Basic Information

Insect: Gonocerus acuteangulatus
Gene Symbol: Hr39
Assembly: GCA_946811585.1
Location: CAMPFD010000711.1:27904-50001[-]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 0.26 8.7e+03 -2.4 5.9 71 172 162 282 104 291 0.69

2 3 2.8e-09 9.4e-05 23.9 0.0 1 30 401 430 401 438 0.89

3 3 1.7e-68 5.6e-64 219.0 0.0 166 408 440 677 430 677 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	0.26	8.7e+03	-2.4	5.9	71	172	162	282	104	291	0.69
2	3	2.8e-09	9.4e-05	23.9	0.0	1	30	401	430	401	438	0.89
3	3	1.7e-68	5.6e-64	219.0	0.0	166	408	440	677	430	677	0.90

Sequence Information

Coding Sequence: ATGGAGGGCGGCCTCAAGTGTAGACCCAGCTCGGCAGGGGTAACCCTGTCTCTCAGGTCCCCCTCTCTTTCTGTAACAGacaaAGATCAGAAGTATTATCAGCCCCATTGTAACAGCGAGCTTATATCTTGTTCAAGCAGCGCCTGTTCTGTAGTAATAAGCAATGAACAAATGAATGTTGATGAAGACTCGTCCGCAGCTGATGCTGAAGTCAGCACCTTCACTAGTGATACCgtaaacttaAGGCATAAGCATGGAGAAGAGTCGCGAACTCCAATGGAGCGACCGATGTCATGGGAGGGAGAGCTATCAGACTCTGAAGTTGCAACAGTTAAGGCTGAACCAGAAGATGCCTCTGAAGGTGGAGAAAACTCTAATCCTGGAAAGACTGCTAGATCAAAAGGGACTGAAGAACCACCTCAGCCTTTAAAACTAAACAACGAGACAATCaatgaaaaagttttGGAACAATCAAGGACAAATCATTCAAATGCTCAATCTGAGCTTCCTCTATTAGTGGATAAAATACTAAGTAGTGGTGGTTACCTAAAAGGCGCTGGACCTACACCTAGCCCCGACTCTGCAGTGTATTCTTGCTACTCGCCTACGGCTAGTCCAGTCACCTCTCGACATATCTTATCATCATCATCAGGAATATCAAGCCCCTTTACACCGTCCCTATCTAGGAACAATAGTGATGCTTCCCAATACGGAGGTTCCCAGCATTCATCGTGCTATAGCCATAGTTACTCATCTGTGTCTGTATCTCCGACTCAGTTTTCTCCCACTCATTCTCCTATCCAGGGAAGGCACATTCCTAGGCCTGGCTTTCCCTCTCCAGTCCTCAACAGCAGGACTGTCCACGACTATTCCCTCCAAGATGATGGAACTGTGCTGGAAGATAAGTTTTCCTCCCTGACTGCGGACATGGTCCAGCATTCAGCTGGCCTTGCTTCACCGGGAATCAGCAGACAGCAGCTTATCAACAGcCCGTGCCCTATATGTGGTGATAAAATCTCAGGTTTTCATTATGGCATATTCTCCTGTGAAAGTTGTAAAGGGTTCTTCAAAAGGACTGTTCAAAACAGGAAGAATTATGTCTGCCTGAGAGGCTCATCTTGCCCTGTAACTATTGCTACAAGAAAAAAATGCCCAGCTTGCCGATTTGATAAGTGCCTTAACATGGGCATGAAGTTAGAAGCCATTAGAGAAGATAGAACTCGTGGAGGTCGAAGTACTTACCAGTGTTCGTACACCGTGCCAGCTAATCTTGTTGAGCAGAAGTGTGCGGAGTTGAGGCAGGAACCCTCTGCCCCTACTTCTCTCATTCCACCTCTCCTCCAGgaaATTATGGAAGTAGAACATCTGTGGCAGTACAACGAGGGTGAATCCAGGGTTGGTGGTGTCGGGAGATCTCCACAAACTGGTGGCGGAAATTCCACCGATCTCATGGCTAACCTTTGTAATATTGCTGACCATCGACTATACAAAATAGTCAAATGGTGTAAATCTTTGCCATTGTTTAAAAACATATCAATTGATGACCAGACATCTCTTCTAATCAATGCTTGGTGTGAGCTCCTTCTCTTTTCTTGTTGCTTTCGCTCGATGAGTTCTCCTGGTGAAATCAGAGTCTCACTTGGGAAGTGCATCTCTCTCCCAGAAGCTAGGAACCTTGGACTTGGTCCGCCAATAGAGCGAATGCTCAATTTTACCGAACATCTGCGACGGCTGAGGGTAGACCGCTATGAATATGTTGCAATGAAGGTCATTGTTCTCCTGTCGTCAGATACAAGTGAGCTTCGTGAACCTGAAAAAGTGAGAGCTTCACAAGAAAAAGCATTGCAAGCACTGCAGCATTATACGCTGGCCCACTACCCAGACATTCCGTCCAAGTTCGGTGAACTCCTACTCAGGATACCTGACCTACAGAGGACCTGTCAGGTTGGGAAAGAGATGTTGTCTATTAAAAGCAAAGAAGGGGAAGGACCCAGCTTCAATTTGCTCATGGAACTCTTGAGAGGTGACCACTGA
Protein Sequence: MEGGLKCRPSSAGVTLSLRSPSLSVTDKDQKYYQPHCNSELISCSSSACSVVISNEQMNVDEDSSAADAEVSTFTSDTVNLRHKHGEESRTPMERPMSWEGELSDSEVATVKAEPEDASEGGENSNPGKTARSKGTEEPPQPLKLNNETINEKVLEQSRTNHSNAQSELPLLVDKILSSGGYLKGAGPTPSPDSAVYSCYSPTASPVTSRHILSSSSGISSPFTPSLSRNNSDASQYGGSQHSSCYSHSYSSVSVSPTQFSPTHSPIQGRHIPRPGFPSPVLNSRTVHDYSLQDDGTVLEDKFSSLTADMVQHSAGLASPGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCLRGSSCPVTIATRKKCPACRFDKCLNMGMKLEAIREDRTRGGRSTYQCSYTVPANLVEQKCAELRQEPSAPTSLIPPLLQEIMEVEHLWQYNEGESRVGGVGRSPQTGGGNSTDLMANLCNIADHRLYKIVKWCKSLPLFKNISIDDQTSLLINAWCELLLFSCCFRSMSSPGEIRVSLGKCISLPEARNLGLGPPIERMLNFTEHLRRLRVDRYEYVAMKVIVLLSSDTSELREPEKVRASQEKALQALQHYTLAHYPDIPSKFGELLLRIPDLQRTCQVGKEMLSIKSKEGEGPSFNLLMELLRGDH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00373210;
90% Identity: iTF_01095869;
80% Identity: iTF_00757378;