Basic Information

Gene Symbol
Hivep1
Assembly
GCA_963082715.1
Location
OY720457.1:35532185-35539336[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 8 0.00015 0.037 16.7 0.9 1 23 267 289 267 289 0.98
2 8 0.098 25 7.8 3.7 1 21 295 315 295 319 0.83
3 8 0.33 85 6.2 0.2 2 20 556 574 555 576 0.92
4 8 5.6e-06 0.0014 21.2 2.1 1 23 1246 1268 1246 1268 0.99
5 8 2.9e-06 0.00074 22.1 4.2 1 23 1274 1298 1274 1298 0.92
6 8 1e-05 0.0026 20.4 1.0 3 23 1815 1835 1814 1835 0.97
7 8 0.0014 0.37 13.6 1.6 1 23 1841 1865 1841 1865 0.91
8 8 0.0016 0.41 13.4 2.8 1 23 1883 1907 1883 1907 0.93

Sequence Information

Coding Sequence
ATGGAAATCTCTGGGAACAAATATttgcataaaaaatttaaaaaacaaacaagttgtaGTCCTGTTTACAACGTAGAAGATAAGAATGATAACAGTGTATTGGTCGCCACCGCAATCACCACCGACAACAACGGAGTGAGATCAACTTCTAGTGAAGAGGAATCtgttaattttatgttatttaaggACAATAAACCTATAGGAAGTGTGCCAAATTATAAAAGTACAAATTGTGACGGTAGTTTAAGTATTGAATCACAAGCTAGCTATAGAAGTGTTGAAAGAACCGCGAACGTGAATGTTAAATTAGATAATCAGTCTTCCATATCAAATGTAGAAGTAAGTGTAAACATAGCGGCAAGTAGCAGTGTAACAAAGAAATTACAACCAGAACCACAAGACTCATTCAAACAATATCGATCTTCTGACGATCCGAAAATTAGATCGCTGGACCACCAATCCATTTCGACATCAACCGTAACTAGCTgcatatcaaaaataattactaCAACTACAAATAGTTTGATAAATCATGATTTCAAAGAGAACACTgtaagaaataattttagttttgatACTAAACATAATATTTCCGAACCAATTTCGAAAATTGAGAAGTCTTCCATTTTAGATACCGTATATTCTAAATCTAGTTTAAGATCAGAAAAGTCAAATGCAGCAGGTATCAAATTAGAAGTACAAGAACATTTCATGGTCGGAAGAGCTGATTCCGATGGTATTAATTTCACAGAAAACATTCAAGAAAAGAAAAACTGCACAGAGTCCTCCGGAGGAAAATATGTTTGCACTTATTGTAATTTAGCATGTTCAAAGCCCAGTGTTTTACAAAAGCATATTCGCGCCCATACAAATGAGAGACCATATCCATGTATTAGTTGCGGATTTAGTTTTAAAACAAGATCTAATTTATACAAGCATTGTAGATCTAGAACCCACGCAAATAGAGTTATGGGCAACAAGCATGTACAAGTTGGTCAAATGGAAACAATAGATGTTGACGGTACTTCAGATAAAAATGAAGATCGGTCGGATTATACGGAAGAATTAATGGAAACCATAATTACTCCAGTAAAtgagaaacaaatgaaaatgtttGGAAATTCTGTGCAGTTAAGTAAAGATGTTACGTTTGCACCCGACCAAAAGAATATTTGGgaacaaaaaacaaaaccataTAAACCACGTTTCCATACCGCAAAAATGTTTTACgaggaaaataaattaaaagaaaatgatgcAAAATTAGATAACGTTTGTATTGTCCCACCAAATAATTTGAAATCACCTATCCCGGAAGTTGTAAAATATAAAGTGGAGATGCAGGAACCACAAGTTAGGAGTACTCCTGATTTATTAAAACTTAGAATTAATGAACTTATAAACAAGAATAATTCTATAGTTAATTCTGATGAAGCTATGGTAATTAGAAGAAGAAATcttgaaaatattattgaaaataataatgaatatttatctCCTCATCATAATCAGTGGCATCATCATCAACAAACCGAGTACAGAAATGATGAACCACTGAATTTGACCGCTAAAAACAGGAAACGCTGTTTAAGTGAAACagataattcaaataaaagtttaattaaagaattattgcttaaaaatttaagtagcGATCCTAATCTTCAATGCCAGTACTGCAAAATGATTTTTCAAACAGTTACAGAATTAGAaatgcataaaataaaatattgtaatgcGAAACATAGTAATATAAGATACGCAAGAAGTAGTTCTGTAAATGTGGCTTCTATATTAACAGGAAATAAAAATGCTTTTGATAGTATTCCTCATATGCAACATACAACGTTTCCACTAAAATCGCCAGGCCCATTTTTGGGAAAAACTAGGTTAATTGACAGTGAAAAAGCAGgtgaaaaatatagaacattttcTTTTGATGATAATGTCATTATGCATCACAGTCAGTCCGATTCTCCTAGttatagtaaatatattatGCATTCACCTGTTGGTACTTACCCTTTGTCTCcacagataaaaaaaaatcctattaaacTATTTGGCGGAGAAGTTAAAATTACACAAACTTCTGGGGAAACCAGAAGTTTTAAAATAGAGtcagaaagtataaataaaatagaagaaCCACATAATTTCATGGAATTTAGTGGAAATTTAAGCGAAAATCTAGTTATAAAATCAACTTTACAGTCTGGAGGAACAGtactacaaaataaaacaaactacAGTCCAAAAATGGACAGCTTACCTTCTCCTAATATAATTAGAGTTTATGAGAATTCAGATATGCCTACAgccaatttaaatttatcaatattaaatgataaaacTAAATTTACGTACGATAAGATCTCACAACCAAATATTAGACAAAATGATAAACTTTTAATTCTGGCAAATAATGAAATGTTGAAGAGAAGGTTTCCGGTAAGAGATAAAATTGAAACAAGCTCTTCTGAGAACATGCGTAATTCCGATATTATTCGAAATCCCGACACTAAATCGGAAAGTGAAAAAGATAAAGAATTGTACAAATCTAATTTAATGGACTTCGGTCAAAAAGCAGTGAAACTCTTAGCTCCTAATTTAAAACCACCAAACTTAACTATACCAGGTATACCAATACCTTCTGCACCTAGTGATAAAATCATGTCTTCTCCAATAGTTACAATTGCGcctttagaaataaatactagTACAATGGATAGAGATGCTTTCATAGATAGGCAACACCAAGAAAATCTCAATTTTGCTAAGAAACAAATTTCATTACAACAACGAATGGCAGAAGTATCTCAACCACAAACTGTTTTGAACCCAATGAATATTGTAGTGAATGGAAAAATAATTCGATACGTTCCTGGAATGCCGGGACCAATTGTTGCGGATACTCCAGAAATACTATCTCCTGGAAGATTatctgaaaataataaactgTTGAAGTCTCCCCGACCTATAGAAGAATCCCGAGAGACTAAAGATACACCCGAAACTGCAACtggattttcaataaataataatcagttTGAACGAAGAACACCAACCATAATTGTAGATCAACATGAAAGCAAATTTTCAGAACCGAAGATACAATGTACAGAAAGAATAAATAACTTACCTAGCAGAGTTTCGGAAAACAAAATTAGTTCAACTTTAACAGCTACAAGTCCGGACAAAACATCTAAGGAAGAATCGAAAAAATTCGTTCGTCCTACTAGTTTGGCATTAAAGCCAAATTCTGTAGCTTTTAAAAGCCATCATGGGTTAACTCCCACGATGTTTAATCAAGCTTTAATCAGCCCTGATACGCCAAGAGTCGCAAAGAAATATTGTCAGCAATATCTAAATGGAAATTACTTCAGTTATCTAGGGTtgaaaagttctacaaaatcaGTTTATTGTACATTAAATAAAACCCAACCATTTTATGTGAAGCATTTCAAGAAATTAAGCATGTATTCCGAATGGAGACAACAAGAAAGTAAATTGGATAGTTTGAGTGTTAGTTCTTATGATTCTAGACAAAGGCAGCAAAAATATACGATGGCAGGACAAGCGAAAGCAGACTTAATCGCCCATTCAAGTTACAAGtttGTGAAATCCGAAAGCCCAATGACGAAAGACgaaagtacaaataaaactTCATCACTTCTTGGTGGTTATGAATCTAATGAAGACTACACATATATTAGGGGTAGAggtCGAGGCCGTTATGTTTGTGATCAGTGTGGAATTAGATGCAAAAAACCATCTATGTTAAAGAAACACATTAGGACACATTCCGATGACCGACCTTACACTTGCGAACATTGTAACTTCAGctTTAAAACTAAAGGAAATCTAACTAAACATATGAAAAGCAAAGCACATTCTAAGAAATATGCAGCTACTAGCAGTACATCGACTCAAAATAGTATAACTACAAGTTCCGAATCTGAAGAAAGCGACGCTGAAAGTAGCGatgaATCAACCAGACTACAAGAGCATGAAGCAGCGCGCTGTCTTCTTTCATTATCTCAAAAAACTACTTCAACTCAACCTTTAAACACCTATCTGGAATCGACAAATTCATGTTCTTCAGTAGCGTCAGTAACTTCAGTGACGTTTAACTTATcagatttttctaattttttaaaagatgataaatttttgaaaaattcagaACAAATAAATCAAGTTACTAACACGAATTTTGCCAAAAACAAGATTTTGGATGAAGTACCGGTTTGTTTCAACGCTACCAAACACTTAACCGAAGTGTTTGACGTTACTGCCTGTACTAGTCAGGAATCTACAAATGTTAGTCAATATTTGGGAAAATCTTCTACAGTAAGACCTTTAACGTATCCGTATCAGCAAACACAACTTGATTTAGATTCGAAAAGTAATGAACATACAGACAACATTCCAAAAATATCAGTGCCTCATGAAATTAATCacagaaatattattaaacccCTAGATAGCAAAGTTGTTAATTTAAGAGAACCTCCTCAAGATCAAAAATATCCTCATATAAAGGTGAAGAGTGTAGAAGAAGTTAAATATGTTCCAAATAGTCAAAAAATAAGCTTAccaattgtaagacaagatttTTCATCGCAAAATGTCGAAGGAAACCTTCCAGCAAATATAGtatttagaaaaagaaaattgtcTTCTTCCAATGCAGTTCATAGTAAAGTACAACGAAACGAGCCAATAGAATCCACTTCAAAAGCGACAGCAGTAGATCTTTCCATGCCGATTATACAGGATTCACCGATTTTAGATTTATCACCTGCAACACTAAATGGAGAAGCATCATTATTGTTTAAtgatgcttcaaataatagtgataactttaataataaattaaatatttctattccTAAAAGAACATTACTATTAAATCATGAAAACCAAGTGAATCCATCTAGAACAGTTGAAGTGATATCAGATACACCAGTAATATACAACGTAAATAATGAAAGAATTAGCGAAccgttaattatttataaccaGGTACAAAAACCACGTCATAATAGTTTTTCCGAATCAAATAGTAGCGAAACATTTTCACAAAACAGCGATACAAATGATCGAATAATAGGAAAAATATCCGACAAACCTGATAACTCGTTGCCATCTGATAAAGAAATGTACAAATCCAATATGCATACCGAAATTGCACGAAGTCAGTCTAAAACTCCAGAATGCGGAGAGCAGGACCAATCAGCTATGCAAACTCTTGCAGAAATTGCCATAAAGCAAGTAAAGTTAGAGAAGAATATACTCGCCAAAAATGTTGCTTCAGAATATTTAAAGTTGGCATTAAATAATGAAGGGAGTAATCCTGAgggaaatatgaaaaaatatgcTGCTAGCACAAAAGAATCTGTTAGTGACTTGATGGTTAAACCAGAAGAAAgcaaaaattgtacaatttgtTCGAAGAATTTCAGCAAACCATCGCAGCTAAgGCTACATATGAATATTCATTACTTAGAGCGACCATTCCGGTGTGAGCCATGTTCAACTAGTTTTAGAACCAGAGGACACTTACAAAAGCATGAAAGAAGTGCTGGTCATCATAATAAGTTGTCATCGTCACCCGCGTTATCGTCGCAAGAACCACGGCCTTTTAAATGTACAGATTGTAACGTTGCATTTAGGATACACGGACATTTAGCGAAACATTTACGATCGAAAATGCACATAATGAAACTTGAATGTTTAGCAAAAATTCCTTTTGGCCTATATGCCGAGTTAGAACGAGCGAATAGTTTACTAACAGAAATTAATACAACGGATGGGGATTTATGTTTAGAAAGTTTGAAGATTTTGGCGAGGAAATTATTCAGTAACGATCCAAATAAGTTGGACCAGTTAGGTAATTTACCTGATACTAGAGACagctaa
Protein Sequence
MEISGNKYLHKKFKKQTSCSPVYNVEDKNDNSVLVATAITTDNNGVRSTSSEEESVNFMLFKDNKPIGSVPNYKSTNCDGSLSIESQASYRSVERTANVNVKLDNQSSISNVEVSVNIAASSSVTKKLQPEPQDSFKQYRSSDDPKIRSLDHQSISTSTVTSCISKIITTTTNSLINHDFKENTVRNNFSFDTKHNISEPISKIEKSSILDTVYSKSSLRSEKSNAAGIKLEVQEHFMVGRADSDGINFTENIQEKKNCTESSGGKYVCTYCNLACSKPSVLQKHIRAHTNERPYPCISCGFSFKTRSNLYKHCRSRTHANRVMGNKHVQVGQMETIDVDGTSDKNEDRSDYTEELMETIITPVNEKQMKMFGNSVQLSKDVTFAPDQKNIWEQKTKPYKPRFHTAKMFYEENKLKENDAKLDNVCIVPPNNLKSPIPEVVKYKVEMQEPQVRSTPDLLKLRINELINKNNSIVNSDEAMVIRRRNLENIIENNNEYLSPHHNQWHHHQQTEYRNDEPLNLTAKNRKRCLSETDNSNKSLIKELLLKNLSSDPNLQCQYCKMIFQTVTELEMHKIKYCNAKHSNIRYARSSSVNVASILTGNKNAFDSIPHMQHTTFPLKSPGPFLGKTRLIDSEKAGEKYRTFSFDDNVIMHHSQSDSPSYSKYIMHSPVGTYPLSPQIKKNPIKLFGGEVKITQTSGETRSFKIESESINKIEEPHNFMEFSGNLSENLVIKSTLQSGGTVLQNKTNYSPKMDSLPSPNIIRVYENSDMPTANLNLSILNDKTKFTYDKISQPNIRQNDKLLILANNEMLKRRFPVRDKIETSSSENMRNSDIIRNPDTKSESEKDKELYKSNLMDFGQKAVKLLAPNLKPPNLTIPGIPIPSAPSDKIMSSPIVTIAPLEINTSTMDRDAFIDRQHQENLNFAKKQISLQQRMAEVSQPQTVLNPMNIVVNGKIIRYVPGMPGPIVADTPEILSPGRLSENNKLLKSPRPIEESRETKDTPETATGFSINNNQFERRTPTIIVDQHESKFSEPKIQCTERINNLPSRVSENKISSTLTATSPDKTSKEESKKFVRPTSLALKPNSVAFKSHHGLTPTMFNQALISPDTPRVAKKYCQQYLNGNYFSYLGLKSSTKSVYCTLNKTQPFYVKHFKKLSMYSEWRQQESKLDSLSVSSYDSRQRQQKYTMAGQAKADLIAHSSYKFVKSESPMTKDESTNKTSSLLGGYESNEDYTYIRGRGRGRYVCDQCGIRCKKPSMLKKHIRTHSDDRPYTCEHCNFSFKTKGNLTKHMKSKAHSKKYAATSSTSTQNSITTSSESEESDAESSDESTRLQEHEAARCLLSLSQKTTSTQPLNTYLESTNSCSSVASVTSVTFNLSDFSNFLKDDKFLKNSEQINQVTNTNFAKNKILDEVPVCFNATKHLTEVFDVTACTSQESTNVSQYLGKSSTVRPLTYPYQQTQLDLDSKSNEHTDNIPKISVPHEINHRNIIKPLDSKVVNLREPPQDQKYPHIKVKSVEEVKYVPNSQKISLPIVRQDFSSQNVEGNLPANIVFRKRKLSSSNAVHSKVQRNEPIESTSKATAVDLSMPIIQDSPILDLSPATLNGEASLLFNDASNNSDNFNNKLNISIPKRTLLLNHENQVNPSRTVEVISDTPVIYNVNNERISEPLIIYNQVQKPRHNSFSESNSSETFSQNSDTNDRIIGKISDKPDNSLPSDKEMYKSNMHTEIARSQSKTPECGEQDQSAMQTLAEIAIKQVKLEKNILAKNVASEYLKLALNNEGSNPEGNMKKYAASTKESVSDLMVKPEESKNCTICSKNFSKPSQLRLHMNIHYLERPFRCEPCSTSFRTRGHLQKHERSAGHHNKLSSSPALSSQEPRPFKCTDCNVAFRIHGHLAKHLRSKMHIMKLECLAKIPFGLYAELERANSLLTEINTTDGDLCLESLKILARKLFSNDPNKLDQLGNLPDTRDS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00769146; iTF_01105084;
90% Identity
iTF_01105084;
80% Identity
-