Hsub013642.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Harpagoxenus sublaevis
Gene Symbol
Baz2b
Assembly
GCA_030770355.1
Location
JASTWR010000089.1:206347-230355[+]

Transcription Factor Domain

TF Family
MBD
Domain
MBD domain
PFAM
PF01429
TF Group
Unclassified Structure
Description
The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 1.2e-21 8e-18 65.2 0.0 4 76 559 631 556 632 0.93

Sequence Information

Coding Sequence
ATGCCGGGTGGTTATGGCCTGGGGGCCCCCCATTTGCCCTCGGCTTACGCTATTCTGGGCCGGGGGAGCTCAGCGCCTGGCTTCGGGGGCCACACACCAGCCTCGGCGCCACCCCCGTCCCCGTACCCTCACAGCAGCCTCGGTACACTCAGCGTGGCCGCCAGTCAAGCTGCGAGTCTGGGCATCAATCCAGCAGCAAGTGCATGGTGGACAATGGCCTCTCATCTGGCGGCGCAAGACTACCTCGCGAGGCTACAAGGAGCGGCAGGACTCCCAGGATTTCCGCCCGGTGCCGAGAGCCTCCTGCCACCCTATCCCGCCTCTCTACTTAATCCCCCGTCCCTCTCGTCTCACAAGTCCAGTAAGTCTAAGTCAAGCAAGAGTCACAAGACACCAGCTAGCAGTAGTAGCTCAACGACGCCAAGTATGACGAGCAGCAGCATGCCGGTGTCCACTCAACCACCGGTGACGTCTCATCACAGCACTCCGGTTAGCAGCACGCCAAATTCGCAATCGAACGTCGTCAGTGATCCTAGCAGTATATTGGGAGGTGTGCGCCTACCTCCCGACACGGAGATTATCAAGTATACGTCGAGTATAGTCGGTCCGAAGGTTCCTGGGACGACGAACCGCGGCAGGAAGAAGACAATATCCCTGGACTCTCCCAGCGTCAGCGTACACCCGCCGCCCGTCGCTGCCCTTAGCGCCCATCAGTTGAACACGACGTCATCCGCGTCGCTAATGATGGAACCGAGGAAGTATAATCGCACCGGGACCGACTCGAACGAGTACAGAGATTCGGTGGATCGAGTAGAGGTAATCAAACTGCCGGCCCATTCAACGAACGGCTCCGTTCTGTCGGCGCCACCGACGTATACTAGCAGCAGTAGCAGCGGTAACAGCAATGCGAACAACAATATCAACGATTCGGACGCACCCCTAAATCTCTCCCTGAAGCCCGCCACGACGAGCAGTAGTTCGCCGATTTCTGGTAGTCAGCCGCTCAGTCAGCTCAGTAATTTAAGCCAATCGTTACTTGCCTCCGATCGAACGTCGAGACGGAAGCCTGGACCGAAGCCGAGAAGAGTGCCGCAGAATTCGGTGCCGGTGCCGGCGTCGCCTAGTCCCTCTTTGGCGCAGCTTTTCGCCGCCGCGGACTCGCCACAGCGGCCGAGTAGCGGCAGCGAGGAGAGCGAGAGTGCGAGCACTGCCACCCATCACAAGGACGGTAGGCCGCGAAATCTCGGCCGCGGTGTATCGAAGCCTAAGAAGAACACCGTCGCGTCATTGCTGGCTCAAAGCAGAGCTCTAGGAATTAAGCCCACTCCGACTTTGGATCCAAGTGTGCCATTGTCTCACCAAGTATCGTTGCTGAGATCTAATATACTGGCGGCTCAATTGCACGCTTCCGTCGCTACTGGCCAGGGCGACGATAAGAACCAGTACTATCACTTGCTAACGAAGATACAGAAGAAGAAGCGACCTCGACCAATTCGTGCTTCGTGGGCGAGGAGCCATGAAAAGATGAAAAACAAGTTACTGGAGGCCTCGGGAGAAGAGAGTAACATGGACGTGACCAGCGAGAGCGGCAGTAACACCGACGTTGTCACGGATACCGATGACGACAATACGGAAGGCACACCCAGCGCGAAGAGGAGAAAGCTCAAGCCCAGCGAAAGAGACCTTCAAATGCCGTTAGAGCGCGGTTGGAAGCGTGAAACGGTTATCAAGGGACTAGGAAAGACGGGAGTGATAAAAGGCGACGTGTCGTATTACAGCCCCTGCGGGAAAACTTTTAGGAGCAGTCCCGATCTGGTGAAGTTTCTGGAGCATCAGAATCCAGCTGAGCTAACAACCGCCAATTTTTCGTTCTCCTCCCGCCCGTTGGTCGGCGAATTCCTGCAGCCAACGATGGGTCTAGCGGAAGCTGAATTCGTCAGACTCGGTGCTCAGGAAGTAGCGCGAAGATTGGAAGAGCTCAGAGCGGTTGGTGGTTTCAGAGACGCACGGCCGAACAATCAGTACGAGAGAGACAAGCTGGCTTACGCGAAGAAACTTGCGAAGGAAGAAGCGCAACGGCACAAAGAACAAGCTAGGCTTATTAAGGAGCAAGAGAAGACGGAACGGCAGGAAACCTTGAGACGAGAACGGGAGATCAGGAATCAACAGCTACTCGAGGGTCGAAAGCGGCTCGCGTTCACGATCAAGCAGAAAATGAAGATCATCCAAGAGATCGAGCGCGGCAAGAGCAAGAGCGACGTGGCTCGCGAGCTGGGTCTGGCGAGCAGTACGGTCGCCACCATCTGGAAGAATCGCGAGAGCATCGCCGAGAGCTGGCGCAACCGGGACATGATGCACCAGGCGGACGTCGAGGACGTGCCGTCGAAGAAGCCGCCGTCGATGTCGTCCCTCGCGTCGACCACGGCCGCGCTCTGCACCCCGGTAGCGATGacaacgatgacgacgacgactgCGATCACGACGACACCGCCGTCTCTGGCCACCGGGGTGGTCGTGCCGCCTCCGCAGGTGCAGGTGGTGCCGCCGGTCCTGCCGCCGCCACCCTATCCCACCCTGACCCTGCCGCCGGCGTCGGCGGGCCTTGTGCCGTCACCGCAGCCGACGGCGCCGATCTCCTCCTCGTCGAACCTGTCATCGACCACCACGTCGACCGGCACGACGACCGCGACCATGCCGTCGGACAATACCCAGCAGGCACAGACCCAGACGCAGAGCCAGGAACTTCTGGAGGCACGGAAAAAACGGGAGGAAGAGGTGCAGAAGATCCGACTGGAAGAACAACAAAGGAAGCAACAGGAACGAGAGCTGAAGCGGCAGCAGGCGGTCATGCTGAAAGAGCAGATGTACATGCAGGAGCTCACCAAGCAGCGCGAGATGCTCTACACCGTCGAGCTGgagagggagagaaggaggcaGCATATGACTCTGGTACGGGCACTGGAGAATCGCCGGAAGAtggaggagaaagagaagaaacgCCTGGAGGCCAGGGCCGAGAGGATAGCGACGAAGGAAAAGCGGGCGGAACAGAGGAGAGTCGAGATGGAGTTGATCGAACAAATTCGCAAGCCCGTAGAGGATATGGAGCTGACAGATCACAGACCACTGCCAGAAGTTAAAAGAATACCTGGACTTAAGCTCTCCGGGCAGGCGTTCGCAGACATCGTCATGGTCTTCGAATTTTTACACAATTTCGGGGAGACTTTAGGATTCGATATGGAATCGTTACCGAGCTTGAAGAGTCTTCAACTCGCTCTTCTCAATGACGAAGAAGCCGAAGAGGAGATGCTGTCGGTTATGACGCATCTGTTGGTGTGTGCCATTGAAGATCCAGGAATCCCGCAACCGGCTAGACACACCACAGGCCTGGGTCAGAGTTTGCGTCAAGCTGACATCACTCACGCCAACATCAGTGAAGTATTGCGAATTTATTTGTACGCGAACGCAACCGGCGAGGTAAAAGCTCTGACAGGGGTGTGCCTTGAGCGTGAGCGCGACAAGAAATTTGCCGATCATCATCAGAACGGCGGCGATTACGCTTCGACTTGCTCGGGGAAGAACGCGCAGTTCTATGAGCATTTACATAACAACGAAACGTGGAAGATGTCGGAAAGATTGCGAGACAAGCCTTTCCTAGCGTTGAATTCAACGCATAAGGCGCAGATGCTCGCTTTCCTTTGCAACGAGCTGCTGCAAAATAAGGCTGTGATCAGACAGATAGAGGGTAGCCTCGAGACGGTGGCTCAGTTGAGGAAGGAGAGATTCGTATTGGATACCAAAATCAGAAAGCTTAGACAATTGCATAGTCGAAAAGTCCGAATGGAAGCTGTAGGCGTCATTGTGAACAAGATTGGTGACACAATCACCATCGAGAAGAAAGAAGGTGAGGAAGAAGGTAATACTACTTCCACTGCCGTAGGTACGACACCTACACCGGACGAGATTCATCATGAGGACGAAGTAGAAGACATGTCGGAGAATGAGAGTGAAGGCACTCAGCCAGAAGAGGAGGAGGATAAAAATTTGTCTGGCGAAGAATTGGGTAAAAAATTGGATAAACTATTGAAGCAATCAGAGGAACAACTGCAAAAGCTGAACAGCTCTTCGAAGCAACTCCGTGCGCATATATTCGGCCAGGACAGGTATTGGAGGAGATATTGGGAATTAGCATGCGCCGGCGGCATCTTCGTGGAAGCCATGGAGAGCGCCGAACCGGAGGTTCTCGAACTCCAAGCCGAGCTCGACGAGAAGTACAAAAATATGCCGGTGGAGGAGAAGTCCGATGTGAAGCAAGAGAGCGAAGGCAAGACAAATTCCGAAAATCGTGAAAATGAGGCGCCGAACGAAGTCAAAGATGAAAAGAAACACAACTTGTGTGAGCAAGATGAGGACATGAAATCTCATGGGGATAAGCTGAAGTATGAGGTGGAGGAGGTCAACTGTAAGAAAGAGTCTGTACAAAAATGCAGCTCGGAAAATTCCGAGGGTGTAAAGGAGAAGAGAAACAATGACGTTGATAGTACAATGACAGATGCGAAGACGAATGTCACGTCCGAGGAAATAAAACAGGAGACGGAGGTGATGGATGTCGATATGAAAGAGGAAGTGAAAAAGGAGAACGAGGAAACGGATGAAGATATGACGAAACCTCTGGTGAAAACGATGGAGGACAAGATTGTGGAAACGATACCGAATGGCGACAAGTTCAACCACGTCAATAATCTGCACAACGGGAAGGAACTCAACGGCTCCTTTATTTCTATTATGTCGATTATTTCAGATAACAGCAATGCCGAGCCTAATTGGTTTTCCATCTTACCGCGTGAAACGTGCGATACTCCGGGAGCTAGCACTAAGCAAATCTTTGGCATAGCCGAGCCGACCGAGCTTAGAATCCCAATATTCCCACCGCCAGCTAGTCCGAGTTACGATAGATGCGACAGTCCAGCGCCCTTGATATTAACTCAAGATGAGGCAGCACAATTAGAATATTTGAAAGTGCACGGTTTGCCGCCTCCTGGCGAAGCCAAACCGGTGCCGAAAGATTTGAGATACGGTTGGTGGAGGATAACAGATGTCGACACGTTCCAAGAGCTTCTCGAGCATCTACATTCTCGCGGCGTCCGCGAGAAAGAATTGAAGCGCACAACGTGGGCGACAATGGAGTCCTTCTTAGCTGTAACCGGTAAAATTAATGTTGATCCTGGCAACATGTCCGCCACGGAACTTCAAGCAGAACCAGACGATCCCAACACGCCAATTCCGAAGCCTGATAATCCGAGCAACTGGAGCGAGCAAGTTGCGCTACGAGTAGATGCTCAACTCTTGGAGCAAGTGGAAGCGCTTGAAGATAAAGTAGCTAACGCTAGCATGCAAGTCAAAGGCTGGAAACTACCGCCGCGAGCGGGAACTGAGGAAGCCGAAGAAATTGATAAGTTGAACGAAATGGAGAAGATTAGCGCGGTCGAGCAAGCGCGGCAAAGGCTACTTTCTTTGGAGGCAGCTATAGAAAGGAGATACTTGAAACCACCTTTAGGCGTTTGcACGGGAGATCCCAATTTAGCAGCCCTCAAGGCGGAACAGGCGGCGGCCGCTAACGCAAACTCGAATAATTCCGAGCAGAATAACCAGGCGCCTGCACCGCCAGAGGAAACGACGCCGCGCGGTCTGAACACCTGGCGGGAGGCGACGGCACGAGCGCACACGTCGGCGCAACTCGCTATGGCGCTCTACATGCTCGAGGCCAGCATCGCTTGGGACAAGAGCATCATGAAGGCTGTGAGTCTAACAACAGCTAGAAACTCGGTCTGCGCCAAACTACGAAACCGCTGCGTCTCACTCAAAGCTACCAAACAGTACAAACAGCTATTGACTACTTCTCAGACCTCTAATTGCCAGTTTTGTCATAGTGGAGACAACGAAGATAAGCTGCTACTCTGTGATGGCTGTGACCGTGGCTACCATACTTACTGTTTCCGTCCAAAAATGGAAAACATTCCTGATGGTGACTGGTATTGTCACGAATGTATGAACAAAGCAACAGGTGAACGCAATTGTTTAGTGTGTGGAAAGAGAGCGGGTAAAAACCTGGTCCTATGCGAACTCTGCCCTAGGGCTTATCACACTGACTGCCATAATCCTGTCATGCCAAAAATGCCACGAGGAAAATGGTATTGCTCTAATTGCCACAGTAAACAACCAAAGAAGAGAAATAGTAGTCGAAGGAGTCATACCAAAGGGGGAGGCACCAGAGAAAGTGAAAGTTCTGACCATCCACCAGCTAGTCCAACGCCATCAACGGCATCGAACACGCACGTAGAGGATGTCAGTTCGTCGGAACCGCCGACTCCTACCGCCTCACCACGGAAGGAGGGTAACAATCGGACGCTCACGAAGAAGCAACAACGAGAGCTGGCGCCTTGTAAGATACTCCTCGAACAGTTGGAGCAGCAGGACGAGGCCTGGCCGTTCCTCCTGCCGGTGAACACCAAACAGTTCCCGACCTACAAGAAAATCATTAAAACCCCCATGGATCTCAGTACGATTAAGAAGAAATTGCAGGACTCCGCGTACAAGTCTCGCGATGAGTTTTGCGCCGATGTCAGGCAGATGTTCATCAACTGCGAGGTATTCAACGAGGACGACAGTCCTGTGGGCAAGGCTGGCCATGGGATGCGCAGTTTCTTCGAAATGCGCTGGACCGAGATCACCGGCGCACCGCCTCCGCATCCGCAAACGCATAGCTGA
Protein Sequence
MPGGYGLGAPHLPSAYAILGRGSSAPGFGGHTPASAPPPSPYPHSSLGTLSVAASQAASLGINPAASAWWTMASHLAAQDYLARLQGAAGLPGFPPGAESLLPPYPASLLNPPSLSSHKSSKSKSSKSHKTPASSSSSTTPSMTSSSMPVSTQPPVTSHHSTPVSSTPNSQSNVVSDPSSILGGVRLPPDTEIIKYTSSIVGPKVPGTTNRGRKKTISLDSPSVSVHPPPVAALSAHQLNTTSSASLMMEPRKYNRTGTDSNEYRDSVDRVEVIKLPAHSTNGSVLSAPPTYTSSSSSGNSNANNNINDSDAPLNLSLKPATTSSSSPISGSQPLSQLSNLSQSLLASDRTSRRKPGPKPRRVPQNSVPVPASPSPSLAQLFAAADSPQRPSSGSEESESASTATHHKDGRPRNLGRGVSKPKKNTVASLLAQSRALGIKPTPTLDPSVPLSHQVSLLRSNILAAQLHASVATGQGDDKNQYYHLLTKIQKKKRPRPIRASWARSHEKMKNKLLEASGEESNMDVTSESGSNTDVVTDTDDDNTEGTPSAKRRKLKPSERDLQMPLERGWKRETVIKGLGKTGVIKGDVSYYSPCGKTFRSSPDLVKFLEHQNPAELTTANFSFSSRPLVGEFLQPTMGLAEAEFVRLGAQEVARRLEELRAVGGFRDARPNNQYERDKLAYAKKLAKEEAQRHKEQARLIKEQEKTERQETLRREREIRNQQLLEGRKRLAFTIKQKMKIIQEIERGKSKSDVARELGLASSTVATIWKNRESIAESWRNRDMMHQADVEDVPSKKPPSMSSLASTTAALCTPVAMTTMTTTTAITTTPPSLATGVVVPPPQVQVVPPVLPPPPYPTLTLPPASAGLVPSPQPTAPISSSSNLSSTTTSTGTTTATMPSDNTQQAQTQTQSQELLEARKKREEEVQKIRLEEQQRKQQERELKRQQAVMLKEQMYMQELTKQREMLYTVELERERRRQHMTLVRALENRRKMEEKEKKRLEARAERIATKEKRAEQRRVEMELIEQIRKPVEDMELTDHRPLPEVKRIPGLKLSGQAFADIVMVFEFLHNFGETLGFDMESLPSLKSLQLALLNDEEAEEEMLSVMTHLLVCAIEDPGIPQPARHTTGLGQSLRQADITHANISEVLRIYLYANATGEVKALTGVCLERERDKKFADHHQNGGDYASTCSGKNAQFYEHLHNNETWKMSERLRDKPFLALNSTHKAQMLAFLCNELLQNKAVIRQIEGSLETVAQLRKERFVLDTKIRKLRQLHSRKVRMEAVGVIVNKIGDTITIEKKEGEEEGNTTSTAVGTTPTPDEIHHEDEVEDMSENESEGTQPEEEEDKNLSGEELGKKLDKLLKQSEEQLQKLNSSSKQLRAHIFGQDRYWRRYWELACAGGIFVEAMESAEPEVLELQAELDEKYKNMPVEEKSDVKQESEGKTNSENRENEAPNEVKDEKKHNLCEQDEDMKSHGDKLKYEVEEVNCKKESVQKCSSENSEGVKEKRNNDVDSTMTDAKTNVTSEEIKQETEVMDVDMKEEVKKENEETDEDMTKPLVKTMEDKIVETIPNGDKFNHVNNLHNGKELNGSFISIMSIISDNSNAEPNWFSILPRETCDTPGASTKQIFGIAEPTELRIPIFPPPASPSYDRCDSPAPLILTQDEAAQLEYLKVHGLPPPGEAKPVPKDLRYGWWRITDVDTFQELLEHLHSRGVREKELKRTTWATMESFLAVTGKINVDPGNMSATELQAEPDDPNTPIPKPDNPSNWSEQVALRVDAQLLEQVEALEDKVANASMQVKGWKLPPRAGTEEAEEIDKLNEMEKISAVEQARQRLLSLEAAIERRYLKPPLGVCTGDPNLAALKAEQAAAANANSNNSEQNNQAPAPPEETTPRGLNTWREATARAHTSAQLAMALYMLEASIAWDKSIMKAVSLTTARNSVCAKLRNRCVSLKATKQYKQLLTTSQTSNCQFCHSGDNEDKLLLCDGCDRGYHTYCFRPKMENIPDGDWYCHECMNKATGERNCLVCGKRAGKNLVLCELCPRAYHTDCHNPVMPKMPRGKWYCSNCHSKQPKKRNSSRRSHTKGGGTRESESSDHPPASPTPSTASNTHVEDVSSSEPPTPTASPRKEGNNRTLTKKQQRELAPCKILLEQLEQQDEAWPFLLPVNTKQFPTYKKIIKTPMDLSTIKKKLQDSAYKSRDEFCADVRQMFINCEVFNEDDSPVGKAGHGMRSFFEMRWTEITGAPPPHPQTHS