Basic Information

Insect: Hermaeophaga mercurialis
Gene Symbol: Hr39
Assembly: GCA_951812935.1
Location: OX638362.1:24027974-24030778[+]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 1.3e-09 1.4e-05 25.6 0.1 1 63 132 194 132 204 0.75

2 3 0.0033 37 4.5 0.0 63 118 166 220 154 233 0.67

3 3 1.7e-73 2e-69 235.9 0.2 205 408 262 460 246 460 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	1.3e-09	1.4e-05	25.6	0.1	1	63	132	194	132	204	0.75
2	3	0.0033	37	4.5	0.0	63	118	166	220	154	233	0.67
3	3	1.7e-73	2e-69	235.9	0.2	205	408	262	460	246	460	0.97

Sequence Information

Coding Sequence: ATGCCTAATATTCATGGTAGCCCCCTACACCAACACAACTTATTATACAGGAGCCTCCAGGATGAAAATTTGCAGTACACTACTGAGCAGGACAATTTAGATGAAACTGAAGATAAATCCGGAATTTTACAGGCTTCTTTACCCGCACAACCGGGAATATCCAGACAACAgcTCATTAACAGTCCTTGTCCTATATGTGGAGACAAAATCTCGGGTTTTCATTATGGCATCTTCAGTTGTGAATCGTGTAAGGGATTCTTTAAGAGAACCgtgcaaaatagaaaaaattacgTTTGTTTGAGAGGGGCTCAATGTCCAGTAACAGTTGCTACAAGGAAAAAATGTCCCGCATGCCGGTTTGAGAAATGCCTTCAGTGTGGGATGAAACTTGAAGCTATTCGGGAGGACAGAACAAGAGGTGGTAGATCGACATACCAGTGCTCTTATTCTTTGCCACCCTCCCTTACTAACCATTCTGAACTGAGAGCGAGCACCACGGATTTGAGACAAATGGGGGAAGCACATCCCGTTTTAACAGTTAAATTGGAACCACCAGACCTTCAAACCTCACATTCAAGGAGAAATATGTTCCCAGGTTCTAAAGGTGTCCCACCATTATTGCAGGAAATAATGGATGTGGAGCACCTGTGGCACTACAATGAATCCGAATTGAATAAACTGAGCACGGATGGCCACCTAGGTAAAGAAGGTTCAAGTGGGGCAGTTCATAACTTGTCAACGCATCCTTTGTTGGCCGGTACAGCGCTGGCGGGATCAGCGGATACGAATCCTGATTTCGTAGCGAATTTGTGCAATATTGCCGATCATAGGCTATACAAAATTGTTAAGTGGTGCAAAAGCCttcctttgtttaaaaatatttcgaTTGACGACCAAATATGTCTACTTATTAATTCGTGGTGTGAGTTGCTCCTTTTTTCCTGTTGTTTCCGATCGATGGTTAGCCCGGGAGAGATAAGAATATCTTTAGGGAAGAGTATAACTCTTGCACAAGCTAGAGAAATGGGCATGCAAGCTTGTATAGAAAGAATGTTGAATTTTACTGAACAACTTAGAAGATTAAGAGTAGACCAATATGAGTACATTGCAATGAAAGTTATTGTTCTTTTAACTTCAGATACGTCGGAGCTGAGGGAAGCTGAAAAGGTGAGATTATCTCAAGAAAAAGCTCTTAAAGCTCTACAAGATTACACATTATCACATTACCCAGAAAGTCCCTCTAAATTTGGCGAATTACTTTTACGAATTCCAGAATTACAACGAACTTGCCAAgtaggGAAAGAGATGTTGACAATAAAATCGAAAGATGGAGATGGACCCAGTTTCAACCTCCTAATGGAGCTCCTTCGGGGGGACCACTGA
Protein Sequence: MPNIHGSPLHQHNLLYRSLQDENLQYTTEQDNLDETEDKSGILQASLPAQPGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCLRGAQCPVTVATRKKCPACRFEKCLQCGMKLEAIREDRTRGGRSTYQCSYSLPPSLTNHSELRASTTDLRQMGEAHPVLTVKLEPPDLQTSHSRRNMFPGSKGVPPLLQEIMDVEHLWHYNESELNKLSTDGHLGKEGSSGAVHNLSTHPLLAGTALAGSADTNPDFVANLCNIADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSMVSPGEIRISLGKSITLAQAREMGMQACIERMLNFTEQLRRLRVDQYEYIAMKVIVLLTSDTSELREAEKVRLSQEKALKALQDYTLSHYPESPSKFGELLLRIPELQRTCQVGKEMLTIKSKDGDGPSFNLLMELLRGDH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01296227;
90% Identity: iTF_01047319;
80% Identity: iTF_00792280;