Basic Information

Insect: Heliconius nattereri
Gene Symbol: IBTK
Assembly: GCA_013403645.1
Location: JAAIXI010000219.1:4648921-4662447[+]

Transcription Factor Domain

TF Family: BTB
Domain: zf-C2H2|ZBTB
PFAM: PF00651
TF Group: Zinc-Coordinating Group
Description: The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 7.3e-16 2.3e-13 50.4 0.0 6 79 543 614 538 618 0.91

2 3 1.5e-09 4.6e-07 30.1 0.1 9 107 731 833 726 836 0.80

3 3 4.8 1.5e+03 -0.6 0.1 79 106 837 864 831 867 0.87

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	7.3e-16	2.3e-13	50.4	0.0	6	79	543	614	538	618	0.91
2	3	1.5e-09	4.6e-07	30.1	0.1	9	107	731	833	726	836	0.80
3	3	4.8	1.5e+03	-0.6	0.1	79	106	837	864	831	867	0.87

Sequence Information

Coding Sequence: atgagTAGGACGGTAGAGGTAGATTGTACTAAGCGCTGTAAGTCTAGAGTTCATGGGCAGGTTTTGACTAGTGCCATAACAAAGAGATCTATTAGCGATGAATCTCTTGCCAGTTTTGTTAAGTCCACCTGTGCTAATTTTGCCAAAGCATTCGATTTTGAGGGTCGAACTGCTCTACATATGGCCGCATCGAGAGGTAGGAACGGTCTAATGGAATGGCTGATTCGTCATTCCTCTGACGCCTTCGTAAATGCACGCGACCGTGAATCTGGATATACTCCACTGCATAGAAGTATTTTCTATGGCCAAATTCATTCTGCTGTTAGTCTTATGAAACTtgGCGTAAACACGGACATCCAAGACAAAGACGACTATAAAGCAATAGAACACGCCACGCTCGATAAGCATTACATGTACCAGCAATCTGGCTCAGAGCCTTGCGACGCTTACGTATGGGGAAGTAACTCCAACTACACTTTGGGTACGGGATCGCAACAGCCCAAACAAGTGCCAGATCTGCTATCCTGTTTTAGTCGTACAAATGCTAATCTTAGACAGGTATGTCTCGGTAAATTCCATAGCGTATGGGTATGTGGTAACATCGACAATGGGGAAGTATGGTGTGCTGGTCAACCGGCTCGTGCTGGAGGCCCCCATACGACCGCACTGCGCCCTGTGCCTCTCAAACTGCCGGAACCATGTTTACAAGTCGCTATTACACTGACTTCTACTATTTTCTTACTACAAAGTGGTGCGgtAATCCAATACACATTAAACAACACAGAAAATCCAAGTCCATCATCAGTCAAGAGTCCAACAACTATAAAACTAGCGTCAGTCAAACCTCTAATAAAGATATCGCACCCGCTAGGCATCTGTGCAGGGCGGTCTCATGGTGTCGTGTGGAATAAAAACGCGGTTTTTACGTGGGGTACGAATTTGGGACAATTAGGCCATAGTCAGGAGGATAAAATTgtTGGCATgtccttaaataataaagaagaatCGTGCATTCAGTTGGTGGATGCGACAGACGCGGCCACAGTCATAACAACCAGCCGCGGTGATGTTTatcttttacataaatatttgtgcAAGAAAATTGCTATTAAgcAAATCAATCTCAAACAAGTGTGTGTTGAAGCAAAGGTTAATGAACAAGGTTCGTACTCAAGGGTGACAGTATTGCTTTTGACCAATGTTGGTCAACTCATGTTGTGGCAAGACACTACCAATAAACTAAcaagaTGCGTATTTGGATTAAATcaccaaattataataacgcaCGTGACCTTAACGCACGACGCCCTATATTTTACAACTAAACATGGCGACGCGTTCATTGGTTGTATTTCCCGTAAAACCGTTCAGCCAATCAGGAAAGAGaaagaaagagagagagataaTAAATCGGCTCTCGTCAGATTTTTAGAAAAGGATGACTGTACTTCTGCCAGAATAACCAAAATACCTAATGTGCATAGAGCTGTGGCGATATCGGTGGATAGTGAGGGATTGAATTATGCCTGTCTACAGATAAAACCAACATGTGGTTTGACATCTCTACCAGATTTGTCACCGTCGTGCCTATCCAAACATATGGAGTCACTCTTCGAGACCGCAGTTGAGGATGATATTTTACATGATGTTATATTTAagATAGGTTTAAAACAATACCCCGCCCATATATTCATAATCGCTTCAAGCAGCGACTACCTTTACAAACTGTATCAAGAATCCAACACAAATACGCACAAACCAACTATAGTATTAGATAATGTGCATCCAGAAGTTTTCGAAAGGATTCTAAAGTATATGTACACGGGAACCTGTGATGTAGCTGAGCTGGGACCCTGCGGATTAAAAATAAGGAGAGAAGATTTGAATAGCGGAAAGAAGGAGAATGTTGATACAGAAGAATATATTGaaaattCATCCGAAATATCAGCTTTCGAAGTATATAAAAACCAAGATAAAAAGAAGAATCGTCGTCGCAACACCGAAACGCCTCCACGCGTTCACCTCTACTGTGACCCTGTAAAACTGGTCCAAGCTACGGCTAAAAGACTTCACGTTATGGGCTTGCACAAACTGCTTGATAAGTTTTATTACAGAGACGGCACAGTGTGTCTCAAAGAAAGTGCAGTATACACTAAAAACGTCCTAACATGGGACCGAGATACATATCCAGAATTAGTAGATACAAATGTCTGTTCCAAAGACGGCATGCTGATATCGGCCCATAAATGTGTGTTAGCAGCCAgattggaatatttttatggaatgTTCATGCATTCTTGGACTGAGAGCAAACTTCTATCAAAAGTGACTTTACCAATAAATCATGGTATTCTCTTACCagtaataaatttcttatacaGGGATACTTGTCCAGAAGTTCAAAATTCAGATAGCATTGACTTTATTTGTAGCATGCTCATAGTATCCGATCAGCTTTTTATAAGCCGACTAAGAGAAATGTGCGAAATATCATTATCTAACTTAATAACTCTAAAGAACTGCACTGAAATCTGTCAATTTGCACACACATATAACGCAAGCCAATTAAAACAATGCTGTATGGAGTATATTTCGCTCAATATAGCTAGCATACTTGAAAATAGATCTTTGGACCACTTAGAAGGTGCCTTGTTAGAGGATATATCTAAAtactattgtaaatttaaccCGATAATGTCTTCCCGGGTGATAACGCCGTTTTTCAATTCGCCCAGCGATGAAACTATCGAGGATTGTACCAAAAGCTTGACTGTTGACTTAGAAATAATTGatgaagattttaaaaaggaCGATAGCATAGAAATaaccaaaaagaaaaaacagagAAAGATAGAGTATACAGAAAGTGAAAAGGCAAGAATGAGATATGAATCAGTGAGTTCTGTGACGTCATTAAATTTATCCCACGATACATCCGGAGATGTCACTTTGTCGCTTAGCGCTATACCAAAAAGTGCTGAAAAGAAATCTCGTGAAACAGAAAAATGGACAGAAGTGCCAACCTCCCAGCAAAAACAGCAAAAAGTTGTTCAAGCACGCCTTAAAGCTATATCCTCAGCTaaggatattttaaatgaaacgcCAGCAAActcttttacaaaattgtcaaaaaataattcatttagcGCCATTTCTCAAGAACCTGTTACACCAACAACTTCCCGTCAAATGTCAGTTTCCCCAAAAGAAACAGAATTTTGTTGGGGTCAAagtaatatgataataaatcacGTTGGTCCCAAGCTATCCCAAAAGCAGAGAAAGAAACTGGCATCAGAAACTGAACAGAATCCACAAACTTTGGACAATTACttgtcaaataaattaaatattggcaGTCCTCCTGACAAACCGAAAAATCCCTGGAAAATATGTCAAGCGCCAATCGCTCAAAGTAGCCCCAATAAACAAAATGCTatggaatttaataaaatattggctGATCAGAAAAAGCAAAAAGATGATTTCTCGAGAATCATGACTAAACCTTTGAACTTGACTCAGctTGAAGATAAAGCAATTGAAGAATTGGAACGTTTCTACAACATTCATGAAGCAGATGACGAACTGATAACAGTTAGACGCATAGAGCTGCAAGTAGCATCGCCACAATGGATACACACTGCCCCAAAGTGA
Protein Sequence: MSRTVEVDCTKRCKSRVHGQVLTSAITKRSISDESLASFVKSTCANFAKAFDFEGRTALHMAASRGRNGLMEWLIRHSSDAFVNARDRESGYTPLHRSIFYGQIHSAVSLMKLGVNTDIQDKDDYKAIEHATLDKHYMYQQSGSEPCDAYVWGSNSNYTLGTGSQQPKQVPDLLSCFSRTNANLRQVCLGKFHSVWVCGNIDNGEVWCAGQPARAGGPHTTALRPVPLKLPEPCLQVAITLTSTIFLLQSGAVIQYTLNNTENPSPSSVKSPTTIKLASVKPLIKISHPLGICAGRSHGVVWNKNAVFTWGTNLGQLGHSQEDKIVGMSLNNKEESCIQLVDATDAATVITTSRGDVYLLHKYLCKKIAIKQINLKQVCVEAKVNEQGSYSRVTVLLLTNVGQLMLWQDTTNKLTRCVFGLNHQIIITHVTLTHDALYFTTKHGDAFIGCISRKTVQPIRKEKERERDNKSALVRFLEKDDCTSARITKIPNVHRAVAISVDSEGLNYACLQIKPTCGLTSLPDLSPSCLSKHMESLFETAVEDDILHDVIFKIGLKQYPAHIFIIASSSDYLYKLYQESNTNTHKPTIVLDNVHPEVFERILKYMYTGTCDVAELGPCGLKIRREDLNSGKKENVDTEEYIENSSEISAFEVYKNQDKKKNRRRNTETPPRVHLYCDPVKLVQATAKRLHVMGLHKLLDKFYYRDGTVCLKESAVYTKNVLTWDRDTYPELVDTNVCSKDGMLISAHKCVLAARLEYFYGMFMHSWTESKLLSKVTLPINHGILLPVINFLYRDTCPEVQNSDSIDFICSMLIVSDQLFISRLREMCEISLSNLITLKNCTEICQFAHTYNASQLKQCCMEYISLNIASILENRSLDHLEGALLEDISKYYCKFNPIMSSRVITPFFNSPSDETIEDCTKSLTVDLEIIDEDFKKDDSIEITKKKKQRKIEYTESEKARMRYESVSSVTSLNLSHDTSGDVTLSLSAIPKSAEKKSRETEKWTEVPTSQQKQQKVVQARLKAISSAKDILNETPANSFTKLSKNNSFSAISQEPVTPTTSRQMSVSPKETEFCWGQSNMIINHVGPKLSQKQRKKLASETEQNPQTLDNYLSNKLNIGSPPDKPKNPWKICQAPIAQSSPNKQNAMEFNKILADQKKQKDDFSRIMTKPLNLTQLEDKAIEELERFYNIHEADDELITVRRIELQVASPQWIHTAPK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01507342;
90% Identity: iTF_00457344;
80% Identity: -