Basic Information

Insect: Hermaeophaga mercurialis
Gene Symbol: Zfy2
Assembly: GCA_951812935.1
Location: OX638360.1:50776359-50778530[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.039 4.6 8.8 0.2 1 23 139 162 139 162 0.93

2 12 0.00016 0.019 16.3 1.6 3 23 172 192 171 192 0.97

3 12 6.1e-06 0.00072 20.8 0.4 1 23 205 227 205 227 0.98

4 12 8.8e-07 0.0001 23.4 1.1 1 23 233 255 233 255 0.99

5 12 6.5e-06 0.00076 20.7 2.0 1 23 261 284 261 284 0.96

6 12 0.49 58 5.3 4.9 2 23 302 322 301 322 0.97

7 12 1.4e-05 0.0016 19.6 4.7 3 23 331 351 330 351 0.97

8 12 0.00012 0.014 16.7 0.6 1 23 357 379 357 379 0.94

9 12 1.8e-05 0.0022 19.3 2.0 1 23 385 408 385 408 0.98

10 12 1.9e-05 0.0023 19.2 0.3 1 23 435 457 435 457 0.95

11 12 7e-07 8.3e-05 23.7 0.8 1 23 463 486 463 486 0.97

12 12 5.2e-05 0.0062 17.8 5.2 1 23 492 515 492 515 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.039	4.6	8.8	0.2	1	23	139	162	139	162	0.93
2	12	0.00016	0.019	16.3	1.6	3	23	172	192	171	192	0.97
3	12	6.1e-06	0.00072	20.8	0.4	1	23	205	227	205	227	0.98
4	12	8.8e-07	0.0001	23.4	1.1	1	23	233	255	233	255	0.99
5	12	6.5e-06	0.00076	20.7	2.0	1	23	261	284	261	284	0.96
6	12	0.49	58	5.3	4.9	2	23	302	322	301	322	0.97
7	12	1.4e-05	0.0016	19.6	4.7	3	23	331	351	330	351	0.97
8	12	0.00012	0.014	16.7	0.6	1	23	357	379	357	379	0.94
9	12	1.8e-05	0.0022	19.3	2.0	1	23	385	408	385	408	0.98
10	12	1.9e-05	0.0023	19.2	0.3	1	23	435	457	435	457	0.95
11	12	7e-07	8.3e-05	23.7	0.8	1	23	463	486	463	486	0.97
12	12	5.2e-05	0.0062	17.8	5.2	1	23	492	515	492	515	0.96

Sequence Information

Coding Sequence: ATGGAAAATGGGAAAAAAACCGAAATTTGTGTggaaaatttctcaaaaatatgCAGAATATGCCTTCTTCCAAATGAGTTGATACCAATAAATTCaatagataatttaaatatttttgaaaatattacaaatatagaggtGAAAAATAATGACGGACTTCCTGAGAGTATCTGCAAAATTTGCAGCAATCttcttaaagaaattaaaatatttattgatcaGTCTAGAGATAATTATTCCATACTTAAGTTAGCACTAAATGAAACAAATGATAATAGATCGTATGATGTCATTTGTGAACCTAAATATGAACGTACAGAAAATTCTCTAATTAAAAGTGaacaaaaccaaaataaagATAATGGTTCAGAACAAGAATCAGAAACCAAACTGAAAAgtgatgaaaatgaaatatttcaatgtgCCCAATGTGATATGacatttttggttaaaaaattattaatattacatattgaagaaaaacataatacaaatctaatttctaataataactgTAAAAAGTGCAATATGGtatttgaTTCAAAAGTATTATTACTGAAACACAGAAGGTTACacaggagaaaaaaaaataaaaaagttaaaaatatcaaGTATAATTGTACTGAATGTGATCGTATTTTGACTTCACAATCAGCATTGGACAATCACATGAAAACACATACTGGAGATAGGCCTTACAAATGTTCATATTGCGATAAAAACTTTGCATTTTCTGGAAGCCTTACTGTGCATACCCGCATTCACACAGggGAAACTCCTTATCAATGCGCCATATGCAATAAAGGATATCGTAGCTCCAGCAGTCTTAAAAAACACAAGGAGAAGAAACATTTTGACTTAAAATCTTTTAATGATAAGGGTTGGAAAGATTTAGAAAAAGTACAATGCAAATTTTGCAACAAAATGCTGCACAAACACGGTTATGGCACCCATATGAGAATTCACAAGAATGAAAAGCAAGAACGTATATGTCCTTTTTGTTCTAAACATTTCAAGAAATCCTCCCACCTAGAGAGACACGTCAGGATTCATACAGGTGAACGCCCTTTTACCTGCATATTGTGTAAAAAGTCTTTTACACAGGAAGGCGACCTAAAGAGGCACTGGGCGAGCCACTCTGGTCAGAAAGAATACCAGTGTCAGCATTGTGGCAGGTTGTACTCGACAAAAAGCGCCTTGGACACCCACATTACCACAAGTCACGCCGCTGCGAAAAAATCAAACTGTGATATCTGCAAGGCAGCATGTAAATGCGATAAATTATCAACTGAACATAGATCCTTTCTGTGCACCATTTGTGGAAAATCTTTTACGGCGGGTAATAGCCTAAAAGTGCATATAAGGCTACATACAGGGGACTGTCCATTTGTCTGCACTTACTGTGGCAAAGGTTATATAAGTACCAGTAACTTGAAAAGGCATGTTATGAGAAATCACACATTGGAAAGACCTCATGTTTGTATGATATGTCACAAGGGTTTCCACGATTCTACAAATTTGAAACGCCACATTAACAGAGTGCATTCTGTGCTTGAAATAAAAGATAGAAATGAAGATACTCCCACTGTAAATGAAGCTAAAATCCAGTAA
Protein Sequence: MENGKKTEICVENFSKICRICLLPNELIPINSIDNLNIFENITNIEVKNNDGLPESICKICSNLLKEIKIFIDQSRDNYSILKLALNETNDNRSYDVICEPKYERTENSLIKSEQNQNKDNGSEQESETKLKSDENEIFQCAQCDMTFLVKKLLILHIEEKHNTNLISNNNCKKCNMVFDSKVLLLKHRRLHRRKKNKKVKNIKYNCTECDRILTSQSALDNHMKTHTGDRPYKCSYCDKNFAFSGSLTVHTRIHTGETPYQCAICNKGYRSSSSLKKHKEKKHFDLKSFNDKGWKDLEKVQCKFCNKMLHKHGYGTHMRIHKNEKQERICPFCSKHFKKSSHLERHVRIHTGERPFTCILCKKSFTQEGDLKRHWASHSGQKEYQCQHCGRLYSTKSALDTHITTSHAAAKKSNCDICKAACKCDKLSTEHRSFLCTICGKSFTAGNSLKVHIRLHTGDCPFVCTYCGKGYISTSNLKRHVMRNHTLERPHVCMICHKGFHDSTNLKRHINRVHSVLEIKDRNEDTPTVNEAKIQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00792646;
90% Identity: iTF_00792646;
80% Identity: iTF_00792646;