Basic Information

Insect: Heliconius sara
Gene Symbol: Baz2b
Assembly: GCA_917862395.2
Location: OU860786.1:2435462-2472948[+]

Transcription Factor Domain

TF Family: MBD
Domain: MBD domain
PFAM: PF01429
TF Group: Unclassified Structure
Description: The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 6.5e-10 1.4e-06 28.2 0.0 3 75 576 651 574 653 0.86

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	6.5e-10	1.4e-06	28.2	0.0	3	75	576	651	574	653	0.86

Sequence Information

Coding Sequence: ATGGACAAGGAGAACGGAGAGGGCGATGCGGCAGCCAAGCCGCCGCCCGACGGCCTGCTCGACCCGTCTGGACTTTTTGGAGCCTACTGGCCCAGAGATGCCACAGCCGGCGGTGCAGCAGCTCAAGCACAGGCCCAAGCGCAGGCGCAAGCGGCCCTCTTCGGATTCGGCTCCAGATACCCCCCACCGACGACGCTGGGGGTCGCCGCAAACCAGGCAGCTTCTCTTGGACTGCATCCTGCTGCCAGTGCAGCATGGTGGTCCATGGCGTCCCATCTCGCGGCACAAGACTACTTAGCCAGGCTACAAGCGTCCGGGCTGAACTTCCCACCCTTGGGTGACCCCTACGCCGCATTGTCGGCCTTATCAGGGAGTGGCATGAAACAGCCGGTGAAGCCTGTCAAACAGAGTAATAGGAGTGAAAGCAGATCAGGTAGAAGCAGTACGTCGTCGAGTGTGTCCACGAAGGAAAAAAGCCCGTCCACCAACACGTCTAGCTCACAGCACAATATTGCTGATTGGGgtTCGCAATATGGTTTTCCAAAGACTTCATCACCTTCGACGATGCCGTCTCAGTCCATGTCGTCGCTCGCTTCACTCAACAACTTGGCGCAGCAGCCGTTGCATTCCAAATCCAGTAAAGGACAGCCGCCAAgAAAAAGTAGCTCGAGTAGTAAAGAAAAGGAAAGAGAACTCATGCTTGCGCACGCGCATTCAGCCTACCACGCCGCTCTACAAGCTCACAAAGGAAAGAACATGTCTCCGCTATATCCATTCGCAGTTGGTTCAGAGAAGGATAGAAGAAGTGGTATCGACACGCTCACCGGCTTACCACATACAATACTTAGTGCTGCATTGGAAGGCGGTGATCCTTCATCAGTATTGGGTGGAGTGAGATTGCCTCCAGACACtgagattataaaatatacgtctTCTTTGGCTGGACCAAAGTCGGCCCCGGGCAGCACGACCCGCGGCCGCAAGAAGACCATATCGCTGGACCCGCCGCACGTGTCCGTGCACCCCGCCGGCGAGCGCGCGCCCGCGCCCAGCAAGCGCCAGAAGGTGGACGAGTATGGTAATTCGAGATCGTCAGTGGAAGTCATACGTTTGCCGAACAAACCCGATAGGTCTGCTAACTCCGTATCGGGCACACCTCCGCCCAATTTGTCTGATTACGCAGgtatatctCGAGAACTATTACAAACAATAGCAAGTCAAAGTGGAGTCAGTTTGGCGGCCTTAGAGAGGCAACTCGCTGGATCCGGAGCAGCTAGTACTGCCATTGCCCAAGCATCAGATGCGTTGTCTCGTCTGACGTCACTGAGCAGTTCTCTTAGCGTTTCCAATGATagaatatcACGTCGCAAGCCCGGCGCTAAACCGCGTCGCGTAGCTCCAGAGCTGAATTCCCAAGTCGCGGATTCACCACGACCCAAGTCCAGCGGAAGCGAGGATAGtgaatCGGTATCCCCTTGGCCGTCCCGTGAAGGTCGCCCCCGTAACCTCGGTCGAGGAGTCAGCAAGCCCAAGAAGAACACAGTAGCGTCGTTGCTAGCCCAGAGCAGAGCCCTAGGCCTCCGCCCCGCCCTGGCACACCATTTATTAGCTGAAAGCGATAttGACAAATTACGAGCTCTCCTGGGTGAAACAGCGAGCACCGATTCAGAATGTCCCTCAGACAGCAACCCGTCGGACTCAGACGCGAGCGACGGTGGTCGCAGGCACGATTCCCAGTTGAGGCTGCCTTTGGCTTTGGGCTGGAAGCGCGTGACGCTGATCAGGGGCCTGTCGCGCAGCTGCAACATCAAGGGCGACGTGAGCTACACGCCGCCGGAGCCGCACGCCGCGCGGCACGTGCGCGGCGCGCGCGAGCTGCAGGCGTTTTTGGAATCTAATCCCAGTCCACCGCTATGTCGTGACAACTTCAGCTTCAGCGCCCGCACTCTCCTCGGTGAATACGTGCAGCCGTCCCTTGATAATGCTGAGCCTTTAGTACTGAACGAAACTGAAATAAGTAAACGGCTGGAGGAGGCGCGCTCGCTGGCGGCGCTGAGCGGGCGCCCCACGCCGCCGCCGCTGGAGCGCCGCATGGAGCTGGCGCGGCGCCAGCAGGCCGCGCGCGACGCGCGCCGCGACTGCGCGCACCGCGGCCGCGACCAGGCTCGTCTAGTCAGAGACCTGGAGAGGTCGGAGAAAGCCGAGTTAGTTAAACGCGAGAAAGAGGCGCGAAGCCAGCAATTGTTGGAGCATATCAACAAGGGCAGATCGCAGCTAAGCATAGAGCCGTTGCCGAATAAACCAGACGAGTGGAAAGTTCCAGATATCGTAATGGGCCCAGCCATTAAGAGTAACAGGGACAGAACTATGCCGCAAATCAGTCTGTCTCTTATACCAGTCAGTGGGCTGAAAGAAAACACGCCTATTAAAACTGTCAGCGTAGATCAGTTTAAAGGCGAAGAAGAGTACAATGCTTTGGACAAAATGAAGGATTTTGCCGAAAAAGCCTCCTTTGATCTCCCAAAACGGCCTAGCgacaaatattttgatttctcgTTGACTAAGACGCCGGATAAAAGAAAAATGCCGGATCAAGAGAATAATTTGGAAAAGTTAATAGAGTCGTATTCCCGTATATCGGAGTTCATCAATGGTTGTGATTGGTCGAAACTGCGAACTGGCAAACAAACAGACGATCCGAAAAGCATAGAGCAGAAATATTTAGACGCAAAAAACGAATTTATGTcccaaaatctaatgttaatgCCTAAAGACAATCAAAAATCAGTTTTAAAAGAAGTTATAGATCTAAGTGGTGATGATGATATTCTAACTGATATAATATCTAAGAAAGTGAGCCGAGGCACTTTCAATGTGGGAAAGGACGGAGCCTTATCAATATCGGTACAGCCTTTGAAGGACGTTTACAGTCCGGCTAAGAAGAGAAAGCAAGAGGAGTTGGAAAAGCAGAAAATGGAGGAACAAGCTAAACGGCAACAGgaAAGAGAATTGAAGAGACAACAGGCTATGCTTTTAAAAGAACAGcaaaaatatataacggaGGAACGTGAGAGACGTCGTCAACACACCACCTTCATACGACAACTGGACTCGCGTAGACGATGGGAGGACAGGGAGAGGAGAAAACACCAGAACCTTCTGGATCGATTGCTCGTCAAGGAGAAGAAGCTGCAGCAGAGACGAAAGGAGATGGAGTTGCTTTCTGAGTTGAGACGACCGCAGGAAGACTCATCTCTCTCAGATCAGAAGCCTCTACCAACATTGGATCGTGTCCCCGGACTAAAGATACCGGGGCAGGCTATGGCCGACCTACTGCAAGTTTACGAGTTCTTGCACAACTTCGGTCAGGCACTTGGATTTGAAGTAGATTCCCTGCCATCGTTGAATACTCTACAAATGGGTCTAATACCCAATTGTAATCAAGAGGCTGAAGATGAACTGCTCAATGTGCTGTCCAGATTGTTATCTATTGCTATAGAGGAACCAGGCATCCCTCATCCCGGCCGCCACACAACGCTCCTCGGACACGCGCTGCGCCTCGCAGAGCTAAGCGCCGATACTATAAGTGAAGTCCTTCGCATTTATTTGTACGCGAACGCTACCGCTGAGGTTAAGGCATTGACGGGTCTAACAGTAGAGAGAGAACGAGACAGGCGCGTGGCCGACCACCACCAGAGCGACGCGGAGATGCAGCAGACGTGCGCCAGCACCAAGAACCACCTGTACTACGAGCACCTGCACTCCAACGCCACGTACAAGCTGTCCGAGCTGCTGCGCGACAAGCCGTTCGCGGCGCTGGCGCCCAGCAGCAAGGCGCGCATGCTGGCGCGCACGTGCGACGAGCTGCTGCAGAGCCGCGCCGTGCTGCGCCAGCTCGACGCCTCGCTCGACCACCTGGCGCAGCTGCGGCGCGACCGCTACCTGCTGGACGCGCGCATTCGGAAAGTCCGCGCGCTTCAACAACGGAAAGCTCGTGCCGAAGCAACGGAACGACAACAGGCGCTCGCGTTGGAACGAATGCAACGATTAGTGGATATACCTACTTACGATACTGacACCTCAGAAAAATCCGAAACACCCAAAAAGCAAGAGAAAGAGCTGTCACCAGACAAACCACAAACGCCATCTCCATTTAAAGACACGCCAGAAGAGAGTGATAAAGAACTATCGCCTTTAAAAGACTTATCCAACGTGAAAAaagagatattaaataataataaagaagaaaCACCCGACGTGAAGATAGATAAAGACAGCGTTATGGGGGATGAGGGGCTGAGTGATTTGGAGAGTGAGGGCACTCAACCGGAGGAGGATGAAGATAAAAACCTAACATCAGAAGAGTTGTCCCGTAAATTAGAGAAGCTTATCCGTCAATCGGAACAACAGTTAATAGCTCTCGCAGCCGGTTCACACGCATTGAGAGCCACTTGCTATGGACAGGATagataCTGGCGTCGCTACTGGTCGCTCGGCAAAGCGGGAGGTGTGTACGTAGAAGCAATGGAGTCAGCTCAGCcagaaatattacaatatcaCGCCAAATTAGAACAGGATGCTCTTAATCCACCGCCTAAAGTTAAGAAAGtaAAAGAAAAATTCGAACCTAAACTATTCGACGATGATGAGCCACAACTACAAATAGACGAAGAGGCTGAAGCATTAGAACTGAAAAGTATTAAAAGTGAACTCAatttaagtgacagaactcaaattataaaatacgagCCCAATGTTACGCACGGAGCGTGTAAAGTTGAAGGTTCAATAAAAATGGAAGAGAAATACATTCAACAGAAACAAAGTAACGAAGAGGAAGATATGCTGGACATAGAAGACTCCATTCCTACTGCGTTTTTAGTTCAAAAACCAACGCACAAACCACTATACGCCACCCAAGCAGAGCCAATGGACAAGCCTCAAGAAATAGTCAAAGTTGAAAATGTCGCTAAAGAAGAAGAACcagaagaaaataaagataactTAGTAAACAATTTAGAAGAATTACGCAAAATGGCGGAAGCCGTTTCCTCACAACTTGATGCCGCCAAAAAGGCGGAAACTGAAAAAGCTGAAAAAGAAGCAAAAATAGAACCAGAAGTCAAAACAGAAGTAATGGAAGCGGACACCGCTCACGCGCTCCTTTATAACAAAATGATGGAAGGCAAATGGTTTTCAATACTGAGACACgaaaattcatttttaactaGTATAAATGACGATAAAACCAACGATGTGCCGCCATTTTGTGATAACGAGCACACTTGTAATGAAGTTGTCAACTGTCAAGGGCATAAGTGGGATGTGTCTAATAATTTGCATTTATTGAATGATCCCAGCTTATTCACGTTAAATTCTATGGTGACTAGTGTCCAAGTGCcgtcatataatatatacacgGACTCCAGCTTGACCATGTCCGGCTTGGACCAGGATATGATGGATGCGAGTATGAACAAAGATGGCGCCCGTGAACCGGAAGTGGAGGAGAGTAAGGAGCAGGAAAACGACCTAGAAAAGGAACTTCAAGCGGATACCCTTAAGGAGCAAACGAACAAAGCGAAAGCAACAGGTCTTTCCAGCCTCGGCGTGCTGAACTTCAACGCGCTCTCCACATACGTGACGTGTGACAGCCCCCCGCCCATACACATGTCCGTGGAGGAGATGCAGCAGCTGGAGGTGGTGAAGGTCCAGGGTCTGCCCAAGAGGGTGGAGGGGAAATATGTGGAACGGGATAACAGACACGGGTGGTGGCGTATAACGGAAGCGGAGCAGCTGAAGGTGCTGCTGGACGCGCTGCACTCGCGCGGCGTGCGCGAGCGGGAGCTGCACGCCGCCTTCACGCAGCACATGCCCACCTTGAACAATAAGCTGCACGTGGACAGGGGCGACGCGAGCAGCCGCCTAGACGCGccggcgccgcgcgccgccagcCCGCCGCCCGCCGACGACCCCAACACGTTCTGCGCCCTCACGGCGCGGCGCGTGGACATGCATCTGTTGTCTATGGTGGAGGCGCTGGAGGAGCGCGTGGCGGCCGCGTCCATGCAGGTGAAGGGCTGGCGCGCGGCGCGCCTGGCGCTCCCGGCCGCGGCCACGGGCGCCGAGATCGTGGCGCGCGCGCGCCACAAGCTGGCCTCGCTCGAGGCGCACATCGAGCGCCGCTACCTCAAGCCGCCGCTCGTGCACAGGCCATCTTGCAGCACGACCGAGGCGACGCTGGGCGCCGTCCTGCAAGCGGAACACGGAACATCCGCTTCGCCCAACGATCAAGCCACTGAAACAAAGAGCGCGGGCGTGGCGCGCGGGCTGGCGCAGTGGCGCGAGGCGGTGGCGCGCTGCAACACGTCGGCGCAGCTGGCCATGCTGCTGCGCGCGCTCGAGCACGCCGTCGCGTGGGACAAGAGCATTATGAAGGCGaaTTGTCAGTTCTGTTTGTGTGGAGATAATGAAGACCAGCTGTTACTGTGTGACGGATGTGATAAAGGCTATCACACTTACTGCTTCAAACCGAGAATGGAGAAGATTCCAGAAGGAGATTGGTACTGCTGGGAGTGCGTGAACAaggcgcgcggcggcgggcgcgagCGCGTGTGCATCGTGTGCGGCGGCGCCGCAAGGGGGCGCGCGCTGCCCTGCGCGCTGTGCGTGCGCGCCTTCCACCTCGACTGCCACTACCCGCCGCTGCTCAAGATGCCACGGGGCAAATGGTACTGTTCCCAATGCATATCGCGCGCGCCGCCCAAGAAACCGAGGAAAACAAAACGCGACACGAAACACAAGGACAAGGACAACAGTAACACCGACCTAGACTCCAGCATGGTGCCCAGTCCTGCCTCCCACGCCTCAACATCGACAACAGCAGAGGAGTGTCCGATCACTACGCAAACAGACACTACGGAAAAGTTAGACGAGTCACTAATAGAGACTCCTACACCCACGCCCACGCCCACTCTCACACCCACTGCGACTCCCGTTTCTATGAATATGTCTGTGAATAGTCAATTAAGTAATAGTGGACTGAGTGGCGACTCTGAGAACGGATTGAATCATCATACAGTACCAGAAATACAAGAAGACGGTCCTCCGCCGGAAAAGCGGCGAGCGTTACAGTTCCCGAGCAACGGCGCCCTACACGATGATGGCGACGCGGTAGACGGACACGtagATGAACTTGAATCGGAAAATTTGCCGCTTTTGTCTCGAGCCAAGAAAGACAAAAGCTCAGCCAAGAAACTTATTAAGGAATTACAGTTTTGCAAGAACCTTCTCTGTGAAATGGAATGCCACGAGCACGCGTGGCCGTTCCTCGTGCCTGTCAACACCAAGCAGTTCCCACAGTACAAGAAAGTTATTAAATGTCCCATGGATCTGTCCACTATCAAGAGGAAATTACATGACTCTATCTACAAGTGCAAGGAAGAATTCGCATCTGACGTTCGCCTGATATTCAGCAACTGTGAACGCTGGGCCAATGTTTGA
Protein Sequence: MDKENGEGDAAAKPPPDGLLDPSGLFGAYWPRDATAGGAAAQAQAQAQAQAALFGFGSRYPPPTTLGVAANQAASLGLHPAASAAWWSMASHLAAQDYLARLQASGLNFPPLGDPYAALSALSGSGMKQPVKPVKQSNRSESRSGRSSTSSSVSTKEKSPSTNTSSSQHNIADWGSQYGFPKTSSPSTMPSQSMSSLASLNNLAQQPLHSKSSKGQPPRKSSSSSKEKERELMLAHAHSAYHAALQAHKGKNMSPLYPFAVGSEKDRRSGIDTLTGLPHTILSAALEGGDPSSVLGGVRLPPDTEIIKYTSSLAGPKSAPGSTTRGRKKTISLDPPHVSVHPAGERAPAPSKRQKVDEYGNSRSSVEVIRLPNKPDRSANSVSGTPPPNLSDYAGISRELLQTIASQSGVSLAALERQLAGSGAASTAIAQASDALSRLTSLSSSLSVSNDRISRRKPGAKPRRVAPELNSQVADSPRPKSSGSEDSESVSPWPSREGRPRNLGRGVSKPKKNTVASLLAQSRALGLRPALAHHLLAESDIDKLRALLGETASTDSECPSDSNPSDSDASDGGRRHDSQLRLPLALGWKRVTLIRGLSRSCNIKGDVSYTPPEPHAARHVRGARELQAFLESNPSPPLCRDNFSFSARTLLGEYVQPSLDNAEPLVLNETEISKRLEEARSLAALSGRPTPPPLERRMELARRQQAARDARRDCAHRGRDQARLVRDLERSEKAELVKREKEARSQQLLEHINKGRSQLSIEPLPNKPDEWKVPDIVMGPAIKSNRDRTMPQISLSLIPVSGLKENTPIKTVSVDQFKGEEEYNALDKMKDFAEKASFDLPKRPSDKYFDFSLTKTPDKRKMPDQENNLEKLIESYSRISEFINGCDWSKLRTGKQTDDPKSIEQKYLDAKNEFMSQNLMLMPKDNQKSVLKEVIDLSGDDDILTDIISKKVSRGTFNVGKDGALSISVQPLKDVYSPAKKRKQEELEKQKMEEQAKRQQERELKRQQAMLLKEQQKYITEERERRRQHTTFIRQLDSRRRWEDRERRKHQNLLDRLLVKEKKLQQRRKEMELLSELRRPQEDSSLSDQKPLPTLDRVPGLKIPGQAMADLLQVYEFLHNFGQALGFEVDSLPSLNTLQMGLIPNCNQEAEDELLNVLSRLLSIAIEEPGIPHPGRHTTLLGHALRLAELSADTISEVLRIYLYANATAEVKALTGLTVERERDRRVADHHQSDAEMQQTCASTKNHLYYEHLHSNATYKLSELLRDKPFAALAPSSKARMLARTCDELLQSRAVLRQLDASLDHLAQLRRDRYLLDARIRKVRALQQRKARAEATERQQALALERMQRLVDIPTYDTDTSEKSETPKKQEKELSPDKPQTPSPFKDTPEESDKELSPLKDLSNVKKEILNNNKEETPDVKIDKDSVMGDEGLSDLESEGTQPEEDEDKNLTSEELSRKLEKLIRQSEQQLIALAAGSHALRATCYGQDRYWRRYWSLGKAGGVYVEAMESAQPEILQYHAKLEQDALNPPPKVKKVKEKFEPKLFDDDEPQLQIDEEAEALELKSIKSELNLSDRTQIIKYEPNVTHGACKVEGSIKMEEKYIQQKQSNEEEDMLDIEDSIPTAFLVQKPTHKPLYATQAEPMDKPQEIVKVENVAKEEEPEENKDNLVNNLEELRKMAEAVSSQLDAAKKAETEKAEKEAKIEPEVKTEVMEADTAHALLYNKMMEGKWFSILRHENSFLTSINDDKTNDVPPFCDNEHTCNEVVNCQGHKWDVSNNLHLLNDPSLFTLNSMVTSVQVPSYNIYTDSSLTMSGLDQDMMDASMNKDGAREPEVEESKEQENDLEKELQADTLKEQTNKAKATGLSSLGVLNFNALSTYVTCDSPPPIHMSVEEMQQLEVVKVQGLPKRVEGKYVERDNRHGWWRITEAEQLKVLLDALHSRGVRERELHAAFTQHMPTLNNKLHVDRGDASSRLDAPAPRAASPPPADDPNTFCALTARRVDMHLLSMVEALEERVAAASMQVKGWRAARLALPAAATGAEIVARARHKLASLEAHIERRYLKPPLVHRPSCSTTEATLGAVLQAEHGTSASPNDQATETKSAGVARGLAQWREAVARCNTSAQLAMLLRALEHAVAWDKSIMKANCQFCLCGDNEDQLLLCDGCDKGYHTYCFKPRMEKIPEGDWYCWECVNKARGGGRERVCIVCGGAARGRALPCALCVRAFHLDCHYPPLLKMPRGKWYCSQCISRAPPKKPRKTKRDTKHKDKDNSNTDLDSSMVPSPASHASTSTTAEECPITTQTDTTEKLDESLIETPTPTPTPTLTPTATPVSMNMSVNSQLSNSGLSGDSENGLNHHTVPEIQEDGPPPEKRRALQFPSNGALHDDGDAVDGHVDELESENLPLLSRAKKDKSSAKKLIKELQFCKNLLCEMECHEHAWPFLVPVNTKQFPQYKKVIKCPMDLSTIKRKLHDSIYKCKEEFASDVRLIFSNCERWANV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00621256;
90% Identity: iTF_00780272;
80% Identity: -