Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 0.0077 52 5.9 0.3 19 49 78 108 71 112 0.79

2 7 0.00023 1.6 10.8 0.1 22 49 110 137 106 142 0.89

3 7 0.0013 8.4 8.4 0.2 26 48 143 165 139 170 0.89

4 7 0.28 1.9e+03 0.9 0.5 22 49 168 195 166 199 0.78

5 7 0.00053 3.6 9.6 0.7 22 48 197 223 192 228 0.88

6 7 0.015 1e+02 5.0 0.2 22 48 226 252 224 259 0.76

7 7 0.00072 4.8 9.2 0.2 17 50 279 312 273 314 0.87

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	0.0077	52	5.9	0.3	19	49	78	108	71	112	0.79
2	7	0.00023	1.6	10.8	0.1	22	49	110	137	106	142	0.89
3	7	0.0013	8.4	8.4	0.2	26	48	143	165	139	170	0.89
4	7	0.28	1.9e+03	0.9	0.5	22	49	168	195	166	199	0.78
5	7	0.00053	3.6	9.6	0.7	22	48	197	223	192	228	0.88
6	7	0.015	1e+02	5.0	0.2	22	48	226	252	224	259	0.76
7	7	0.00072	4.8	9.2	0.2	17	50	279	312	273	314	0.87

Coding Sequence: ATGTTGTTGACACCAGGATCCTCTTCAAGGATGCCTGGAGCAGACGTGGTAGGCTTGTGTAATCAAAGCTGCTATTACAAGCTCAGTTTTACTTCAACAGAAGAAGAGAAGTTACCTGTCTATGAGGTGCCTGATAATACAGAAGCTTTTGATAATAGCAATGAAACTTCTTACTTAGTTACCAATCATAATTACGAGACAGTTCATTCGAATGAATTCACACATTACTCATCGAAAACAGACCGTATCCACAAGTGTCCTTATTGCAATTACAGTTCAGTAAAGACTCAATCTTTGAAACGTCACATCATGTATAAACACATTAATGACAAACCTCACTCCTGTCCTGCATGTACGTACACAACAGTAGAGGCAGGAAATTTAAAGCGTCACATCATGTATAAACATGTTAATGACATGCGTCTCGCCTGCCCTCAGTGCACTTACACAACAGTGGAGGCTAAAAATTTAAAGCGTCACATCACATATAAACATACAGATAACAGGCCTCACTCTTGTCCTCATTGCAAGTACAGAACTGTTGAGCCATACAGTTTAAAGCATCACATCATGACTAAGCATTTGAATAACAAACCTCATGCCTGTCCATACTGTACTTACACAACGGATGCTACTAGGAATTTACATCATCatatcatgtataaacatactCACGACAAACCAAATTCTTGTCCCTTATGCGATTATAGATCTGTTAATCCCAGTAGTATAAAACGCCATATCATGTATAAACATTCTGAAAACAAACCATATGCCTGTAGTCAGTGTGACTTCAAAACAGTTGAGGCTTCAAGTTTAAAGAATCATGTTATGTCTAAACATACTAATAACAAACCTCAATCCTGCCCGCATTGTCCTTACACCACCGTTATGGCAAGATACCTGAAGCAACATATTGTATCTAAACATTTTCAGACAAAGGTCTAA
Protein Sequence: MLLTPGSSSRMPGADVVGLCNQSCYYKLSFTSTEEEKLPVYEVPDNTEAFDNSNETSYLVTNHNYETVHSNEFTHYSSKTDRIHKCPYCNYSSVKTQSLKRHIMYKHINDKPHSCPACTYTTVEAGNLKRHIMYKHVNDMRLACPQCTYTTVEAKNLKRHITYKHTDNRPHSCPHCKYRTVEPYSLKHHIMTKHLNNKPHACPYCTYTTDATRNLHHHIMYKHTHDKPNSCPLCDYRSVNPSSIKRHIMYKHSENKPYACSQCDFKTVEASSLKNHVMSKHTNNKPQSCPHCPYTTVMARYLKQHIVSKHFQTKV

Sequence clustering based on sequence similarity using MMseqs2