Basic Information

Transcription Factor Domain

TF Family: PC4
Domain: PC4 domain
PFAM: PF02229
TF Group: Unclassified Structure
Description: This domain is found at the C-terminal end of Activated RNA polymerase II transcriptional coactivator p15 from humans, YdbC from Lactococcus lactis, and other PC4 family members. p15 has a bipartite structure composed of an N-terminal regulatory domain and a carboxy-terminal cryptic DNA-binding domain [1-4]. Activity is controlled by protein kinases that target the regulatory domain.
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 0.047 1.1e+03 -0.4 0.8 30 37 30 37 26 37 0.81

2 3 0.0058 1.3e+02 2.5 0.5 28 37 43 53 41 53 0.87

3 3 2.1e-28 4.7e-24 84.0 0.5 1 51 67 118 67 119 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	0.047	1.1e+03	-0.4	0.8	30	37	30	37	26	37	0.81
2	3	0.0058	1.3e+02	2.5	0.5	28	37	43	53	41	53	0.87
3	3	2.1e-28	4.7e-24	84.0	0.5	1	51	67	118	67	119	0.96

Coding Sequence: ATGCCTAAATCAAAAGAATACGTATCAAGTGAGGATGAAAGCAGTGAAGAGGAAGTGAAACCAAAAAAGAAGCGATCGAAGGGAGGCGAAGAAGAAAAACCAAGTAAAAAAAGCAAAAAAGAATCAAAAAGCGACGAAGAAGAAAAACCAAGTAAAAAAAGCAAGAAAGAGTCAAAAAGTGACGAAGAAGAAACAAGCTGGGACTTGGGATCTAATCGTCAAGTCAATGTCAGAGAATTCAAAGGAAAAACTTATGTTGATATCAGAGAGATGTATTATGACAAAGAAGGAGATCTGAAACCTGGCAAAAAAGGAATTATGTTGAATATGCCACAATGGCGCAAACTGGTGGATGTTTTTGAAGATGTCGATAAAGTGGCCAAATCTAAATGCTGA
Protein Sequence: MPKSKEYVSSEDESSEEEVKPKKKRSKGGEEEKPSKKSKKESKSDEEEKPSKKSKKESKSDEEETSWDLGSNRQVNVREFKGKTYVDIREMYYDKEGDLKPGKKGIMLNMPQWRKLVDVFEDVDKVAKSKC

Sequence clustering based on sequence similarity using MMseqs2