Basic Information

Insect: Helicoverpa zea
Gene Symbol: Zfa
Assembly: GCA_002150865.1
Location: KZ118777.1:85136-95635[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 23 0.0045 0.31 11.6 1.5 3 23 204 225 203 225 0.96

2 23 0.13 9.3 7.0 0.3 1 22 626 647 626 647 0.95

3 23 4.7 3.3e+02 2.1 0.4 1 22 689 710 689 712 0.82

4 23 0.01 0.73 10.5 4.8 2 22 722 742 721 742 0.93

5 23 5.7 4e+02 1.9 0.0 3 23 751 772 749 772 0.89

6 23 0.0083 0.58 10.8 0.2 3 23 793 814 791 814 0.96

7 23 0.0024 0.17 12.5 3.5 1 23 820 843 820 843 0.95

8 23 0.08 5.6 7.7 0.0 1 23 869 892 869 892 0.90

9 23 0.012 0.84 10.3 3.4 1 23 897 919 897 919 0.97

10 23 0.0052 0.37 11.4 0.1 1 23 925 948 925 948 0.95

11 23 0.0015 0.1 13.2 1.3 1 23 961 983 961 983 0.97

12 23 0.00011 0.0079 16.7 1.8 1 23 1033 1056 1033 1056 0.97

13 23 0.003 0.21 12.2 1.7 1 23 1115 1138 1115 1138 0.96

14 23 0.00074 0.052 14.1 1.5 2 23 1165 1187 1164 1187 0.96

15 23 0.025 1.8 9.3 0.1 2 23 1193 1215 1192 1215 0.94

16 23 0.0061 0.43 11.2 0.2 1 21 1259 1279 1259 1280 0.95

17 23 0.00027 0.019 15.5 1.0 1 23 1290 1312 1290 1312 0.93

18 23 7.1e-05 0.005 17.3 0.3 2 23 1405 1427 1405 1427 0.93

19 23 2.5e-07 1.8e-05 25.0 1.4 3 23 1434 1454 1433 1454 0.98

20 23 0.019 1.3 9.7 0.4 1 23 1472 1494 1472 1495 0.95

21 23 0.12 8.3 7.2 0.0 1 23 1518 1540 1518 1540 0.97

22 23 0.017 1.2 9.8 0.6 1 23 1546 1569 1546 1569 0.95

23 23 0.00016 0.011 16.2 0.4 1 23 1577 1600 1577 1600 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	23	0.0045	0.31	11.6	1.5	3	23	204	225	203	225	0.96
2	23	0.13	9.3	7.0	0.3	1	22	626	647	626	647	0.95
3	23	4.7	3.3e+02	2.1	0.4	1	22	689	710	689	712	0.82
4	23	0.01	0.73	10.5	4.8	2	22	722	742	721	742	0.93
5	23	5.7	4e+02	1.9	0.0	3	23	751	772	749	772	0.89
6	23	0.0083	0.58	10.8	0.2	3	23	793	814	791	814	0.96
7	23	0.0024	0.17	12.5	3.5	1	23	820	843	820	843	0.95
8	23	0.08	5.6	7.7	0.0	1	23	869	892	869	892	0.90
9	23	0.012	0.84	10.3	3.4	1	23	897	919	897	919	0.97
10	23	0.0052	0.37	11.4	0.1	1	23	925	948	925	948	0.95
11	23	0.0015	0.1	13.2	1.3	1	23	961	983	961	983	0.97
12	23	0.00011	0.0079	16.7	1.8	1	23	1033	1056	1033	1056	0.97
13	23	0.003	0.21	12.2	1.7	1	23	1115	1138	1115	1138	0.96
14	23	0.00074	0.052	14.1	1.5	2	23	1165	1187	1164	1187	0.96
15	23	0.025	1.8	9.3	0.1	2	23	1193	1215	1192	1215	0.94
16	23	0.0061	0.43	11.2	0.2	1	21	1259	1279	1259	1280	0.95
17	23	0.00027	0.019	15.5	1.0	1	23	1290	1312	1290	1312	0.93
18	23	7.1e-05	0.005	17.3	0.3	2	23	1405	1427	1405	1427	0.93
19	23	2.5e-07	1.8e-05	25.0	1.4	3	23	1434	1454	1433	1454	0.98
20	23	0.019	1.3	9.7	0.4	1	23	1472	1494	1472	1495	0.95
21	23	0.12	8.3	7.2	0.0	1	23	1518	1540	1518	1540	0.97
22	23	0.017	1.2	9.8	0.6	1	23	1546	1569	1546	1569	0.95
23	23	0.00016	0.011	16.2	0.4	1	23	1577	1600	1577	1600	0.96

Sequence Information

Coding Sequence: ATGAATGTGAACTATGATCGTGTTTGTAGACTGTGCTTGTCATCTCGAGGCGAATTACTGCCGATTTTTCCTACCACCAGTTCGGATGACTCGGAACCTCCCGTCCTCGCTTCTAAAATCAAGGATTGTGTGTCCATACAGATAAACGAAAATGACGACCTGCCCACTAATGTCTGCAGGAAATGCATGGACAATGTCAACAACTGgcatgtatttaaaaatgtatgtgaaaggacacaaaacaaactACAGTCTCTAAAAGATGGCAGCCAACTAGAAGAGgtgaaaataaaaagtgaacCACTATCTGATGAGGCTTATGATGATGGAGTGGTCATTGATGGCTCATATCCTGTCATTGAGaatgCTGGCTTGTCAAACAAAGTGCAGCCTGAAGGTCCCCCAATCTTGGCTTCATTGGGGCTCACACCAAGAAGTGATAAGGGGGCGGAAAGTGAAAACAATGAAGAAGAAGAGGAAGAAATGAATGAGCCCGCACAAAGTTATCCAAAAGTGCCACACATGCCGGAGGTTTCTATCACAGTAATGCGGCCCACCGGCGAGACGCTGCACGCGAGGCAGGGCATCCACCAGCTCGCGTCCAAGGACTGCCTCGTCTGCGGCCGCTCCTACAGGTACTCGCACAACGCCCGCCGACATGAACTCACCTCGCACAGCTTCGACAGGTACACAAACAAAATCACTCCTAAGAAAACTCTCACTCACCTACAACCAAAACTCAGACCGAATCCGTTTAACCCCAAAGCACGGATGATGCCGAATCCTATTAGTCATAAGATGCAATTCATGAATAAGAACATCCCAGCGAAAATTATGCCCATCAATAAAGTTGTAACGCCACAAAGACCTATTCCAATCAAAACGTCCAAGGCCTCGCAAAATAACTTACCATATCCACTGCGTATTAAAGCACTCAAAGatttgcaaataaagaaaaaggaaCCTCAGATCCTAAAGACTTTGTTGACCTCTAAACCTGAAGTACTAGTATCAGAACCTGAAATCTTAAATTCTGGACCTGAAAGTCCAGAAACGTTGATATCTGAACCTGAGATTGCGTCATTTCAAGTCGAGGCTATTCTCACTGAACCTGACGCCGAAGCTATTATACCTGACGTCGATGGATACGATCACCAGCAAGGTGACGAAGAAGGTGATGAAGAAATGCATAACAATCAGAATCAACATTATGACACGGTTGACATGGACTCAGATAACGAAATCGAGATTGCTCGCCAAGAAGGCGAACAAGAAGGTGAACAAGAAGGTGATGATAACGCTGACGGCGACGAAAATGTTGACCAGTGTGAAGATGATAATAATATGGAAGGTGCTCAAAGCGATAACGAGAAAGATGTCAACGATGACACTGTAGAAAGCCAAGAACATATGGAAGAAGATGACAGTCTTGATATTAAACCTGACGGAGACATGAAGGACGATGACGGCCAGGAAGAGAGAGAACATGAAGACGGAGAACACGATGAAGAAGGTGAGATGAATCATAACGATGTCGAGGAGGAAGAAGACGATGACCTTCCAATGACATTGGCCCCAGTCGTCGAAATAAATGAGGGCTTACAAACTAATTCATTTAACAGCGAAGTTAATGAAGATGACGAGGAACTGGACGAAACAGCTGATCCTAATGATACCATTGACGACGACGACCAGGTGAAAGAACTTGACCCTGACAAAACTTATGTTACTAAAACCCAAAGAGATTTCATCCAAAAATATCGCGACATCATTCAGCAAATTAACACAAAGCGTTGTTTGTGCTGTGATCGGGAGCATCCCCGCAGAAAAGCAGTCATACAACACTTGCAGAAAAACGGACACAAAGTACCAAAACACACTTGTTACAACTGTGTCATCACATTTGGCCACATTGGCGCTTTACTCAGCCATATGAGGTCAAATTCTTGTACCAATTTgtggaaaattatttacaacgAAAATGGCATTACTGATGACTTAGTTCTTGAAGATGAACCGAAAGAAGTCAAGGTTCAATACAAAGATATTTTCAATGCCAGATCATACGCGTGCAAGCTGTGCCCGGCTAAGTTCCAACTTAAACAGTTTATCATGAAGCATGTATTGGATACACATGAGGACGGACAGTCAAGAGTGCCTCTCTGTTGTGTTCACTGCCGTTCTAGATTCAAAGATAAAAGTTTACTCAAAAAACACATTCGTAAAGGTGAATGTACGGTTTATATAGCTTGCGATCTGTGTGCAGAAAGGTTCGGGAATATGCAAGACTTTAATGATCACGCTTTAGCTGTCCACGCTGGCAGTTTCGATCAGTCGGATAATCAAAGCAAATGTGTTGACGGTCGACCAACTGACTGTCCATTATGTGGAAAGAAAAACAGCAACTATCCGAATTTAGTGAAACATTTGAAGATTATACATAGTGAGGAGAAACCTCATTACTGCCAGCATTGCGACTCTAAATTCGAACAAGCTACTGATCTGAACAAACACATTTACATGGAGCATTCTGACCGAACTTTAGGCATGGCCAGCTCTGAGCCGGATATGTCCATTGTGAAGGAAGAAGCTGAAGAATATCATTACTCGTGTACTGAATGCAATGCCATATTCGAAACTGTGGACGCGTGGACTGATCACCAGGTCGCGGAACATAACCAAGTGGCCCACCATTGTGACCAGTGTGAGAAGAAATTCCTTCGTCCGTCAGAGCTCGCGGAGCATAAGAATACTCATTTGAGGGTTAAATTCTATCCATGCAGTGTCTGCCCCAACTCTTACAGCACTCCACAGAAACTGTCTGAGCATGTTCAGCAGGCACATGCGGGAATCGGCGCAGTCGCAGCTACTGAATCTGAGTTTTTCTGCGATATTTGCATCAGATCATTCAAAAGTCGCCAAGCATACTCCAACCATATGCGTATTCATGCTAAAATACCAACCACAAACAGGAAACCAGGCGTTATTAAAGGCGGGTTTGCACCACAAATCATAGGAAAACCCATTAAACAATACCCTGTAGTTCAACCTGGGTTCGTATCATTTAAGCCTAATTACAATATACCTAACGCTCCCTACTCATGTGACATTTGCGGCAAAGGATTCATGCATAAGAAGAATATTTGGAAACATAAGAAAGTATTGCATGCAGACATTTTAGTTGATAGACATGATAGTGAAGAGAACACTATGCAAGCTTCGACTGAAGAGGAAGAATTCAATCCTGATGAGAACGGTGCGGTCCTCTCAACACCgcaatttaatagttttaacttCTCAAATTTTCCGAACAATGCGCAACAAGCGTCACCAGCAACGCCTTACTCGTGTGAATTGTGTTTTAAACGATTCCCACTCAGGACTAGTTTGTGGAAACACAAGCGCGCTAAACACGGATTTGTAAATCCTAGCACAAGTGGTAGCAACGATACATCAACAGCATCGGCCAGTGGAGACACTAGCAGTAGATCTAGCTGCACGATATGTAGGATCACGTTTGCGGACAAAAAATCTTACTACCGACACCGTAAGACTGTCCACAAATCCACCGTtcaaatgtgtaaaatatgtgGCAAACCTCTAAGTTCAACGTTGGAATTGTACGAGCATTTGAAGGCCGCACACGCAAGAGAATTACTGGGTTATAACGCCAACCAAGGATCAAGTAAATCTCAAGAAATGAAACAAGAGATTGAACCTGATTATGAAAATGATCAGGAGTCGGCAGATCCCAGCGTAGATTATCAAGCGAGATACCCTTGTGACACATGTGGTAAACAATTTGTTGGTTTGCTTGCTTTGCAAAATCACCAGTGCGTCAACCAGATACCAGCACAACCACAGACGTTCGACTGCGAGATTTGTCATAAAAGTTACACTTCAATATCAGCACTAAAAAGCCATCGCGGTTGGCATCTACGTTCACCTGATGGGAAAGCGGCCGCTAATAATTCTGGGCTTTGGATGCCTCAGCACAAAGTTACTAGCAAGATAAGTAAACATGAAGTCGTGGACCCAACGCAACTAGCTAAGGTCACGCATACCCCTGCACCCCCACCAGTGTCGGCCTCCGCAGCGAAAAGAAGACTACCGCCGGAGGTCGAAGTAACCGTTGTTAATCCAAACAAGAAATTACGATCAGACGATTCCGTCGATATGGATATGCAAAATTCAGGTTCTATGGAGGATAGATACTGTACGATATGCGACAAGGAGTTCACAAAACGAGCGGCTTATCAACGCCACATGGACGAAGTGCACCAACCGAACTCCGTGTTTTGCCCGGTCTGTGATAAGAGTTTTACTAGAAAGTCAACATTGCTCATTCATATGAAGAAACATTACGAGAGTGGAGAGGGCAGTTCTTCTGCTACTGGTCAGGGGGACGATGAATTCTCGTGTGATTTGTGCGGCGCGCAGTATGACAATGATCAGGCGCTGAGGGCACATCGGGCGAGGCATCACGGAGAAGAGGAAGAATCAGCGGAAGAGAGTGATGACGGTAATGTTCCTGCAGCACCCCCCGGTGAATTCACGTGTGCACAATGCGGCGATGGCGTCGCTACCCCCCGAGACCTCATCGCCCACCGCACGATGCATGCTACTCCCACCAAATTCTTCTGTAACATATGCAAAGTGTACTTCGCTCGGGCACTCGATCTCTCTTCGCACACTCGGGCGCGACACGCAGACAACGAAAAAGTATTCTTTCCGTGTGCCATGTGCGACAGATTTTACATGAACAAGAAGAGCTTACAGCGACATATTGAGATGGCTCACTGA
Protein Sequence: MNVNYDRVCRLCLSSRGELLPIFPTTSSDDSEPPVLASKIKDCVSIQINENDDLPTNVCRKCMDNVNNWHVFKNVCERTQNKLQSLKDGSQLEEVKIKSEPLSDEAYDDGVVIDGSYPVIENAGLSNKVQPEGPPILASLGLTPRSDKGAESENNEEEEEEMNEPAQSYPKVPHMPEVSITVMRPTGETLHARQGIHQLASKDCLVCGRSYRYSHNARRHELTSHSFDRYTNKITPKKTLTHLQPKLRPNPFNPKARMMPNPISHKMQFMNKNIPAKIMPINKVVTPQRPIPIKTSKASQNNLPYPLRIKALKDLQIKKKEPQILKTLLTSKPEVLVSEPEILNSGPESPETLISEPEIASFQVEAILTEPDAEAIIPDVDGYDHQQGDEEGDEEMHNNQNQHYDTVDMDSDNEIEIARQEGEQEGEQEGDDNADGDENVDQCEDDNNMEGAQSDNEKDVNDDTVESQEHMEEDDSLDIKPDGDMKDDDGQEEREHEDGEHDEEGEMNHNDVEEEEDDDLPMTLAPVVEINEGLQTNSFNSEVNEDDEELDETADPNDTIDDDDQVKELDPDKTYVTKTQRDFIQKYRDIIQQINTKRCLCCDREHPRRKAVIQHLQKNGHKVPKHTCYNCVITFGHIGALLSHMRSNSCTNLWKIIYNENGITDDLVLEDEPKEVKVQYKDIFNARSYACKLCPAKFQLKQFIMKHVLDTHEDGQSRVPLCCVHCRSRFKDKSLLKKHIRKGECTVYIACDLCAERFGNMQDFNDHALAVHAGSFDQSDNQSKCVDGRPTDCPLCGKKNSNYPNLVKHLKIIHSEEKPHYCQHCDSKFEQATDLNKHIYMEHSDRTLGMASSEPDMSIVKEEAEEYHYSCTECNAIFETVDAWTDHQVAEHNQVAHHCDQCEKKFLRPSELAEHKNTHLRVKFYPCSVCPNSYSTPQKLSEHVQQAHAGIGAVAATESEFFCDICIRSFKSRQAYSNHMRIHAKIPTTNRKPGVIKGGFAPQIIGKPIKQYPVVQPGFVSFKPNYNIPNAPYSCDICGKGFMHKKNIWKHKKVLHADILVDRHDSEENTMQASTEEEEFNPDENGAVLSTPQFNSFNFSNFPNNAQQASPATPYSCELCFKRFPLRTSLWKHKRAKHGFVNPSTSGSNDTSTASASGDTSSRSSCTICRITFADKKSYYRHRKTVHKSTVQMCKICGKPLSSTLELYEHLKAAHARELLGYNANQGSSKSQEMKQEIEPDYENDQESADPSVDYQARYPCDTCGKQFVGLLALQNHQCVNQIPAQPQTFDCEICHKSYTSISALKSHRGWHLRSPDGKAAANNSGLWMPQHKVTSKISKHEVVDPTQLAKVTHTPAPPPVSASAAKRRLPPEVEVTVVNPNKKLRSDDSVDMDMQNSGSMEDRYCTICDKEFTKRAAYQRHMDEVHQPNSVFCPVCDKSFTRKSTLLIHMKKHYESGEGSSSATGQGDDEFSCDLCGAQYDNDQALRAHRARHHGEEEESAEESDDGNVPAAPPGEFTCAQCGDGVATPRDLIAHRTMHATPTKFFCNICKVYFARALDLSSHTRARHADNEKVFFPCAMCDRFYMNKKSLQRHIEMAH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00852035;
90% Identity: iTF_00852035;
80% Identity: -