Hnig006050.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Hartigia nigra
Gene Symbol
ZBTB41
Assembly
GCA_031001745.1
Location
JARPRG010000321.1:103947-105290[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 6.6e-05 0.0044 17.4 0.3 1 23 92 114 92 114 0.95
2 12 2.9e-07 1.9e-05 24.8 1.9 2 23 121 142 121 142 0.98
3 12 5.2e-06 0.00035 20.9 5.8 1 23 165 187 165 187 0.95
4 12 0.00016 0.011 16.2 4.8 2 23 193 214 192 214 0.97
5 12 0.00061 0.041 14.4 0.1 1 23 219 241 219 241 0.98
6 12 4.4e-06 0.00029 21.1 0.9 1 23 249 271 249 271 0.98
7 12 0.038 2.5 8.7 2.0 1 23 277 300 277 300 0.94
8 12 0.00013 0.0089 16.4 0.3 3 23 313 333 311 333 0.96
9 12 7.5e-07 5e-05 23.5 1.8 1 23 339 361 339 361 0.96
10 12 1.9e-08 1.3e-06 28.5 0.2 1 23 367 389 367 389 0.98
11 12 1.5e-07 1e-05 25.7 0.9 1 23 395 417 395 417 0.98
12 12 0.00034 0.023 15.2 1.7 1 21 423 443 423 444 0.96

Sequence Information

Coding Sequence
ATGTTCGCCAAGCTCGACCTGGTGAAGAAAGATGCGGAGCAGACAGAAGTAGAGAAATTAAAGGACGTCGAAGAGTCGAGGGCAACGAGGTCGTCAAGAGCGCCAAAAGCGCCAAAAGCGTCGAGGGTATCGGCGATTCCGAGTTCCGAAACGAGTCCGAACGCTGACGAAATAAAGCAGGAAATCGAGGAGgaggcggaggaggaggaggaggaggatgatgaggaggaggagggggagggggaggaggaggaggaagattTGCCGCTGGCCTTCCAATGTAAAACCTGCGGTGTCTTTTTCAACTCGCAGGGTCTCCTGGAGAATCACGAGATCGAGCACAAGGGTAAGCGGAAGAATACGTGCAATCAGTGCGGCCGCGTCTTTAGGACCTACGTTAATCTGCGAAAGCACATAAAGAAACACGCGGGACGCAAACGCAAGGCCGTCGGGCGCCCCCTGAAGCTCAAGAAGGAAAAGCCCGAAGTCGAATTTCTCTGCAAAACCTGCAACAAGGTTTTTCGGCACAAGAGCAATTACCAAAAGCACCTGCTGCGCCACACCGTCGGCGACCTCACCTGCAAGCACTGTCCGAAGAAGTTTCGATTGTTTAGGGACTTGACGCGTCACGAGAAGACTCATTTCTATCCGAGCTACATGTGCAAGGAGTGCGACTACGAGACGACTGTCCTCGCCGCCCTGAGCATTCACATGCTGCGACACACCGACAAGGCGGACCTGCCCTTCAAGTGCAACGAATGCGAGAAGCGATTCCGCAAGGCGATCGACCTCCAGGAACATTACAACATCCATTCCGGCGAGAAGCCTTTCGTCTGTCAGCTCTGCGGCAACGCGTTCTACCTGCGACGGCAGCTCTCGGCTCATTGTCGTCGGATGCATCCCGAGATGAAGGCGAACAAGGTCACGAGCACAGCCTGCGACATCTGCGGCCGCGTCCTAGCGACCAAGCGCTCTCTCTTCCGGCACAAAGAAAGTCACAACCCGACGAAGCTCTACCTCTGCGACTACTGCGGCAAGAGTCTGAGTAGCGCCGAGCACCTCAAGAAGCATCGACGCATCCACACTGGCGAGAAGCCCTACGTCTGCGACATCTGCGGCAAGGGCTTCACCGATTCGGAAAACTTGCGAATGCACAGAAGGGTTCACACTGGCGAGAAGCCCTACAAGTGCGACCAATGTCCCAAGGCCTTCTCGCAGAGGTCCACCCTGACGATTCACAGGCGAGGTCACACGGGCGAGCGACCCTACGTCTGCCAAATCTGCCATCGTGGCTTTTCCTGCCAGGGCAACCTGACTGCCCATCAGAAGTCCACTTGTGTCTGA
Protein Sequence
MFAKLDLVKKDAEQTEVEKLKDVEESRATRSSRAPKAPKASRVSAIPSSETSPNADEIKQEIEEEAEEEEEEDDEEEEGEGEEEEEDLPLAFQCKTCGVFFNSQGLLENHEIEHKGKRKNTCNQCGRVFRTYVNLRKHIKKHAGRKRKAVGRPLKLKKEKPEVEFLCKTCNKVFRHKSNYQKHLLRHTVGDLTCKHCPKKFRLFRDLTRHEKTHFYPSYMCKECDYETTVLAALSIHMLRHTDKADLPFKCNECEKRFRKAIDLQEHYNIHSGEKPFVCQLCGNAFYLRRQLSAHCRRMHPEMKANKVTSTACDICGRVLATKRSLFRHKESHNPTKLYLCDYCGKSLSSAEHLKKHRRIHTGEKPYVCDICGKGFTDSENLRMHRRVHTGEKPYKCDQCPKAFSQRSTLTIHRRGHTGERPYVCQICHRGFSCQGNLTAHQKSTCV