Gbil015693.1
Basic Information
- Insect
- Gnoriste bilineata
- Gene Symbol
- Lztr1
- Assembly
- GCA_026546565.1
- Location
- JANSWN010012368.1:6070-9097[+]
Transcription Factor Domain
- TF Family
- BTB
- Domain
- zf-C2H2|ZBTB
- PFAM
- PF00651
- TF Group
- Zinc-Coordinating Group
- Description
- The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 4 1.9e-15 4.8e-13 49.4 0.1 2 107 409 534 408 537 0.85 2 4 0.93 2.3e+02 2.2 0.1 76 108 535 567 532 569 0.90 3 4 1.8e-20 4.6e-18 65.6 0.0 8 106 627 727 621 731 0.86 4 4 2.3 5.7e+02 0.9 0.0 77 104 730 757 725 762 0.80
Sequence Information
- Coding Sequence
- atgaaacaaataagatctaactcaaataacaccagcagcggcagcagcaatgccagtatcagcagcagcagcagcggcagcaacaccagcttcaccaacaatagcagcggaggcagtaacaaattgatgcaaagcagctcaacatcaatgaaaagctacaaaaatgccgtcatttacaatgcaactccagcagGTGAAAATTCTCTCAATTTAGATTTCACACCATTCGAAACAATTCACCAATGGAAACGTATGCTGGAATGCGACGAATTTGTGGGCGCCAGACGAAGCAAACACACGGTAGTCTCATTCAAAGATGCCATATACGTATTTGGCGGTGATAATGGCAAGAATATGCTAAATGATTTGATACGATTCGATGTCAAAGATAAATCATGGGGTCGAGCATTTGCAACGGGAACACCACCGGCAGCTCGTTACCATCATTCGGCTGTCGTACATGAGTCATCGATGTTTGTCTTTGGCGGTTACACTGGAGACATTCACTCGAATTCGAATCTTTCCAATAAGAACGATTTGTTCGAGTATAAATTTCAGAATGGACAGTGGTTGGAATGGAAATTCATTGGACGTAGTCCAGTACCACGATCAGCACATGGTGCTGCAGTTTATGATAACAAACTATGGATTTACGCTGGCTACGATGGCAATGCTCGTCTTAATGACATGTGGACGATGTCACTGAATAACGACTATCGTCAATGGGAAGAGATCGAACAAAAAGGTGATCAACCGCCAACGTGTTGTAATTTCCCAGTAGCTGTTGCCCGTGGATGTATGTACGTTTTCTCTGGTCAAAGTGGTTTGCAAATTACCAATGCTCTATTCGAATTCACATTCAAAACTAAAACTTGGCGTCGCATTTCAAATGAACATATTTTACGAGTAACTCCTCCACCACCAGCCCGACGATATGGCCATACAATGGTTACTCATGATCGATTCTTATACGTGTATGGTGGATCTGCAGATAGTACTTTACCGAATGATTTGCATTTCTATGATCTCGATTCTCAAGTATGGTCAGTTATTATTCCGGAAACAGATTCACAAATTCCGACGGGCCGTGTATTTCATGCGTCGGCCGTAATCAATGATGCAATGTACATATTTGGTGGTACCGTCGATAATAATGTTCGCAGCGGTGATATGTATCGCTTTCAGTTTTCCAGCTATCCCAGATGCACGTTACACGATGATTTTGGCAATTTTCTGAAAGAACGTCAATTTTGCGATGTTTTGTTTATTGTTGGACCTGATGAGGTGAAAGTTGGCGCACACATTGCAATGATAGCGGCTAGATCACAATTCTTGCGTGACAAAATTCTTGATGCACGATCAATGCTAAACGCTCAAATGCTTGAGGCTGGTGAGATTACTGAACGACCATTACTTGAAGTTCAACTACCAACCGCTGAACCCGAAGCATTTGAAATGATTCTTAACTACATCTACACCGATCGAATTGATTTCAATAATCAACACAGTAATCGGATTGTCATTCTCATGATGGACATTTATCAATTGGCCGTCAAATATTTGATTCCACGTCTAGAACAGGTGTGCATTCAGTATTTAGAATTTAAAATATCCAAACAGAACGTATTGGATGCTCTTTACAATGCTGACAAAATGGCATTGACTCTGATCAAAGACTTTTGTTTGAGTTTTATTGTGAAAGAGGATAACATTTACGAAATTGTCATGTCTAATGAGTTTGGTAGTCTGGACAAGCCATTGATGGTAGAGATAATTCGTAAACGTCTTAATCCTGGTAAATTCATTGAAATTAAATACGACAAAATCGAAGGTACCACGCTGGAAAATGATTTGGCCGTGTTCCTTAAGACGGGCGGAAAAGAATTCTGTGATATCAATTTGATTTTGGATGGTCACACGATTCCGGCACATAAATCGATTCTATCGGCGCGTTGTACTTACTTCCAAGCCATGTTTCGTTCATTTATGCCTCGCGATAATTCTGTCAACATTCAAATCGGAGACATTTCACCATCACTCGAGTCATTCCATTCGCTGTTACGTTACATTTACTATGGAGACAAAAATATGCCACCCGAAGATTCACTGTACTTGTTTCAGGCCCCTTCTTTTTATGGATTTACTAATAATCGCCTACAGGCATTTTGCAAGCATAATCTGGAGCATAATATTCACTTTGACAATGTGCTACAAATTCTTGAGGCTTCGGATAAAATGAACGTGCCGGATATCAAGAATTTTGCGCTACGCATGATTGTGCATCATTTTTCACAAGTTTCTGGGCTACCAATGATGAAAGAGCTTAGCCGTGATCTTTTGCTAGAAGTGATCCAAGCGGTCGGTGAAGTATTGGGTGAAATACGATTAAACCAAGACTATGCATCGATCAGCATTCATGGTGATTTATGA
- Protein Sequence
- MKQIRSNSNNTSSGSSNASISSSSSGSNTSFTNNSSGGSNKLMQSSSTSMKSYKNAVIYNATPAGENSLNLDFTPFETIHQWKRMLECDEFVGARRSKHTVVSFKDAIYVFGGDNGKNMLNDLIRFDVKDKSWGRAFATGTPPAARYHHSAVVHESSMFVFGGYTGDIHSNSNLSNKNDLFEYKFQNGQWLEWKFIGRSPVPRSAHGAAVYDNKLWIYAGYDGNARLNDMWTMSLNNDYRQWEEIEQKGDQPPTCCNFPVAVARGCMYVFSGQSGLQITNALFEFTFKTKTWRRISNEHILRVTPPPPARRYGHTMVTHDRFLYVYGGSADSTLPNDLHFYDLDSQVWSVIIPETDSQIPTGRVFHASAVINDAMYIFGGTVDNNVRSGDMYRFQFSSYPRCTLHDDFGNFLKERQFCDVLFIVGPDEVKVGAHIAMIAARSQFLRDKILDARSMLNAQMLEAGEITERPLLEVQLPTAEPEAFEMILNYIYTDRIDFNNQHSNRIVILMMDIYQLAVKYLIPRLEQVCIQYLEFKISKQNVLDALYNADKMALTLIKDFCLSFIVKEDNIYEIVMSNEFGSLDKPLMVEIIRKRLNPGKFIEIKYDKIEGTTLENDLAVFLKTGGKEFCDINLILDGHTIPAHKSILSARCTYFQAMFRSFMPRDNSVNIQIGDISPSLESFHSLLRYIYYGDKNMPPEDSLYLFQAPSFYGFTNNRLQAFCKHNLEHNIHFDNVLQILEASDKMNVPDIKNFALRMIVHHFSQVSGLPMMKELSRDLLLEVIQAVGEVLGEIRLNQDYASISIHGDL
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01265910;
- 90% Identity
- -
- 80% Identity
- -