Hcom010487.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Hesperia comma
Gene Symbol
Hr39
Assembly
GCA_905404135.1
Location
FR990017.1:18029777-18052244[-]

Transcription Factor Domain

TF Family
SF-like
Domain
zf-C4|SF-like
PFAM
AnimalTFDB
TF Group
Zinc-Coordinating Group
Description
The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 4 1.6 2.5e+04 -5.0 6.5 118 170 256 307 154 351 0.53
2 4 6.3e-08 0.00096 19.4 0.1 1 20 432 451 432 457 0.91
3 4 0.0054 82 3.2 0.0 76 117 478 518 457 526 0.65
4 4 1.5e-61 2.3e-57 196.1 0.0 205 408 546 750 533 750 0.93

Sequence Information

Coding Sequence
ATGAACGCCGCGATGACGAGCGAGGGAGACGCGGTGAAGATTGAGGGAGGTCATGTGTCAGTCACCACCATCAGTATGGCCGGTCCAGAAGCCAGTAATGGTCAGTTCTCGTACAGTTCGAGTGGAGTGCGCATCAGTGTGTCCTCGGAACCTCACGACGAGGACTCCACTGACGCGGAAATCTCCAAAATCGACTTCACACAGCATCAATACGAGGTAAACATGCGAAATAAAAAGAAGCGCTCGTCCAGTGGGCAGTGCGACCAGAGCGAGCAGGAGCGGCCCATGTCGTGGGAGGGGGAGCTCTCCGACTCCGAGGAGATGGTCATCGACACCAGCGCCACCAACGACGAGAGCAGCCTACTAGACCTGCAGTCGTCGCGGGACTCGATCGACACGCTGCGCAACGTGACGATCAAGACGGAGCCGCTGAAGAGCGAGGGTTTCCAGAGCGACGACCAGCGCGCGCTCGAGCTCAAGTACGCGTCCACGCTGCAGTCGCATCAGCGGAGCCTCAGCATGAACAGGATATCAGTGCTGACAGACAACTCGTTGCCGCGGCGGCCAGGGTCTCCCAGTGCTAAGTCCCTGGCCCTCTCCGACCAGTACGAGCCCGCGCCGCTCGCGCAGACCGCCGAGATACAGAACCTCACTATCAAGAAGGAAACGCAGTTGTCTGAATTAAAATGTGAGCCGGCAGTGGGCATGGACAAGTTGCTGGGCCTGCACGGATCCCCACTGCTGGGCCGGCTGCCGCGGGTGCAGTCCAGTGCCAGCACAGATTCTGCTGTACACTCTATGTATACGCATAGCGTGTACAGCAGTCCGTCGGCGTCGCCGCGGCCGTCGCGGCACTACACGCCGTCGCTGTCGCGCAACAACAGCGACGCGTCGCACTCCTCCTGCTACTCCTACAGCTCCGAGTTCTCGCCCACGCACTCGCCCGTGCAGGGCCGGCACCCGCACGTGGTGTACCGCGAGGCGGCGGTGTTCCCCGCGTCGCCGGCGCACGACGAGGACGCCGACCCCGACGACCGCCTGCACCACCACCAGGGCGTCAGCCGGCAGCAGCTCATCAACAGTCCATGTCCAATCTGCGGCGACAAGATCAGCGGGTTTCACTACGGGATATTCTCATGCGAGTCGTGCAAGGGGTTCTTCAAGCGGACAGTACAGAACCGCAAGAACTACATGTGTCTGCGCGGCGGCAGTTGTCCCGTGACGGTGGCGACGCGCAAGAAGTGTCCCGCGTGTCGCTTCGACAAGTGTCTCGGGTGTGGGATGAAGTTGGAAGCGATTCGCGAGGACCGCACGCGCGGCGGACGCTCGACGTACCAGTGCTCGTACTCGCTGTCGGGCGCCGCGTCCACCGGCTCGCTGCTGGCCGCGCACGCCTCGCACGGGCCCGCGCTGCGACACGCCGCCAGCCTCAACTCGGTAAATGGTCCGTCATCATACAACAGTCGAGGGGAGTCCAGCAACAGTCGACTCACGCCGGACATACCGCCGTTATTACAGGAGATCATGGACGTAGAGCACCTGTGGCAGTACAACGAGTCGGAGCTGACGCGGCTGGGCAAGGGCGGGCCGGGGCCCAACCCGCTGCTGGCCGCGAGCGGCATCACGGCGCACAACTCCAGCGCTGATTTCCTCGCTGATCTGTGTAATATAGCTGACCATAGGCTGTATAAAATAGTCAAGTGGTGCAAGAGCTTGCCGCTGTTTAAGAATATCTCGATCGACGACCAGATCTGCCTGCTGATCAACAGCTGGTGCGAGCTGCTGGTGCTGTCGTGCTGCTACCGCGGCGTGGGCACGCCGGGCGAGGTGCGCGTGGGCGGCCCGCGCGGCATCACGCTGCACCAGAGCGCCAAATACGGGCTGACGCCGTGCATAGAGCGCATGCTGAGCTTCACCGACCACCTGCGGCGGCTGCGCGTCGACCGCTACGAGTACGTCGCGCTCAAGGTCATCGTGCTGCTCACCTCAGACGCGCCGGAGCTCCGCGAGGCGGAGAAGGTGCGCGCGTCGCAGGAGAAGGCGCTGGCGGCGCTGCAGGCGTACACCGCCGCGCACTCGCCCGACGCGCCCGCCAAGTTCGGCGAGCTGCTGCTGCGCATCCCCGAGCTGCAGCGCACCTGCCAGTTCTTCATGCAAGTCGGCAAAGAGATGCTCAATCCAGCGAACAAGGGTAAAGACGGCGAGGGGCCAAGCTTCAACCTGCTCATGGAACTACTGAGGGGGGACCACTGA
Protein Sequence
MNAAMTSEGDAVKIEGGHVSVTTISMAGPEASNGQFSYSSSGVRISVSSEPHDEDSTDAEISKIDFTQHQYEVNMRNKKKRSSSGQCDQSEQERPMSWEGELSDSEEMVIDTSATNDESSLLDLQSSRDSIDTLRNVTIKTEPLKSEGFQSDDQRALELKYASTLQSHQRSLSMNRISVLTDNSLPRRPGSPSAKSLALSDQYEPAPLAQTAEIQNLTIKKETQLSELKCEPAVGMDKLLGLHGSPLLGRLPRVQSSASTDSAVHSMYTHSVYSSPSASPRPSRHYTPSLSRNNSDASHSSCYSYSSEFSPTHSPVQGRHPHVVYREAAVFPASPAHDEDADPDDRLHHHQGVSRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYMCLRGGSCPVTVATRKKCPACRFDKCLGCGMKLEAIREDRTRGGRSTYQCSYSLSGAASTGSLLAAHASHGPALRHAASLNSVNGPSSYNSRGESSNSRLTPDIPPLLQEIMDVEHLWQYNESELTRLGKGGPGPNPLLAASGITAHNSSADFLADLCNIADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLVLSCCYRGVGTPGEVRVGGPRGITLHQSAKYGLTPCIERMLSFTDHLRRLRVDRYEYVALKVIVLLTSDAPELREAEKVRASQEKALAALQAYTAAHSPDAPAKFGELLLRIPELQRTCQFFMQVGKEMLNPANKGKDGEGPSFNLLMELLRGDH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00985246;
90% Identity
iTF_01082564;
80% Identity
iTF_00795801;