Hnum004499.1
Basic Information
- Insect
- Heliconius numata
- Gene Symbol
- LZTR1
- Assembly
- GCA_016802625.1
- Location
- JAEBDU010010538.1:1183-6047[+]
Transcription Factor Domain
- TF Family
- BTB
- Domain
- zf-C2H2|ZBTB
- PFAM
- PF00651
- TF Group
- Zinc-Coordinating Group
- Description
- The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 4 1.5e-16 7.4e-14 52.6 0.0 4 109 17 156 14 157 0.85 2 4 6.3 3.1e+03 -0.9 0.0 78 107 157 186 154 188 0.81 3 4 3.4e-17 1.7e-14 54.7 0.0 9 96 250 337 246 352 0.87 4 4 0.29 1.4e+02 3.4 0.1 77 106 352 381 341 384 0.81
Sequence Information
- Coding Sequence
- ATGTTGTCAAACTACCCGCGTTGTACCCTCCATGACGACTTCGGTCGCATCCTCAAGTCGCAGCAGTTCTGCGACGTCACGCTGCTGCTGGGCAGCGAGCAGACGGCCGTTCTGGCGCACCAGGCCATGCTAGCGGCGCGATCACAGTACTTGAGGGCTAAGATTAAGGAAGCAAAAGAAGAACTCGCAAAGCGTATAGAACGTATAGCATCAGGCGAGGAGGAACCTACAGCGGAATGTTCGTACAAGTCACGTCCACAGCTCACTGTGAATTTACCTGAAGCGACCCCCGAAGCTTTCCGAATGGTCCTCAATTATATTTATACGGATAGAATCGACCCTACTGAGAAAGATGAGGACCCAGCATCGCCAGCAACGATCCTTTTAGTGATGGAAGTACTTCGGCTAGCTCTAAGGTTAAACATTCCACGCCTACGCGGGCTTTGTGCCCGCTACCTCCGCGCCAACCTCTGCTATAGCAACGTGCTGCAAGCGCTCCATGCGGCTCATCACGCTAATTTGACATGTATTAAAGAGTATTGTCTGAGGTTTGTCGTGAAAGACTACAATTTCACAGCAATAGTGATGTCATCGGAGTTCGAGCAAATGGATCAACGATTGATGGTTGAAGTGATACGTCGTCGTCATCAACCGTCAAACAAAATGCCTGCCAACGAACAGGAAGAGGAAGTTATTGGTACAACACTGGAACAAGACATGTGCGTGTTCGTGAGCGGCGGCGGTGCGGAGCTCGCCGACGTTAAGCTCCGCGTGGCGGGCGCGGCGCGGCCCGCACACAGATCTATATTGGCAGCTCGAGCGGCGTATTTCGAAGCTATGTTTAGATCTTTCTCGCCGCAGGATAATGTTGTTAATATTCAAATCTGTGATACGGTGCCGTCAGAGGAGGCTTTCGACTCTCTCCTTCGTTACATCTACTATGGAGACACTAACATGCCCACTGAGGACTCACTTTATTTATTCCAAGCACCTATTTATTACGGTTTCACGAACAATCGCCTCCAAGTGTTCTGCAAACACAATCTACAAAGCAACGTGTCGCCGGAAAACGTGCTGGCCATTCTGCAGGCGGCCGACCGGATGCGCGCGCAGGATATAAAGGAGTACGCGTTGAAAATGATCGTTCATCATTTTGAATCTGTCGCCCGTCAAGATGCAATCAAAAATTTGGCGCAACCATTGCTAGTGGATATTATATGGGCATTAGCAGAAGAACCACGTTTCGACACTCCACTACCGCTCCAACCGAGATCCTTGCCATCTTCATCATCAGCTGATACCCTCACCGATGACCCTGAATATATACGTTATAGATCTGCCAAATAA
- Protein Sequence
- MLSNYPRCTLHDDFGRILKSQQFCDVTLLLGSEQTAVLAHQAMLAARSQYLRAKIKEAKEELAKRIERIASGEEEPTAECSYKSRPQLTVNLPEATPEAFRMVLNYIYTDRIDPTEKDEDPASPATILLVMEVLRLALRLNIPRLRGLCARYLRANLCYSNVLQALHAAHHANLTCIKEYCLRFVVKDYNFTAIVMSSEFEQMDQRLMVEVIRRRHQPSNKMPANEQEEEVIGTTLEQDMCVFVSGGGAELADVKLRVAGAARPAHRSILAARAAYFEAMFRSFSPQDNVVNIQICDTVPSEEAFDSLLRYIYYGDTNMPTEDSLYLFQAPIYYGFTNNRLQVFCKHNLQSNVSPENVLAILQAADRMRAQDIKEYALKMIVHHFESVARQDAIKNLAQPLLVDIIWALAEEPRFDTPLPLQPRSLPSSSSADTLTDDPEYIRYRSAK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00425567;
- 90% Identity
- iTF_00778830;
- 80% Identity
- -