Basic Information

Gene Symbol
-
Assembly
GCA_002150865.1
Location
KZ116998.1:49315-62659[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 4.4e-05 0.0031 17.9 7.9 1 23 193 215 193 215 0.98
2 13 1.6e-06 0.00012 22.5 0.9 3 23 229 249 228 249 0.97
3 13 4.2e-05 0.003 18.0 2.1 2 23 258 279 258 279 0.98
4 13 1.8e-05 0.0012 19.2 1.5 3 23 287 307 285 307 0.95
5 13 1.3e-05 0.00094 19.6 1.4 1 23 313 335 313 335 0.98
6 13 1.3e-05 0.00092 19.6 8.6 2 23 342 363 341 363 0.97
7 13 1.8e-05 0.0013 19.2 0.8 1 23 369 391 369 391 0.98
8 13 1.3e-06 9.3e-05 22.8 1.1 1 23 397 419 397 419 0.99
9 13 0.00021 0.015 15.8 1.2 1 23 425 447 425 447 0.98
10 13 0.0021 0.15 12.7 0.7 1 23 453 475 453 475 0.96
11 13 1.6e-05 0.0011 19.3 0.5 1 23 481 503 481 503 0.98
12 13 4.5e-05 0.0032 17.9 2.8 1 23 509 531 509 531 0.98
13 13 8.8e-05 0.0062 17.0 3.1 1 23 602 624 602 624 0.99

Sequence Information

Coding Sequence
ATGGCTGCTCTGAATAAACCTTTGCAGTTTGACAAAATATGTCGCGCTTGTTTAGAGATAAAAAAGGACATGCGACCTCTATTTGAACAACTTACAGCAACGATGTTGATGGGCATATCGAAAGTGCAGGTGGCTGTAGGAGACGGCCTGCCCCCACAGCTGTGCCTCCAGTGCGTGCACCAGATCTCCCGGTGCCACGCCTTCAAGGACCTCGTCGAGAGGAATGACGTCACGCTCCGGGAACATGCCGCGCGCATGGCTGAGGAGGCCTTTAAGAGGGAGAGGGAGGAGAAGGACAAGTTACTGAGCCTAAACTGCGCGGAGCCGTCATACATGCAATACATGGAGGTGCCGCTGACCAACCCGGCTCAGATACTGGACGGCTTCTTCACGGCCACGCCGGACCCGCTGACTGCCGAAAACACCGAAAACACGGAGTCCAAACAAGAATATGAGGTTGAAAAGCTACAACCAGACATCGCTCAGCAGAAAGACAAAGAAGGTCTGAACTCTGACGAGGAGAACTACTTGCAACTGGTTTTATTCCAAGCGACGTCCACAGTGTCGCCCGGGCGTCATGTATGCAATCTCTGCCACAAGGAGTTCAAGCATTCGCGCTGGCTGAAGCAGCACATGCGCTCGCACACCAACTGGATCAAAGCTAATTGCAAGAAACCGCCCATGTGCTCTATCTGTGATAGAACTTTTAAGGGTCAGGGTATGCTAAAAATGCACATGCGTACCCACGAGGCGCGGCCTGCCAAGCAGCCGACATGCTCCGTCTGCCAGCGCACGTTCCCCACCAAGACGCTGCTGTACCGGCACCGGCAGACGCACTTCGAGCAGAAGACGCACCTGTGCACGGTGTGCGACAAGCGCTTCTACAGCGCGTATGCTCTGCGCTCGCACATGGCGAGGCACCGCGGCGAGCGGCCCTACGTCTGCTCCACTTGCACTAAGAGCTTCTATAACCCCACAGACCTTAAGGTTCATTTTCGCCTGCACACTGGTGAGAAGCCGCTAAAATGTACGGAATGCAACAAGACGTTCCGCCGTCACTCGACGCTGTGCCAGCACATGAAGAAGCATCGCGGCATTCGGAACCACGTGTGCACCGTGTGTAACAAGGGCTTCTATGAAGTGTCCAAGCTTAATGCGCACATGCGAGTGCATACTGGTGAGCGTCCATACGAGTGCCAGTACTGCGAGCGCCGCTTCGCGCAGCAGTCGGCGCTGATCTACCACCGCCGCACGCACACGGGCGAGAAGCCCTACAGCTGCAAGATATGCTTCGCGCGCTTCACCACCTCCTCCGCCAGGAACAACCATATGGTCACACATACTGGGAACAAGAGGTTCGCGTGCCCAGTATGCCTGAAGGGCTGCACGTCGCGCACGGAGCTGCGCGTGCACGCCAGCAAGCACACCGGCGAGAAGCTGTTCGAGTGCGGCGTCTGCCAGCAGCGCTTCAGCTCCGCCTCCTACCTCGCCGTGCACCGCCGCTACCACTCCGGCGAGAAGAAGTACCACTGCCAGGTCTGCGGGAAGGGTTACGTAGAATCGAACTCCTACAAGAAACACATGAAGACTCACGGCGTAAGCAAGTCGGAGACGGAGTCGTCCGCGTCGGAGGCGAGCGCCGACAAGACCGACGCGACCGTCACCGAGCATACCACCACCAGCACTGATGATATGGACGTGCAGAACCAAGCTCAAGGTCAAATCCAAATCCAAGTTCAAGAGCAACAAGTCCTTCAAGTTCAAGGTCAAGTGGAGCGTCCTCCGCAGCAGAAGGTCACTCGCTACAAATGCGGCTTCTGCGTGAAGACATACATGAATTTGCACAACTTAAAGAAACATATGCTGGTGCACACACAAGCCAATCAGGATAACACCCGAAACTCGGAGCCAATAATATTCCTCACACAACAGCAAACgcagcaacaacagcagcaacaacaacaacaacaacaacaagtGCAACAACAACAGGTGCAAGTGCAACAACAGCAGGTGCAACACCAACAGTtgcagcaacaacaacaacaacaccAACAAGTCCAACAAGTACAAGTGCAACAGCAACAAGTGCAACAACAAGTGCAACAGCAGGTGCAACACCATCAACAACAGCAGTTGCAGCAACAGGCTGTGTTGCAGGTCGGCAACGTGCAACAGCTAGCGGTACCGATACACGCGCAGCATGTTCAACAAGGCATCACTGTGTCTGGTGTTCAGAGCCAGCACCCGTACCCGGTGATATCTTCAGTGCAGTCGCTGCAGCTGCAGCAAACACAACAGGTTAACACGCAACAGCCGCAGCAGCTTCAAGTACAAACCATACAGATACACCCGCAGCATCAACCTATACAAATACACGCTGTGGGCGTGCAACAAGTGCAGCAGCAACAGTTGCACGTGGCCACCTCCTCGTGTCAGACCATGCTGCCCAATATATTACAGCTGCAGCCGGGCACGGTGGCGGTGTCGGGGCTGGGGCAGCAGGAGCTGGGCGGCGTGACGCACCGCATCATCCTGCAGCCGCAGCCCGCGCCGCCGCACCCTGCGGTCTACACCATACACCACTGA
Protein Sequence
MAALNKPLQFDKICRACLEIKKDMRPLFEQLTATMLMGISKVQVAVGDGLPPQLCLQCVHQISRCHAFKDLVERNDVTLREHAARMAEEAFKREREEKDKLLSLNCAEPSYMQYMEVPLTNPAQILDGFFTATPDPLTAENTENTESKQEYEVEKLQPDIAQQKDKEGLNSDEENYLQLVLFQATSTVSPGRHVCNLCHKEFKHSRWLKQHMRSHTNWIKANCKKPPMCSICDRTFKGQGMLKMHMRTHEARPAKQPTCSVCQRTFPTKTLLYRHRQTHFEQKTHLCTVCDKRFYSAYALRSHMARHRGERPYVCSTCTKSFYNPTDLKVHFRLHTGEKPLKCTECNKTFRRHSTLCQHMKKHRGIRNHVCTVCNKGFYEVSKLNAHMRVHTGERPYECQYCERRFAQQSALIYHRRTHTGEKPYSCKICFARFTTSSARNNHMVTHTGNKRFACPVCLKGCTSRTELRVHASKHTGEKLFECGVCQQRFSSASYLAVHRRYHSGEKKYHCQVCGKGYVESNSYKKHMKTHGVSKSETESSASEASADKTDATVTEHTTTSTDDMDVQNQAQGQIQIQVQEQQVLQVQGQVERPPQQKVTRYKCGFCVKTYMNLHNLKKHMLVHTQANQDNTRNSEPIIFLTQQQTQQQQQQQQQQQQQVQQQQVQVQQQQVQHQQLQQQQQQHQQVQQVQVQQQQVQQQVQQQVQHHQQQQLQQQAVLQVGNVQQLAVPIHAQHVQQGITVSGVQSQHPYPVISSVQSLQLQQTQQVNTQQPQQLQVQTIQIHPQHQPIQIHAVGVQQVQQQQLHVATSSCQTMLPNILQLQPGTVAVSGLGQQELGGVTHRIILQPQPAPPHPAVYTIHH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01094252;
90% Identity
iTF_00783731;
80% Identity
-