Basic Information

Gene Symbol
-
Assembly
GCA_956483585.1
Location
OY101443.1:1182504-1190230[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 14 4.4e-05 0.0047 18.5 0.5 1 23 9 31 9 31 0.99
2 14 0.00035 0.037 15.6 0.2 1 23 37 59 37 59 0.93
3 14 1.4e-06 0.00014 23.2 0.9 1 23 65 87 65 87 0.97
4 14 0.00097 0.1 14.2 3.6 1 23 94 116 94 116 0.96
5 14 5.8e-06 0.00062 21.2 1.6 1 23 122 144 122 144 0.97
6 14 1.2e-05 0.0013 20.2 3.9 1 23 150 172 150 172 0.99
7 14 0.0011 0.11 14.1 2.2 1 23 242 264 242 264 0.98
8 14 1.1e-05 0.0011 20.4 0.6 1 23 274 296 274 296 0.98
9 14 8.7e-06 0.00093 20.7 1.6 1 23 302 324 302 324 0.92
10 14 8.4e-06 0.00089 20.7 0.1 1 23 330 352 330 352 0.96
11 14 0.00012 0.013 17.1 1.0 1 23 359 381 359 381 0.96
12 14 2.3e-07 2.4e-05 25.7 1.3 1 23 387 409 387 409 0.98
13 14 1.3e-06 0.00014 23.2 3.5 1 23 415 437 415 437 0.99
14 14 0.013 1.4 10.7 0.3 1 23 443 465 443 465 0.97

Sequence Information

Coding Sequence
ATGCATGATAGTAAAGAACAAACATACAAATGTTCAATATGTAAAGAAGTATTTGATGAGAGATCAATATTAAAAGATCATATGCGAATGCACAGtgGCGAAAAGGTATTTTTATGTTCGGAATGTGGAAAAGGATATACAACAGCGGGAggtttgaaagaacattcatatcgccatttaaatgaaaaaaacttttcttgtCCTGACTGTCCGCGCTCGTTTACAACCAAAACCGATCTGGTATCACATCATATAATTCATAAGGCGAAACCGAAAAATCACATTTGTGACATATGTGGACGCGGTTTTCACAAGCCTTTCCTattgaaaaaacacaaaatgtatCACAATAACGAAAGACCATTCGCCTGTGAGTTTTGTGAAAAACGCTTTGTcacaaatgaaaaactaaaacgtCATACTCGCATTCATACCGGTGAAAAACCTTACAAAtgcaattattgcaaaaatgcCTACTGTCAGTCTAGTGAACTGATAAAACATTTGCGATCCCATTTAGGCGAAAACGTCTATCAATGTGAAATAAATACTACAATAACTGACAAATCTAAAATACTTAAACAAGAAGAATTTGATGATGAAGTATTCGTATCAGTTACATacgatgatgatgaagatgttaaagatgatggtgatgatgaggACTATGAAGATATAGTAAATACAAAAGCACTAAATAAGGAATTTACTGTGGAACAAATTTATCCATGTGATagatgtaaaagaaaattaaaatctaaactATCATTAAAAAAGCACCAAGAAATGCATGCGAAACGTGACACTGAGGAACCTAAATTTATGTGCAATATTTGTGAGAGagGTTTTTCACAAGGCTACATGCTAAAAGATCATCTACGTACGCATAGTgGTGAAAAACCATTTTTGTGTTCGGAGTGTGGTAAATCCTTTACATCATCCGGCAGTTTAAAACAGCATTCATTCCGCCATCTAAATGAAAAGCAATTTGCTTGTCCGGGCTGCCCTAAAACGTTTCCAACCAGAACGGATTTAGCTTCTCATTATGATGTTCATAAAGCAAGGCCTAGAACACATATTTGTGATGTCTGTGGTCGTGGTTTTCCAAAAccgtttcttttaaaaaagcataaaatgtATCACACTAACGACAGACCGTTTTCTTGCGAATATTGTGATAAACGttttataaccAACGAGAAACTGCAACGACATGTAAGAATCCATACTGGGGAAAAGCCGTACAAATGCAACTATTGCGAGAAAGCCTACTGTCAGTCTAATGAATTAACCAAACATTTACGAGTTCATTTGGGCGATAATGTGTATCAATGCGAATTATGTCCTCTAAGATTTCCGACAGTTAAAGCAGTTCGAGAGCACTTCTATACACATAAAAACGATGATGAAGAAACTAAAGCTCGCAATTTGGCAGAACTCAATGCTACTACATTAAAAGGAATTTATTGTagataa
Protein Sequence
MHDSKEQTYKCSICKEVFDERSILKDHMRMHSGEKVFLCSECGKGYTTAGGLKEHSYRHLNEKNFSCPDCPRSFTTKTDLVSHHIIHKAKPKNHICDICGRGFHKPFLLKKHKMYHNNERPFACEFCEKRFVTNEKLKRHTRIHTGEKPYKCNYCKNAYCQSSELIKHLRSHLGENVYQCEINTTITDKSKILKQEEFDDEVFVSVTYDDDEDVKDDGDDEDYEDIVNTKALNKEFTVEQIYPCDRCKRKLKSKLSLKKHQEMHAKRDTEEPKFMCNICERGFSQGYMLKDHLRTHSGEKPFLCSECGKSFTSSGSLKQHSFRHLNEKQFACPGCPKTFPTRTDLASHYDVHKARPRTHICDVCGRGFPKPFLLKKHKMYHTNDRPFSCEYCDKRFITNEKLQRHVRIHTGEKPYKCNYCEKAYCQSNELTKHLRVHLGDNVYQCELCPLRFPTVKAVREHFYTHKNDDEETKARNLAELNATTLKGIYCR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01399683;
90% Identity
-
80% Identity
-