Basic Information

Insect: Glossina palpalis
Gene Symbol: zfh1
Assembly: GCA_000818775.1
Location: Scaffold430:105882-110257[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.00053 0.042 14.5 1.6 1 23 343 366 343 366 0.97

2 11 0.01 0.8 10.4 0.4 1 21 434 454 434 455 0.95

3 11 1.9e-05 0.0015 19.0 0.2 1 23 463 485 463 485 0.99

4 11 0.0068 0.54 11.0 0.6 2 23 490 512 489 512 0.95

5 11 2.7e-06 0.00021 21.7 1.5 2 23 519 540 518 540 0.98

6 11 2.9e-08 2.3e-06 27.9 1.7 1 23 546 568 546 568 0.95

7 11 0.0018 0.14 12.8 0.6 1 23 574 596 574 596 0.99

8 11 3.9e-07 3.1e-05 24.3 1.9 1 23 602 624 602 624 0.98

9 11 0.016 1.2 9.8 0.6 1 23 630 652 630 652 0.98

10 11 2.4e-05 0.0019 18.7 5.4 1 23 658 680 658 680 0.99

11 11 0.00093 0.074 13.7 1.7 5 23 688 707 686 707 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.00053	0.042	14.5	1.6	1	23	343	366	343	366	0.97
2	11	0.01	0.8	10.4	0.4	1	21	434	454	434	455	0.95
3	11	1.9e-05	0.0015	19.0	0.2	1	23	463	485	463	485	0.99
4	11	0.0068	0.54	11.0	0.6	2	23	490	512	489	512	0.95
5	11	2.7e-06	0.00021	21.7	1.5	2	23	519	540	518	540	0.98
6	11	2.9e-08	2.3e-06	27.9	1.7	1	23	546	568	546	568	0.95
7	11	0.0018	0.14	12.8	0.6	1	23	574	596	574	596	0.99
8	11	3.9e-07	3.1e-05	24.3	1.9	1	23	602	624	602	624	0.98
9	11	0.016	1.2	9.8	0.6	1	23	630	652	630	652	0.98
10	11	2.4e-05	0.0019	18.7	5.4	1	23	658	680	658	680	0.99
11	11	0.00093	0.074	13.7	1.7	5	23	688	707	686	707	0.95

Sequence Information

Coding Sequence: ATGGATGTTGAAAAGATCTGCAGAACGTGTTTAACATTAAATGGTCCATTGCTTTCAATTTATGATGATGGTAAGGGTGGTTCTGGTTGTTTGGCTGATATGTTACGGGAATTCACTAAAACCAAGCCTCAGTGTAACGACAACCTACCGGAACGCGTATGCCTTTCATGCATAAGTGAAATTAACCGCTGTTATTCATTTAAATTGAAATGTGAAAATTCCAGCAAAACACTCCAACAATTAATACCGAATGCCGCCAAAGGCTTGCCAGACGTTACCGAAAAGTCGGTATCTAACTGTGAAAAGGCAGTGCAGACAAACAAAAAAGCACTTATCTCTACATATGTTCAGACGTTTGCTTTGTTCAAGGACAAGGAAATACAAACTGAAGCACGAGATGCAATGCAAAATTTTAAATTTGAAAGATCTTCAGAGCTCTCAAACGCTCCACGCTCCAACAATCCCGTCCGTTGTTTTAAGCGTTCGACAGACTTAGAAGCAAACGTTCACACGTTGCCTCGTCaaaaaaaTCCTGATAAAGTTTGCAATAGACTGTGCTTTGACACTAATTTAAAAGATACTGCTCTGAAAGCAGCGGAAATGGCGCGGGAGGAAGCCTATATTCTATTAGATAACAGTTCAACAGAAAATGATAAGTTTTACATACGTAGTGAATCAGATAATATAGGAGCGCAGGATTCGATCAACGTTGTTTTATCGAATCATTTCGAATTTTACAATGACGAAGACGAACTCGATGAAGATAATCGAACGGAGGAACATGATTACTCTTGTGGAAATGTGGACATTCCTGACATCAATTGTGCAACAGATCAATCACTAGTCGCCAACGGTGTGTTGTGTAAAATTAATAGACACTTTGATTCCGCTTCTGATGAAGATGGCCACAGCTGGGATAAGGAGGAACACAGAGCAACAAACTCTGCCAGCTCGCAACTCGCAGACAAGCAGTCTGGTCCTGTAGCAATCATTAGCTCAAGTCGTTTGGATTCAAATAGGGAAGAGTACCGATGCCCATACTGTATTATGACTTTCGTCAGCTTGAAAACTCTCAGGCGTCATTTATCCAAACGCCACAACCTAGAACTTGAACCATCCCAAATTATTATTGAGaaaaaagtaaaaaaaTCTGTTGAAACCATAGAGGAGATGATTGATGAATCTGCAGGCAATGAGCAGAAAAACTTGACAAAGGGAAATGTACTAAAGCCTCACTTAATGCCGCGAGACCGTGTTTCAACTTCTAAATCGGACGAAGCCGCATTAACCACTTTTCAATACTTTTGCGATTATTGTAAAGCTGGCTTTGCATTGCGCAAAACTCTAACTTTGCATATGAATCAAAACTTGTGCACCTCCAATAATTTTAAGTGCGACACATGTGGAAAAATTTTCTTAACCGAAAAGAATTTAGAAGCACATATCGCTACGCACACGAATGAACAAACTTGTTTGGAGTGCAAGAAAACATGTGGGAGCATAGAGGAACTTAGCGCACACATGATTAGTGAACATAATCGAAATCCCCGCAATCAGTGCAAAGTTTGCAAAAAAGTATTCACTATGAAGACATCGCTTATGGATCACATGCGCATACATTCCGGTGAAAAGCCATTTCTCTGTACAATATGTGGGAAAAGCTTTCGTCAAAACTCAAACTTACGACAACACTTAATGCGACATACGAATGAGAAAAATTTTAAGTGTGATGTATGTTTAAACGCTTATGTAACCAAAGCTGAATTGTTTTCTCATAAACGTTCACACACTGGTGATCATCCGTTTAACTGTGAAATATGTGGATCGAGTTTCACATCTTCAAGCTCTTTGCAGAAACATCGTCGCAAACACACTGGAGAGCGGCCGTATGCCTGCGAGTTTTGTCCCATGCGTTTTACTGCTTTAAATATATTGAAAAATCATCGTCGTACTCACACCGGCGAAAAGCCATTCAAATGTGAATATTGTAATAAAAGTTTTTCACAAAAGGGCGATTGTCAGATGCATCAAAGGACTCATGGTGAAAAGGATTTCAGCTGCGTGTGCGGCGCTAAATTTTCGAAGTCTTCGAATTTACGTTATCATAGGCGAAGACAACATTGCCGATTTTCAGATGGAGATGCCACAAGCGAACAAGATGCCATGGATGATGCAGAAATGCATATAACTTTAGTAAAAGATGAAGATGGTGACGAACTTATTACTATCTCTACAAAGGGAGAACGAGAGAACGCAAATAAACATAAGCTCGGACTTGGTACACAAAACGAAGAGGAATTGTTGGACATTGCCATGGAAGATATATGTTAA
Protein Sequence: MDVEKICRTCLTLNGPLLSIYDDGKGGSGCLADMLREFTKTKPQCNDNLPERVCLSCISEINRCYSFKLKCENSSKTLQQLIPNAAKGLPDVTEKSVSNCEKAVQTNKKALISTYVQTFALFKDKEIQTEARDAMQNFKFERSSELSNAPRSNNPVRCFKRSTDLEANVHTLPRQKNPDKVCNRLCFDTNLKDTALKAAEMAREEAYILLDNSSTENDKFYIRSESDNIGAQDSINVVLSNHFEFYNDEDELDEDNRTEEHDYSCGNVDIPDINCATDQSLVANGVLCKINRHFDSASDEDGHSWDKEEHRATNSASSQLADKQSGPVAIISSSRLDSNREEYRCPYCIMTFVSLKTLRRHLSKRHNLELEPSQIIIEKKVKKSVETIEEMIDESAGNEQKNLTKGNVLKPHLMPRDRVSTSKSDEAALTTFQYFCDYCKAGFALRKTLTLHMNQNLCTSNNFKCDTCGKIFLTEKNLEAHIATHTNEQTCLECKKTCGSIEELSAHMISEHNRNPRNQCKVCKKVFTMKTSLMDHMRIHSGEKPFLCTICGKSFRQNSNLRQHLMRHTNEKNFKCDVCLNAYVTKAELFSHKRSHTGDHPFNCEICGSSFTSSSSLQKHRRKHTGERPYACEFCPMRFTALNILKNHRRTHTGEKPFKCEYCNKSFSQKGDCQMHQRTHGEKDFSCVCGAKFSKSSNLRYHRRRQHCRFSDGDATSEQDAMDDAEMHITLVKDEDGDELITISTKGERENANKHKLGLGTQNEEELLDIAMEDIC

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00749874;
90% Identity: iTF_00748402;
80% Identity: -