Hsal005545.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Harpegnathos saltator
Gene Symbol
bab2
Assembly
GCA_003227715.1
Location
NW:284081-289141[+]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 2.5e-24 5.2e-22 77.5 0.0 3 98 275 366 273 368 0.94

Sequence Information

Coding Sequence
ATGCAAACAAGACAGTACTCGGGCTCGTGTCGGGATCCAATAGGGCACAAACGCAGCATCATCGTGACGGCCTCCACGGACGGTATCAAGGAAGACGTCGTGATGAAGCAGGAACCGGAAGATGAAGAAGATTGTTatctcgacgacgactcgatgcccgcgtcgccgccgccgccgccggcacgCACACCAACGTCGACGCTGTTACCAACACAATCGTCATcctcgtcatcatcgtcgtccgGTAGACACGGCAGCATCACGCACCGCGTGCGCTCCCATACAGGCAGCCTGCGCGCCATGGCGAACCCGAGTGCTGTCTGGGCGCACTTCGACCTGTGCACTAACGATCCGTTGCGCGCACAGTGCCGTATCTGCGGGGCGGTTGTGGTTAGAGGTGGCGCGAACCCGCGTCAGTGTGGCACAACGAATCTTCACCGGCATCTGCGAGTACATCACGGCGGCAGATTGATCGGCAGACGATATCACGTATTACAGTCAACGTCCCAAGGAAACGCGACTGCTAAAACTATAAGGATAGCACAGTCCTTGGTGAGACCTCATTTTCGTAACATTGCACCAGCGCCACTGTCCCAGCAGCAGCAAccgcagcaacagcaacagcaacaacaaccaCGACCAACAAAGACTCTTGTGTTAAAAACTATTCCATTGAAAGTGAAACAAGTCGCGCCTACAACCATAAAGATGCCACCACGACAAACTAATCAAGGATTACCGCACAATATTGTACATCAACAACCCACAGAAGTTTGCTTGAGGTGGAATAGTTACCACAGTAACATGCAGAACAGTTTCCCGTCGTTGCTGGATTCAGAACAGTTCGTCGATGTGACTCTAGCGTGCGAAGGGCGGTCCTTAAAGTGTCACAAGATGATCCTGTCCTCTTGTAGCGACTATTTGGCAGATTTGTTACGGGAGAATCCGTGCCAACACCCCATCATCTTGATGAAGGATCTGAAATTCTGGGAAGTGGAGGCACTGGTTAAATTCATGTACCGTGGGGAGGTCAATGTCGCCCATGATAAACTCTCACAATTGTTGAACGCTGCTGAGGCATTGCAAGTGAAAGGATTGGCTGGTCCGAGTCCATCATCCCAAAGCGCAAAGCCACCGCTACTCATACCTCAATCAAAGCCATTGTCGTCGCAACCTGTAGTTCCTAGAGGCATTACGGAATCCAAAGAGAATAAGGCGTCGCCCTCGGGAGTCTCTACGCCTTCTAGTCCTAAGCGCGCGCAGAAGCGGCAACAGTCTGAACCTTTAGAACCAAGGCCTTTTACCAAAATACGTTTGCAGCGGCCCGTCACGCCGTCGTCACCCTGTCCAACCGTGAAAATGGAGCCCTTGGACATACCTCTCAGCCCGACCGAGATATTCTCCGAGAATAACGAGGAGGCCGTCACGCCGTCCTCGGACTTGGACAAGCTTATGAATCTGCACGAAGAGGACGATCCAGGTGGCGAAGAAGTTGGCAACGAAGTCAGGAGATTACACTTTTGCGAACTGCCAGCTCCGCCAGATTTAAATGACAGCGAGGACCAAATGGAGTTTGTACCTACCGATTTCCTAGAGCagcagcaggaggaggaaaTTGCCGAGGAACCAGAATCGAATTGTAATAAGGATAATAGTAAAAAAGATTCTCCCGACTACACGCCAGCCGACGACGCCGGGGAAGACGACGGAGTCACGGAAAGCGAAACTTCGACGCAGCcgtcgaaggagaagaaagtGACATAG
Protein Sequence
MQTRQYSGSCRDPIGHKRSIIVTASTDGIKEDVVMKQEPEDEEDCYLDDDSMPASPPPPPARTPTSTLLPTQSSSSSSSSSGRHGSITHRVRSHTGSLRAMANPSAVWAHFDLCTNDPLRAQCRICGAVVVRGGANPRQCGTTNLHRHLRVHHGGRLIGRRYHVLQSTSQGNATAKTIRIAQSLVRPHFRNIAPAPLSQQQQPQQQQQQQQPRPTKTLVLKTIPLKVKQVAPTTIKMPPRQTNQGLPHNIVHQQPTEVCLRWNSYHSNMQNSFPSLLDSEQFVDVTLACEGRSLKCHKMILSSCSDYLADLLRENPCQHPIILMKDLKFWEVEALVKFMYRGEVNVAHDKLSQLLNAAEALQVKGLAGPSPSSQSAKPPLLIPQSKPLSSQPVVPRGITESKENKASPSGVSTPSSPKRAQKRQQSEPLEPRPFTKIRLQRPVTPSSPCPTVKMEPLDIPLSPTEIFSENNEEAVTPSSDLDKLMNLHEEDDPGGEEVGNEVRRLHFCELPAPPDLNDSEDQMEFVPTDFLEQQQEEEIAEEPESNCNKDNSKKDSPDYTPADDAGEDDGVTESETSTQPSKEKKVT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00769826; iTF_01261955; iTF_00015521; iTF_00181414; iTF_01261928; iTF_00016138; iTF_00181452; iTF_01476366; iTF_00016784; iTF_01476402; iTF_00014836; iTF_00016821; iTF_00016182; iTF_00182075; iTF_00015484; iTF_00014877; iTF_00182110; iTF_01477060; iTF_01477027; iTF_01523525; iTF_00128353; iTF_00126850; iTF_00128388; iTF_00126885; iTF_01523497; iTF_00127632; iTF_00127601; iTF_00126133; iTF_00126102; iTF_01015965; iTF_01015997; iTF_00730214; iTF_00730182; iTF_01354758; iTF_01354726; iTF_00730892; iTF_00730919; iTF_00265133; iTF_00265165; iTF_00264414; iTF_00264448; iTF_00729453; iTF_00729483; iTF_01229137; iTF_01229165; iTF_00867602; iTF_00867558; iTF_00109940; iTF_00109970; iTF_00385717; iTF_00385680; iTF_01355542; iTF_01355585; iTF_00868984; iTF_00869035; iTF_01245337; iTF_01245362; iTF_01423065; iTF_01421665; iTF_01422338; iTF_01423035; iTF_01421693; iTF_01422367; iTF_01409355; iTF_01407555; iTF_01405930; iTF_01405900; iTF_01409324; iTF_01406670; iTF_01406708; iTF_01408404; iTF_01408440; iTF_01407516; iTF_01520438; iTF_01520399; iTF_00885277; iTF_00765778; iTF_00885309; iTF_00452684; iTF_00452706; iTF_00417744; iTF_00417711; iTF_01254961; iTF_01254923; iTF_01477777; iTF_01477731; iTF_00898967; iTF_00898899; iTF_00280696; iTF_00280675; iTF_01099352; iTF_01099378; iTF_01077626; iTF_01077589; iTF_00280093; iTF_00280068; iTF_01087358; iTF_01087331;
90% Identity
iTF_00769826;
80% Identity
iTF_00769826;