Basic Information

Gene Symbol
-
Assembly
GCA_018342105.1
Location
JAFIRS010000052.1:1314833-1323463[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 14 0.017 1.9 10.1 0.5 3 23 55 75 54 75 0.98
2 14 0.12 13 7.5 3.6 1 23 79 101 79 101 0.98
3 14 0.02 2.4 9.9 1.8 1 23 107 129 107 129 0.99
4 14 8.3e-06 0.00095 20.5 0.2 1 23 135 157 135 157 0.95
5 14 4.5e-06 0.00052 21.3 0.2 1 23 163 186 163 186 0.98
6 14 4.1e-05 0.0047 18.4 2.6 1 23 192 214 192 214 0.97
7 14 0.001 0.12 14.0 0.5 2 23 221 242 220 242 0.97
8 14 1.9 2.2e+02 3.6 2.5 3 23 251 271 250 272 0.88
9 14 1.2e-06 0.00014 23.2 4.2 1 23 285 307 285 307 0.99
10 14 1.1e-06 0.00012 23.3 1.4 1 23 314 336 314 336 0.98
11 14 4e-05 0.0046 18.4 1.8 1 20 342 361 342 364 0.93
12 14 0.00066 0.076 14.5 4.4 1 23 370 392 370 392 0.97
13 14 1.1e-05 0.0012 20.2 0.6 1 23 398 420 398 420 0.98
14 14 1.6 1.8e+02 3.9 0.3 1 19 484 502 484 504 0.94

Sequence Information

Coding Sequence
ATGGAACCAATCGCACTCCCACTAGAACAAATAACAATCAAACAAGAGCCTTGCGATGAACCCCCCGACTTCAACAACTGGAATGTGGAGAACAACCCCTGTGACAAGCTACTCAAAGTCGAGATACTGGAGCCCGATAGCGCCGACACCGAAAAAATGTTATGCAAAGAATGCGAAGCTCTGTTCGTCAACGAACACGAACtgaaaatacacaaaatgatacACTCGCCCAATCACACCTGCTTCATCTGCAAAGAGTTCGTCAAGAACAGATTCCAGTTCGTAGGACACGTCAGAAAACACATGTGCGCCAAGCCCTTCAAGTGCCCCAGTTGTATACGGACGTTTCAAACCTCTAGGGAGACGAAGTTACATCAACGCGTTCACAGTGAGAATAGGCCGTATATGTGCACCGAATGCGGGAAGGCGTTCAAACAAATATCCACTTTGAAGGACCACGAGGTGGTCCACACTGGGGAAAAGAAATTCAAGTGTAAGATTTGTGAGGGAGCCTTCGCGACAGCCACCAGCTTGAGGCGGCACATTCGTGTTATGCATGAAACAGTCCGCTCGTTCCGCTGCCATTTCTGCAAGGAAGGATTCACGAGCAAACAGGCCCTCAAACAACACATGGGCATACACAAAGACATCGACCCCCTCAAATGCCAACTTTGCGGAGAACGTTCGAGAGATTTGGAGGAATTCACGGCGCACAGGAACAGGCACATCGAGCTGAAACAGTCTGGAAATTGCGAATACTGTGGCAACAAGACGTTTTACTTCGAACTGAAGGATCACATTCAAAAGATGCATCATCCGAGGAGCCACTTGGAGGAGCCTGAAAGAGAAGAGTATGTTTGCCACATCTGTGGGAAGCATTTTGAGTTTCCTAGGTACCTGAAGGCGCACATGAAGAGGCACGAGGAGGACTACAAGAAATTCAGGTGCGATTTGTGCCAGAAAACATTCTCCTCCAAGCGCGACCTGACGGATCACCTGAACGTGCACGCCAACGTCAAGAACTACCACTGCAAGGTGTGCGACAAAGCATTCCGCACGAAACAGAGCGTCAACAAGCACATGCCGATACATTCCGAGAAACGCCCCTTCAAATGCACCCTCTGCGACAAGAGATTCAAGAAGCAATCGATCCTGCGCAAGCATTCCTTCACGCATTCGAGGTTGCGGCCGTACGCGTGCGATTTGTGCCCCAAAAACTACAAATCCAAAGAGAGCCTCCGGGTGCACAGGCTGACGCACCAGAAGAGGAAGAGAAAGTGCAAAGCTTGCAAGAGACTGTTCGCTTTCGAGACTGTCTACAAAAAGCACGAGTGTTTCAGCAGGTACAGGTTCGACGTCAATAATCGGCGGTGTTATTTCTGCAAGAGGCAGTGCAAGAGCAGTGCCACGCACGCTTATCACGTCCAGGGGCACTCTAGGGCAAAGTTGTTTTCTTGCAGCACTTGCAAAGTTCCTCTTAAGTACTCGTATCAAGTTAAGTTGCACGAGGTTATACAAGGAAGGGTGGGTCGACTAAATAGGGTGAGTGAAGGATGGTGGTACCTGAGAAATAAacttgatttattattttatctgttCGATTATGGCGGAAGTGGACTTTGTTTCGCTATAAGAAACACTGGATTGTACCCAAAAGATACTTTCACTTCTTCATAA
Protein Sequence
MEPIALPLEQITIKQEPCDEPPDFNNWNVENNPCDKLLKVEILEPDSADTEKMLCKECEALFVNEHELKIHKMIHSPNHTCFICKEFVKNRFQFVGHVRKHMCAKPFKCPSCIRTFQTSRETKLHQRVHSENRPYMCTECGKAFKQISTLKDHEVVHTGEKKFKCKICEGAFATATSLRRHIRVMHETVRSFRCHFCKEGFTSKQALKQHMGIHKDIDPLKCQLCGERSRDLEEFTAHRNRHIELKQSGNCEYCGNKTFYFELKDHIQKMHHPRSHLEEPEREEYVCHICGKHFEFPRYLKAHMKRHEEDYKKFRCDLCQKTFSSKRDLTDHLNVHANVKNYHCKVCDKAFRTKQSVNKHMPIHSEKRPFKCTLCDKRFKKQSILRKHSFTHSRLRPYACDLCPKNYKSKESLRVHRLTHQKRKRKCKACKRLFAFETVYKKHECFSRYRFDVNNRRCYFCKRQCKSSATHAYHVQGHSRAKLFSCSTCKVPLKYSYQVKLHEVIQGRVGRLNRVSEGWWYLRNKLDLLFYLFDYGGSGLCFAIRNTGLYPKDTFTSS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00328476;
90% Identity
-
80% Identity
-