Basic Information

Insect: Hemithea aestivaria
Gene Symbol: POLA2
Assembly: GCA_947507615.1
Location: OX382344.1:6654284-6675191[+]

Transcription Factor Domain

TF Family: zf-LITAF-like
Domain: zf-LITAF-like domain
PFAM: PF10601
TF Group: Zinc-Coordinating Group
Description: Members of this family display a conserved zinc ribbon structure [3] with the motif C-XX-C- separated from the more C-terminal HX-C(P)X-C-X4-G-R motif by a variable region of usually 25-30 (hydrophobic) residues. Although it belongs to one of the zinc finger's fold groups (zinc ribbon), this particular domain was first identified in LPS-induced tumour necrosis alpha factor (LITAF) which is produced in mammalian cells after being challenged with lipopolysaccharide (LPS)[2]. The hydrophobic region probably inserts into the membrane rather than traversing it. Such an insertion brings together the N- and C-terminal C-XX-C motifs to form a compact Zn2+-binding structure [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 0.0018 4.6 8.1 0.1 27 67 505 545 490 548 0.75

2 5 0.0018 4.5 8.1 0.1 27 67 560 600 545 603 0.75

3 5 0.0018 4.5 8.1 0.1 27 67 615 655 600 658 0.75

4 5 0.0018 4.5 8.1 0.1 27 67 670 710 655 713 0.75

5 5 0.0018 4.5 8.1 0.1 27 67 725 765 710 768 0.75

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	0.0018	4.6	8.1	0.1	27	67	505	545	490	548	0.75
2	5	0.0018	4.5	8.1	0.1	27	67	560	600	545	603	0.75
3	5	0.0018	4.5	8.1	0.1	27	67	615	655	600	658	0.75
4	5	0.0018	4.5	8.1	0.1	27	67	670	710	655	713	0.75
5	5	0.0018	4.5	8.1	0.1	27	67	725	765	710	768	0.75

Sequence Information

Coding Sequence: ATGGCTTCCGAAGAGTTGGTGACTGAGCAATTTCAATTTTTGGGGATTGAAGTGCAAAAAGAAGTATTATCAAAATGTGTAAGTTTGTGCGAAGAGTACGATATCGACGCCGAATCCTTCATCGAACAATGGATGGCATTCAGCTTAAATCATTTAAATGGCGCATCACCAGACTTGAACAATTTGGACATATTCGCTAGAAAGGAATTTTCCAAGCGCGCAGCCAATCGACACAACGCTCCCTCAAAAGATACCGTCGCCGGCGCAGGATTGACTGTGTACGGAGCGCCGGCTTCAATACAATCTGACAATGAAGTCCTTTCAAATTACATGGCTGCTACACCAAAGAGAGTTAAAGTAGAAATTGAAACCAGCAATCAAAACGAATTATGCCCAGCTACATATTCGCCTACTATTGCATCAGCAAAATACGCGTCAAGAGCAAACGCCGGCTCCGTGGTGCATTCATACGGAGATGAGAAACTACTGAAGATTATATCAGATCCAAACGGAGCTAACAGTTTATTGAACCTTAGAATAACACAAGTGCCTAATGACGATGGTGATACTTATAATAAAGCTATGTTCGGATTTGAGCTGCTACATGAAAAAGCCAGTATATTTGACAACCACATACGATATTTATCACAGTGTATTATGAAGAAAGCTGGTATCACAGAATCTACTTCAGTGAGGCACAAAACACAGACAGAAGTATCAGTGGCCGGTCGAATAGAGTGCGACGCGGACGCCAGACTCAACCCCAAGAGCGTAGTGCTGCAGGGAACTTGGGAACAATCGCTCAGCCAAACTGTGCCTGTTGATCTTGACAACCTGAAGCAATACTCGTTGTTCCCGGGACAAGTGGTAGTGATGCGCGGTGTGAACCCGCGCGGGGACAGGTTCATAGCCCACGAGGTGCTCGCCGACGCTGCGTTACCGCTCGCTGGCTATAACGACGATATCATGAATACTTTGACAGGCACAATATCAATGGTGATAGCATCCGGTCCATACACAACCTCAGACAACATGGCGTATGAACCACTCAAAGATCTAGTTACATACATCAACACACACAAACCGCATATGCTCTTAATGACCGGTCCGTTCATGGACAGTGAGCATTCCAAGGTTAAAGACTGCACCATGGCCGAGACTTTCAGGTCCTTCTTTGACAAGTTGGTTGACAGTTTGGGCGAGTTGAACACGACTTGCCCCTACACAAAAGTCTACATAATATCGAATCTCAAGGACGCATTCCACGTGAACATATACCCTACACCACCGTACCTCAGCCGAAGGAAACATTCGAACATACACTTCATGCCGGATCCATGCACTATCAACGTTAACGGAGTTATGGTGGGAGTTACCAGCTCTGACATCTTGATGGCTATCAGCCAGGAGGAGATTTCATCAGGCATGTCTGGCGACAAGTTGTCCCGGCTGGCGTCTCACATCATTCAGCAGCAGTCGTACTGGCCGGTGCACACTACGCCCGCACCCGACGCAGCGCTGTGGGCCGCGCACGCACAACTGACGACCACGCCCAGGGTTGTCGTACTACCCTCCAACTTCAGATATTTTGTTAAGGTAAGGTACTATTGCTCTAATTGTATTCACATCATTCAGCAACAGTCGTACTGGCCGGTGCACACTACGCCCGCACCCGACGCAGCGCTGTGGGCCGCGCACGCACAACTGACGACCACGCCCAGGGTTGTCGTACTACCCTCCAACTTCAGATATTTTGTTAAGGTAAGGTACTATTGCTCTAATTGTATTCACATCATTCAGCAACAGTCGTACTGGCCGGTGCACACTACGCCCGCACCCGACGCAGCGCTGTGGGCCGCGCACGCACAACTGACGACCACGCCCAGGGTTGTCGTACTACCCTCCAACTTCAGATATTTTGTTAAGGTAAGGTACTATTGCTCTAATTGTATTCACATCATTCAGCAACAGTCGTACTGGCCGGTGCACACTACGCCCGCACCCGACGCAGCGCTGTGGGCCGCGCACGCACAACTGACGACCACGCCCAGGGTTGTCGTACTACCCTCCAACTTCAGATATTTTGTTAAGGTAAGGTACTATTGCTCTAATTGTATTCACATCATTCAGCAACAGTCGTACTGGCCGGTGCACACTACGCCCGCACCCGACGCAGCGCTGTGGGCCGCGCACGCACAACTGACGACCACGCCCAGGGTTGTCGTACTACCCTCCAACTTCAGATATTTTGTTAAGGTAAGGTACTATTGCTCTAATTGTATTCACATCATTCAGCAACAGTCGTACTGGCCGGTGCACACTACGCCCGCACCCGACGCAGCGCTGTGGGCCGCGCACGCACAACTGACGACCACGCCCAGGGTTGTCGTACTACCCTCCAACTTCAGATATTTTGTTAAGGAAGTGAACGGGTGCGTGGTTATAAACCCCGAGCATCTCACAAAAGGAACTGGCGGCGGTACATTCGCACGAGCTCTTATCTCCGCTGACAAGGAACACTTGAATATCGCCGCGCAGATTGTACGCATTTAG
Protein Sequence: MASEELVTEQFQFLGIEVQKEVLSKCVSLCEEYDIDAESFIEQWMAFSLNHLNGASPDLNNLDIFARKEFSKRAANRHNAPSKDTVAGAGLTVYGAPASIQSDNEVLSNYMAATPKRVKVEIETSNQNELCPATYSPTIASAKYASRANAGSVVHSYGDEKLLKIISDPNGANSLLNLRITQVPNDDGDTYNKAMFGFELLHEKASIFDNHIRYLSQCIMKKAGITESTSVRHKTQTEVSVAGRIECDADARLNPKSVVLQGTWEQSLSQTVPVDLDNLKQYSLFPGQVVVMRGVNPRGDRFIAHEVLADAALPLAGYNDDIMNTLTGTISMVIASGPYTTSDNMAYEPLKDLVTYINTHKPHMLLMTGPFMDSEHSKVKDCTMAETFRSFFDKLVDSLGELNTTCPYTKVYIISNLKDAFHVNIYPTPPYLSRRKHSNIHFMPDPCTINVNGVMVGVTSSDILMAISQEEISSGMSGDKLSRLASHIIQQQSYWPVHTTPAPDAALWAAHAQLTTTPRVVVLPSNFRYFVKVRYYCSNCIHIIQQQSYWPVHTTPAPDAALWAAHAQLTTTPRVVVLPSNFRYFVKVRYYCSNCIHIIQQQSYWPVHTTPAPDAALWAAHAQLTTTPRVVVLPSNFRYFVKVRYYCSNCIHIIQQQSYWPVHTTPAPDAALWAAHAQLTTTPRVVVLPSNFRYFVKVRYYCSNCIHIIQQQSYWPVHTTPAPDAALWAAHAQLTTTPRVVVLPSNFRYFVKVRYYCSNCIHIIQQQSYWPVHTTPAPDAALWAAHAQLTTTPRVVVLPSNFRYFVKEVNGCVVINPEHLTKGTGGGTFARALISADKEHLNIAAQIVRI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -