIGITSSLSFLKLDNVHYEMVKFKWVQHNRPLVDKGEKIPIHHCTTIDTDVIYEVPLEPATNVETELLTTKEEINEQSTLNESSHINDNNDFDMTEPCEAITDTVEGGDVEKDDNIEMLFDSIFGVNSEKEYDNLGNAISKSDESKIPDEDENVDGSQLHEEYATMIPLSVQEIKAVVEVYKMFGQGKHKCSICQKAYHNENRLKVHMRMHDTHTSGVFYCSLCTYYYKSEFLLKTHVSDKHMYKYVCKKCPEVSYDKTSAKQHYIWTHLQKGKKKNSNWYDASSRPSWLSNRGGKRRKGVLALRPVRKPSRVPKDFPKQSAVPQEEQYRLVQERKLSRNYQESNFKCQLCYRGFREITTYSKHMKKHDPAHSGELQCDMCKMHFENTRKMYKHMRICHTFKYTCQICNFETYNRSSAHMHYKYHKNITFKCHHCDMVFNKMSTRLTHIRVKHPSTFVCELCGHSFVSDTGLYYHKQISHTKAEVEASAAAGTDPAGALYCADCRLQFRSAPAFATHFGSSANHAEVNVSSKPVRTPRSVRKRGRGEAATDIVNNGVPTSNVCEICGESLRNDVAARKHYEAAHPGADYLKRYMCDICGHVTKHYEAAHPGADYLKRYMCDICGHVTKVTITYCYMYVRVCVRTTTWRRASTTRPRTPAPTTSSGTCATSADTSPR
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01439359;
- 90% Identity
- -
- 80% Identity
- -