Hnum000309.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Heliconius numata
Gene Symbol
-
Assembly
GCA_016802625.1
Location
JAEBDU010013054.1:2140-5062[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 0.69 70 4.9 0.3 2 23 129 151 128 151 0.93
2 16 0.0049 0.49 11.7 0.8 2 23 174 195 173 195 0.97
3 16 0.00034 0.034 15.3 0.0 1 23 199 221 199 221 0.98
4 16 0.0019 0.19 13.0 1.5 1 23 226 249 226 249 0.97
5 16 0.0001 0.01 16.9 2.0 2 23 287 309 286 309 0.96
6 16 0.024 2.4 9.5 6.3 1 23 315 337 315 337 0.98
7 16 1.4e-06 0.00014 22.8 5.5 1 23 343 365 343 365 0.98
8 16 0.0016 0.16 13.2 0.9 1 23 473 496 473 496 0.92
9 16 0.19 19 6.7 0.1 2 23 523 545 522 545 0.95
10 16 0.049 5 8.5 2.4 1 21 593 613 593 615 0.94
11 16 0.018 1.8 9.9 2.0 1 23 620 643 620 643 0.98
12 16 0.13 13 7.2 0.2 2 23 651 673 651 673 0.95
13 16 0.00015 0.015 16.4 7.0 2 23 681 702 681 703 0.95
14 16 0.002 0.21 12.9 1.0 1 23 709 731 709 731 0.98
15 16 3.2e-05 0.0033 18.5 4.3 1 23 737 759 737 759 0.99
16 16 3.3e-05 0.0033 18.5 4.2 1 23 765 788 765 788 0.98

Sequence Information

Coding Sequence
ATGCACTGGGAAAACTGGGAAAAGAATTTTGAAGTACGTCAAAAGGGCATAAGCAACGAATCTGAAGAGACAGCAAAAAAAGTCAAGGAAATCAAAAGTAACACGCTAAAAAAGAGTCGCACTCCTAAAAAGAAAGTCGACGAAAAAGGCATGCAAGAAGTAGAAAAGCACCGAAAAAATTTTGTAGAAGTAATAACATATTCAAATGCAACGCCTATTCGTTTTAAAGGCGATATAGGTTACGGATGTTACTTTTGTTCAGAANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNATAACAAAACATGACAACGACAGCATTATACAAGTTGCGAAAGATATGCGTATATATACACTTAAATTAGATGTAACGGCTTTGCAATGTTGCATATGCCAATTAGATATATCAACGATAGAGGAACTGATGAATCATCTTGTGAAAGAGCACCAACGTGTCATTTACGTAGACATCAAAAATCATATGGTTCCATTTAAATTTGAAAATGAGGATTTGAAATGTGCCATATGTTTAGCAAAATTTATGAAATTCAGAAATTTAACTGAACACATGAACACACATTATAGAAATTACGTGTGTGACGTGTGCGGCGCTGGCTTCGTGAACCGTGACATTCTGCGCAGTCATCTCAGAATTCATAAAATAGGCGACTTCACTTGCGATTTCTGCACAAAAACGTTTAACACTCTAGTGAAGAAACAGTCCCATATAAACATAGTACACAAAAAAATGTACATGACAAGAAAGTGCGGATTTTGTAACGAACATTTCGATGATTATCACAAGAAAAACGACCACTTGACGAAGTTTCATGGCGTTGATTTAGTTATCTTAAAATGTGATCTGTGCGAAAAAACTTTTATCAACCAAAATCGGTTTAAGCGTCATGTTAGAAAAGATCATCTCATGGAAAGAAATCATCAATGTCAACTTTGTGATATGAAATTCTTTTGTGGTGAAAATTTAAAAAAACATATGCGGACGCACACTGGAGAGAAGGACTATCACTGCAGTATATGCACCAAGTCTTTTGCACGCAAGTTTTCTTTAAAAAAACACTTGCGAACACATTCTAAGAATTCTAAAGGACGTAAAACTTGCAAAGTAACTCCTGATACATATTTAATTATAAAGGAATCTGACACGGATGCTGACCGTGATCCCACCGAAACTGTATATTTTGAAGAATTTAAGAGTGTTCGCAAATTAACTAGAAAAAGAAAAATAACAGTGGACAGTGAACTCACTATGAAAAAGAAAGCTAAAGTAACGATAGGATCTAAAAAAATTAAATTAAAACCAATTAAAGAATTATCCAAACATCATCACAACATAAAAGAGATACTCCAGTGTTCCAACACAACACCTATACACGGCAAATGTGATCTGGGCTACTTGTGCTGCTATTGCACTGAACAGTTCCCAGATCCAGCCGATTTGAAAAAACACACAATACAACTGCACAGGAATGGAATTAAACCGACTTTCTTTCAAAAGAGAGATTTACAGAAATTTTACGTCAAAGTCGACATCACTGGATTGCATTGCAATATTTGCGCGGAAGATATAGAGGATTTGGATAAGTTGATCGATCACCTAAGAACTGTGCATGATAGGAAAATATATACAGATANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCGTATATACTAAATTCAAAATGCTTCTGGAGCACATGCATAAACACTGTAGAAATTTTATATGTGAACTGTGTGGTGTCGGATTTTTTAATCGTAGATCGTACATAAATCACCAGAAGTGTCACGTGGTGGGAGAATATAAATGCGACCGATGCGGCAAGCTCTTCGATAATGTTCAAAAAAGAAATCAACACTTTAGGACCGTTCATGTCCACGAGTACAAACTAAATAGATGCGGATACTGCAATGAGAAGTTTGCTGGGTACCGAACTAAAGCTGAACATTTGAGAATTGTTCACGGCGTTGGATCTGAAACGGCCAAATGCCAAGCTTGTGAAAAGAGCTTTTGTAATAAAGACTCTTTAAGAAAACATATCAAAAGACACCATTTGATGGAGAATCAATACAGCTGTACATTGTGTGAAATGAAATTCTTTGCTAAGAGAAATTTATCAGAACATATGGTGACACATACGAAAATCCGTCCGTTTCAATGCAACGTCTGCTTCAAGAAATATGGGCGGAAGCACACATTACGAGAACACATGCGAATACATAACAACGACAAGCGCTACAAATGCGAACACTGTGGGGTGGCTTTTGTGCAAAAGTGCAGTTGGCGACGACATATGCAATCGAAACACGATGACCAGCTTTAA
Protein Sequence
MHWENWEKNFEVRQKGISNESEETAKKVKEIKSNTLKKSRTPKKKVDEKGMQEVEKHRKNFVEVITYSNATPIRFKGDIGYGCYFCSEXXXXXXXXXXXXITKHDNDSIIQVAKDMRIYTLKLDVTALQCCICQLDISTIEELMNHLVKEHQRVIYVDIKNHMVPFKFENEDLKCAICLAKFMKFRNLTEHMNTHYRNYVCDVCGAGFVNRDILRSHLRIHKIGDFTCDFCTKTFNTLVKKQSHINIVHKKMYMTRKCGFCNEHFDDYHKKNDHLTKFHGVDLVILKCDLCEKTFINQNRFKRHVRKDHLMERNHQCQLCDMKFFCGENLKKHMRTHTGEKDYHCSICTKSFARKFSLKKHLRTHSKNSKGRKTCKVTPDTYLIIKESDTDADRDPTETVYFEEFKSVRKLTRKRKITVDSELTMKKKAKVTIGSKKIKLKPIKELSKHHHNIKEILQCSNTTPIHGKCDLGYLCCYCTEQFPDPADLKKHTIQLHRNGIKPTFFQKRDLQKFYVKVDITGLHCNICAEDIEDLDKLIDHLRTVHDRKIYTDXXXXXXXXXXXXXXXXXXXXXXVYTKFKMLLEHMHKHCRNFICELCGVGFFNRRSYINHQKCHVVGEYKCDRCGKLFDNVQKRNQHFRTVHVHEYKLNRCGYCNEKFAGYRTKAEHLRIVHGVGSETAKCQACEKSFCNKDSLRKHIKRHHLMENQYSCTLCEMKFFAKRNLSEHMVTHTKIRPFQCNVCFKKYGRKHTLREHMRIHNNDKRYKCEHCGVAFVQKCSWRRHMQSKHDDQL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00457411;
90% Identity
iTF_00782043;
80% Identity
-