Hmel019318.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Heliconius melpomene
Gene Symbol
BCL11B
Assembly
None
Location
Hmel217001o:11821614-11831658[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 14 0.26 18 6.1 0.3 3 23 115 135 113 135 0.96
2 14 0.0015 0.1 13.2 2.8 1 23 238 260 238 260 0.99
3 14 0.00016 0.011 16.3 2.5 1 23 266 289 266 289 0.97
4 14 0.026 1.8 9.3 4.7 1 23 294 317 294 317 0.94
5 14 1e-05 0.0007 20.0 0.4 2 23 478 499 477 499 0.97
6 14 0.00056 0.039 14.5 2.1 1 23 505 527 505 527 0.98
7 14 0.094 6.5 7.5 0.2 1 23 622 644 622 644 0.98
8 14 0.0018 0.13 12.9 2.0 1 23 650 672 650 672 0.95
9 14 1.9e-05 0.0013 19.1 0.5 1 23 678 700 678 700 0.97
10 14 0.00028 0.02 15.5 3.0 1 23 709 731 709 731 0.99
11 14 0.00019 0.013 16.0 0.8 2 23 778 799 778 799 0.97
12 14 0.025 1.8 9.3 5.9 1 23 816 838 816 838 0.95
13 14 2e-06 0.00014 22.2 0.7 1 23 844 866 844 866 0.98
14 14 4.3e-07 3e-05 24.3 3.1 1 23 872 895 872 895 0.98

Sequence Information

Coding Sequence
ATGAACAGCAATGCAACAGAAGTGGATCCTTTAAGTTCACAATCACAATATAGTTTAAATAATTTCCACAATTTTGAGAGTTATGATAACTTGCATTACCCATATACGGTTAACGTAGAACAATATCAAAATGCTTATAATTATTATAACAAACCCCAATCTAATATGAAAAACTCACAAGAAAATACAAATAATGAAAATAGTGAAATAAACAAAAATGATGTCAAAAAAACAGATAATAAAGATATATCAATACCAAATATTGGTAAGCAAAAGATTAAAAAAGAACGAAGTAAATATTTTTCTGAAAAAATAACAGAAAAGGATTTTCCATTTTATGGTTGTGCTCTGTGCAATTTATCGTATCAAACATTACATGAATTAGATACTCATGTTCTTATACATAAAGAAAGGGTAACCAGTTACGATTTAAGAATTAAGAACCAAATGAAAAAACGGAAATTAAAGAAGGAAATGAAGAAAAATAAGAAATTAAAGAAAACAATTAAAACTGAAATTGATTTAGAAATTGAAATAAAACCTGAAGATGGCTATATAGGTAATAAAAAAGCTACAGAATTCATAAATAATGGTGAATCAGATAATCAAAGTTTGAAGGAAAATAAAATAGATATTAAAACAGATAAAAAAACAGTCACAGATAACACAAAAGCAACGGATAAGGTGAAAGATGATGAATTACAGAAAATATATAAATGTTTTGCATGTCAAAAGCAATTTACTCTAAGTTATTATTTGAAACTTCATGTTAGATCCCATACAGATGAAAAACCGTACACATGTCCCAGCTGTGGACAATGTTTTATAACTGCAAGTAAATTAGGACGTCATAATAAAAGATTTCATTTAGAAATAAGATATCAATGTAGGATATGTTATAGGTATTTTTCTAGATTCGAATTCTTAACACGACATTTTGATAAAAAACATCCGGATGATAAATTAGAAGGAGAACCGTATGATTACAACGCAATACTGCCATATTTAAAAGAATTAGAAGAACAAATGCGTGAAAAGAAAGAGAAAGAAGCGGAAAAAAAAACAGAAGATGTTTGGGCTGAAAATAATACTAATAAAGAATTTAATATACAAATAGAAGAAGTCAAAGTCGATATGAATATAGAAGTTAAGGAAGAGAATGATATTTATGACGATAATGATGTAATTAATGAAGTTTTTAATGATGATCACGATGAAAATAAAACTGATATAAAAATAGATGTGGTTAAAGAAGAGGATGATGTGAAAGAGGAGGATAATATGAAAGAGGAGGATGATGTGAAAGAGGAAGATGATATGAAAATGGAGGATGATATCCAGTCAGACGACGACTATTTCCCATCAAACACGTGGGCTTCCACACCTAAAATCGAAACCCCACCGTCTCCCCAACAAAAGCAGGACAAACTAAACTGTCCACAATGTGGCAAGAGAGTGTCCACGGTCTCCTACATGAGGGTTCATATGAGGACGCACACTGGGGAGAGGCCCTTCAAATGCTATATATGTAACGCGGGATTCATTACGAGCAGTAAGATGCATAGACATGTGTTGACTCACCCTGAGTCGTGGGATGAAGATGGAATAAAACCGGAAAAGGAAGAAATAAAATCGGAATTAGAAAAAGATGGCGACGACGATGATGATGACCCCGATGATAAGAAACCGTTACAAAAAATGAAGGAAGCCCTAGCGAAGTTCTCCAAAAAACCAAAGAACACGGAGAAGAAGAAGAAAATGTATCAAAAACGACCTCATGCCTGTGAATTTTGCCACAAACGATTCTTGCATTTGGAAACTTTACAGGTACACAAAAACTGTCACGAGGGTGAAGAAAGAAAATACAAATGTAATTTTTGCCTCACCGAGTTAGAAAATGAAGCTGCACTTAAAACTCATGAAGCCACCCACGAGGGACCAAAGCCGTACTTGTGCACTATATGTGGGAAAAATTATAAGAAACGTGAGACTATGATATACCATAGAAAAAATCACAAGCCCGACAAAGAGTTCATATGTGACATATGCACAAAATCTTTCAACGCACAGAACAAATTGCAAAGGCACATAATATCACATAAAGTTGATAAATTTATACTTAGATACGAGTGTCCTGTATGTGCGCACATGTTTAACACGAAATATCATGTGCAAATGCACTTGAATACTCATCAGAAGGAGGGGCTAATACAAGAGGAAAATCGAAACGAAATACTAGCGATGGTGTTACAAAATGCTCGTAAAATACCCAAAAAGTCAGATACATCGACCTCCCTAACTGAAATAGTGCCTTCTGACGAGCGAAGTCGCGTATGCAACATATGTGGAGAAATGTTCCAACATTTTTACTATTTAGAAGAACATTTAAAAAGCCACGGCTCGAAAATCGCCATAGAAGATAACGAGAAAATCGAAGAAAAAAAACATATATGTAAAATTTGTAATAAAGGATTCAAATTACACTATTATCTGAAATTACATAGTTTCACTCATACTAAAGAGAAACCGTTTATTTGTCAGCAATGTGGTAAGGGGTTCATAACCCGGGGAAAGTTAAAGAGACATTTGGAAACGCATACGGGGTTGAAGAAATATCAATGCCACATTTGTTATAAGTTCTTTACAAGGCCCAGCTATTTGAGGATTCATGTTAGAACCATACATGGTACGCAAGATTATAATTTCAGAATGGATAAGCGTTATGAGTTTACAGTTCCGTTGGTTAACGAATGA
Protein Sequence
MNSNATEVDPLSSQSQYSLNNFHNFESYDNLHYPYTVNVEQYQNAYNYYNKPQSNMKNSQENTNNENSEINKNDVKKTDNKDISIPNIGKQKIKKERSKYFSEKITEKDFPFYGCALCNLSYQTLHELDTHVLIHKERVTSYDLRIKNQMKKRKLKKEMKKNKKLKKTIKTEIDLEIEIKPEDGYIGNKKATEFINNGESDNQSLKENKIDIKTDKKTVTDNTKATDKVKDDELQKIYKCFACQKQFTLSYYLKLHVRSHTDEKPYTCPSCGQCFITASKLGRHNKRFHLEIRYQCRICYRYFSRFEFLTRHFDKKHPDDKLEGEPYDYNAILPYLKELEEQMREKKEKEAEKKTEDVWAENNTNKEFNIQIEEVKVDMNIEVKEENDIYDDNDVINEVFNDDHDENKTDIKIDVVKEEDDVKEEDNMKEEDDVKEEDDMKMEDDIQSDDDYFPSNTWASTPKIETPPSPQQKQDKLNCPQCGKRVSTVSYMRVHMRTHTGERPFKCYICNAGFITSSKMHRHVLTHPESWDEDGIKPEKEEIKSELEKDGDDDDDDPDDKKPLQKMKEALAKFSKKPKNTEKKKKMYQKRPHACEFCHKRFLHLETLQVHKNCHEGEERKYKCNFCLTELENEAALKTHEATHEGPKPYLCTICGKNYKKRETMIYHRKNHKPDKEFICDICTKSFNAQNKLQRHIISHKVDKFILRYECPVCAHMFNTKYHVQMHLNTHQKEGLIQEENRNEILAMVLQNARKIPKKSDTSTSLTEIVPSDERSRVCNICGEMFQHFYYLEEHLKSHGSKIAIEDNEKIEEKKHICKICNKGFKLHYYLKLHSFTHTKEKPFICQQCGKGFITRGKLKRHLETHTGLKKYQCHICYKFFTRPSYLRIHVRTIHGTQDYNFRMDKRYEFTVPLVNE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00621411;
90% Identity
iTF_00781206;
80% Identity
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