Hnum028516.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Heliconius numata
Gene Symbol
BCL11B
Assembly
GCA_016802625.1
Location
JAEBDU010000038.1:2839901-2848177[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.27 28 6.2 0.3 3 23 115 135 113 135 0.96
2 13 0.0015 0.15 13.3 2.8 1 23 238 260 238 260 0.99
3 13 0.027 2.7 9.3 4.7 1 23 265 288 265 288 0.94
4 13 1e-05 0.0011 20.1 0.4 2 23 449 470 448 470 0.97
5 13 0.00058 0.058 14.6 2.1 1 23 476 498 476 498 0.98
6 13 0.097 9.8 7.6 0.2 1 23 593 615 593 615 0.98
7 13 0.0019 0.19 13.0 2.0 1 23 621 643 621 643 0.95
8 13 2e-05 0.002 19.2 0.5 1 23 649 671 649 671 0.97
9 13 0.00029 0.03 15.5 3.0 1 23 680 702 680 702 0.99
10 13 0.00019 0.02 16.1 0.8 2 23 749 770 749 770 0.97
11 13 0.026 2.6 9.4 5.9 1 23 787 809 787 809 0.95
12 13 2.1e-06 0.00021 22.3 0.7 1 23 815 837 815 837 0.98
13 13 4.5e-07 4.5e-05 24.4 3.1 1 23 843 866 843 866 0.98

Sequence Information

Coding Sequence
ATGAACAGCAATGCAACAGAAGTGGATCCTTTAAGTTCACAATCACAATATAGTTTAAATAATTTCCACAATTTTGAGAGTTATGATAACTTGCATTACCCATATACAGTTAATGTAGAACAATATCAAAATGCTTATAATTATTATAACAAACCCCAATCTAATATGAAAAACTCACAAGAAAATGCAAATAATGAAAATAGTGAAATAAACAAAAATGATGTCAAAAAAACAGATAATAAAGATATATCAATACCAAATATTGGTAAACAAAAGATTAAAAAAGAACGAAGTAAATATTTTTCTGAAAAAATAACAGAAAAGGATTTTCCATTTTATGGTTGTGCTCTGTGCAATTTATCGTATCAAACATTACATGAGTTAGATACTCATGTTCTTATACATAAAGAAAGGGTAACCAGTTATGATTTAAGAATTAAGAACCAAATGAAAAAACGGAAATTAAAGAAGGAAATGAAGAAAAACAAGAAATTAAAGAAAGCAATTAAAACTGAAATTGATTTAGAAATTGAAATAAAACCTGAAGATGGCTATATAGGTAATAAAAAAGCTACAGAATTCATAAATAATGGTGAATCAGATAATCAAAGTTTGAAAGAAAATAAATTAGATATTAAAACAGATAAAAAAAAAGTCACAGATAACACAAAAGCAACAGATAAGGCAAAAGATGATGAATTACAGAAAATATATAAATGTTTTGCATGTCAAAAGCAATTTACTCTAAGTTATTATTTGAAACTTCATGTTAGATCGCATACAGAAATAAGATATCAATGTAGAATATGTTATAGGTATTTTTCTAGATTTGAATTCTTAACACGACATTTTGATAAAAAGCACCCGGATGATAAATTAGAAGGAGAACCATATGATTACAACGCAATACTGCCATATTTAAAAGAATTAGAAGAACAAATGCGTGAAAAGAAAGAGAAAGAAGCGGAAAAAAAAACAGAAGATGTTTGGGCTGAAAATAATACTAATAAAGAATTTAATATACAAATAGAAGAAGTCAAAGTCGATATGAATATAGAAGTTAAGGAAGAGAATGATACTTGTGACGATAATGATGTAATTAATGAAGTTTTTAATGATGATCATGATGAAAATAAAGCTGATATAAAAATAGATGTGGTTAAAGAAGAGGATGATGTGAAAGAGGAGGATAATATGAAAGAGGAGGATGATGTGAAAGAGGAAGATGATATGAAAATGGAGGATGATATCCAATCAGACGACGACTATTTCCCATCAAACACGTGGGCTTCCACACCTAAAATCGAAACCCCACCGTCTCCCCAACAAAAGCAGGACAAACTAAACTGTCCACAATGTGGCAAGAGAGTGTCCACGGTCTCCTACATGAGGGTTCATATGAGGACGCATACTGGGGAAAGGCCCTTCAAATGCTATATATGTAACGCGGGATTCATTACGAGCAGTAAGATGCATAGACATGTGTTGACTCATCCTGAGTCGTGGGATGAAGATGGAATAAAACCGGAAAAGGAAGAAATAAAATCGGAAATAGAAAAAGATGGCGACGACGATGATGATGACCCCGATGATAAGAAACCGTTACAAAAAATGAAGGAAGCCCTAGCGAAGTTCTCCAAAAAACCAAAGAACACGGAGAAGAAGAAGAAAATGTATCAAAAACGACCTCATGCCTGTGAATTTTGCCACAAACGATTCTTGCATTTGGAAACTTTACAAGTACACAAAAACTGTCACGAGGGCGAAGAAAGAAAATACAAATGTAATTTTTGCCTCACCGAGTTAGAAAATGAAGCTGCACTTAAAACTCATGAAGCCACCCACGAGGGACCAAAGCCGTACTTGTGCACTATATGCGGGAAAAATTATAAGAAACGTGAGACTATGATATACCATAGAAAAAATCACAAACCCGACAAAGAGTTCATATGTGACATATGCACAAAATCTTTCAACGCACAGAACAAATTGCAAAGGCACATAATATCACATAAAGTTGATAAATTTATACTTAGATACGAGTGTCCTGTCTGTGCGCACATGTTTAACACGAAATATCATGTGCAAATGCACTTGAATACACATCAGAAGGAGGGGCTAATACAAGAGGAAAATCGAAACGAAATACTAGCGATGGTGTTACAAAATGCTCGTAAAATACCCAAAAAGTCAGATACATCGACCTCCCTAACTGAAATAGTGCCTTCTGACGAGCGAAGTCGCGTATGCAACATATGTGGAGAAATGTTCCAACATTTTTACTATTTAGAGGAACATTTAAAAAGCCACGGCTCGAAAATCGCCATAGAAGATAACGAGAAAATCGAAGAAAAAAAACATATATGTAAAATTTGTAATAAAGGATTCAAATTACACTATTATCTAAAATTACATAGTTTCACTCATACTAAAGAGAAACCGTTTATTTGTCAGCAATGTGGTAAGGGGTTTATAACCCGGGGAAAATTAAAGAGACATTTGGAAACGCATACGGGGTTGAAGAAATATCAATGTCACATTTGTTATAAGTTTTTTACAAGACCCAGTTATTTGAGGATTCATGTTAGAACCATACATGGTACGCAAGATTATAATTTCAGAATGGATAAGCGTTATGAGTTTACAGTTCCGTTGGTTAACGAATGA
Protein Sequence
MNSNATEVDPLSSQSQYSLNNFHNFESYDNLHYPYTVNVEQYQNAYNYYNKPQSNMKNSQENANNENSEINKNDVKKTDNKDISIPNIGKQKIKKERSKYFSEKITEKDFPFYGCALCNLSYQTLHELDTHVLIHKERVTSYDLRIKNQMKKRKLKKEMKKNKKLKKAIKTEIDLEIEIKPEDGYIGNKKATEFINNGESDNQSLKENKLDIKTDKKKVTDNTKATDKAKDDELQKIYKCFACQKQFTLSYYLKLHVRSHTEIRYQCRICYRYFSRFEFLTRHFDKKHPDDKLEGEPYDYNAILPYLKELEEQMREKKEKEAEKKTEDVWAENNTNKEFNIQIEEVKVDMNIEVKEENDTCDDNDVINEVFNDDHDENKADIKIDVVKEEDDVKEEDNMKEEDDVKEEDDMKMEDDIQSDDDYFPSNTWASTPKIETPPSPQQKQDKLNCPQCGKRVSTVSYMRVHMRTHTGERPFKCYICNAGFITSSKMHRHVLTHPESWDEDGIKPEKEEIKSEIEKDGDDDDDDPDDKKPLQKMKEALAKFSKKPKNTEKKKKMYQKRPHACEFCHKRFLHLETLQVHKNCHEGEERKYKCNFCLTELENEAALKTHEATHEGPKPYLCTICGKNYKKRETMIYHRKNHKPDKEFICDICTKSFNAQNKLQRHIISHKVDKFILRYECPVCAHMFNTKYHVQMHLNTHQKEGLIQEENRNEILAMVLQNARKIPKKSDTSTSLTEIVPSDERSRVCNICGEMFQHFYYLEEHLKSHGSKIAIEDNEKIEEKKHICKICNKGFKLHYYLKLHSFTHTKEKPFICQQCGKGFITRGKLKRHLETHTGLKKYQCHICYKFFTRPSYLRIHVRTIHGTQDYNFRMDKRYEFTVPLVNE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00621411;
90% Identity
iTF_00781206;
80% Identity
-