Basic Information

Insect: Hesperia comma
Gene Symbol: IBTK
Assembly: GCA_905404135.1
Location: FR990031.1:13079035-13095522[-]

Transcription Factor Domain

TF Family: BTB
Domain: zf-C2H2|ZBTB
PFAM: PF00651
TF Group: Zinc-Coordinating Group
Description: The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 1.7e-14 9e-12 45.9 0.0 6 79 551 623 545 630 0.90

2 3 2e-11 1.1e-08 36.0 0.0 9 107 743 845 737 848 0.82

3 3 2.3 1.3e+03 0.4 0.1 79 106 849 876 845 879 0.88

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	1.7e-14	9e-12	45.9	0.0	6	79	551	623	545	630	0.90
2	3	2e-11	1.1e-08	36.0	0.0	9	107	743	845	737	848	0.82
3	3	2.3	1.3e+03	0.4	0.1	79	106	849	876	845	879	0.88

Sequence Information

Coding Sequence: ATGAGTAAACCCATTGAGGTAGACTGCACCAGAAAGTGCAGGTCACGAAATCATGGCCAGGCCCTGACAAGTGCCATAACCAAAAGATCTGTCAGCGATGAATCCCTCGCCAGCTTCATCAAGTCAACATGTGCTAACTTTGCTAGAGCATTTGATTTTGAGGGCCGGACTGCCCTCCACATGTCGGCATCCCGTGGAAGAAACATGTTGATGGAATGGCTCGTTCGCCACTCCTCTGATGCATTTGTGAATGCGCGAGACCGGGAATCAGGGTACACACCATTGCATAGAAGTATCTTCTATGGACAGATACATTCTGCTGTTTCTTTGATGAAACTGGGAGTGAACACAGAAATTACGGACAAAGACGACTACAAAGCGTTGGAGCATGCCTTACTCGACCGTCAGTACATGTGGCAGTACACAGAAGCGGCGCCCTGCGATGCGTACGTGTGGGGAGCGAACACCAACTACACACTGGGCACTGGATCCCAGCAGTCCCGCGGGACCCCGGATCTCCTCACCTGCTTCAGTAGAACCAACGCGAACGTCAAACAGGTGTGTCTGGGCAAGTTCCACAGCATCTGGCTATGCGGCGGTACCGACGGTGGCGAGGCGTGGTGCGCTGGGCAGGCGGCGCGCGCGGGCGGCCCGCCGGCCACCGCGCTGCGGCCCGTGCCGCTCGCGCTGCCCGAGCCCTGTCTGCAGGCGGCCGTGACGCTCGGCTCGACTGTGTTCCTATTAGCGAGTGGCGCGGTGGTACAATACGCGTTAAACAACGAAAACATAAGCAGTTCTACAGCCAAGACCCCATCCACAATCAAGCTGGCAGCCACCAAGCCGCTCATCAAGCTATCAGCGCCTCTAGGGCTGCGCGCGGGCCGCTCCCACGCGGTGGTGTGGAACGCGCGCGCCGTGTACACGTGGGGCACGAACGTCGGTCAGTTGGGACACCCGCAGGAGGACAGGGTGGTGCCGGCGCCTAAGAGGGTAGCGATATCAATGAACAACAAGGAGGAGTGTACACTACAACTGGTGGACGCGGGCGACGCGGCGACCGTCGTCACGACGAGTCGTGGTGATGTGTACTTGCTGCATAGGTACATCTGCAAGAAGATCGCTGTCAAACAGATAAACCTGCGGCAAGTGTGTGTGGAAGCAAAGGTGAGCGAACAGGGGGTGTATTCTCGAGTCACGGTGCTGCTGCTCACCACTGTTGGGCAACTGCTCGTGTGGCAGGATACCACTAACCGGCTTACCAGGTGCGTCTTCGGATTGGCCCACGAAACAATAGTAACTCACGTGGCGTTAACACACGACGCTGTATACTTCACTACTAAGTTCGGCGAAGCGTACATCGGGTCTATATCACGCAAGGCCACGCCCCCCGCGCCGCAGCCGGTCAAGAAGGACAAGGACAGAGATACCAACAAGTCTGCACTAGTCAAGTTCCTAGAGAAGGACGACTGTACGTCTGTCAGGATCACCAAGATACCCAATGTTCATAGGGCGGTGTCGATTGCTGTTGATAGTGAGGGGCTGAATTTTGCTTGCTTGCAGGTTAAGCCGACTTGTGGATTGACGTCTCTGCCCGACCTGTCACCCTCAAGCTTTTCAAAACACATGGAGTCCTTGTACGAAACTGCCACAGAGGACGACATCCTACATGACGTAGTTTTTAAAGTTGGTACAAAATTGTACCCAGCGCATATATTCGTGGTTGCGTCGAGCAGTGAGCATCTATACAAGTTGTACCAGGAGGCGCGCGCAACGCCGGATGACAAGCCTATAGTTAACTTAGAGAACGTTCACCCTGAAGCATTTGAAAGGATACTGAGGTACATGTATACTGGTACCTGTGATGTAGCCGAACCAGGTCCGAATGGACTGAAGATAAGGAAGGAAGATCTGACTAATACGAAGAAAGGGAAGGATGATAACGTAGACCAGGACGCGGAAGTTATTGAGAACCCAGCCGAGATATCAGCGTTCGAGACATACAAGCATCAAGACAAGCGGCGCAACAAACGCCGCAGCACGGAGCCGCCGCGCGTGCACCTGTACTGCGACCCGGTGCGCCTCGTGCAGGCCGGTGCTAAACGACTGGGGGTTACCGGCTTGCACAGGATGCTGGATAAGTTCTACTACAGAGACGGCACGGTATACCTGAAGGAGAGCGCGGTGTACACAAAGACCTGTGTGTCGTGGGACCGCGAGTCGCTCACGGAGCTAGTGGACACTAACGTCCGGTCTAAGGACGGCGTACTGATACCCGCTCACAAGTGTGTGCTTGCAGCTAGACTCGAGTACTTCCATGGCATGTTTATGCACTCTTGGACTGAGAGCAAGTTATTATCAACAGTGACCCTACCTATAAACCACGGGATACTATTGCCCGTAATAAATTTCCTGTACACGGACTCCTGTCCAGAAGTGGAAACGTCGGACAGCATTGACTTTATATGCAGCATGTTAATCGTTTCTGACCAGTTATTCATCACTCGGCTACGAGAAATGTGTGAAGCAGCTCTAGCTAACCTTATCTCACTGAAAAACTGCACAGAATTATGTCAATTCGCACACACATATAACGCGACACAATTAAAAAAATGCTGCATGGAATTTATATCGCTAAACATATGCACAATACTAGAAAACAGAGCTTTAGATCTGCTAGAAGATGCTTTATTGGAGGACATAACGAAATACTACTGCAAATTCAATCCTATTATGTCTTCAAGAATTATCACTCCGTTTTACAACTCCCCGGATGATGCTACAATTGATGAGTGTGCAAAATCTTGCCCAGTCGACTTGGAAGTTATCGACGAAGACATGAAAAGGGATGATAGTATCACAGAGGTTCTGAAAAAGAAAAATAAAACTCCGAAAAAGATTGAGTACACTCAAAATGAAAAAGCAAGGATGCGGTATGAGTCTGTGAGCTCGGTGACGTCACTAGATTTATCCAACGAGACTCAGGGCGATGTGACGCTAGCACTTAGTTCTATATCTAAGGATGAAAAGAAATCTCCCCGTGAAAAGGATAAGTGGATTGAAGTGTCATCTGGTCAGCAGAAGCAACAAAAGATTATCCAAGCGCGGCTCAAAGCGATCACCGCTGCAAATGACATCCTCAACGAAGCACCTGTGGAGTCTTTTGTGAAGATTACGCGGAACAATTCATTTAATACAATCACCAATCAAGAAAATATTGTGCCCTCTACTTCTCGTATGTCAGTGTCTCCGCAAAGCAGCCCAATATCAGAAATGGGCAGACACACGGGCAATATTTTAATAAGTCACGTGGGGCCTAAGCTTTCACAGAAACAACGGAAGAAACTGGCCCTGCAGGGTGGTGATGCAACTCCACAGAATTTGGACAATTATTTAGCAAATAAGTTGAATGTTGGAAGTCCTCCAGATAAGCCGAAGAATGTCTGGAAGGTCTGCGAATCCCCAGTGGCTACCAGCAGCCCTAATAAGCAGAAAGCCATGGAATTCAACCAGATTTTGGCCGATCAGAAAAAGCAAAAGGACGATTCGTCGAGAATTATGACTAAACCACTAATGTTGACGCAGCTGGAAGACAAAGCGATAGAAGAACTAGAGAGATTCTATAACATACATGAGATTGACGACGAACTGATCACGGTACAACGCATCGAACTCACCGTCTCTTCGCCGCAATGGATCCACACTGCTCCTAAGTGA
Protein Sequence: MSKPIEVDCTRKCRSRNHGQALTSAITKRSVSDESLASFIKSTCANFARAFDFEGRTALHMSASRGRNMLMEWLVRHSSDAFVNARDRESGYTPLHRSIFYGQIHSAVSLMKLGVNTEITDKDDYKALEHALLDRQYMWQYTEAAPCDAYVWGANTNYTLGTGSQQSRGTPDLLTCFSRTNANVKQVCLGKFHSIWLCGGTDGGEAWCAGQAARAGGPPATALRPVPLALPEPCLQAAVTLGSTVFLLASGAVVQYALNNENISSSTAKTPSTIKLAATKPLIKLSAPLGLRAGRSHAVVWNARAVYTWGTNVGQLGHPQEDRVVPAPKRVAISMNNKEECTLQLVDAGDAATVVTTSRGDVYLLHRYICKKIAVKQINLRQVCVEAKVSEQGVYSRVTVLLLTTVGQLLVWQDTTNRLTRCVFGLAHETIVTHVALTHDAVYFTTKFGEAYIGSISRKATPPAPQPVKKDKDRDTNKSALVKFLEKDDCTSVRITKIPNVHRAVSIAVDSEGLNFACLQVKPTCGLTSLPDLSPSSFSKHMESLYETATEDDILHDVVFKVGTKLYPAHIFVVASSSEHLYKLYQEARATPDDKPIVNLENVHPEAFERILRYMYTGTCDVAEPGPNGLKIRKEDLTNTKKGKDDNVDQDAEVIENPAEISAFETYKHQDKRRNKRRSTEPPRVHLYCDPVRLVQAGAKRLGVTGLHRMLDKFYYRDGTVYLKESAVYTKTCVSWDRESLTELVDTNVRSKDGVLIPAHKCVLAARLEYFHGMFMHSWTESKLLSTVTLPINHGILLPVINFLYTDSCPEVETSDSIDFICSMLIVSDQLFITRLREMCEAALANLISLKNCTELCQFAHTYNATQLKKCCMEFISLNICTILENRALDLLEDALLEDITKYYCKFNPIMSSRIITPFYNSPDDATIDECAKSCPVDLEVIDEDMKRDDSITEVLKKKNKTPKKIEYTQNEKARMRYESVSSVTSLDLSNETQGDVTLALSSISKDEKKSPREKDKWIEVSSGQQKQQKIIQARLKAITAANDILNEAPVESFVKITRNNSFNTITNQENIVPSTSRMSVSPQSSPISEMGRHTGNILISHVGPKLSQKQRKKLALQGGDATPQNLDNYLANKLNVGSPPDKPKNVWKVCESPVATSSPNKQKAMEFNQILADQKKQKDDSSRIMTKPLMLTQLEDKAIEELERFYNIHEIDDELITVQRIELTVSSPQWIHTAPK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01082599;
90% Identity: iTF_01082599; iTF_01439166; iTF_01438165;
80% Identity: -