Basic Information

Insect: Hartigia nigra
Gene Symbol: TFDP2
Assembly: GCA_031001745.1
Location: JARPRG010000125.1:189968-192981[+]

Transcription Factor Domain

TF Family: E2F
Domain: E2F_TDP domain
PFAM: PF02319
TF Group: Helix-turn-helix
Description: This family contains the transcription factor E2F and its dimerisation partners TDP1 and TDP2, which stimulate E2F-dependent transcription. E2F binds to DNA as a homodimer or as a heterodimer in association with TDP1/2, the heterodimer having increased binding efficiency. The crystal structure of an E2F4-DP2-DNA complex shows that the DNA-binding domains of the E2F and DP proteins both have a fold related to the winged-helix DNA-binding motif. Recognition of the central c/gGCGCg/c sequence of the consensus DNA-binding site is symmetric, and amino acids that contact these bases are conserved among all known E2F and DP proteins.
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 4e-24 1.8e-20 72.4 0.1 2 65 172 252 171 252 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	4e-24	1.8e-20	72.4	0.1	2	65	172	252	171	252	0.97

Sequence Information

Coding Sequence: ATGACGCAGCAAAATAAAACGATGAATTTCCTCATACATGACGCCAACGGACATCCTCAAGTGATCAAAGTTGTGCAGAGCACACCTAATAAGACACTTGGTGGATTAGTTGGCACCACAAACACAAGTAACCTCAAGGTTTTCAAGAGTCCTGGTCAAGATCCTCAGGTTTTATCATCTGGTACACAAGTCCTTAGGACTATCAGTTTGCAAACTCCTTCAACTCCTGGCCAAAGGTTGGTTACAATACCATTACAAAATGCAAAGATGCCTACTGTTAAACCAGGGGAGTCAGTGATGACAAAAACTATACAGTTAACGTCAGCTCAAATGaGTGATATAAAGCAGGCTATAGTGTCTCAACAGCAACAAACTGGCAGTCAGCAAGTTATTAAAGATTCAACTGGAAAGACATTCATCAGTCCCATTTTAGATCACACTGGCTCTAGAAAACGTCAGGATACAGAGAGTGGCGATTTTGTCCCAGAcaaaagaaggaaaacagAAAAGGTTGGAAAAGGTTTGAGACACTTTTCCATGAAAGTGTGCGAGAAGGTTAAGAAAAAAGGTACAACGTCTTACAACGAGGTGGCCGACGAACTCGTCGGCGAATTCACAAATCCAGCTCATATAAACTCCTTGACAGATCAGCAATATGATCAAAAGAATATCAGAAGGCGTGTTTATGACGCACTCAATGTTCTCATGGCGATGAACATCATctcgaaagagaagaaagagatcaGATGGTTAGGATTACCGACAAATTCGCTTCAAGAGTGTCTCGCTTTggagaaagacaagaaaaagaaaatcgaaaagatCAAAGCAAAAACGCAACAGCTACATCAATTAATTCTTCAACACATCTCCTTTAAGAATCTCGTTGAGCGAAATCGCTTTAACGAAAGTTTTGAAGGTCCACCTAAGCCAAACTCAGCAATACAGCTGCCTTTTCTCATAGTCAACACCAGCAAAAAGACTGTCATAGACTGCAGCATTTCGAATGACAAAACCGAGTACCTGTTTAACTTTAACGATAAGTTCGAAATCCATGACGACATAGAAGTTCTAAAACGCATGGGTCTGGCTTTTGGTTTGGAAAAAGGAGAATGCTCCGAAGAGGATTTACGAAAAGCAAAATCAATGGTGCCCAAATCTCTTGAGAAATACGTAGAACAACTCGCATCTGGCGATCTGGAAAAGTTTATACCAGTGACCATTCCCGGACCGAGTACTTCGATGGACGACTTGGAAATCAAATTGGAAGGTTCTGGTTCACGGCCGCCGTCCTCGTCGCACACATCTTTATCAGAAGATCCTCTCTCGCCACCTTCGCAATACTACTCCgaggaagaggacgaggacgaggagagTGACCAGGATGATCAGGTCGACAGTGATCTCGAGGTTAACTAG
Protein Sequence: MTQQNKTMNFLIHDANGHPQVIKVVQSTPNKTLGGLVGTTNTSNLKVFKSPGQDPQVLSSGTQVLRTISLQTPSTPGQRLVTIPLQNAKMPTVKPGESVMTKTIQLTSAQMSDIKQAIVSQQQQTGSQQVIKDSTGKTFISPILDHTGSRKRQDTESGDFVPDKRRKTEKVGKGLRHFSMKVCEKVKKKGTTSYNEVADELVGEFTNPAHINSLTDQQYDQKNIRRRVYDALNVLMAMNIISKEKKEIRWLGLPTNSLQECLALEKDKKKKIEKIKAKTQQLHQLILQHISFKNLVERNRFNESFEGPPKPNSAIQLPFLIVNTSKKTVIDCSISNDKTEYLFNFNDKFEIHDDIEVLKRMGLAFGLEKGECSEEDLRKAKSMVPKSLEKYVEQLASGDLEKFIPVTIPGPSTSMDDLEIKLEGSGSRPPSSSHTSLSEDPLSPPSQYYSEEEDEDEESDQDDQVDSDLEVN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01539398;
90% Identity: iTF_01198458; iTF_01199196; iTF_01130602; iTF_00298096; iTF_00296562; iTF_00295031; iTF_00293506; iTF_01394918; iTF_01475238; iTF_01472968; iTF_01474474; iTF_00253355; iTF_01473707; iTF_00292079; iTF_00251857; iTF_00294257; iTF_00295796; iTF_00297335; iTF_00254872; iTF_00292730; iTF_00254108; iTF_00291324; iTF_00252606;
80% Identity: iTF_01198458; iTF_01199196;