Hpyr011588.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Habrosyne pyritoides
Gene Symbol
Rfx2
Assembly
GCA_907165245.1
Location
OU015589.1:13293852-13314514[+]

Transcription Factor Domain

TF Family
RFX
Domain
RFX domain
PFAM
PF02257
TF Group
Basic Domians group
Description
RFX is a regulatory factor which binds to the X box of MHC class II genes and is essential for their expression. The DNA-binding domain of RFX is the central domain of the protein and binds ssDNA as either a monomer or homodimer [1]. It recognize X-boxes (DNA of the sequence 5'-GTNRCC(0-3N)RGYAAC-3', where N is any nucleotide, R is a purine and Y is a pyrimidine) using a highly conserved 76-residue DNA-binding domain (DBD) [2].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 2 2.9e-37 3.5e-33 114.5 0.0 3 78 244 319 242 320 0.97
2 2 1.3 1.5e+04 -2.9 0.0 24 33 654 663 641 669 0.71

Sequence Information

Coding Sequence
ATGTCCGAAATGGGATTTGAGAATGTGTTCTATTTAGAAAATTTTGAGTGCGCAGGCGACGAGGTTTTAGTCGAGTCGTCGCCGCCCGCCTCGCCCGAAATGGCGGCGCGACTCGCAGTGCCCTCGCAGGGCGCGGGCGGCGACGCGTCGCCAGACGCGGTCCGCGAGCTGATCGTCATACCCGAGCTACCGGACTCCATACAGCTGCAGCATGCTATACAACAGGTTTCCAGCGTCGTTGGGGATGTGAACGGTGGCAGTTCTGGAGATTCCAGCCCCTCTGGTGAGACGCAGCATACCTACATCACTGTTGCCATGCAGGGCGCATGGGCCGAAGATGTCACCACTGAACGAGTCAAATCCGAGGAACAAAGTGACCAAGAAAGCGAGGGCAGTAATGGCGTTAACTACCACGTACAATACGTTACAGAACCTCAGGATATATACGCTCAGAGCCACCAGACGCACATGGAGGCGCTGCGCTCGTACCCGGTGTACGGCGTGGCGGTAGGCGCGGAGGGGGCGGAGGGCGCGAGCGTGGCGACCGCGGGGGGCGTGGGGGGCGCGGGGGGCGCCGCGCCCGACGCCGCCGCCGCCGCCTGGGGGGGTGCCACCGCCGAGTACACCACCTATGGCGTTGTGGTGGCAGGCGACGAGGCGGAGACGGCGCCGTCGCCGGCCACGCCGGGCGCCGCGCCCGCCGCGCCCGCCGCGCCGCGCATGCCGCCCGCCACCGTGCAGTGGCTGCTCGACAACTACGAGACCGCCGAGGGCGTATCTCTGCCGCGTTCAACTCTCTACGCGCACTACCTGCGGCACTGCACCGCTCACCGGCTGGACCCCGTCAACGCGGCCTCCTTCGGCAAACTGATCCGTTCGGTGTTCATCGGCCTCCGAACCCGCCGCCTTGGAACCCGCGGGAACTCCAAGTACCACTACTACGGCATCAGGGCTAAGGGGAACGTTAATAATTCTCTCAGTCAAGACGAGGACAAAACTGACGTTGTTGATCAACAGGACGACAGTACAGGTTCTCCATCTCGCTCTTGCTCGCCGACCCCGGCCGGGGTAGCGGGTATCGCACACCGACAGTATCTAGGTTCGGTGATCGCACCGGACCCGCCCGCCTTGGTGGTACACGACCTGCCAGATGACATACCGCCTAGTGCCCTGGTTGCTCTCAATAATCATCACCGCGAGCACGGCGTGGAGTTCCTGGAGGCGGTGGCGGCGCTGGACATCGCGGGCGTGGAGCGCGCGCGGCGCGTGTTCTGGCGCCGGCCCGCCGCCGCCGCGCTGTGCCGCCGCGCGCTGGCGCGCCTGGCCGCGCGGCGCGACGTGGCGGCGTGGCTGCGCGCCGCCGACCTGCAGCTGTACCAGCGCGCCGTGGAGCTGCTGCTGCCCGACGTGCTGCGCCCCATCCCGCCGCAGCTCACGCAGGCCATCCGCAACTTCGCCAAGTGCCTGGAGGCGGCGCTGGGCGCGCGCGGCGGCGGGGCCGACGCCCCGGCGGCGGCGCGGCGCGCGCAGGCGGCGGCGGCGGCGGCGCTGGCGGCCGCGCTGCGCCGCTACACGTCGCTCAACCACCTGGCGCAGGCCGCGCGCGCCGTGCTCACCAACCACCACCAGATACACCAGATGTTATCTGACCTGAACCGCGTGGACTTCCGCGTGGTGCGTGAGCAAGCCGCGTGGGCCTGTGCCTGCTCCACACGGGACACTGCACACCGACTTGAGGCCGACTTCAAGGCGACGCTGGGGCGCGGCGCCACGCTGGAGCAGTGGGCGGCGTGGCTGGAGGCGTGCGTGCGCACCGCGCTGGCGCCGCACGAGCGCCGCGCCGACTACACGGCGCGCGCGCGCCGCCTGCTGCTCGACTGGTCCTTCTACTCCTCGCTCGTCATCAGGGAGCTCACCCTCAGGTCGGCGGCGTCGTTCGGCTCGTTCCACCTGATCCGGCTGCTGTACGACGAGTACGTGTCGTACCTGATCGAGCGGCAGGTGGCCGCGCACCGCCGGCACCCGCCCATCGCCGTCATGCACCGCCATCGACACGAGGAGGACGATGATGAAAATGCGGACGAAGCCGAAGCTGGCCCAGCCGAAGCCGAACTCGAACACGAGGACGAGGAAGAGCACGAGCAGGAGTGGGAGTGGGACGACGACGACGAGGAGGACGACGAGCCAGTCGAGTGCAAGAAAGCCAAGCTGCCTGATTAA
Protein Sequence
MSEMGFENVFYLENFECAGDEVLVESSPPASPEMAARLAVPSQGAGGDASPDAVRELIVIPELPDSIQLQHAIQQVSSVVGDVNGGSSGDSSPSGETQHTYITVAMQGAWAEDVTTERVKSEEQSDQESEGSNGVNYHVQYVTEPQDIYAQSHQTHMEALRSYPVYGVAVGAEGAEGASVATAGGVGGAGGAAPDAAAAAWGGATAEYTTYGVVVAGDEAETAPSPATPGAAPAAPAAPRMPPATVQWLLDNYETAEGVSLPRSTLYAHYLRHCTAHRLDPVNAASFGKLIRSVFIGLRTRRLGTRGNSKYHYYGIRAKGNVNNSLSQDEDKTDVVDQQDDSTGSPSRSCSPTPAGVAGIAHRQYLGSVIAPDPPALVVHDLPDDIPPSALVALNNHHREHGVEFLEAVAALDIAGVERARRVFWRRPAAAALCRRALARLAARRDVAAWLRAADLQLYQRAVELLLPDVLRPIPPQLTQAIRNFAKCLEAALGARGGGADAPAAARRAQAAAAAALAAALRRYTSLNHLAQAARAVLTNHHQIHQMLSDLNRVDFRVVREQAAWACACSTRDTAHRLEADFKATLGRGATLEQWAAWLEACVRTALAPHERRADYTARARRLLLDWSFYSSLVIRELTLRSAASFGSFHLIRLLYDEYVSYLIERQVAAHRRHPPIAVMHRHRHEEDDDENADEAEAGPAEAELEHEDEEEHEQEWEWDDDDEEDDEPVECKKAKLPD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01436751; iTF_01083037;
90% Identity
-
80% Identity
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