Hqua002925.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Halictus quadricinctus
Gene Symbol
egg
Assembly
GCA_028454245.1
Location
CM052119.1:9464070-9469056[-]

Transcription Factor Domain

TF Family
MBD
Domain
MBD domain
PFAM
PF01429
TF Group
Unclassified Structure
Description
The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 7.5e-14 2.9e-10 39.7 0.1 5 70 619 678 616 684 0.88

Sequence Information

Coding Sequence
ATGGAGGTAATTGAGCTTGTCTCGGATGAAGAAGCTGCAGAAGACAATACAAAGGAAAACAAGAGTTCTAAAATTTACAATAGCAATTGCATAAATTTTCAATGTTTGTCCGGGATAGACATGAGATCAGCTCCTTCGTTTGCATGCGCCTACTATGGTGCAAATACAGAGAAGAAGAAGAAACGTATGATATGTAAGAAATGTTTTAACGCTGCATTAGACCATCAGAAGCAATTAGTCGCAGCTTTCGTGGATCGTAAACCACTGTTGAAATGTGAATTTCCGGATCACACAATGGAGGTAGAAATATCTGATAGCGATGAATCGGATGATGAAAAAAAGAAAGACATAAGTGATGAAGAGAAATATTTGCCAGAGGAACTACTTAAGGGTATCGAGGAAATGTTAGAAGGTACTTTAAAAAATGTTTATACCAAATACGATGTTGATTATCAAATCAAGGAATCTCATGATATACTAAAAGAGCAGTGGGATAAAATAAATGAAAACACAGAAGTTTTGAACAAAACAGTTGGAGATTTAATGCGTACTATGGACACGTTACGTAACAATTTATACAATGACTTCAGACCACAAATTCAAATGTTACAAGAGCTTCAAATAGAAGATGGAATTTCGGATAATACTTTGTATCCATTGGTAGCAACAAAAAAAGTTACGCAAGTACGAGTGTCAGCTGCAATGCTACAACAAGATAGTCAACCAGAGATATTACCTATTGATCAAGACAATAAGCAAGTCTTAGCTTTGGATTTACCTCCACCTGGTCCACTTGTGAAACCGCAAATAGATGTGGACAATGTTGTGTATATTATGAAGCATCCACTTATGCCATGGATTAAAGCAAAGGTGCAAACTGTTGTTTCAAAAGCTCCATTGCATTGTCGTGTGAAGTTATTGCAAAAGAAGTACAATTCGATTGTGAAATCTGTTTTTGGCAAACAAGTTGCACCCGCCGTAACTAGTCCAGTAATAATTCCAGTTGGAACAAGAGTAGTTGCAGTCTTTCGGGATGTTGCATCTAGTAACTTTTACAGTGGTGTGATAGCCGAAACACCAAAAGCTACAAACAAATACAGGTATTTGATATTCTTTGATGATGGATATGCTCAGTATGTTGAGCACAGGCATATTTATTTAGTTGCTGAATCCTCTGCCAAGGTGTGGGAAGATATACCTCACGAGTCTCGAGATTTTGTGAAAAAATACATTGAGACGTATCCTGAAAGGCCAATGGTAAAATTACAAACGGGGCAAGTAGTGAAAACAGAATGGAATGGCAAATGGTGGATTGCCAGGGTAGTACAAGTTGATGCAAGTTTAGTGCAAATGCATTTTGATGCTGACGGAAGAACTGAGTGGATTTACAGAGGATCTGCTAGATTAGGGCCGTTATATCTCGAACTCTTGAAAGCTAATGCCAGGCAACAAGGGCATCATGCTTCTGTTAATACCCCAACTCGGCATAGACTTCCTGCTGTTAATaatAAAAACAATTTACCTTATGTAGAATATACATCTAATATAGAACCTGAAGAAGATAGAATTATTCAAACAGAAAAAGCACAAAGTCCTGTAGTCAGTGAAAGTACAACTGCGGTTACCCCTACTGCACCACAGCAGGCGCGAGCTGTTGCCAGGAAGAGTACCGCTAAAAAACAAACTGTCGTTGATACAAATACCTATACTCCTAGCACTGAAACAAAACCTTCGCATAGCATAGTTTATTATCAAACGCAAAATAAGATTCAAACAAAGAAATTTGTTCCACACAAGTGTGGTCCACAATGCGTTCAGGGTATATCCTTCACACCTGACGATTTGAGAGGCTATTCGCCACTTTCAATACCGCTGCTCTGCGGTTGGAATCGACAACTTTGTAAATATCCTAAAGGCAAAAAGATCACGTTATATCAAGCTCCCTGTGGCGTCAGATTACGGAATATGGAAGAGTTACATCAGTACCTTCGCAAAACGGGTAGTCCAATGTCTGTTGATCTATTTGATTTTGACTATTGGGTACACTGTCTAGCCGAGTTTGTTTTAGATAAATGTTTCATTAATATAAAAGATCTCAGTTATGGAGTAGAAAACGTACCAATACCATGTGTCAATGAACTAGACCACACCCAACCAGATACTATTCGTTATAGTACTCTAAGGGAACCCACGGAAGGTGTCAATCTTAACTTAGATCCAAAATTCCTATGCAGTTGTGATTGCGAAGATGATTGTCAAGATAAGACGAAGTGTCAGTGCTGGCAACTAACAATACAAGGTGCAACTCTTGGAGGAAGAGTGCCAAACACATCTGTTGGTTATGTGTACAAACGTCTACCAGAACCAGTGACTACTGGAATCTACGAATGTAATTCAGGATGTAAATGCGCTGTAAAGACTTGTTTGAATAGGGTAGTGCAACATCCTCTAACATTGAAATTACAAGTGTTCAAAACAGCTCCCCGAGGTTGGGGCATTAGATGCCTAAATGATATTCCTCTGGGATCTTTTATTTGTATTTATGCTGGCAGATTGCTTACGGAACAGGGAGCTAATGAAGGTGGAAAAAATTATGGTGACGAATATTTAGCTGAATTGGATTACGTTGAAGTAGTGGAAGGAATTAAAGAAGGCTACGAGAGTGACGTTCTTGAGCCAGAGATGCCAATATCTACACCAGATGATAAAAAGAAGTCTGTGACAAGCGACGATGAAGATTATACGAGACCAAATACGAACGATTCGGATGAGGACTTCGACATTAGCAAGTATGCAAACTTCAATGTAGATTCATCAGATCCTTCATCTATCAGAAAACGACTTAGAAAACGAAAGCGAGAAGAGACCAATAATCAGGATGGGTCAGAAGAGAACAGCGAAGATGGAATTAGTACAAAAAATTCTGAAATTCTATCAAAATCATCAGCGAGTGAAAATCAGGAGGCAATCACAATAAGCGATGAAGAAGAAAATAGAAGCGGTAGACGTGAACCAAGTAGATTTGACCCTACGGTGGAGCCAGCGCAATTAGAGAGGCCTACATTTAAGTCAGTGAGAGATTTCTTTGGAGAGGAAGAGGCTGTTTATATAATGGATGCCAAAACAACGGGAAATATAGGACGTTATTTAAATcactcttgcgatccaaacgttttcgttcaaaacgtatttgttgatacacacgatgtaagatttccaggtcgactTTTATAA
Protein Sequence
MEVIELVSDEEAAEDNTKENKSSKIYNSNCINFQCLSGIDMRSAPSFACAYYGANTEKKKKRMICKKCFNAALDHQKQLVAAFVDRKPLLKCEFPDHTMEVEISDSDESDDEKKKDISDEEKYLPEELLKGIEEMLEGTLKNVYTKYDVDYQIKESHDILKEQWDKINENTEVLNKTVGDLMRTMDTLRNNLYNDFRPQIQMLQELQIEDGISDNTLYPLVATKKVTQVRVSAAMLQQDSQPEILPIDQDNKQVLALDLPPPGPLVKPQIDVDNVVYIMKHPLMPWIKAKVQTVVSKAPLHCRVKLLQKKYNSIVKSVFGKQVAPAVTSPVIIPVGTRVVAVFRDVASSNFYSGVIAETPKATNKYRYLIFFDDGYAQYVEHRHIYLVAESSAKVWEDIPHESRDFVKKYIETYPERPMVKLQTGQVVKTEWNGKWWIARVVQVDASLVQMHFDADGRTEWIYRGSARLGPLYLELLKANARQQGHHASVNTPTRHRLPAVNNKNNLPYVEYTSNIEPEEDRIIQTEKAQSPVVSESTTAVTPTAPQQARAVARKSTAKKQTVVDTNTYTPSTETKPSHSIVYYQTQNKIQTKKFVPHKCGPQCVQGISFTPDDLRGYSPLSIPLLCGWNRQLCKYPKGKKITLYQAPCGVRLRNMEELHQYLRKTGSPMSVDLFDFDYWVHCLAEFVLDKCFINIKDLSYGVENVPIPCVNELDHTQPDTIRYSTLREPTEGVNLNLDPKFLCSCDCEDDCQDKTKCQCWQLTIQGATLGGRVPNTSVGYVYKRLPEPVTTGIYECNSGCKCAVKTCLNRVVQHPLTLKLQVFKTAPRGWGIRCLNDIPLGSFICIYAGRLLTEQGANEGGKNYGDEYLAELDYVEVVEGIKEGYESDVLEPEMPISTPDDKKKSVTSDDEDYTRPNTNDSDEDFDISKYANFNVDSSDPSSIRKRLRKRKREETNNQDGSEENSEDGISTKNSEILSKSSASENQEAITISDEEENRSGRREPSRFDPTVEPAQLERPTFKSVRDFFGEEEAVYIMDAKTTGNIGRYLNHSCDPNVFVQNVFVDTHDVRFPGRLL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00684169;
90% Identity
iTF_00763230; iTF_00862565; iTF_00863272; iTF_00860393; iTF_00865321; iTF_00861142; iTF_00864639; iTF_00863955; iTF_00861877; iTF_00024620; iTF_01071024; iTF_00966031; iTF_00183949; iTF_00183287; iTF_00866010; iTF_00866704;
80% Identity
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