Basic Information

Insect: Heliconius melpomene
Gene Symbol: -
Assembly: None
Location: Hmel212001o:2181812-2186091[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.037 2.6 8.8 0.3 5 23 348 366 347 366 0.96

2 11 0.0052 0.36 11.5 0.1 3 23 374 394 372 394 0.95

3 11 0.038 2.6 8.8 0.8 2 23 403 424 402 424 0.94

4 11 3.4e-05 0.0023 18.4 2.7 2 23 429 450 429 450 0.98

5 11 0.00062 0.043 14.4 4.3 1 23 456 478 456 478 0.98

6 11 0.00036 0.025 15.2 0.5 1 20 482 501 482 503 0.94

7 11 4.9e-05 0.0034 17.9 0.1 1 23 536 559 536 559 0.96

8 11 7.8e-05 0.0054 17.2 1.4 1 23 578 600 578 600 0.98

9 11 8.7e-06 0.00061 20.2 3.3 1 23 606 628 606 628 0.98

10 11 0.0022 0.15 12.7 0.3 3 23 636 656 634 656 0.98

11 11 3.3e-06 0.00023 21.5 0.9 1 23 662 685 662 685 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.037	2.6	8.8	0.3	5	23	348	366	347	366	0.96
2	11	0.0052	0.36	11.5	0.1	3	23	374	394	372	394	0.95
3	11	0.038	2.6	8.8	0.8	2	23	403	424	402	424	0.94
4	11	3.4e-05	0.0023	18.4	2.7	2	23	429	450	429	450	0.98
5	11	0.00062	0.043	14.4	4.3	1	23	456	478	456	478	0.98
6	11	0.00036	0.025	15.2	0.5	1	20	482	501	482	503	0.94
7	11	4.9e-05	0.0034	17.9	0.1	1	23	536	559	536	559	0.96
8	11	7.8e-05	0.0054	17.2	1.4	1	23	578	600	578	600	0.98
9	11	8.7e-06	0.00061	20.2	3.3	1	23	606	628	606	628	0.98
10	11	0.0022	0.15	12.7	0.3	3	23	636	656	634	656	0.98
11	11	3.3e-06	0.00023	21.5	0.9	1	23	662	685	662	685	0.97

Sequence Information

Coding Sequence: ATGAAGTGTTTTAACATGGAATCATGGTCGGATTTGTGTCGCTGCTGTCTTGCTCCAGATTCGGAAGTGTCACTTTTTGATGCCGAAGATAGTGTGCAAGAGAAGTTTTTGGAAATTACTACAATTGAGCCAAAACAAGATGATGGTTTACCTCAAAGGTTATGTAGTGATTGTTTTACATTAATGACATCAGCATATCAATTCAGGATGCAGTGCATGAAAGTAGACAAAGAGTTAAAACTTCAATTAGAATCCCTCATAAAACAAAATAAGGAGGATGAACTATCAGAAATGTCCTTTTCACAAATAGAAACCCAATTGAAAGCAAGTGAAGACATGACAATAGAAGATCTTGCTAAGGAATCATTCAAACAGCTTGAGTCTATAATAAAAAAGGAACCAAATGATAACGAAGATGACTTTTATTATGTAGTTGTTGTAGGTAACCCAAAAGATAACAAATCGGATGATGAGAAAAGTAAAGATAATATAACAACGGAACCTGTGATTAGAGAGGAGGAAGAAGTTGATAATGATGCAAGCCCAAGTTCAAATCAGTTTGAGAGCACAATCGATTCATTTCTTGTAACTAACCCAAAAGTGTCAATGCATGTACCAGACACAATTTTGGAAAATGAGGAAGTGGAAAATGACTTTGATCAACCAATGGATGTTGATGTCAATCATATGTCCCAAGATTTATCAATTAATGAAGATTCTCAAGAAAAAAACGAATATGCTATACCTTTAACACAAGATATGATAGACAACCTATCTAATTCTAAAAATTTCATCAAAATTTTAACTCCATCTGGAGTGGAAAAGACTATTTTAGTTAATGGTGATAGTGTAAAGTACTTAACAGGTACTGATACTATAAAACTTGAAAGTGATTCAATTCCACAGGAAGTAATATTGTATGAGGGTGATGACTCACAGTTCCAGTTAGTCAAATGTGATGGATCCGAGTTAGTAATTGAGTATGCGGATGATAGTCAAATTGCAACTATTTTACAACAAGAGGATGGCACTTTCTTATGTGACTGTGGTGAACAATTTGATGACTTGGAGACATATGAAAAACATCAATACAAACACAATCCAGCTGGAGACCATTTGTGTAATTTATGTGGTAAAGGGTTCGAATCTGCAGAGATTTTGACCGGACATATGTTAATACACAGCAACCCAACTGGCCCATTTGTTACTTGTCCGTTTTGCAATCAAAACGTTAAAAGGAGTAGTCTAACTCAACATATAAAATATATGCACAATAGTAAACCACAGTGTGATGTTTGTTGTAAGACATTTGCAAATCAAAATAATTTGAGACGTCACATGATGATACACAGTGGTATTAAAGAGTTTGAATGCGACATATGTAAAAAAAGATTCCATCAAAAAATAACTATGCAAACTCACAGACTTACGCATATAAGTCCCTTCACCTGCGGCCAGTGTGGTGTTAAATTCGAAAATAAAGGTGATTTAACACACCATAAAGTAACTGATGAATGCTCAAAATCTAGAATATGTAAAGTTAAAGAAGAATTAATGAAGACAGTCAAACAAGAAGTTACAACAGATGATGGCAAATTATTAGGTTACGCCTGTTCATTATGTAAAAAAATGTTTTCCGTCGAATCGGCGTTGGAACAGCATATAGAGAGTTCACACATTATTGAATCAGATGGACACCAAGATAAAAAAATTAATAAAACTAGCAAAAGGTTTGAATGTTGTATTTGCGGTAAAGGGTGCTCTAGCCAAGCCATGTTGATAATGCATGAAAGGGTCCATACAAATGAGCGGCCATTTCCGTGCCCACTTTGCTCTTTAAGATTTAAAACTAAAACTCATTTAAGAACTCATCAACTAACTCATACACGAGAAAAGAAATTTGGTTGTTCAGTTTGTATGAAGTTTTTTGCCTTAAAAGGTAACTTGGTAGTTCATTTGCGAACCCACACTGGTGAAAGGCCATATGTATGTTCAATATGCGGTGAGGCCTTCATAGATTCTAAATATCTTAAGAAACATAAGCAAAAGAAACATGCTATAGATAATGTACCGTGGGATAAGTATGAATAA
Protein Sequence: MKCFNMESWSDLCRCCLAPDSEVSLFDAEDSVQEKFLEITTIEPKQDDGLPQRLCSDCFTLMTSAYQFRMQCMKVDKELKLQLESLIKQNKEDELSEMSFSQIETQLKASEDMTIEDLAKESFKQLESIIKKEPNDNEDDFYYVVVVGNPKDNKSDDEKSKDNITTEPVIREEEEVDNDASPSSNQFESTIDSFLVTNPKVSMHVPDTILENEEVENDFDQPMDVDVNHMSQDLSINEDSQEKNEYAIPLTQDMIDNLSNSKNFIKILTPSGVEKTILVNGDSVKYLTGTDTIKLESDSIPQEVILYEGDDSQFQLVKCDGSELVIEYADDSQIATILQQEDGTFLCDCGEQFDDLETYEKHQYKHNPAGDHLCNLCGKGFESAEILTGHMLIHSNPTGPFVTCPFCNQNVKRSSLTQHIKYMHNSKPQCDVCCKTFANQNNLRRHMMIHSGIKEFECDICKKRFHQKITMQTHRLTHISPFTCGQCGVKFENKGDLTHHKVTDECSKSRICKVKEELMKTVKQEVTTDDGKLLGYACSLCKKMFSVESALEQHIESSHIIESDGHQDKKINKTSKRFECCICGKGCSSQAMLIMHERVHTNERPFPCPLCSLRFKTKTHLRTHQLTHTREKKFGCSVCMKFFALKGNLVVHLRTHTGERPYVCSICGEAFIDSKYLKKHKQKKHAIDNVPWDKYE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00160072;
90% Identity: iTF_00782029;
80% Identity: -