Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.11 5.1e+02 1.8 0.1 22 43 5 26 2 31 0.84

2 9 0.043 2.1e+02 3.0 0.0 21 52 32 63 21 65 0.74

3 9 0.94 4.6e+03 -1.3 0.0 21 44 107 130 99 138 0.71

4 9 0.047 2.3e+02 2.9 0.0 21 46 135 159 131 165 0.68

5 9 0.0026 13 6.9 0.0 21 46 162 187 159 192 0.90

6 9 0.0013 6.6 7.8 0.1 21 45 218 242 211 249 0.90

7 9 0.0081 39 5.4 0.0 22 46 247 271 242 277 0.85

8 9 0.031 1.5e+02 3.5 0.1 21 48 274 301 271 305 0.84

9 9 0.0022 11 7.1 0.1 21 46 302 327 298 332 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.11	5.1e+02	1.8	0.1	22	43	5	26	2	31	0.84
2	9	0.043	2.1e+02	3.0	0.0	21	52	32	63	21	65	0.74
3	9	0.94	4.6e+03	-1.3	0.0	21	44	107	130	99	138	0.71
4	9	0.047	2.3e+02	2.9	0.0	21	46	135	159	131	165	0.68
5	9	0.0026	13	6.9	0.0	21	46	162	187	159	192	0.90
6	9	0.0013	6.6	7.8	0.1	21	45	218	242	211	249	0.90
7	9	0.0081	39	5.4	0.0	22	46	247	271	242	277	0.85
8	9	0.031	1.5e+02	3.5	0.1	21	48	274	301	271	305	0.84
9	9	0.0022	11	7.1	0.1	21	46	302	327	298	332	0.90

Coding Sequence: ATGCATGCCGATGAAAAACCGTTTCAATGTGAAATTTGTTCCGTACAATTTACTTCACAAGTTGGCCTAAAAAGACATTCAATACAGCACGCCGATGAAAAACcgtttaaatgtgaaatttgttCTATAGGATTAAATTTCACTTCTAAATCAAGAATAAAACACCTCGGTGAGCATTTCAAGAAACCTTTCATAGTATGTGCTTTATGCGGAAACTTTTATacagaaaaattacattttttgaagCATCATGAGGTTCATTACGTTAAAATCAGATGCAATAATGTTAGACCACAAAAGCATCGGATTGATTATACTGataaaaaaccatttacatGTGATAATTGTCCTCTACAATTTCGATTTAAATCCGGTTTAACCAGCCATATTAAAACTCACACTGGAGAAAAGCCCATGGAATGTAAAATCTGCTTCAAACGATACTCTGAAAAGTCATTTAATaagcatttaaaaattcacACTGACGAAAAACCGTTCAAGTGTGAAATCTGTTTGAAAGTTTTTTACGAACGTAGTGACTTAACTAAGCATTTAAGAATTCACACCGGTGAAAAGTTATTCAAATGTGATGTATGTTCGCGACATTTTACTGAAAAGGCAACCTTAACCATGCATTTACGAGTCCACACTGGTGAGAAACCATTCAAATGTGATATTTGCAGTACACAATTTACTCAACGGGCAACTTTAGCTAGACATTTAAGAAACCACAGCGGAAAAAATCCATTCAAATGTGAAGTGTGTTACAAAGAATTTAATGATAAGTCAAAATTAACTAGACATGTAAAAATTCACACTGATGAAAGGCCatacaaatgtaaaatttgtCCTAAAGCTTTTTATGAACGTTCAGACTTAACTAAGCATTTAAAAGTTCACACTGGCGAAAAACCGTTTAAGTGTGAAATTTGTTGCAAACTATTTACTCAAAAGGGAAGTGTAGCCAGGCATTTAAGGATTCACACTAGTGAAAAATatgtcatttaa
Protein Sequence: MHADEKPFQCEICSVQFTSQVGLKRHSIQHADEKPFKCEICSIGLNFTSKSRIKHLGEHFKKPFIVCALCGNFYTEKLHFLKHHEVHYVKIRCNNVRPQKHRIDYTDKKPFTCDNCPLQFRFKSGLTSHIKTHTGEKPMECKICFKRYSEKSFNKHLKIHTDEKPFKCEICLKVFYERSDLTKHLRIHTGEKLFKCDVCSRHFTEKATLTMHLRVHTGEKPFKCDICSTQFTQRATLARHLRNHSGKNPFKCEVCYKEFNDKSKLTRHVKIHTDERPYKCKICPKAFYERSDLTKHLKVHTGEKPFKCEICCKLFTQKGSVARHLRIHTSEKYVI

Sequence clustering based on sequence similarity using MMseqs2