Hrub036900.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Harpalus rubripes
Gene Symbol
-
Assembly
GCA_963082715.1
Location
OY720454.1:64426493-64433854[-]

Transcription Factor Domain

TF Family
MBD
Domain
MBD domain
PFAM
PF01429
TF Group
Unclassified Structure
Description
The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 9 0.067 7.7e+02 2.1 0.0 35 59 489 519 487 571 0.76
2 9 0.045 5.2e+02 2.6 0.0 36 59 701 743 699 780 0.66
3 9 0.68 7.8e+03 -1.1 0.0 36 59 912 941 910 991 0.68
4 9 0.073 8.4e+02 2.0 0.0 36 59 1123 1152 1121 1202 0.77
5 9 0.064 7.4e+02 2.1 0.0 36 59 1334 1363 1332 1413 0.77
6 9 0.064 7.4e+02 2.1 0.0 36 59 1545 1574 1543 1624 0.77
7 9 0.073 8.4e+02 2.0 0.0 36 59 1756 1785 1754 1835 0.77
8 9 0.18 2.1e+03 0.7 0.0 36 59 1967 1996 1965 2046 0.75
9 9 0.33 3.9e+03 -0.2 0.0 36 59 2178 2207 2176 2262 0.69

Sequence Information

Coding Sequence
ATGGACAGACCTTTATCAATTGGATGGTCACGTGTTGTGACAACTGTGGAAAACTATCGAGGAAAAATTCTGGAACATGTTATAGACTATGAAGTATCATTGCAATCTTCGTTCGATTTGTTCAGCACTGAAGACACAAGTGCCATTGATATTTATAAGGCTAGAAAccaaattattaaagaaaaagatTTTACGTTCTGTGATCCAGGACCATGTTactgtaacaaaatatttacgaTTACAGTTAATCCAAAACGAAACACATTAGATATTAAACCAAGTCTGGAAGCTTTGCGTCAAATTATGATTAATTTTTCACCTATAAAACCTGAAGTACAAGCCGTAATTAGTATGATCCTCAACGCAAATTTACCAGAAGATCAATTAAgtttaagtaaaaaaattattgctttgATACATAAGCATTTGGCTTTTGATCTAGAAAATCTAGAAATTTCTGAATCTGCGGAAGTTTATGATGAAGGCAATCTGGTGAAATATGTAAATGCTAATGGAGTATATTGTTACAGAAAACTTGGAACAAATTTGCAACCAGTACCATGCCCAATGGATACATCATTAATTCCATTATACAATTTAGATTCATATAATACAGTGCCAGTAAAATATGTAGATTCTAATGGAATGGTACACTGTTTTGATATGAGCGATTATGATTTAAGACAAATAACGTGTCCTTTACATACTTCATTATTACCAGAGATTggtattaagaaatatttggaTGATAATAATAGAGAATATTGCAGTGTCATAAACGAAGTTACTTCAGTGCATTTTATTTGCCCAAAATCATTGTCTTCGCTTCCCTTGACTGTCATGGAAGACTTACAAAATGCTATAGTGAAATACGTTGATCCTCAGGGTAGACTGCGTTGTTATCTCAAAAACAATATTGCATTTAGTGAAACTGAGTGTCCcgaaaattctttaaatttgccAACTTTCAACCCATACAAAAATTTCGTCAAATATGTTGACTCCCAAGGTAGATCacattgtttctataaaaacgATGATTCATTGCAGCCTATAGTTTGTCCAGCTGATCTTTCTCAAATAAgacatatttcattaaataacgAAGCAATGCCTATAAAACATATTGGACCTGATGGCATGATACATTGCTTCACCTACGGTGCTTCCCGTTTCTACGAAAGGCAATGTCCAGATGATACTTCCTTATTCCCACTCATGTCATTACATGACTTAGACGATATTATGTTTAAGCACACAGATTTTCAAGGTAAAGTACGATGTTACAAGAAAACTGGGAATAATTACAACTTAGTAAATTGTCCTAGAGACACCTCACTAATACCAGAAGTGAGTATACTAAAACAAAACATACCTGACCTTGATTTAGTACCAGGATTTAGACCACCATTTGGAAGAGATTCTGGAATACCCCGACGAGTTCCTACCTTACCGTTGGACTCACTTTACGGACCTCTAGGAAAAGGATATTATTCAGATCAAGACCTTGTTAAATATGTGGATGCCACTGGAGAATACTGCTATAGAAAACTTGGAACAACTTTGCAACCAGTACAATGTCCAATGGATACATCATTAATACCACATCACAATCTAGATTCAGATACTGCAATTCCTGTAAAATATGTAGATTCCAATGGCAGAGTACACTGTTTCGACATGAATAATTACGACATAAGAGCAAGAATGTGTCCTTTGGATACTTCCTTATTACCAGAAATTGGTGTTAAGAAATATTTGGATGATAACAATATAGAATTTTGCAGTGTTATAAACGAAGTTACTTCAGTGCATTTTATTTGCCCAAAATCATTGTCTTCGCTTCCATTGACTTCCATGGAaaacatagaaaatattattgtcaagGCCACTGACTCGCAAGGTCGTGTGCGTTGTTACAGAAAAACAGCAAATAATTTCAGCCCAGTAAATTGTCCCAGAGACACCTCACTATTGCCAGAAGTAAATCcattaaaacaaaacatacctGACTTTGATTTAGTATCAGGATTCAGACCACCTTTTGGAAGAGATTATGGAATACCAAGACGAGTTCCTACACTACCCTTGGACTCACTTTATGGACCTTTGGGCAAAGGATATTATTCAGATCAAGACATTGTTAAATATGTGGATGCCACTGGAGAATACTGCTACAGAAAACTTGGAACAACTTTGCAGCCAGTACAATGTCCAATGGATACATCATTAATACCACATCACCATCTAGATTCAGATATTGCAATTCCAGTAAAATATGTAGATTCTAATGGCAGAGTACATTGTTTCGACATGAATAATTACGAAGTAAGAGAAAGAATGTGTCCTTTGGATACTTCATTATTACCAGAAATTGGTGTCAAGAAATATTTGGATGATAATAATGTAGAATTTTGCAGTGTCATAAACGAAGTTACTTCAGTACATTTTATTTGCCCAAAATCATTGTCTTCGCTTCCATTGACTTCCATGGAAGacatagaaaatattattgtcaagGCCACCGACTCGCAAGGTCGTGTGCGTTGTTACAGAAAAACAGCAAATAATTTCAGCCCAGTAAATTGTCCCAGAGACACCTCACTATTGCCAGAAGTGAATCcattaaaacaaaacatacctGACTTTGATTTAGGACCAGGATTCAGACCACCTTTTGGAAGAGATTATGGAATACCCCAACGAGTTCCTACCTTACCGTTGGACTCACTTTACGGACCTCTTGGCAAAGGATATTATTCAGATGAAAACCTTGTTAAATATGTGGATGCTACTGGAGAATACTGCTATAGAAAACTTGGAACAACTTTGCATCCAGTACAATGTCCAATGGATACATCATTAATACCACATCACAATCTAGATTCAGATATTGCAATTCCAGTAAAATATGTAGATTCTAATGGCAGAGTACACTGTTTCGACATGAATAATTACAATATACGAGAAAGAATGTGTCCTTTGGATACTTCCTTATTACCAGAAATTGGTGTCAAGAAATATTTGGATGATAATAATATAGAATTTTGCAGTGTCATAAACGAAGTTACTTCAGTACATTTTATTTGCCCAAAATCATTGTCTTCGCTTCCGTTGACTTCCTTGGAAGacatagaaaatattattgtcaagGCCACCGACTCGCAAGGTCGTGTACGTTGTTACagaaaaacagtaaataattTCCACCCAGTAAATTGTCCTAGAGGCACCTCACTATTTCCAGTAGTGAATCcattaaaacaaaacatacctGACTTTGATTTAGGACCAGGATTCAGACCACCATTTGGAAGAGATTATGAAATACCAAGACGAGTTCCTACCCTACCCTTGGACTCACTTTACGGACCTCTTGGCAAAGGATATTATTCAGATCAAGACCTTGTTAAATATGTGGATGCTACTGGAGAATACTGCTATAGAAAACTTGGAACAACTTTGCAGCCAGTACAATGTCCAATGGATACATCATTAATACCACATCACAATCTAGATTCAGATATTGCAATTCCAGTAAAATATGTAGATTCTAATGGCAGAGTACATTGTTTCGACATGAATAATTACGCCATAAGAGCAAGAATGTGTCCTTTGGATACTTCCTTATTACCAGAAATTGGTGTCAAGAAATATTTGGATGATAATAATGTAGAATTTTGCAGTGTCGTCAACGAAGTTACTGCTGTGCATTTTATTTGCCCAAAAACATTGTCTTCGCTTCCATTGACTCCCATGGAAGacatagaaaatattattgtcaagGCCACCGACTCGCAAGGTCGTGTACGTTGTTATAGAAAAACAGCTAATAATTTCCACCCAGTAAATTGTCCCAGAGACACCTCACTATTGCCAGAAGTGAATCcattaaaacaaaacatacctGACTTTGATTTAGTATCAGGATTCAGACCACCTTTTGGAAGAGATTATGGAATTCCAAGACGAGTTCCTACCCTACCCTTGGACTCACTTTATGGACCTTTGGGCAAAGGATATTATTCAGATCAAGACATTGTTAAATATGTGGATGCCACTGGTGAATACTGCTACAGAAAACTTGGAACAACTTTGCAGCCAGTACAATGTCCAATGGATACATCATTAATACCACATCACAATCTAGATTCAGATATTGCAATTCCAGTAAAATATGTAGATTCTAATGGCAGAGTACACTGTTTCGACATGAATAATTACGCCATAAGAGCGAGAATGTGTCCTTTGGATACTTCATTATTACCAGAAATTGGTGTCAAGAAATATTTGGATGATAATAATGTAGAATTTTGCAGTGTCGTCAACGAAATTACTGCTGTGCATTTTATTTGCCCAAAAACATTGTCTTCGCTTCCATTGACTCCCATGGAAGacatagaaaatattattgtcaagGCCACCGACTCGCAAGGTCGTGTACGTTGTTATAGAAAAACAGCTAATAATTTCCACCCAGTAAATTGTCCCAGAGACACCTCACTATTGCCAGAAGTGAATCcattaaaacaaaacatacctGACTTTGATTTAGTATCAGGATTCAGACCACCTTTTGGAAGAGATTATGGAATACCAAGACGAGTTCCTACTCTACCCTTGGACTCACTTTATGGACCTTTGGGCAAAGGATATTATTCAGATCAAGACATTGTTAAATATGTGGATGCCACTGGAGAATACTGCTACAGAAAACTTGGAACAACTTTGCAGCCAGTACAATGTCCAATGGATACATCATTAATACCACATCACAATCTAGATTCAGATATTGCAATTCCAGTAAAATATGTAGATTCTAATGGCAGAGTACACTGTTTCGACATGAATAATTACGCCATAAGAGCGAGAATGTGTCCTTTGGATACTTCCTTATTACCAGAAATTGGTGTCAAGAAATATTTGGATGATAATAATGTAGAATTTTGCAGTGTCGTCAACGAAGTTACTTCAGTACATTTTATTTGCCCAAAATCATTGTCTTCGCTTCCATTGACTTCCTTGGAAGacatagaaaatattattgtcaagGCCACCGACTCGCAAGGTCGTGTACGTTGTTACagaaaaacagtaaataattTCCACCCAGTAAATTGTCCTAGAGACACCTCACTATTGCCAGAAGTGAATCcattaaaacaaaacatacctGACTTTGATTTAGTACCAGGATTCAGACCACCTTTTGGAAAAGATTATGGAATACCCCGACGAGTTCCTACCTTACCGTTGGACTCACTTTACGGACCTCTTGGCAAAGGATATTATTCAGATCAAGACCTTGTTAAATATGTGGATGCCACTGGAGAATACTGCTACAGAAAACTTGGAACAACTTTGCAGCCAGTACAATGTCCAATGGATACATCATTAATACCACATCACAATCTAGATTCAGATATTGCAATTCCAGTAAAATATGTAGATTCTAATGGCAGAGTACACTGTTTCGACATGAATAATTACGCCATAAGAGCGAGAATGTGTCCTTTGGATACTTCCTTATTACCAGAAATTGGTGTCAAGAAATATTTGGATGATAATAATGTAGAATTTTGCAGTGTCGTCAACGAAGTTACTTCAGTACATTTTATTTGCCCAAAATCATTGTCTTCGCTTCCATTGACTTCCTTGGAAGacatagaaaatattattgtcaagGCCACCGACTCGCAAGGTCGTGTACGTTGTTACagaaaaacagtaaataattTCCACCCAGTAAATTGTCCTAGAGACACCTCACTATTTCCAGTAGTGAATCcattaaaacaaaacatacctGACTTTGATTTAGTACCAGGATTCAGACCACCTTTTGGAAAAGATTATGGAATACCCCGACGAGTTCCTACCTTACCGTTGGACTCACTTTACGGACCTCTTGGCAACGGATATTATTCAGATCAAGACCTTGTTAAATATGTGGATGCCAATGGAGAATACTGCTACAGAAAACTTGGAACAACTTTGCAGCCAGTACAATGTCCAATGGATACATCATTAATACCACATCACAATCTAGATTCCGATATTGCAATTCCAGTAAAATATGTAGATTCTAATGGCAGAGTACACTGTTTCGACATGAATAATTACGCCATAAGAGCGAGAATGTGTCCTTTGGATACTTCATTATTACCAGAAATTGGTGTCAAGAAATATTTGGATGATAATAATGTAGAATTTTGCAGTGTCATAAACGAAGTTACTTCAGTACATTTTATTTGCCCAAAATCATTGTCTTCGCTTCCATTGACTTCCATGGAAGacatagaaaatattattgtcaagGCCACTGACTCACAAGGTCGTGTACGTTGTTACagaaaaacagtaaataattTCCACCCTGTAAATTGTCCTAGAGACACCTCACTATTGCCAGAAGTGAATCcattaaaacaaaacatacctGACTTTGATTTAGGACCAGGATTCAGACCACCTTTTGGAAGAGATTATGGAATACCCCGACGAGTTCCTACCTTACCGTTGGACTCACTTTACGGACCTCTTGGCAACGGATATTATTCAGATCAAGACCTTGTTAAATATGTGGATGCCACTGGAGAATACTGCTACAGAAAACTTGGAACAACTTTGCAGCCAGTACAATGTCCAATGGATACATCATTAATACCACATCACAATCTAGATTCAGATATTGCAATTCCAGTAAAATATGTAGATTCTAATGGCAGAGTACATTGTTTCGACATGAATAATTACGATTTAAGACCACGAAACTGTCCTTTGGATACTTCATTATTACCAGAAAtcaatgttaaaaaatatttggatgATAACAATAGAGAACATTGCAGTGTTTTCAATGGAGTTAGTACAATACAATTTGCTTGTCCACGATCGTTGTCTTCGCATCCATTGACACCCTTGGATGCCATAGAAGATATTGTTGTAAAGAACACCGATATGCATGGCCGAGTTCGTTGTTACAGAAAAACAGCAACTAATTTCAATTCAGTTATTTGTCCCAGAGATACCTCAATGCTACCAGAAATAAATCCatttaaaaatcttaattttgGACCAGAATTTAGGCCTCCATCTTTTGGAAGAGATCGTGGAATATCAAGACCAGCTTTTGGAATGAATACTAAGTTAGGAACATCAATAGAAGACGTTCAAAATGGACCAATTAGATACAGAGATCCTCAAGGTTTCGGATTTGGAAGAAATCCGCTTATGGACATTATAACTGGATTGAATATAGGAAAAGGTTCGGGTAATTTCTCTCCGGGTGGTTCTGGAGAAATACAAGTTACTTACAATGATTTAATGACATTAATTAAACATATGTGTAAAAaggtttaa
Protein Sequence
MDRPLSIGWSRVVTTVENYRGKILEHVIDYEVSLQSSFDLFSTEDTSAIDIYKARNQIIKEKDFTFCDPGPCYCNKIFTITVNPKRNTLDIKPSLEALRQIMINFSPIKPEVQAVISMILNANLPEDQLSLSKKIIALIHKHLAFDLENLEISESAEVYDEGNLVKYVNANGVYCYRKLGTNLQPVPCPMDTSLIPLYNLDSYNTVPVKYVDSNGMVHCFDMSDYDLRQITCPLHTSLLPEIGIKKYLDDNNREYCSVINEVTSVHFICPKSLSSLPLTVMEDLQNAIVKYVDPQGRLRCYLKNNIAFSETECPENSLNLPTFNPYKNFVKYVDSQGRSHCFYKNDDSLQPIVCPADLSQIRHISLNNEAMPIKHIGPDGMIHCFTYGASRFYERQCPDDTSLFPLMSLHDLDDIMFKHTDFQGKVRCYKKTGNNYNLVNCPRDTSLIPEVSILKQNIPDLDLVPGFRPPFGRDSGIPRRVPTLPLDSLYGPLGKGYYSDQDLVKYVDATGEYCYRKLGTTLQPVQCPMDTSLIPHHNLDSDTAIPVKYVDSNGRVHCFDMNNYDIRARMCPLDTSLLPEIGVKKYLDDNNIEFCSVINEVTSVHFICPKSLSSLPLTSMENIENIIVKATDSQGRVRCYRKTANNFSPVNCPRDTSLLPEVNPLKQNIPDFDLVSGFRPPFGRDYGIPRRVPTLPLDSLYGPLGKGYYSDQDIVKYVDATGEYCYRKLGTTLQPVQCPMDTSLIPHHHLDSDIAIPVKYVDSNGRVHCFDMNNYEVRERMCPLDTSLLPEIGVKKYLDDNNVEFCSVINEVTSVHFICPKSLSSLPLTSMEDIENIIVKATDSQGRVRCYRKTANNFSPVNCPRDTSLLPEVNPLKQNIPDFDLGPGFRPPFGRDYGIPQRVPTLPLDSLYGPLGKGYYSDENLVKYVDATGEYCYRKLGTTLHPVQCPMDTSLIPHHNLDSDIAIPVKYVDSNGRVHCFDMNNYNIRERMCPLDTSLLPEIGVKKYLDDNNIEFCSVINEVTSVHFICPKSLSSLPLTSLEDIENIIVKATDSQGRVRCYRKTVNNFHPVNCPRGTSLFPVVNPLKQNIPDFDLGPGFRPPFGRDYEIPRRVPTLPLDSLYGPLGKGYYSDQDLVKYVDATGEYCYRKLGTTLQPVQCPMDTSLIPHHNLDSDIAIPVKYVDSNGRVHCFDMNNYAIRARMCPLDTSLLPEIGVKKYLDDNNVEFCSVVNEVTAVHFICPKTLSSLPLTPMEDIENIIVKATDSQGRVRCYRKTANNFHPVNCPRDTSLLPEVNPLKQNIPDFDLVSGFRPPFGRDYGIPRRVPTLPLDSLYGPLGKGYYSDQDIVKYVDATGEYCYRKLGTTLQPVQCPMDTSLIPHHNLDSDIAIPVKYVDSNGRVHCFDMNNYAIRARMCPLDTSLLPEIGVKKYLDDNNVEFCSVVNEITAVHFICPKTLSSLPLTPMEDIENIIVKATDSQGRVRCYRKTANNFHPVNCPRDTSLLPEVNPLKQNIPDFDLVSGFRPPFGRDYGIPRRVPTLPLDSLYGPLGKGYYSDQDIVKYVDATGEYCYRKLGTTLQPVQCPMDTSLIPHHNLDSDIAIPVKYVDSNGRVHCFDMNNYAIRARMCPLDTSLLPEIGVKKYLDDNNVEFCSVVNEVTSVHFICPKSLSSLPLTSLEDIENIIVKATDSQGRVRCYRKTVNNFHPVNCPRDTSLLPEVNPLKQNIPDFDLVPGFRPPFGKDYGIPRRVPTLPLDSLYGPLGKGYYSDQDLVKYVDATGEYCYRKLGTTLQPVQCPMDTSLIPHHNLDSDIAIPVKYVDSNGRVHCFDMNNYAIRARMCPLDTSLLPEIGVKKYLDDNNVEFCSVVNEVTSVHFICPKSLSSLPLTSLEDIENIIVKATDSQGRVRCYRKTVNNFHPVNCPRDTSLFPVVNPLKQNIPDFDLVPGFRPPFGKDYGIPRRVPTLPLDSLYGPLGNGYYSDQDLVKYVDANGEYCYRKLGTTLQPVQCPMDTSLIPHHNLDSDIAIPVKYVDSNGRVHCFDMNNYAIRARMCPLDTSLLPEIGVKKYLDDNNVEFCSVINEVTSVHFICPKSLSSLPLTSMEDIENIIVKATDSQGRVRCYRKTVNNFHPVNCPRDTSLLPEVNPLKQNIPDFDLGPGFRPPFGRDYGIPRRVPTLPLDSLYGPLGNGYYSDQDLVKYVDATGEYCYRKLGTTLQPVQCPMDTSLIPHHNLDSDIAIPVKYVDSNGRVHCFDMNNYDLRPRNCPLDTSLLPEINVKKYLDDNNREHCSVFNGVSTIQFACPRSLSSHPLTPLDAIEDIVVKNTDMHGRVRCYRKTATNFNSVICPRDTSMLPEINPFKNLNFGPEFRPPSFGRDRGISRPAFGMNTKLGTSIEDVQNGPIRYRDPQGFGFGRNPLMDIITGLNIGKGSGNFSPGGSGEIQVTYNDLMTLIKHMCKKV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-