Hsar012171.1
Basic Information
- Insect
- Heliconius sara
- Gene Symbol
- Ssrp
- Assembly
- GCA_917862395.2
- Location
- OU860791.1:16621236-16647043[-]
Transcription Factor Domain
- TF Family
- HMG
- Domain
- HMG_box domain
- PFAM
- PF00505
- TF Group
- Other Alpha-Helix Group
- Description
- High mobility group (HMG) box domains are involved in binding DNA, and may be involved in protein-protein interactions as well. The structure of the HMG-box domain consists of three helices in an irregular array. HMG-box domains are found in one or more copies in HMG-box proteins, which form a large, diverse family involved in the regulation of DNA-dependent processes such as transcription, replication, and strand repair, all of which require the bending and unwinding of chromatin. Many of these proteins are regulators of gene expression. HMG-box proteins are found in a variety of eukaryotic organisms, and can be broadly divided into two groups, based on sequence-dependent and sequence-independent DNA recognition; the former usually contain one HMG-box motif, while the latter can contain multiple HMG-box motifs. HMG-box domains can be found in single or multiple copies in the following protein classes: HMG1 and HMG2 non-histone components of chromatin; SRY (sex determining region Y protein) involved in differential gonadogenesis; the SOX family of transcription factors [1]; sequence-specific LEF1 (lymphoid enhancer binding factor 1) and TCF-1 (T-cell factor 1) involved in regulation of organogenesis and thymocyte differentiation [2]; structure-specific recognition protein SSRP involved in transcription and replication; MTF1 mitochondrial transcription factor; nucleolar transcription factors UBF 1/2 (upstream binding factor) involved in transcription by RNA polymerase I; Abf2 yeast ARS-binding factor [3]; yeast transcription factors lxr1, Rox1, Nhp6b and Spp41; mating type proteins (MAT) involved in the sexual reproduction of fungi [4]; and the YABBY plant-specific transcription factors.
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 8 6.2e-15 4.7e-12 46.6 0.0 1 41 308 348 308 368 0.91 2 8 6.2e-15 4.7e-12 46.6 0.0 1 41 475 515 475 535 0.91 3 8 2.1e-13 1.6e-10 41.7 0.0 1 41 642 682 642 702 0.91 4 8 2.1e-13 1.6e-10 41.7 0.0 1 41 809 849 809 869 0.91 5 8 6.2e-15 4.7e-12 46.6 0.0 1 41 1117 1157 1117 1177 0.91 6 8 9.6e-15 7.3e-12 46.0 0.4 1 40 1284 1323 1284 1349 0.95 7 8 1.2e-20 9.2e-18 64.9 4.0 1 69 1354 1420 1354 1420 0.98 8 8 5.3 4e+03 -1.3 8.2 42 63 1489 1511 1483 1515 0.70
Sequence Information
- Coding Sequence
- atgGAAAGGCGATGGAAAGTCGATGATAGTTGGAAACTTGGACGAGAAAACTACGTACCCTTCCTACACAGTGATAGTAACAAATCACCAGTAATAGTTATGTATATACTTTCATTTAACCGTGGGAATACTACACTACGAGCAAGAGAGGAGTTAAGAGACAAATATGAAGGAAAGATTAGTAAGGAACTATCAGGACCCACATATGAAGTACTTGCCAAGATTATGAAAGTTGTCATCAATAGAAGAGTCACAGGTCCTGGAGGCTTCTTAGGcCACCACAAGACACCAGCTATCGCTTGCTCATATAAGGCAGCGGCTGGATACCTCTACCCATTAGAAAAGGGCTTCATATATGTACACAAGCCACCAGTACACATACGTTTTGAAGAAATAGCCTCTGTTAACTTTGCGAGAGTTGGCACTTCATCTACTAAgTCCTTTGATTTTGAGATAGAACTTAAATCTGGCAACGTGCACACCTTCAGCTGTATAGAAAAGGGAGAATACGACAAATTATTTGATTACATTACATCTAAGAAACTTCATGTAAAGAATACTGGCAAAAATGATAAAGCACTCTACGACGATGACTTCGGCGACTCCGACACTGAAAAGGAACCGGATGCATATCTCGCACGAGTCAAAGCTGAAGCTAAAGAACGGGATTCTGGTGACAGCGATGGCTCCGATGAAAGTACTGATGAAGACTTCAACCCAGATAAAGCTAAAGAGAGTGATGTTGCCGAGGAATATGATACTAACCCATCGTCATCGGAAGAGTCCGACGCTTCCAATGCATCTGGAGACAGTAAAAAGGAAAAGAAGAAAGAGAAGAAACCTAAAAAGACAATAACCATTTCGGAAGCACCAAGAAAACGGAAAGAAAAATCGAAGAAACGTGAAAAAGACGCAAACGCCCCGAAACGTCCAGCGACAGCATTCATGTTGTGGCTCAATGAAAGCCGTAAACGGATTATGGATGAAAACCCTGGTATCAAAGTAACTGATGTCGCTAAGAAGGTCGGAGAGCTGTGGCGGAGAGATGTGGCGTATTTGAGTGATAAGTCGGATAAAGCACTCTACGACGATGACTTCGGCGACTCCGACACTGAAAAGGAACCGGATGCATATCTCGCACGAGTCAAAGCTGAAGCTAAAGAACGGGATTCTGGTGACAGCGATGGCTCCGATGAAAGTACTGATGAAGACTTCAACCCAGATAAAGCTAAAGAGAGTGATGTTGCCGAGGAATATGATACTAACCCATCGTCATCGGAAGAGTCCGACGCTTCCAATGCATCTGGAGACAGTAAAAAGGAAAAGAAGAAAGAGAAGAAACCTAAAAAGACAATAACCATTTCGGAAGCACCAAGAAAACGGAAAGAAAAATCGAAGAAGCGTGAAAAAGACGCAAACGCGCCGAAACGTCCAGCGACAGCATTCATGTTGTGGCTCAATGAAAGCCGTAAACGGATTATGGATGAAAACCCTGGTATCAAAGTAACTGATGTCGCTAAGAAGGTCGGAGAGCTGTGGCGGAGAGATGTGGCGTATTTGAGTGATAAGTCGGATAAAGCACTCTACGACGATGACTTCGGCGACTCCGACACTGAAAAGGAACCGGATGCATATCTCGCACGAGTCATAGCTGAAGCTAAAGAACGGGATTCTAGTGACAGCGATGGCTCCGATGAAAGTACTGATGAAGACTTCAACTCAGATAAAGCTAAAGAGAGTGATGTTGCCGAGGAATATGATACTAACCCATCGTCATCGGAAGAGTCCGACGCTTCCAATGCATCTGGAGACAGTAAAAAGGAAAAGAAGAAAGAGAAGAAACCTAAAAAGACAATAACCATTTCGGAAGCACCAAGAAAACGGAAAGAAAAATCGAAGAAACGTGAAAAAGACGCAAACGCGCCGAAAAGTCCAGCGACAGCATTCATGTTGTGGCTCAATGAAAGCCGTAAACGGATTATGGATGAAAACCCTGGTATCAAAGTAACTGATGTCGCTAAGAAGGTCGGAGAGCTGTGGCGGAGAGATGTGGCGTATTTGAGTGATAAGTCGGATAAAGCACTCTACGACGATGACTTCGGCGACTCCGACACTGAAAAGGAACCGGATGCATATCTCGCACGAGTCATAGCTGAAGCTAAAGAACGGGATTCTAGTGACAGCGATGGCTCCGATGAAAGTACTGATGAAGACTTCAACTCAGATAAAGCTAAAGAGAGTGATGTTGCCGAGGAATATGATACTAACCCATCGTCATCGGAAGAGTCCGACGCTTCCAATGCATCTGGAGACAGTAAAAAGGAAAAGAAGAAAGAGAAGAAACCTAAAAAGACAATAACCATTTCGGAAGCACCAAGAAAACGGAAAGAAAAATCGAAGAAACGTGAAAAAGACGCAAACGCGCCGAAAAGTCCAGCGACAGCATTCATGTTGTGGCTCAATGAAAGCCGTAAACGGATTATGGATGAAAACCCTGGTATCAAAGTAACTGATGTCGCTAAGAAGGTCGGAGAGCTGTGGCGGAGAGATGTGGCGTATTTGAGTGATAAGTCGGATAAAGCACTCTACGACGATGACTTCGGCGACTCCGACACTGAAAAGGAACCGGATGCATATCTCGCACGAGTCATAGCTGAAGCTAAAGAACGGGATTCTAGTGACAGCGATGGCTCCGATGAAAGTACTGATGAAGACTTCAACTCAGATAAAGCTAAAGAGAGTGATGTTGCCGAGGAATATGATACTAACCCATCGTCATCGGAAGAGTCCGACGCTTCCAATGCATCTGGAGACAGTAAAAAGGAAAAGAAGAAAGAGAAGAAACCTAAAAAGACAATAACCATTTCGGAAGCACCAAGAAAACGGAAAGAAAAATCGAAGAAACGTGAAAAGACGCAAACGCGCCGAAAAGTCCAGCGACAGCATTCATGTTGTGGCTCAATGAAAGCCGTAAACGGATTATGGATGAAAACCCTGGATAAAGCACTCTACGACGATGACTTCGGCGACTCCGACACTGAAAAGGAACCGGATGCATATCTCGCACGAGTCATAGCTGAAGCTAAAGAACGGGATTCTAGTGACAGCGATGGCTCCGATGAAAGTACTGATGAAGACTTCAACTCAGATAAAGCTAAAGAGAGTGATGTTGCCGAGGAATATGATACTAACCCATCGTCATCGGAAGAGTCCGACGCTTCCAATGCATCTGGAGACAGTAAAAAGGAAAAGAAGAAAGAGAAGAAACCTAAAAAGACAATAACCATTTCGGAAGCACCAAGAAAACGGAAAGAAAAATCGAAGAAACGTGAAAAAGACGCAAACGCGCCGAAACGTCCAGCGACAGCATTCATGTTGTGGCTCAATGAAAGCCGTAAACGGATTATGGATGAAAACCCTGGTATCAAAGTAACTGATGTCGCTAAGAAGGTCGGAGAGCTGTGGCGGAGAGATGTGGCGTATTTGAGTGATAAGTCGGATAAAGCACTCTACGACGATGACTTCGGCGACTCCGACACTGAAAAGGAACCGGATGCATATCTCGCACGAGTCATAGCTGAAGCTAAAGAACGGGATTCTAGTGACAGCGATGGCTCCGATGAAAGTACTGATGAAGACTTCAACTCAGATAAAGCTAAAGAGAGTGATGTTGCCGAGGAATATGATACTAACCCATCGTCATCGGAAGAGTCCGACGCTTCCAATGCATCTGGAGACAGTAAAAAGGAAAAGAAGAAAGAGAAGAAACCTAAAAAGACAATAACCATTTCGGAAGCACCAAGAAAACGGAAAGAAAAATCGAAGAAACGTGAAAAAGACGCAAACGCGCCGAAACGTCCAGCGACAGCATTCATGTTGTGGCTCAATGAAAGCCGTAAACGGATTATGGATGAAAACCCTGGTATCAAAGTAACTGATGTCGCTAAGAAGGTCGGAGAGCTGTGGCGGAGAGATGTGGCGTATTTGAGTGATAAGTCGTCGGAAGCACCAAGAAAACGGAAAGAAAAATCGAAGAAACGTGAAAAAGACGCAAACGCGCCGAAACATCCAGCGACAGCATTCATGTTGTGGCTCAATGAAAGCCGTAAACGGATTATGGATGAAAACCCTGGTATCAAAGTAACTGATGTCGCTAAGAAGGGCGGAGAGATGTGGCGTGATTTGAGTGATAAGTCGGAATGGGAAGAAAAACCTCGTAAAGCTAAAGAAGAATACAATAACGCGATGAAGAAATACAAAGAAAGTGGTGCAGCAGATGAATTCAAGCAGAAGAAAAAACAAGCTGATAAAGAACGTAAAGCTGCTGATAAGAAGAGCAAGCCTGCCCCTGCCAGTAAGAAAGCCAAGAATACTAGTGCTGGTTCAGGATCTGCATCATTCAAAAACAAGGAATATATTGAAGATGATGATAGCTCCTCAGATTCCAGTAGTGAAAAGAAGGAGAAAagtgaaaagaagaaaaaaaaatattatAATGACAACTCTAAAAAGGAGAAGGCCAAACATTCCTCCTCTGAAGCAGCATCGTCAGGCTCAGGTGAAGACAGCGGCAGTGACAGTGATTAG
- Protein Sequence
- MERRWKVDDSWKLGRENYVPFLHSDSNKSPVIVMYILSFNRGNTTLRAREELRDKYEGKISKELSGPTYEVLAKIMKVVINRRVTGPGGFLGHHKTPAIACSYKAAAGYLYPLEKGFIYVHKPPVHIRFEEIASVNFARVGTSSTKSFDFEIELKSGNVHTFSCIEKGEYDKLFDYITSKKLHVKNTGKNDKALYDDDFGDSDTEKEPDAYLARVKAEAKERDSGDSDGSDESTDEDFNPDKAKESDVAEEYDTNPSSSEESDASNASGDSKKEKKKEKKPKKTITISEAPRKRKEKSKKREKDANAPKRPATAFMLWLNESRKRIMDENPGIKVTDVAKKVGELWRRDVAYLSDKSDKALYDDDFGDSDTEKEPDAYLARVKAEAKERDSGDSDGSDESTDEDFNPDKAKESDVAEEYDTNPSSSEESDASNASGDSKKEKKKEKKPKKTITISEAPRKRKEKSKKREKDANAPKRPATAFMLWLNESRKRIMDENPGIKVTDVAKKVGELWRRDVAYLSDKSDKALYDDDFGDSDTEKEPDAYLARVIAEAKERDSSDSDGSDESTDEDFNSDKAKESDVAEEYDTNPSSSEESDASNASGDSKKEKKKEKKPKKTITISEAPRKRKEKSKKREKDANAPKSPATAFMLWLNESRKRIMDENPGIKVTDVAKKVGELWRRDVAYLSDKSDKALYDDDFGDSDTEKEPDAYLARVIAEAKERDSSDSDGSDESTDEDFNSDKAKESDVAEEYDTNPSSSEESDASNASGDSKKEKKKEKKPKKTITISEAPRKRKEKSKKREKDANAPKSPATAFMLWLNESRKRIMDENPGIKVTDVAKKVGELWRRDVAYLSDKSDKALYDDDFGDSDTEKEPDAYLARVIAEAKERDSSDSDGSDESTDEDFNSDKAKESDVAEEYDTNPSSSEESDASNASGDSKKEKKKEKKPKKTITISEAPRKRKEKSKKREKTQTRRKVQRQHSCCGSMKAVNGLWMKTLDKALYDDDFGDSDTEKEPDAYLARVIAEAKERDSSDSDGSDESTDEDFNSDKAKESDVAEEYDTNPSSSEESDASNASGDSKKEKKKEKKPKKTITISEAPRKRKEKSKKREKDANAPKRPATAFMLWLNESRKRIMDENPGIKVTDVAKKVGELWRRDVAYLSDKSDKALYDDDFGDSDTEKEPDAYLARVIAEAKERDSSDSDGSDESTDEDFNSDKAKESDVAEEYDTNPSSSEESDASNASGDSKKEKKKEKKPKKTITISEAPRKRKEKSKKREKDANAPKRPATAFMLWLNESRKRIMDENPGIKVTDVAKKVGELWRRDVAYLSDKSSEAPRKRKEKSKKREKDANAPKHPATAFMLWLNESRKRIMDENPGIKVTDVAKKGGEMWRDLSDKSEWEEKPRKAKEEYNNAMKKYKESGAADEFKQKKKQADKERKAADKKSKPAPASKKAKNTSAGSGSASFKNKEYIEDDDSSSDSSSEKKEKSEKKKKKYYNDNSKKEKAKHSSSEAASSGSGEDSGSDSD
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -